Metabolome disruption of the rat cerebrum induced by the acute toxic effects of the synthetic cannabinoid MAM-2201

Life Sciences

Volumn 137, Issue , 2015, Pages 49-55

  Zaitsu, Kei ^a,b   Hayashi, Yumi ^a,b   Suzuki, Kei ^a   Nakayama, Hiroshi ^a   Hattori, Nanpei ^a   Takahara, Rina ^a   Kusano, Maiko ^a   Tsuchihashi, Hitoshi ^a,c   Ishii, Akira ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Cerebrum; Energy metabolism disruption; MAM 2201; Metabolomics; Synthetic cannabinoid

Indexed keywords

CANNABINOID; GLUTAMIC ACID; MALIC ACID; MAM 2201; SUCCINIC ACID; UNCLASSIFIED DRUG; 1-(5-FLUOROPENTYL)-3-(4-METHYL-1-NAPHTHOYL)INDOLE; INDOLE DERIVATIVE; NAPHTHALENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCLING BEHAVIOR; CITRIC ACID CYCLE; CONTROLLED STUDY; ENERGY METABOLISM; GAS CHROMATOGRAPHY; GLUTAMATERGIC SYNAPSE; HYPOKINESIA; MALE; METABOLITE; METABOLOME; METABOLOMICS; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; RAT; TANDEM MASS SPECTROMETRY; ANIMAL; BRAIN; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; DYSPNEA; LOCOMOTION; METABOLISM; SEIZURE;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; CANNABINOIDS; CEREBRUM; CITRIC ACID CYCLE; DOSE-RESPONSE RELATIONSHIP, DRUG; DYSPNEA; GLUTAMIC ACID; HYPOKINESIA; INDOLES; LOCOMOTION; MALE; METABOLOME; NAPHTHALENES; RATS; SEIZURES;

EID: 84938312255     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.05.013     Document Type: Article

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