Identification of lipid droplet structure-like/resident proteins in Caenorhabditis elegans

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1853, Issue 10, 2015, Pages 2481-2491

  Na, Huimin ^a,b   Zhang, Peng ^a,b   Chen, Yong ^a   Zhu, Xiaotong ^a,b   Liu, Yi ^a   Liu, Yangli ^a,b   Xie, Kang ^a,b   Xu, Ningyi ^c,d   Yang, Fuquan ^a   Yu, Yong ^e   Cichello, Simon ^f   Mak, Ho Yi ^c,d   Wang, Meng C ^e   Zhang, Hong ^a   Liu, Pingsheng ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^d UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f LA TROBE UNIVERSITY   (Australia)

Author keywords

Lipid droplet; MDT 28; Perilipin family; Structure like Resident Proteins; Triacylglycerol (TAG)

Indexed keywords

FAT DROPLET; PROTEOME; TRIACYLGLYCEROL; CAENORHABDITIS ELEGANS PROTEIN;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; INTESTINE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TARGETING; ANIMAL; ANTIBODY SPECIFICITY; GENETICS; LIPID METABOLISM; METABOLISM; PHYSIOLOGY;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; LIPID METABOLISM; ORGAN SPECIFICITY; TRIGLYCERIDES;

EID: 84938152483     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2015.05.020     Document Type: Article

References (43)

1. Murphy D.J. The biogenesis and functions of lipid bodies in animals, plants and microorganisms. Prog. Lipid Res. 2001, 40:325-438.
2. Martin S., Parton R.G. Lipid droplets: a unified view of a dynamic organelle. Nat. Rev. Mol. Cell Biol. 2006, 7:373-378.
3. van Herpen N.A., Schrauwen-Hinderling V.B. Lipid accumulation in non-adipose tissue and lipotoxicity. Physiol. Behav. 2008, 94:231-241.
4. Farese R.V., Walther T.C. Lipid droplets finally get a little R-E-S-P-E-C-T. Cell 2009, 139:855-860.
5. Yang L., Ding Y., Chen Y., Zhang S., Huo C., Wang Y., Yu J., Zhang P., Na H., Zhang H., Ma Y., Liu P. The proteomics of lipid droplets: structure, dynamics, and functions of the organelle conserved from bacteria to humans. J. Lipid Res. 2012, 53:1245-1253.
6. Murphy D.J. The dynamic roles of intracellular lipid droplets: from archaea to mammals. Protoplasma 2012, 249:541-585.
7. Bartz R., Li W.H., Venables B., Zehmer J.K., Roth M.R., Welti R., Anderson R.G., Liu P., Chapman K.D. Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic. J. Lipid Res. 2007, 48:837-847.
8. Liu P., Ying Y., Zhao Y., Mundy D.I., Zhu M., Anderson R.G. Chinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane traffic. J. Biol. Chem. 2004, 279:3787-3792.
9. Greenberg A.S., Egan J.J., Wek S.A., Garty N.B., Blanchette-Mackie E.J., Londos C. Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. J. Biol. Chem. 1991, 266:11341-11346.
10. Jiang H.P., Serrero G. Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:7856-7860.
11. Brasaemle D.L., Barber T., Wolins N.E., Serrero G., Blanchette-Mackie E.J., Londos C. Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein. J. Lipid Res. 1997, 38:2249-2263.
12. Wolins N.E., Rubin B., Brasaemle D.L. TIP47 associates with lipid droplets. J. Biol. Chem. 2001, 276:5101-5108.
13. Wolins N.E., Skinner J.R., Schoenfish M.J., Tzekov A., Bensch K.G., Bickel P.E. Adipocyte protein S3-12 coats nascent lipid droplets. J. Biol. Chem. 2003, 278:37713-37721.
14. Wolins N.E., Quaynor B.K., Skinner J.R., Tzekov A., Croce M.A., Gropler M.C., Varma V., Yao-Borengasser A., Rasouli N., Kern P.A., Finck B.N., Bickel P.E. OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization. Diabetes 2006, 55:3418-3428.
15. Kimmel A.R., Brasaemle D.L., McAndrews-Hill M., Sztalryd C., Londos C. Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins. J. Lipid Res. 2010, 51:468-471.
16. Ozeki S., Cheng J., Tauchi-Sato K., Hatano N., Taniguchi H., Fujimoto T. Rab18 localizes to lipid droplets and induces their close apposition to the endoplasmic reticulum-derived membrane. J. Cell Sci. 2005, 118:2601-2611.
17. Martin S., Driessen K., Nixon S.J., Zerial M., Parton R.G. Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism. J. Biol. Chem. 2005, 280:42325-42335.
18. Liu P.S., Bartz R., Zehmer J.K., Ying Y.S., Zhu M., Serrero G., Anderson R.G.W. Rab-regulated interaction of early endosomes with lipid droplets. Biochim. Biophys. Acta, Mol. Cell Res. 2007, 1773:784-793.
19. Pu J., Ha C.W., Zhang S., Jung J.P., Huh W.K., Liu P. Interactomic study on interaction between lipid droplets and mitochondria. Protein Cell 2011, 2:487-496.
20. Binns D., Januszewski T., Chen Y., Hill J., Markin V.S., Zhao Y., Gilpin C., Chapman K.D., Anderson R.G., Goodman J.M. An intimate collaboration between peroxisomes and lipid bodies. J. Cell Biol. 2006, 173:719-731.
21. Zehmer J.K., Huang Y., Peng G., Pu J., Anderson R.G., Liu P. A role for lipid droplets in inter-membrane lipid traffic. Proteomics 2009, 9:914-921.
22. Kenyon C., Chang J., Gensch E., Rudner A., Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993, 366:461-464.
23. Brock T.J., Browse J., Watts J.L. Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans. Genetics 2007, 176:865-875.
24. Wang M.C., O'Rourke E.J., Ruvkun G. Fat metabolism links germline stem cells and longevity in C. elegans. Science 2008, 322:957-960.
25. Mak H.Y. Lipid droplets as fat storage organelles in Caenorhabditis elegans: thematic review series: lipid droplet synthesis and metabolism: from yeast to man. J. Lipid Res. 2012, 53:28-33.
26. McKay R.M., McKay J.P., Avery L., Graff J.M. C. elegans: a model for exploring the genetics of fat storage. Dev. Cell 2003, 4:131-142.
27. O'Rourke E.J., Soukas A.A., Carr C.E., Ruvkun G. C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metab. 2009, 10:430-435.
28. Wang M.C., Min W., Freudiger C.W., Ruvkun G., Xie X.S. RNAi screening for fat regulatory genes with SRS microscopy. Nat. Methods 2011, 8:135-138.
29. Zhang P., Na H., Liu Z., Zhang S., Xue P., Chen Y., Pu J., Peng G., Huang X., Yang F., Xie Z., Xu T., Xu P., Ou G., Zhang S.O., Liu P. Proteomic study and marker protein identification of Caenorhabditis elegans lipid droplets. Mol. Cell. Proteomics MCP 2012, 11:317-328.
30. Bartz R., Zehmer J.K., Zhu M., Chen Y., Serrero G., Zhao Y., Liu P. Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation. J. Proteome Res. 2007, 6:3256-3265.
31. Ding Y.F., Zhang S.Y., Yang L., Na H.M., Zhang P., Zhang H.N., Wang Y., Chen Y., Yu J.H., Huo C.X., Xu S.M., Garaiova M., Cong Y.S., Liu P.S. Isolating lipid droplets from multiple species. Nat. Protoc. 2013, 8:43-51.
32. Thorpe C.J., Schlesinger A., Carter J.C., Bowerman B. Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm. Cell 1997, 90:695-705.
33. Zhang H., Wang Y., Li J., Yu J., Pu J., Li L., Zhang H., Zhang S., Peng G., Yang F., Liu P. Proteome of skeletal muscle lipid droplet reveals association with mitochondria and apolipoprotein a-I. J. Proteome Res. 2011, 10:4757-4768.
34. Kuroyanagi H., Kobayashi T., Mitani S., Hagiwara M. Transgenic alternative-splicing reporters reveal tissue-specific expression profiles and regulation mechanisms in vivo. Nat. Methods 2006, 3:909-915.
35. Cassata G., Kagoshima H., Andachi Y., Kohara Y., Durrenberger M.B., Hall D.H., Burglin T.R. The LIM homeobox gene ceh-14 confers thermosensory function to the AFD neurons in Caenorhabditis elegans. Neuron 2000, 25:587-597.
36. Ashrafi K., Chang F.Y., Watts J.L., Fraser A.G., Kamath R.S., Ahringer J., Ruvkun G. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 2003, 421:268-272.
37. Hellerer T., Axang C., Brackmann C., Hillertz P., Pilon M., Enejder A. Monitoring of lipid storage in Caenorhabditis elegans using coherent anti-Stokes Raman scattering (CARS) microscopy. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:14658-14663.
38. Brasaemle D.L. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J. Lipid Res. 2007, 48:2547-2559.
39. Fujimoto Y., Itabe H., Sakai J., Makita M., Noda J., Mori M., Higashi Y., Kojima S., Takano T. Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7. Biochim. Biophys. Acta 2004, 1644:47-59.
40. Athenstaedt K., Zweytick D., Jandrositz A., Kohlwein S.D., Daum G. Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J. Bacteriol. 1999, 181:6441-6448.
41. Bouchoux J., Beilstein F., Pauquai T., Guerrera I.C., Chateau D., Ly N., Alqub M., Klein C., Chambaz J., Rousset M., Lacorte J.M., Morel E., Demignot S. The proteome of cytosolic lipid droplets isolated from differentiated Caco-2/TC7 enterocytes reveals cell-specific characteristics. Biol. Cell. 2011, 103:499-517.
42. Beilstein F., Bouchoux J., Rousset M., Demignot S. Proteomic analysis of lipid droplets from Caco-2/TC7 enterocytes identifies novel modulators of lipid secretion. PLoS One 2013, 8:e53017.
43. Su W., Wang Y., Jia X., Wu W., Li L., Tian X., Li S., Wang C., Xu H., Cao J., Han Q., Xu S., Chen Y., Zhong Y., Zhang X., Liu P., Gustafsson J.A., Guan Y. Comparative proteomic study reveals 17beta-HSD13 as a pathogenic protein in nonalcoholic fatty liver disease. Proc. Natl. Acad. Sci. U. S. A. 2014, 111:11437-11442.