Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death

Journal of Investigative Dermatology

Volumn 135, Issue 6, 2015, Pages 1629-1637

  Armstrong, Jane L ^a,b   Hill, David S ^a   McKee, Christopher S ^a   Hernandez Tiedra, Sonia ^c   Lorente, Mar ^c   Lopez Valero, Israel ^c,d   Anagnostou, Maria Eleni ^a   Babatunde, Fiyinfoluwa ^a   Corazzari, Marco ^e   Redfern, Christopher P F ^f   Velasco, Guillermo ^c,d   Lovat, Penny E ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF SUNDERLAND   (United Kingdom)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

^f NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; BECLIN 1; CANNABIDIOL; CASPASE 3; CHLOROQUINE; DRONABINOL; NABIXIMOLS; SMALL INTERFERING RNA; TEMOZOLOMIDE; AMBRA1 PROTEIN, HUMAN; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; BRAF PROTEIN, HUMAN; CANNABINOID; CANNABINOL; DACARBAZINE; MEMBRANE PROTEIN; PLANT EXTRACT; RAS PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TETRAHYDROCANNABINOL-CANNABIDIOL COMBINATION;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL ACTIVATION; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR XENOGRAFT; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; CANCER TRANSPLANTATION; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; HUMAN; MALE; MELANOMA; METABOLISM; METASTASIS; NEOPLASM; NUDE MOUSE; PATHOLOGY; SKIN TUMOR; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CANNABINOIDS; CANNABINOL; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DACARBAZINE; DRONABINOL; HUMANS; MALE; MELANOMA; MEMBRANE PROTEINS; MICE; MICE, NUDE; MICROSCOPY, CONFOCAL; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NEOPLASMS; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS B-RAF; RAS PROTEINS; SKIN NEOPLASMS;

EID: 84938096558     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2015.45     Document Type: Article

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