Quantification of Kras mutant fraction in the lung DNA of mice exposed to aerosolized particulate vanadium pentoxide by inhalation

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 789-790, Issue , 2015, Pages 53-60

  Banda, Malathi ^a   McKim, Karen L ^a   Haber, Lynne T ^b,e   MacGregor, Judith A ^c   Gollapudi, B Bhaskar ^d   Parsons, Barbara L ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Toxicology Excellence for Risk Assessment   (United States)

^c Toxicology Consulting Services   (United States)

^d EXPONENT INC   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Carcinogenesis; Mode of action; Mutation; Vanadium pentoxide

Indexed keywords

DNA; VANADIUM PENTOXIDE; AEROSOL; CODON; KRAS2 PROTEIN, MOUSE; PARTICULATE MATTER; PROTEIN P21; VANADIUM DERIVATIVE;

AEROSOL; AIRBORNE PARTICLE; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B6C3F1 MOUSE; CHEMICAL CARCINOGENESIS; CHEMICAL MUTAGENESIS; CODON; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GENE AMPLIFICATION; GENE MUTATION; INHALATION; LUNG ALVEOLUS CELL CARCINOMA; LUNG CARCINOGENESIS; MALE; MOUSE; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ADMINISTRATION AND DOSAGE; ANIMAL; CARCINOGENESIS; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; GENETICS; INHALATIONAL DRUG ADMINISTRATION; LUNG; LUNG TUMOR; METABOLISM; MUTAGEN TESTING; MUTATION; NUCLEOTIDE SEQUENCE; PARTICULATE MATTER; PATHOLOGY; PROCEDURES; TIME; TOXICITY; TRANSGENIC MOUSE;

MUS;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; CARCINOGENESIS; CODON; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; LUNG; LUNG NEOPLASMS; MALE; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTATION; PARTICULATE MATTER; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS P21(RAS); TIME FACTORS; VANADIUM COMPOUNDS;

EID: 84938202536     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2015.07.003     Document Type: Article

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