Development of a bioluminescent nitroreductase probe for preclinical imaging

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Vorobyeva, Anzhelika G ^a   Stanton, Michael ^b   Godinat, Aurélien ^a   Lund, Kjetil B ^c,d   Karateev, Grigory G ^a   Francis, Kevin P ^e   Allen, Elizabeth ^a   Gelovani, Juri G ^f   McCormack, Emmet ^c,d   Tangney, Mark ^b   Dubikovskaya, Elena A ^a  

^a EPFL   (Switzerland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c UNIVERSITY OF BERGEN   (Norway)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^e PERKINELMER INC   (United States)

^f Wayne State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; FLUORESCENT DYE; NITROREDUCTASE; NITROREDUCTASE CAGED LUCIFERIN; UNCLASSIFIED DRUG; PRODRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BIOLUMINESCENCE; CANCER CELL LINE; CONTROLLED STUDY; ENZYME ANALYSIS; ESCHERICHIA COLI; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE DIRECTED ENZYME PRODRUG THERAPY; HUMAN; IMAGING AND DISPLAY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR PROBE; MOUSE; NONHUMAN; PRECLINICAL IMAGING; PROTEIN EXPRESSION; SKIN CANCER; THIGH; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; DIAGNOSTIC IMAGING; GENE THERAPY; LUMINESCENCE; METABOLISM; NEOPLASMS; PROCEDURES;

BACTERIA (MICROORGANISMS); MAMMALIA;

ANIMALS; CELL LINE; DIAGNOSTIC IMAGING; FEMALE; GENETIC THERAPY; HUMANS; LUMINESCENT MEASUREMENTS; MICE; MICE, INBRED BALB C; NEOPLASMS; NITROREDUCTASES; PRODRUGS;

EID: 84938391974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131037     Document Type: Article

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