Aurora kinase A induces miR-17-92 cluster through regulation of E2F1 transcription factor

Cellular and Molecular Life Sciences

Volumn 67, Issue 12, 2010, Pages 2069-2076

  He, Shun ^a   Yang, Shangbin ^a   Deng, Guohua ^a   Liu, Mei ^a   Zhu, Hongxia ^a   Zhang, Wei ^a   Yan, Shuang ^a   Quan, Lanping ^a   Bai, Jinfeng ^a   Xu, Ningzhi ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

AURKA; E2F1; MiR 17 92; Transcription factor; Tumorigenesis

Indexed keywords

AURORA A KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 17 92; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR GATA; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CELL CYCLE PROGRESSION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; DNA REPLICATION; GEL MOBILITY SHIFT ASSAY; GENE CLUSTER; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; UPREGULATION;

CHROMATIN IMMUNOPRECIPITATION; E2F1 TRANSCRIPTION FACTOR; HUMANS; MICRORNAS; PHOSPHOTRANSFERASES; PROTEIN-SERINE-THREONINE KINASES; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION FACTORS;

EID: 77953001817     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0340-8     Document Type: Article

References (29)

1. JR Bischoff L Anderson Y Zhu K Mossie L Ng B Souza B Schryver P Flanagan F Clairvoyant C Ginther CS Chan M Novotny DJ Slamon GD Plowman 1998 A homologue of Drosophila Aurora kinase is oncogenic and amplified in human colorectal cancers EMBO J 17 3052 3065 10.1093/emboj/17.11.3052 1:CAS:528: DyaK1cXjvFeisro%3D 9606188 (Pubitemid 28254378)
2. YM Jeng SY Peng CY Lin HC Hsu 2004 Overexpression and amplification of Aurora-A in hepatocellular carcinoma Clin Cancer Res 10 2065 2071 10.1158/1078-0432.CCR-1057-03 1:CAS:528:DC%2BD2cXisVGksro%3D 15041727 (Pubitemid 38375568)
3. S Rojanala H Han RM Munoz W Browne R Nagle DD Von Hoff DJ Bearss 2004 The mitotic serine threonine kinase, Aurora-2, is a potential target for drug development in human pancreatic cancer Mol Cancer Ther 3 451 457 1:CAS:528:DC%2BD2cXivFyhu7g%3D 15078988
4. MM Tanner S Grenman A Koul O Johannsson P Meltzer T Pejovic A Borg JJ Isola 2000 Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer Clin Cancer Res 6 1833 1839 1:CAS:528:DC%2BD3cXktVWisL8%3D 10815905
5. T Watanabe I Imoto T Katahira A Hirasawa I Ishiwata M Emi M Takayama A Sato J Inazawa 2002 Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers Jpn J Cancer Res 93 1114 1122 1:CAS:528:DC%2BD3sXhvVeiug%3D%3D 12417041
6. H Zhou J Kuang L Zhong WL Kuo JW Gray A Sahin BR Brinkley S Sen 1998 Tumor amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation Nat Genet 20 189 193 10.1038/2496 1:CAS:528: DyaK1cXms1eis78%3D 9771714 (Pubitemid 28455454)
7. H Katayama K Sasai H Kawai ZM Yuan J Bondaruk F Suzuki S Fujii RB Arlinghaus BA Czerniak S Sen 2004 Phosphorylation by Aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53 Nat Genet 36 55 62 10.1038/ng1279 1:CAS:528:DC%2BD3sXhtVWhu77M 14702041 (Pubitemid 38056208)
8. S Sankaran DE Crone RE Palazzo JD Parvin 2007 Aurora-A kinase regulates breast cancer associated gene 1 inhibition of centrosome-dependent microtubule nucleation Cancer Res 67 11186 11194 10.1158/0008-5472.CAN-07-2578 1:CAS:528:DC%2BD2sXhtlyiurnE 18056443 (Pubitemid 350248543)
9. H Yang CC Ou RI Feldman SV Nicosia PA Kruk JQ Cheng 2004 Aurora-A kinase regulates telomerase activity through c-Myc in human ovarian and breast epithelial cells Cancer Res 64 463 467 10.1158/0008-5472.CAN-03-2907 1:CAS:528:DC%2BD2cXmsVWksg%3D%3D 14744757 (Pubitemid 38120883)
10. H Yang L He P Kruk SV Nicosia JQ Cheng 2006 Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells Int J Cancer 119 2304 2312 10.1002/ijc.22154 1:CAS:528:DC%2BD28XhtVylsL3K 16894566 (Pubitemid 44546949)
11. P Briassouli F Chan K Savage JS Reis-Filho S Linardopoulos 2007 Aurora-A regulation of nuclear factor-kappaB signaling by phosphorylation of IkappaBalpha Cancer Res 67 1689 1695 10.1158/0008-5472.CAN-06-2272 1:CAS:528: DC%2BD2sXhvVWqtLs%3D 17308110 (Pubitemid 46383395)
12. S Anand S Penrhyn-Lowe AR Venkitaraman 2003 Aurora-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol Cancer Cell 3 51 62 10.1016/S1535-6108(02)00235-0 1:CAS:528:DC%2BD3sXhtFamt7Y%3D 12559175 (Pubitemid 37443890)
13. B Govindarajan X Bai C Cohen H Zhong S Kilroy G Louis M Moses JL Arbiser 2003 Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling J Biol Chem 278 9790 9795 10.1074/jbc.M212929200 1:CAS:528:DC%2BD3sXhvV2hsrc%3D 12514183 (Pubitemid 36800479)
14. E Lees B Faha V Dulic SI Reed E Harlow 1992 Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner Genes Dev 6 1874 1885 10.1101/gad.6.10.1874 1:CAS:528:DyaK3sXpvVymtQ%3D%3D 1398067
15. K Woods JM Thomson SM Hammond 2007 Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors J Biol Chem 282 2130 2134 10.1074/jbc.C600252200 1:CAS:528:DC%2BD2sXmsVartQ%3D%3D 17135268 (Pubitemid 47076737)
16. H Cam BD Dynlacht 2003 Emerging roles for E2F: beyond the G1/S transition and DNA replication Cancer Cell 3 311 316 10.1016/S1535-6108(03)00080-1 1:CAS:528:DC%2BD3sXjsFGgsr0%3D 12726857 (Pubitemid 38340300)
17. H Pan C Yin NJ Dyson E Harlow L Yamasaki T Van Dyke 1998 Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors Mol Cell 2 283 292 10.1016/S1097-2765(00)80273-7 1:CAS:528: DyaK1cXmsVyqt7k%3D 9774967
18. N Dyson 1998 The regulation of E2F by pRB-family proteins Genes Dev 12 2245 2262 10.1101/gad.12.15.2245 1:CAS:528:DyaK1cXltlagu74%3D 9694791
19. JR Nevins 1998 Toward an understanding of the functional complexity of the E2F and retinoblastoma families Cell Growth Differ 9 585 593 1:CAS:528:DyaK1cXlsVWqtLs%3D 9716176
20. S Sen H Zhou RA White 1997 A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines Oncogene 14 2195 2200 10.1038/sj.onc.1201065 1:CAS:528:DyaK2sXjs1Gnt7c%3D 9174055
21. F Martelli T Hamilton DP Silver NE Sharpless N Bardeesy M Rokas RA DePinho DM Livingston SR Grossman 2001 p19ARF targets certain E2F species for degradation Proc Natl Acad Sci USA 98 4455 4460 10.1073/pnas.081061398 1:CAS:528:DC%2BD3MXjtVagt74%3D 11274364 (Pubitemid 32294998)
22. Y Sylvestre V De Guire E Querido UK Mukhopadhyay V Bourdeau F Major G Ferbeyre P Chartrand 2007 An E2F/miR-20a autoregulatory feedback loop J Biol Chem 282 2135 2143 10.1074/jbc.M608939200 1:CAS:528:DC%2BD2sXmsVarug%3D%3D 17135249 (Pubitemid 47076740)
23. L He JM Thomson MT Hemann E Hernando-Monge D Mu S Goodson S Powers C Cordon-Cardo SW Lowe GJ Hannon SM Hammond 2005 A microRNA polycistron as a potential human oncogene Nature 435 828 833 10.1038/nature03552 1:CAS:528:DC%2BD2MXkvVGgs70%3D 15944707 (Pubitemid 40839734)
24. KA O'Donnell EA Wentzel KI Zeller CV Dang JT Mendell 2005 c-Myc-regulated microRNAs modulate E2F1 expression Nature 435 839 843 10.1038/nature03677 15944709 (Pubitemid 40839736)
25. Y Tong T Eigler 2009 Transcriptional targets for pituitary tumor-transforming gene-1 J Mol Endocrinol 43 179 185 10.1677/JME-08-0176 1:CAS:528:DC%2BD1MXhsF2qt7vL 19433493
26. BT Martin K Strebhardt 2006 Polo-like kinase 1: target and regulator of transcriptional control Cell Cycle 5 2881 2885 1:CAS:528:DC%2BD2sXksVOit7g%3D 17172872
27. AA Dar A Belkhiri W El-Rifai 2009 The Aurora kinase A regulates GSK-3beta in gastric cancer cells Oncogene 28 866 875 10.1038/onc.2008.434 1:CAS:528:DC%2BD1cXhsVKlt7rI 19060929
28. WC Lin FT Lin JR Nevins 2001 Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation Genes Dev 15 1833 1844 1:CAS:528:DC%2BD3MXlsFanu7g%3D 11459832
29. JT Mendell 2008 miRiad roles for the miR-17-92 cluster in development and disease Cell 133 217 222 10.1016/j.cell.2008.04.001 1:CAS:528: DC%2BD1cXltlWnurY%3D 18423194 (Pubitemid 351508308)