Activation of FoxO1/ PGC-1α prevents mitochondrial dysfunction and ameliorates mesangial cell injury in diabetic rats

Molecular and Cellular Endocrinology

Volumn 413, Issue , 2015, Pages 1-12

  Wu, Lina ^a   Wang, Qingzhu ^a   Guo, Feng ^a   Zhou, Yingni ^a   Ji, Hongfei ^a   Liu, Fei ^a   Ma, Xiaojun ^a   Zhao, Yanyan ^a   Qin, Guijun ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; Forkhead box class O1; Oxidative stress; Peroxisome proliferator activated receptor co activator 1

Indexed keywords

COLLAGEN TYPE 4; FIBRONECTIN; LENTIVIRUS VECTOR; MALONALDEHYDE; MESSENGER RNA; MITOFUSIN 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR NRF1; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, RAT; GLUCOSE; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; MITOFUSIN 2 PROTEIN, RAT; NERVE PROTEIN; PPARGC1A PROTEIN, RAT; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL PROTECTION; CELLULAR STRESS RESPONSE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; FOXO1 GENE; GENE; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MALE; MESANGIUM CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PGC 1ALPHA GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RAT; RENAL PROTECTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLUCOSE; MALE; MEMBRANE PROTEINS; MESANGIAL CELLS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTORS;

EID: 84938213275     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.06.007     Document Type: Article

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