Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1853, Issue 10, 2015, Pages 2361-2370

  Katayama, Kazuhiro ^a   Kapoor, Khyati ^a   Ohnuma, Shinobu ^a   Patel, Atish ^a   Swaim, William ^b   Ambudkar, Indu S ^b   Ambudkar, Suresh V ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Degradation; Endosome; Half life; Lysosome; P glycoprotein; Proteasome

Indexed keywords

BAFILOMYCIN A1; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CELL SURFACE PROTEIN; LACTACYSTIN; MULTIDRUG RESISTANCE PROTEIN 1; RHODAMINE 123; ABCB1 PROTEIN, HUMAN; ANTIFUNGAL AGENT; MACROLIDE; MULTIDRUG RESISTANCE PROTEIN; PROTEASOME INHIBITOR;

ARTICLE; BIOTINYLATION; CELL FATE; CELL SURFACE; COLORECTAL CANCER; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYSOSOME; MTT ASSAY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; WESTERN BLOTTING; GENETICS; METABOLISM; TUMOR CELL LINE;

ANTIFUNGAL AGENTS; CELL LINE, TUMOR; HUMANS; LYSOSOMES; MACROLIDES; P-GLYCOPROTEINS; PROTEASOME INHIBITORS; PROTEOLYSIS;

EID: 84938125626     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2015.06.001     Document Type: Article

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