Cerebral cortex, hippocampus, striatum and cerebellum show differential susceptibility to quinolinic acid-induced oxidative stress

Neurological Sciences

Volumn 36, Issue 8, 2015, Pages 1449-1456

  Vandresen Filho, Samuel ^a,b   Martins, Wagner Carbolin ^a   Bertoldo, Daniela Bohn ^a   Mancini, Gianni ^a   De Bem, Andreza Fabro ^a   Tasca, Carla Inês ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

Author keywords

Antioxidant enzymes; Oxidative stress; Quinolinic acid

Indexed keywords

QUINOLINIC ACID; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL GROUP; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; BRAIN TISSUE; CEREBELLUM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; TIME; ANALYSIS OF VARIANCE; ANATOMY AND HISTOLOGY; ANIMAL; BRAIN; CHEMICALLY INDUCED; DRUG EFFECTS; LIPID PEROXIDATION; METABOLISM; PHYSIOLOGY; SEIZURE;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CEREBELLUM; CEREBRAL CORTEX; CORPUS STRIATUM; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HIPPOCAMPUS; LIPID PEROXIDATION; MALE; MICE; OXIDATIVE STRESS; QUINOLINIC ACID; REACTIVE OXYGEN SPECIES; SEIZURES; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TIME FACTORS;

EID: 84938205189     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-015-2180-7     Document Type: Article

References (40)

1. Vandresen-Filho S, Severino PC, Constantino LC, Martins WC, Molz S, Dal-Cim T, Bertoldo DB, Silva FR, Tasca CI (2014) N-methyl-D-aspartate preconditioning prevents quinolinic acid-induced deregulation of glutamate and calcium homeostasis in mice hippocampus. Neurotox Res. doi:10.1007/s12640-014-9496-6
2. Stone TW (2001) Kynurenines in the CNS: from endogenous obscurity to therapeutic importance. Prog Neurobiol 64(2):185–218
3. Piermartiri TC, Vandresen-Filho S, de Araujo Herculano B, Martins WC, Dal’agnolo D, Stroeh E, Carqueja CL, Boeck CR, Tasca CI (2009) Atorvastatin prevents hippocampal cell death due to quinolinic acid-induced seizures in mice by increasing Akt phosphorylation and glutamate uptake. Neurotox Res 16(2):106–115
4. Tavares RG, Tasca CI, Santos CE, Wajner M, Souza DO, Dutra-Filho CS (2000) Quinolinic acid inhibits glutamate uptake into synaptic vesicles from rat brain. Neuro Report 11(2):249–253
5. Severino PC, Muller Gdo A, Vandresen-Filho S, Tasca CI (2011) Cell signaling in NMDA preconditioning and neuroprotection in convulsions induced by quinolinic acid. Life Sci 89(15–16):570–576
6. Torres FV, da Silva Filho M, Antunes C, Kalinine E, Antoniolli E, Portela LV, Souza DO, Tort AB (2010) Electrophysiological effects of guanosine and MK-801 in a quinolinic acid-induced seizure model. Exp Neurol 221(2):296–306
7. Zeni AL, Vandresen-Filho S, Dal-Cim T, Martins WC, Bertoldo DB, Maraschin M, Tasca CI (2014) Aloysia gratissima prevents cellular damage induced by glutamatergic excitotoxicity. J Pharm Pharmacol 66(9):1294–1302
8. Russi MA, Vandresen-Filho S, Rieger DK, Costa AP, Lopes MW, Cunha RM, Teixeira EH, Nascimento KS, Cavada BS, Tasca CI, Leal RB (2012) ConBr, a lectin from Canavalia brasiliensis seeds, protects against quinolinic acid-induced seizures in mice. Neurochem Res 37(2):288–297
9. Vandresen-Filho S, Hoeller AA, Herculano BA, Duzzioni M, Duarte FS, Piermartiri TC, Boeck CC, de Lima TC, Marino-Neto J, Tasca CI (2013) NMDA preconditioning attenuates cortical and hippocampal seizures induced by intracerebroventricular quinolinic acid infusion. Neurotox Res 24(1):55–62
10. Ganzella M, Jardim FM, Boeck CR, Vendite D (2006) Time course of oxidative events in the hippocampus following intracerebroventricular infusion of quinolinic acid in mice. Neurosci Res 55(4):397–402
11. Santamaria A, Salvatierra-Sanchez R, Vazquez-Roman B, Santiago-Lopez D, Villeda-Hernandez J, Galvan-Arzate S, Jimenez-Capdeville ME, Ali SF (2003) Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: in vitro and in vivo studies. J Neurochem 86(2):479–488
12. Vandresen-Filho S, de Araujo Herculano B, Franco JL, Boeck CR, Dafre AL, Tasca CI (2007) Evaluation of glutathione metabolism in NMDA preconditioning against quinolinic acid-induced seizures in mice cerebral cortex and hippocampus. Brain Res 1184:38–45
13. de Araujo Herculano B, Vandresen-Filho S, Martins WC, Boeck CR, Tasca CI (2011) NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3 K and MAPK/ERK signaling pathways. Behav Brain Res 219(1):92–97
14. Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82(1):70–77
15. Mancini G, de Oliveira J, Hort MA, Moreira EL, Ribeiro-do-Valle RM, Rocha JB, de Bem AF (2013) Diphenyl diselenide differently modulates cardiovascular redox responses in young adult and middle-aged low-density lipoprotein receptor knockout hypercholesterolemic mice. J Pharm Pharmacol 66(3):387–397
16. Hempel SL, Buettner GR, O’Malley YQ, Wessels DA, Flaherty DM (1999) Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: comparison with 2′,7′-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2′,7′-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123. Free Radic Biol Med 27(1–2):146–159
17. Carlberg I, Mannervik B (1985) Glutathione reductase. Methods Enzymol 113:484–490
18. Wendel A (1981) Glutathione peroxidase. Methods Enzymol 77:325–333
19. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193(1):265–275
20. Stone TW (1993) Neuropharmacology of quinolinic and kynurenic acids. Pharmacol Rev 45(3):309–379
21. Behan WM, McDonald M, Darlington LG, Stone TW (1999) Oxidative stress as a mechanism for quinolinic acid-induced hippocampal damage: protection by melatonin and deprenyl. Br J Pharmacol 128(8):1754–1760
22. Stone TW, Behan WM, MacDonald M, Darlington LG (2000) Possible mediation of quinolinic acid-induced hippocampal damage by reactive oxygen species. Amino Acids 19(1):275–281
23. Schwarcz R, Kohler C (1983) Differential vulnerability of central neurons of the rat to quinolinic acid. Neurosci Lett 38(1):85–90
24. Schwarcz R, Pellicciari R (2002) Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities. J Pharmacol Exp Ther 303(1):1–10
25. Maharaj H, Maharaj DS, Daya S (2006) Acetylsalicylic acid and acetaminophen protect against oxidative neurotoxicity. Metab Brain Dis 21(2–3):189–199
26. Kuo A, Smith MT (2014) Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review. J Neurosci Methods 233:166–171
27. Celso Constantino L, Tasca CI, Boeck CR (2014) The role of NMDA receptors in the development of brain resistance through pre- and postconditioning. Aging Dis 5(6):430–441
28. Vizi ES, Kisfali M, Lorincz T (2013) Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects. Brain Res Bull 93:32–38
29. Guillemin GJ (2012) Quinolinic acid, the inescapable neurotoxin. FEBS J 279(8):1356–1365
30. Hassoun EA, Al-Ghafri M, Abushaban A (2003) The role of antioxidant enzymes in TCDD-induced oxidative stress in various brain regions of rats after subchronic exposure. Free Radic Biol Med 35(9):1028–1036
31. Brannan TS, Maker HS, Weiss C, Cohen G (1980) Regional distribution of glutathione peroxidase in the adult rat brain. J Neurochem 35(4):1013–1014
32. Maher P (2005) The effects of stress and aging on glutathione metabolism. Ageing Res Rev 4(2):288–314
33. Cardoso S, Santos MS, Seica R, Moreira PI (2010) Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. Biochim Biophys Acta 1802(11):942–951
34. Siqueira IR, Fochesatto C, de Andrade A, Santos M, Hagen M, Bello-Klein A, Netto CA (2005) Total antioxidant capacity is impaired in different structures from aged rat brain. Int J Dev Neurosci 23(8):663–671
35. Candelario-Jalil E, Mhadu NH, Al-Dalain SM, Martinez G, Leon OS (2001) Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils. Neurosci Res 41(3):233–241
36. Perez-Severiano F, Montes S, Geronimo-Olvera C, Segovia J (2013) Study of oxidative damage and antioxidant systems in two Huntington’s disease rodent models. Methods Mol Biol 1010:177–200
37. Fatokun AA, Smith RA, Stone TW (2008) Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons. Brain Res 1215:200–207
38. Yan E, Castillo-Melendez M, Smythe G, Walker D (2005) Quinolinic acid promotes albumin deposition in Purkinje cell, astrocytic activation and lipid peroxidation in fetal brain. Neuroscience 134(3):867–875
39. Monaghan DT, Beaton JA (1991) Quinolinate differentiates between forebrain and cerebellar NMDA receptors. Eur J Pharmacol 194(1):123–125
40. Wu W, Nicolazzo JA, Wen L, Chung R, Stankovic R, Bao SS, Lim CK, Brew BJ, Cullen KM, Guillemin GJ (2013) Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer’s disease brain. PLoS One 8(4):e59749