Modeling correction of severe urea cycle defects in the growing murine liver using a hybrid recombinant adeno-associated virus/piggyBac transposase gene delivery system

Hepatology

Volumn 62, Issue 2, 2015, Pages 417-428

  Cunningham, Sharon C ^a,b   Siew, Susan M ^a   Hallwirth, Claus V ^a   Bolitho, Christine ^a   Sasaki, Natsuki ^a   Garg, Gagan ^a,c   Michael, Iacovos P ^d   Hetherington, Nicola A ^a   Carpenter, Kevin ^e   de Alencastro, Gustavo ^a   Nagy, Andras ^d,f   Alexander, Ian E ^a,g  

^a CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c MACQUARIE UNIVERSITY   (Australia)

^d MOUNT SINAI HOSPITAL   (Canada)

^e CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^f UNIVERSITY OF TORONTO   (Canada)

^g UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININOSUCCINATE SYNTHASE; CITRULLINE; ENHANCED GREEN FLUORESCENT PROTEIN; ORNITHINE CARBAMOYLTRANSFERASE; PARVOVIRUS VECTOR; PIGGYBAC TRANSPOSASE; TRANSPOSASE; UNCLASSIFIED DRUG; UREA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA MODIFICATION; DNA PURIFICATION; FEMALE; KNOCKOUT MOUSE; LIVER CELL; MALE; MOUSE; NEWBORN; NONHUMAN; ORNITHINE TRANSCARBAMYLASE DEFICIENCY; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; TRANSGENE; TRANSPOSON; UREA CYCLE DISORDER; VIRAL GENE DELIVERY SYSTEM; ADENOVIRIDAE; ANIMAL; DISEASE MODEL; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETICS; HUMAN; HYPERAMMONEMIA; LIVER DISEASES; METABOLISM; NONPARAMETRIC TEST; PHARMACOLOGY; PROCEDURES; SEVERITY OF ILLNESS INDEX; TRANSGENIC MOUSE;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; HUMANS; HYPERAMMONEMIA; LIVER DISEASES; MICE; MICE, TRANSGENIC; SEVERITY OF ILLNESS INDEX; STATISTICS, NONPARAMETRIC; UREA;

EID: 84938211382     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27842     Document Type: Article

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