MiR-15b/16-2 regulates factors that promote p53 phosphorylation and augments the DNA damage response following radiation in the lung

Journal of Biological Chemistry

Volumn 289, Issue 38, 2014, Pages 26406-26416

  Rahman, Mohammad ^a   Lovat, Francesca ^b   Romano, Giulia ^b   Calore, Federica ^b   Acunzo, Mario ^b   Bell, Erica Hlavin ^b,c   Nana Sinkam, Patrick ^a,c  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DAMAGE RESPONSE;

ATR PROTEIN; CHECKPOINT KINASE 1; DNA; MICRORNA 15B; MICRORNA 16; MICRORNA 16 2; PROTEIN KINASE WIP1; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ATM PROTEIN; ATM PROTEIN, HUMAN; MICRORNA; MIRN15 MICRORNA, HUMAN; MIRN16 MICRORNA, HUMAN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE; PROTEIN PHOSPHATASE 2C; TP53 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CELL CYCLE ARREST; CELL PROTECTION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; G2 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; IONIZING RADIATION; LUNG ALVEOLUS EPITHELIUM; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RADIATION EXPOSURE; RADIATION INJURY; SIGNAL TRANSDUCTION; TIME; UPREGULATION; 3' UNTRANSLATED REGION; BINDING SITE; CELL LINE; EPITHELIUM CELL; GENETICS; LUNG; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; RADIATION RESPONSE; RESPIRATORY TRACT MUCOSA; RNA INTERFERENCE;

3' UNTRANSLATED REGIONS; APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA DAMAGE; DNA REPAIR; EPITHELIAL CELLS; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; LUNG; MICRORNAS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; RESPIRATORY MUCOSA; RNA INTERFERENCE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84907222766     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.573592     Document Type: Article

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