Let-7 g microRNA sensitizes fluorouracil-resistant human hepatoma cells

Pharmazie

Volumn 69, Issue 4, 2014, Pages 287-292

  Tang, Huifang ^a   Zhang, Pengfei ^a   Xiang, Qiong ^a   Yin, Jie ^a   Yu, Jia ^a   Yang, Xiaoyan ^a   Lei, Xiaoyong ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CYCLIN A; FLUOROURACIL; HIGH MOBILITY GROUP A2 PROTEIN; MICRORNA;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; DOWN REGULATION; DRUG INHIBITION; DRUG RESISTANCE; DRUG SENSITIVITY; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GROWTH INHIBITION; HEPATOMA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIVER CELL CARCINOMA; MTT ASSAY; PLASMID;

ANTIMETABOLITES, ANTINEOPLASTIC; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; COLORING AGENTS; CYCLIN A; DOWN-REGULATION; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; FLUOROURACIL; GENETIC VECTORS; HMGA2 PROTEIN; HUMANS; LIVER NEOPLASMS; MICRORNAS; REAL-TIME POLYMERASE CHAIN REACTION; TETRAZOLIUM SALTS; THIAZOLES; TRANSFECTION;

EID: 84898882553     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2014.3849     Document Type: Article

References (22)

1. Baird RD, Kaye SB (2003) Drug resistance reversal-are we getting closer ? Eur J Cancer 39: 2450-2461. (Pubitemid 37340159)
2. Ambros V (2003) MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 113: 673-676.
3. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838. (Pubitemid 40839735)
4. Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ (2005) RAS is regulated by the let-7 microRNA family. Cell 120: 635-647. (Pubitemid 40343076)
5. Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, Harano T, Yatabe Y, Nagino M, Nimura Y, Mitsudomi T, Takahashi T (2004) Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64: 3753-3756. (Pubitemid 38697282)
6. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt RL, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris CC, Croce CM (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261. (Pubitemid 43271657)
7. Calin GA, Liu CG, Sevignani C, Ferracin M, Felli N, Dumitru CD, Shimizu M, Cimmino A, Zupo S, Dono M, Dell'Aquila ML, Alder H, Rassenti L, Kipps TJ, Bullrich F, Negrini M, Croce CM (2004) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 101: 11755-11760. (Pubitemid 39095368)
8. He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, Powers S, Cordon-Cardo C, Lowe SW, Hannon GJ, Hammond SM A (2005) microRNA polycistron as a potential human oncogene. Nature 435: 828-833. (Pubitemid 40839734)
9. Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE (2006) The colorectal microRNAome. Proc. Natl. Acad. Sci. USA 103: 3687-3692. (Pubitemid 43376616)
10. Reeves R (2001) Molecular biology of HMGA proteins: hubs of nuclear function. Gene 277: 63-81.
11. Boo LM, Lin HH, Chung V, Zhou B, Louie SG, O'Reilly MA, Yen Y, Ann DK (2005) High mobility group A2 potentiates genotoxic stress in part through the modulation of basal and DNA damage-dependent phosphatidylinositol 3-kinase-related protein kinase activation. Cancer Res 65: 6622-6630. (Pubitemid 41060698)
12. Reeves R (2001) Beckerbauer LHMGI/Y proteins: flexible regulators of transcription and chromatin structure.Biochim Biophys Acta 1519: 13-29.
13. Chiappetta G, Avantaggiato V, Visconti R, Fedele M, Battista S, Trapasso F, Merciai BM, Fidanza V, Giancotti V, Santoro M, Simeone A, Fusco A (1996) High level expression of the HMGI (Y) gene during embryonic development.Oncogene [13:] 2439-2446.
14. Rogalla P, Drechsler K, Frey G, Hennig Y, Helmke B, Bonk U, Bullerdiek J (1996) HMGI-C expression patterns in human tissues. Implications for the genesis of frequent mesenchymal tumors.Am J Pathol 149: 775-779. (Pubitemid 26334162)
15. Tessari MA, Gostissa M, Altamura S, Sgarra R, Rustighi A, Salvagno C, Caretti G, Imbriano C, Mantovani R, Del Sal G, Giancotti V, Manfioletti G (2003) Transcriptional activation of the cyclin A gene by the architectural transcription factor HMGA2.Mol Cell Biol 23: 9104-9116. (Pubitemid 37499800)
16. Lee YS, Dutta A (2007) The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.Genes Dev 21: 1025-1030.
17. Boyerinas B, Park SM, Shomron N, Hedegaard MM, Vinther J, Andersen JS, Feig C, Xu J, Burge CB, Peter ME (2008) Identification of let-7-regulated oncofetal genes.Cancer Res 68: 2587-2591. (Pubitemid 351556256)
18. Park SM, Shell S, Radjabi AR, Schickel R, Feig C, Boyerinas B, Dinulescu DM, Lengyel E, Peter ME (2007) Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2. Cell Cycle 6: 2585-2590. (Pubitemid 350224037)
19. Doench JG, Sharp PA (2004) Specificity of microRNA target selection in translational repression.Genes Dev 18: 504-511. (Pubitemid 38372808)
20. Yang N, Coukos G, Zhang L (2008) MicroRNA epigenetic alterations in human cancer: one step forward in diagnosis and treatment.Int J Cancer 122: 963-968. (Pubitemid 351213992)
21. Wurdinger T, Costa FF (2007) Molecular therapy in the microRNA era. Pharmacogen omics J 7: 297-304. (Pubitemid 47471308)
22. Malek A, Bakhidze E, Noske A, Sers C, Aigner A, Schäfer R, Tchernitsa O (2008) HMGA2 gene is a promising target for ovarian cancer silencing therapy. Int J Cancer 123: 348-356. (Pubitemid 351842019)