-
1
-
-
74749088219
-
Neuroblastoma: Biology, prognosis, and treatment
-
Park, J.R., Eggert, A. & Caron, H. Neuroblastoma: Biology, prognosis, and treatment. Hematol. Oncol. Clin. North Am. 24, 65-86 (2010).
-
(2010)
Hematol. Oncol. Clin. North Am
, vol.24
, pp. 65-86
-
-
Park, J.R.1
Eggert, A.2
Caron, H.3
-
2
-
-
58249093955
-
The International Neuroblastoma Risk Group (INRG) classification system: An INRG Task Force report
-
Cohn, S.L. et al. The International Neuroblastoma Risk Group (INRG) classification system: An INRG Task Force report. J. Clin. Oncol. 27, 289-297 (2009).
-
(2009)
J. Clin. Oncol
, vol.27
, pp. 289-297
-
-
Cohn, S.L.1
-
3
-
-
0021261878
-
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
-
Brodeur, G.M., Seeger, R.C., Schwab, M., Varmus, H.E. & Bishop, J.M. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 224, 1121-1124 (1984).
-
(1984)
Science
, vol.224
, pp. 1121-1124
-
-
Brodeur, G.M.1
Seeger, R.C.2
Schwab, M.3
Varmus, H.E.4
Bishop, J.M.5
-
4
-
-
79961002472
-
High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma
-
Schulte, J.H. et al. High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma. Clin. Cancer Res. 17, 5082-5092 (2011).
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 5082-5092
-
-
Schulte, J.H.1
-
5
-
-
84871982155
-
Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma
-
Sausen, M. et al. Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma. Nat. Genet. 45, 12-17 (2013).
-
(2013)
Nat. Genet
, vol.45
, pp. 12-17
-
-
Sausen, M.1
-
6
-
-
84874664731
-
The genetic landscape of high-risk neuroblastoma
-
Pugh, T.J. et al. The genetic landscape of high-risk neuroblastoma. Nat. Genet. 45, 279-284 (2013).
-
(2013)
Nat. Genet
, vol.45
, pp. 279-284
-
-
Pugh, T.J.1
-
7
-
-
84858248558
-
Association of age at diagnosis and genetic mutations in patients with neuroblastoma
-
Cheung, N.-K.V. et al. Association of age at diagnosis and genetic mutations in patients with neuroblastoma. J. Am. Med. Assoc. 307, 1062-1071 (2012).
-
(2012)
J. Am. Med. Assoc
, vol.307
, pp. 1062-1071
-
-
Cheung, N.-K.V.1
-
8
-
-
54049149961
-
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
-
Janoueix-Lerosey, I. et al. Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature 455, 967-970 (2008).
-
(2008)
Nature
, vol.455
, pp. 967-970
-
-
Janoueix-Lerosey, I.1
-
9
-
-
54049094708
-
Identification of ALK as a major familial neuroblastoma predisposition gene
-
Mossé, Y.P. et al. Identification of ALK as a major familial neuroblastoma predisposition gene. Nature 455, 930-935 (2008).
-
(2008)
Nature
, vol.455
, pp. 930-935
-
-
Mossé, Y.P.1
-
10
-
-
84906819212
-
Emergence of new ALK mutations at relapse of neuroblastoma
-
Schleiermacher, G. et al. Emergence of new ALK mutations at relapse of neuroblastoma. J. Clin. Oncol. 32, 2727-2734 (2014).
-
(2014)
J. Clin. Oncol
, vol.32
, pp. 2727-2734
-
-
Schleiermacher, G.1
-
11
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov, L.B. et al. Signatures of mutational processes in human cancer. Nature 500, 415-421 (2013).
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
-
12
-
-
84886297667
-
Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases
-
Cobrinik, D. et al. Recurrent pre-existing and acquired DNA copy number alterations, including focal TERT gains, in neuroblastoma central nervous system metastases. Genes Chromosom. Cancer 52, 1150-1166 (2013).
-
(2013)
Genes Chromosom. Cancer
, vol.52
, pp. 1150-1166
-
-
Cobrinik, D.1
-
13
-
-
0031665929
-
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization
-
Vandesompele, J. et al. Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization. Genes Chromosom. Cancer 23, 141-152 (1998).
-
(1998)
Genes Chromosom. Cancer
, vol.23
, pp. 141-152
-
-
Vandesompele, J.1
-
14
-
-
70949098060
-
Combined immunodeficiency associated with DOCK8 mutations
-
Zhang, Q. et al. Combined immunodeficiency associated with DOCK8 mutations. N. Engl. J. Med. 361, 2046-2055 (2009).
-
(2009)
N. Engl. J. Med
, vol.361
, pp. 2046-2055
-
-
Zhang, Q.1
-
15
-
-
84923068934
-
The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking
-
Belle, L. et al. The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking. Sci. Signal. 8, ra18 (2015).
-
(2015)
Sci. Signal
, vol.8
, pp. ra18
-
-
Belle, L.1
-
16
-
-
84859216598
-
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
-
Molenaar, J.J. et al. Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature 483, 589-593 (2012).
-
(2012)
Nature
, vol.483
, pp. 589-593
-
-
Molenaar, J.J.1
-
17
-
-
63449111226
-
Heterogeneity of the MYCN oncogene in neuroblastoma
-
Theissen, J. et al. Heterogeneity of the MYCN oncogene in neuroblastoma. Clin. Cancer Res. 15, 2085-2090 (2009).
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 2085-2090
-
-
Theissen, J.1
-
18
-
-
84856555606
-
Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways
-
Shukla, N. et al. Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways. Clin. Cancer Res. 18, 748-757 (2012).
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 748-757
-
-
Shukla, N.1
-
19
-
-
84858238452
-
Mechanisms of CHD5 inactivation in neuroblastomas
-
Koyama, H. et al. Mechanisms of CHD5 inactivation in neuroblastomas. Clin. Cancer Res. 18, 1588-1597 (2012).
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 1588-1597
-
-
Koyama, H.1
-
20
-
-
46849107117
-
CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas
-
Fujita, T. et al. CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas. J. Natl. Cancer Inst. 100, 940-949 (2008).
-
(2008)
J. Natl. Cancer Inst
, vol.100
, pp. 940-949
-
-
Fujita, T.1
-
21
-
-
84902315822
-
High-definition reconstruction of clonal composition in cancer
-
Fischer, A., Vázquez-Garciá, I., Illingworth, C.J. & Mustonen, V. High-definition reconstruction of clonal composition in cancer. Cell Rep. 7, 1740-1752 (2014).
-
(2014)
Cell Rep
, vol.7
, pp. 1740-1752
-
-
Fischer, A.1
-
22
-
-
84904744663
-
Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer
-
Luo, Y. et al. Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology 147, 418.e8-429.e8 (2014).
-
(2014)
Gastroenterology
, vol.147
, pp. 418e8-429e8
-
-
Luo, Y.1
-
23
-
-
84929712250
-
Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial
-
Wiestler, B. et al. Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial. Neuro-oncol. 16, 1630-1638 (2014).
-
(2014)
Neuro-oncol
, vol.16
, pp. 1630-1638
-
-
Wiestler, B.1
-
24
-
-
70450222311
-
Cellular signaling of Dock family proteins in neural function
-
Miyamoto, Y. & Yamauchi, J. Cellular signaling of Dock family proteins in neural function. Cell. Signal. 22, 175-182 (2010).
-
(2010)
Cell. Signal
, vol.22
, pp. 175-182
-
-
Miyamoto, Y.1
Yamauchi, J.2
-
25
-
-
38149118052
-
Dedicator of cytokinesis 8 is disrupted in two patients with mental retardation and developmental disabilities
-
Griggs, B.L., Ladd, S., Saul, R.A., DuPont, B.R. & Srivastava, A.K. Dedicator of cytokinesis 8 is disrupted in two patients with mental retardation and developmental disabilities. Genomics 91, 195-202 (2008).
-
(2008)
Genomics
, vol.91
, pp. 195-202
-
-
Griggs, B.L.1
Ladd, S.2
Saul, R.A.3
DuPont, B.R.4
Srivastava, A.K.5
-
26
-
-
34548409923
-
Association of deletion 9p 46, XY gonadal dysgenesis and autistic spectrum disorder
-
Vinci, G. et al. Association of deletion 9p, 46, XY gonadal dysgenesis and autistic spectrum disorder. Mol. Hum. Reprod. 13, 685-689 (2007).
-
(2007)
Mol. Hum. Reprod
, vol.13
, pp. 685-689
-
-
Vinci, G.1
-
27
-
-
79551628428
-
Treatment and outcomes of patients with relapsed, high-risk neuroblastoma: Results of German trials
-
Simon, T. et al. Treatment and outcomes of patients with relapsed, high-risk neuroblastoma: Results of German trials. Pediatr. Blood Cancer 56, 578-583 (2011).
-
(2011)
Pediatr. Blood Cancer
, vol.56
, pp. 578-583
-
-
Simon, T.1
-
28
-
-
84904024982
-
KRAS and YAP1 converge to regulate EMT and tumor survival
-
Shao, D.D. et al. KRAS and YAP1 converge to regulate EMT and tumor survival. Cell 158, 171-184 (2014).
-
(2014)
Cell
, vol.158
, pp. 171-184
-
-
Shao, D.D.1
-
29
-
-
84903984143
-
Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer
-
Kapoor, A. et al. Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. Cell 158, 185-197 (2014).
-
(2014)
Cell
, vol.158
, pp. 185-197
-
-
Kapoor, A.1
-
30
-
-
84923957819
-
The Hippo effector YAP promotes resistance to RAF-and MEK-targeted cancer therapies
-
Lin, L. et al. The Hippo effector YAP promotes resistance to RAF-and MEK-targeted cancer therapies. Nat. Genet. 47, 250-256 (2015).
-
(2015)
Nat. Genet
, vol.47
, pp. 250-256
-
-
Lin, L.1
-
31
-
-
84865558202
-
Purity Est: Estimating purity of human tumor samples using next-generation sequencing data
-
Su, X., Zhang, L., Zhang, J., Meric-Bernstam, F. & Weinstein, J.N. PurityEst: Estimating purity of human tumor samples using next-generation sequencing data. Bioinformatics 28, 2265-2266 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 2265-2266
-
-
Su, X.1
Zhang, L.2
Zhang, J.3
Meric-Bernstam, F.4
Weinstein, J.N.5
-
32
-
-
84866851740
-
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
-
Peifer, M. et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat. Genet. 44, 1104-1110 (2012).
-
(2012)
Nat. Genet
, vol.44
, pp. 1104-1110
-
-
Peifer, M.1
-
33
-
-
84881030814
-
Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3
-
Martin, M. et al. Exome sequencing identifies recurrent somatic mutations in EIF1AX and SF3B1 in uveal melanoma with disomy 3. Nat. Genet. 45, 933-936 (2013).
-
(2013)
Nat. Genet
, vol.45
, pp. 933-936
-
-
Martin, M.1
-
34
-
-
84867306721
-
Snakemake-a scalable bioinformatics workflow engine
-
Köster, J. & Rahmann, S. Snakemake-a scalable bioinformatics workflow engine. Bioinformatics 28, 2520-2522 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 2520-2522
-
-
Köster, J.1
Rahmann, S.2
-
35
-
-
84902188451
-
Chromosome 17/17q gain and unaltered profiles in high resolution array-CGH are prognostically informative in neuroblastoma
-
Theissen, J. et al. Chromosome 17/17q gain and unaltered profiles in high resolution array-CGH are prognostically informative in neuroblastoma. Genes Chromosom. Cancer 53, 639-649 (2014).
-
(2014)
Genes Chromosom. Cancer
, vol.53
, pp. 639-649
-
-
Theissen, J.1
-
36
-
-
84895783051
-
Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia
-
Oakes, C.C. et al. Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia. Cancer Discov. 4, 348-361 (2014).
-
(2014)
Cancer Discov
, vol.4
, pp. 348-361
-
-
Oakes, C.C.1
-
37
-
-
84872564830
-
A ?-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
-
Teschendorff, A.E. et al. A ?-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics 29, 189-196 (2013).
-
(2013)
Bioinformatics
, vol.29
, pp. 189-196
-
-
Teschendorff, A.E.1
-
38
-
-
84908566266
-
Comprehensive analysis of DNA methylation data with RnBeads
-
Assenov, Y. et al. Comprehensive analysis of DNA methylation data with RnBeads. Nat. Methods 11, 1138-1140 (2014).
-
(2014)
Nat. Methods
, vol.11
, pp. 1138-1140
-
-
Assenov, Y.1
-
39
-
-
84876919708
-
Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma
-
Kocak, H. et al. Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma. Cell Death Dis. 4, e586 (2013).
-
(2013)
Cell Death Dis
, vol.4
, pp. e586
-
-
Kocak, H.1
-
40
-
-
0023375195
-
The neighbor-joining method: A new method for reconstructing phylogenetic trees
-
Saitou, N. & Nei, M. The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4, 406-425 (1987).
-
(1987)
Mol. Biol. Evol
, vol.4
, pp. 406-425
-
-
Saitou, N.1
Nei, M.2
-
41
-
-
84864489995
-
T-REX: A web server for inferring, validating and visualizing phylogenetic trees and networks
-
Boc, A., Diallo, A.B. & Makarenkov, V. T-REX: A web server for inferring, validating and visualizing phylogenetic trees and networks. Nucleic Acids Res. 40, W573-W579 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. W573-W579
-
-
Boc, A.1
Diallo, A.B.2
Makarenkov, V.3
-
42
-
-
19944432172
-
Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA-and TrkB-expressing neuroblastomas
-
Schulte, J.H. et al. Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA-and TrkB-expressing neuroblastomas. Oncogene 24, 165-177 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 165-177
-
-
Schulte, J.H.1
-
43
-
-
84922242805
-
MIR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin
-
Althoff, K. et al. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. Int. J. Cancer 136, 1308-1320 (2015).
-
(2015)
Int. J. Cancer
, vol.136
, pp. 1308-1320
-
-
Althoff, K.1
-
44
-
-
57849107571
-
Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma
-
Otto, T. et al. Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma. Cancer Cell 15, 67-78 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 67-78
-
-
Otto, T.1
|