RNA-directed repair of DNA double-strand breaks

DNA Repair

Volumn 32, Issue , 2015, Pages 82-85

  Yang, Yun Gui ^a,b   Qi, Yijun ^c,d  

^a Chinese Academy of Sciences   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c Tsinghua University   (China)

^d TSINGHUA UNIVERSITY   (China)

Author keywords

DiRNA; DNA damage response; DNA repair; Double strand break; MicroRNA; RNA

Indexed keywords

COMPLEMENTARY DNA; DOUBLE STRANDED DNA; LONG UNTRANSLATED RNA; MESSENGER RNA; MICRORNA; RIBONUCLEASE; RNA; RNA INDUCED SILENCING COMPLEX; SMALL UNTRANSLATED RNA; ARGONAUTE PROTEIN; DNA; EIF2C2 PROTEIN, HUMAN; RAD51 PROTEIN; RAD51 PROTEIN, HUMAN; RAD52 PROTEIN; RAD52 PROTEIN, HUMAN; RNA POLYMERASE II;

ARTICLE; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; EUKARYOTE EVOLUTION; GENOMIC INSTABILITY; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; SACCHAROMYCES CEREVISIAE; YEAST; CHEMISTRY; DOUBLE STRANDED DNA BREAK; GENE EXPRESSION REGULATION; GENETIC RECOMBINATION; GENETICS; HUMAN; METABOLISM; SIGNAL TRANSDUCTION;

EUKARYOTA;

ARGONAUTE PROTEINS; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; GENE EXPRESSION REGULATION; GENOMIC INSTABILITY; HUMANS; RAD51 RECOMBINASE; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; RECOMBINATION, GENETIC; RNA; RNA POLYMERASE II; SIGNAL TRANSDUCTION;

EID: 84938206786     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2015.04.017     Document Type: Article

References (70)

1. Iyama T., Wilson D.M. DNA repair mechanisms in dividing and non-dividing cells. DNA Repair (Amst.) 2013, 12(8):620-636.
2. Kavanagh J.N., et al. DNA double strand break repair: a radiation perspective. Antioxid. Redox Signal. 2013, 18(18):2458-2472.
3. West S.C., et al. Double-strand break repair in human cells. Cold Spring Harb. Symp. Quant. Biol. 2000, 65:315-321.
4. Dion V., Gasser S.M. Chromatin movement in the maintenance of genome stability. Cell 2013, 152(6):1355-1364.
5. Doksani Y., de Lange T. The role of double-strand break repair pathways at functional and dysfunctional telomeres. Cold Spring Harb. Perspect. Biol. 2014, 6(12).
6. Gong F., Miller K.M. Mammalian DNA repair: HATs and HDACs make their mark through histone acetylation. Mutat. Res. 2013, 750(1-2):23-30.
7. Goodarzi A.A., Jeggo P.A. The repair and signaling responses to DNA double-strand breaks. Adv. Genet. 2013, 82:1-45.
8. Price B.D., D'Andrea A.D. Chromatin remodeling at DNA double-strand breaks. Cell 2013, 152(6):1344-1354.
9. Vignard J., Mirey G., Salles B. Ionizing-radiation induced DNA double-strand breaks: a direct and indirect lighting up. Radiother. Oncol. 2013, 108(3):362-369.
10. d'Adda di Fagagna F. A direct role for small non-coding RNAs in DNA damage response. Trends Cell Biol. 2014, 24(3):171-178.
11. Ba Z., Qi Y. Small RNAs: emerging key players in DNA double-strand break repair. Sci. China Life Sci. 2013, 56(10):933-936.
12. Wan G., et al. miRNA response to DNA damage. Trends Biochem. Sci. 2011, 36(9):478-484.
13. Keskin H., et al. Transcript-RNA-templated DNA. recombination and repair. Nature 2014, 515(7527):436-439.
14. Yamanaka S., Siomi H. diRNA-Ago2-RAD51 complexes at double-strand break sites. Cell Res. 2014, 24(5):511-512.
15. Bottai G., et al. Targeting the microRNA-regulating DNA damage/repair pathways in cancer. Expert Opin. Biol. Ther. 2014, 14(11):1667-1683.
16. Garofalo M., Croce C.M. MicroRNAs as therapeutic targets in chemoresistance. Drug Resist. Updates 2013, 16(3-5):47-59.
17. Han C., et al. Crosstalk between the DNA damage response pathway and microRNAs. Cell Mol. Life Sci. 2012, 69(17):2895-2906.
18. Ofir M., Hacohen D., Ginsberg D. MiR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin E. Mol. Cancer Res. 2011, 9(4):440-447.
19. Wang P., et al. microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Res. 2009, 69(20):8157-8165.
20. Liu M., et al. Regulation of the cell cycle gene: BTG2, by miR-21 in human laryngeal carcinoma. Cell Res. 2009, 19(7):828-837.
21. Zhang D.G., Zheng J.N., Pei D.S. P53/microRNA-34-induced metabolic regulation: new opportunities in anticancer therapy. Mol. Cancer 2014, 13:115.
22. Zhou J.Y., et al. Analysis of microRNA expression profiles during the cell cycle in synchronized HeLa cells. BMB Rep. 2009, 42(9):593-598.
23. Sun X., et al. Let-7: a regulator of the ERalpha signaling pathway in human breast tumors and breast cancer stem cells. Oncol. Rep. 2013, 29(5):2079-2087.
24. de Oliveira P.E., et al. Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21. Cell Cycle 2009, 8(19):3157-3164.
25. Rahman M., et al. miR-15b/16-2 regulates factors that promote p53 phosphorylation and augments the DNA damage response following radiation in the lung. J. Biol. Chem. 2014, 289(38):26406-26416.
26. Zhang X., et al. Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway. Cancer Res. 2010, 70(18):7176-7186.
27. Boominathan L. The guardians of the genome (p53: TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network. Cancer Metastasis Rev. 2010, 29(4):613-639.
28. Cha Y.H., et al. MiRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling. Cell Cycle 2012, 11(7):1273-1281.
29. Chang T.C., et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell 2007, 26(5):745-752.
30. He L., et al. A microRNA component of the p53 tumour suppressor network. Nature 2007, 447(7148):1130-1134.
31. Kim N.H., et al. p53 regulates nuclear GSK-3 levels through miR-34-mediated Axin2 suppression in colorectal cancer cells. Cell Cycle 2013, 12(10):1578-1587.
32. Tang H., et al. Let-7g microRNA sensitizes fluorouracil-resistant human hepatoma cells. Pharmazie 2014, 69(4):287-292.
33. Tzatsos A., et al. Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells. J. Biol. Chem. 2011, 286(38):33061-33069.
34. Johnson C.D., et al. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 2007, 67(16):7713-7722.
35. Lal A., et al. miR-24 Inhibits cell proliferation by targeting E2F2: MYC, and other cell-cycle genes via binding to seedless 3'UTR microRNA recognition elements. Mol. Cell 2009, 35(5):610-625.
36. Gupta S., et al. Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis. Cell Death Dis. 2012, 3:pe333.
37. Hackl M., et al. miR-17: miR-19b, miR-20a, and miR-106a are down-regulated in human aging. Aging Cell 2010, 9(2):291-296.
38. Dmitriev P., et al. Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients. J. Biol. Chem. 2013, 288(49):34989-35002.
39. Mueller A.C., Sun D., Dutta A. The miR-99 family regulates the DNA damage response through its target SNF2H. Oncogene 2013, 32(9):1164-1172.
40. Ivanovska I., et al. MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol. Cell Biol. 2008, 28(7):2167-2174.
41. Trompeter H.I., et al. MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC. PLoS One 2011, 6(1):e16138.
42. Yang G., et al. MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status. J. Mol. Med. (Berl.) 2011, 89(10):1037-1050.
43. He S., et al. Aurora kinase A induces miR-17-92 cluster through regulation of E2F1 transcription factor. Cell Mol. Life Sci. 2010, 67(12):2069-2076.
44. Cloonan N., et al. The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition. Genome Biol. 2008, 9(8):R127.
45. Di Francesco A., et al. The DNA-damage response to gamma-radiation is affected by miR-27a in A549 cells. Int. J. Mol. Sci. 2013, 14(9):17881-17896.
46. Martin N.T., et al. ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response. PLoS Genet. 2013, 9(5):e1003505.
47. Yan D., et al. Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS One 2010, 5(7):e11397.
48. Zhu F., et al. MicroRNA-124 (miR-124) regulates Ku70 expression and is correlated with neuronal death induced by ischemia/reperfusion. J. Mol. Neurosci. 2014, 52(1):148-155.
49. Chen S., et al. Radiosensitizing effects of ectopic miR-101 on non-small-cell lung cancer cells depend on the endogenous miR-101 level. Int. J. Radiat. Oncol. Biol. Phys. 2011, 81(5):1524-1529.
50. Wang Y., et al. MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Mol. Cancer Res. 2011, 9(8):1100-1111.
51. Lal A., et al. miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells. Nat. Struct. Mol. Biol. 2009, 16(5):492-498.
52. Krishnan K., et al. MicroRNA-182-5p targets a network of genes involved in DNA repair. RNA 2013, 19(2):230-242.
53. Moskwa P., et al. miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol. Cell 2011, 41(2):210-220.
54. Wang Y., et al. MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition. Cancer Res. 2012, 72(16):4037-4046.
55. Shen J., et al. A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. Carcinogenesis 2008, 29(10):1963-1966.
56. Liu W.J., et al. MLH1 as a direct target of MiR-155 and a potential predictor of favorable prognosis in pancreatic cancer. J. Gastrointest. Surg. 2013, 17(8):1399-1405.
57. Valeri N., et al. Modulation of mismatch repair and genomic stability by miR-155. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(15):6982-6987.
58. Wei W., et al. A role for small RNAs in DNA double-strand break repair. Cell 2012, 149(1):101-112.
59. Francia S., et al. Site-specific DICER and DROSHA RNA. products control the DNA-damage response. Nature 2012, 488(7410):231-235.
60. Michalik K.M., Bottcher R., Forstemann K. A small RNA response at DNA ends in Drosophila. Nucleic Acids Res. 2012, 40(19):9596-9603.
61. Gao M., et al. Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination. Cell Res. 2014, 24(5):532-541.
62. Storici F., et al. RNA-templated DNA repair. Nature 2007, 447(7142):338-341.
63. Keskin H., et al. Transcript-RNA-templated DNA recombination and repair. Nature 2014, 515(7527):436-439.
64. Derrien T., et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 2012, 22(9):1775-1789.
65. Harrow J., et al. GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res. 2012, 22(9):1760-1774.
66. Kataoka M., Wang D.Z. Non-coding RNAs including miRNAs and lncRNAs in cardiovascular biology and disease. Cells 2014, 3(3):883-898.
67. Rossi M.N., Antonangeli F. LncRNAs: new players in apoptosis control. Int. J. Cell Biol. 2014, 2014:473857.
68. Zhu J., et al. Function of lncRNAs and approaches to lncRNA-protein interactions. Sci. China Life Sci. 2013, 56(10):876-885.
69. Guenzl P.M., Barlow D.P. Macro lncRNAs: a new layer of cis-regulatory information in the mammalian genome. RNA Biol. 2012, 9(6):731-741.
70. Novikova I.V., et al. Rise of the RNA machines: exploring the structure of long non-coding RNAs. J. Mol. Biol. 2013, 425(19):3731-3746.