NK cells inhibit humoral immunity by reducing the abundance of CD4+ T follicular helper cells during a chronic virus infection

Journal of Leukocyte Biology

Volumn 98, Issue 2, 2015, Pages 153-162

  Cook, Kevin D ^a   Kline, Hannah C ^a   Whitmire, Jason K ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Antibody; Host defense; Immune regulation; Lymphocytic choriomeningitis virus; Mice

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; VIRUS ANTIBODY; HLA ANTIGEN CLASS 1; INTERFERON; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NCR1 PROTEIN, HUMAN;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARENAVIRUS INFECTION; ARTICLE; B LYMPHOCYTE; CD4+ T FOLLICULAR HELPER CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CHRONIC DISEASE; CONTROLLED STUDY; FLOW CYTOMETRY; HELPER CELL; HUMORAL IMMUNITY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PLASMABLAST; PRIORITY JOURNAL; T CELL DEPLETION; VIRAL CLEARANCE; ANIMAL; DENDRITIC CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; PATHOLOGY; SIGNAL TRANSDUCTION; VIROLOGY; VIRUS INFECTION;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS;

ADAPTIVE IMMUNITY; ANIMALS; B-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNITY, HUMORAL; INTERFERON TYPE I; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE DEPLETION; MICE; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; VIRUS DISEASES;

EID: 84938356833     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.4HI1214-594R     Document Type: Article

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