-
1
-
-
0037214337
-
Early thickening of the reticular basement membrane in children with difficult asthma
-
Payne DN, Rogers AV, Adelroth E, Bandi V., Guntupalli KK, Bush A, et al. Early thickening of the reticular basement membrane in children with difficult asthma. Am J Resp Crit Care Med. 2003;167:78-82.
-
(2003)
Am J Resp Crit Care Med.
, vol.167
, pp. 78-82
-
-
Payne, D.N.1
Rogers, A.V.2
Adelroth, E.3
Bandi, V.4
Guntupalli, K.K.5
Bush, A.6
-
2
-
-
33747756534
-
Asthma: Defining of the persistent adult phenotypes
-
Wenzel SE. Asthma: defining of the persistent adult phenotypes. Lancet. 2006;368(9537):804-13.
-
(2006)
Lancet
, vol.368
, Issue.9537
, pp. 804-813
-
-
Wenzel, S.E.1
-
3
-
-
33645101537
-
Inflammatory subtypes in asthma: Assessment and identification using induced sputum
-
Simpson JL, Scott R, Boyle M.J., Gibson PG. Inflammatory subtypes in asthma: assessment and identification using induced sputum. Respirology. 2006;11:54-61.
-
(2006)
Respirology
, vol.11
, pp. 54-61
-
-
Simpson, J.L.1
Scott, R.2
Boyle, M.J.3
Gibson, P.G.4
-
4
-
-
69249150516
-
T-helper type2-driven inflammation defines major subphenotypes of asthma
-
Woodruff PG, Modrek B, Choy D.F., Jia G., Abbas AR, Ellwanger A, et al. T-helper type2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med. 2009;180:388-95.
-
(2009)
Am J Respir Crit Care Med.
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
Jia, G.4
Abbas, A.R.5
Ellwanger, A.6
-
5
-
-
84892365749
-
Adult asthma biomarkers
-
Kim MA, Shin YS, le Pham D, Park HS. Adult asthma biomarkers. Curr Opin Allergy Clin Immunol. 2014;14(1):49-54.
-
(2014)
Curr Opin Allergy Clin Immunol.
, vol.14
, Issue.1
, pp. 49-54
-
-
Kim, M.A.1
Shin, Y.S.2
Le Pham, D.3
Park, H.S.4
-
6
-
-
78649673636
-
Efficacy and safety of subcutaneous Omalizumab vs placebo as add-on therapy to corticosteroids for children and adults with asthma: A systematic review
-
Rodrigo GJ, Neffen H, Castro-Rodriguez JA. Efficacy and safety of subcutaneous omalizumab vs placebo as add-on therapy to corticosteroids for children and adults with asthma: a systematic review. Chest. 2011;139(1):28-35.
-
(2011)
Chest.
, vol.139
, Issue.1
, pp. 28-35
-
-
Rodrigo, G.J.1
Neffen, H.2
Castro-Rodriguez, J.A.3
-
7
-
-
67650938578
-
Relationship between Omalizumab pharmacokinetics, IgE pharmacodynamics and symptoms in patients with severe persistent allergic (IgE-mediated) asthma
-
Lowe PJ, Tannenbaum S, Gautier A., Jimenez P. Relationship between omalizumab pharmacokinetics, IgE pharmacodynamics and symptoms in patients with severe persistent allergic (IgE-mediated) asthma. Br J Clin Pharmacol. 2009;68:61-76.
-
(2009)
Br J Clin Pharmacol.
, vol.68
, pp. 61-76
-
-
Lowe, P.J.1
Tannenbaum, S.2
Gautier, A.3
Jimenez, P.4
-
8
-
-
84876883293
-
Exploring the effects of Omalizumab in allergic asthma: An analysis of biomarkers in the EXTRA study
-
Hanania NA, Wenzel S, Rosén K, Hsieh H.J., Mosesova S., Choy DF, et al. Exploring the effects of omalizumab in allergic asthma: an analysis of biomarkers in the EXTRA study. Am J Respir Crit Care Med. 2013;187(8):804-11.
-
(2013)
Am J Respir Crit Care Med.
, vol.187
, Issue.8
, pp. 804-811
-
-
Hanania, N.A.1
Wenzel, S.2
Rosén, K.3
Hsieh, H.J.4
Mosesova, S.5
Choy, D.F.6
-
10
-
-
80052268492
-
Long-term benefits of Omalizumab in a patient with severe non-allergic asthma
-
Menzella F, Piro R, Facciolongo N., Castagnetti C, Simonazzi A, Zucchi L. Long-term benefits of omalizumab in a patient with severe non-allergic asthma. Allergy Asthma Clin Immunol. 2011;7(1):9.
-
(2011)
Allergy Asthma Clin Immunol.
, vol.7
, Issue.1
, pp. 9
-
-
Menzella, F.1
Piro, R.2
Facciolongo, N.3
Castagnetti, C.4
Simonazzi, A.5
Zucchi, L.6
-
11
-
-
77957928078
-
Local production of IgE in the respiratory mucosa and the concept of entopy: Does allergy exist in nonallergic rhinitis?
-
Forester JP, Calabria CW Local production of IgE in the respiratory mucosa and the concept of entopy: does allergy exist in nonallergic rhinitis? Ann Allergy Asthma Immunol. 2010;105(4):249-55
-
(2010)
Ann Allergy Asthma Immunol
, vol.105
, Issue.4
, pp. 249-255
-
-
Forester, J.P.1
Calabria, C.W.2
-
12
-
-
79952795093
-
Randomized trial of Omalizumab (anti-ige) for asthma in inner-city children
-
Busse WW, Morgan WJ, Gergen P.J., Mitchell HE, Gern JE, Liu AH, et al Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. N Engl J Med. 2011;364:1005-15.
-
(2011)
N Engl J Med.
, vol.364
, pp. 1005-1015
-
-
Busse, W.W.1
Morgan, W.J.2
Gergen, P.J.3
Mitchell, H.E.4
Gern, J.E.5
Liu, A.H.6
-
13
-
-
77956584475
-
Comorbidities of asthma during childhood: Possibly important, yet poorly studied
-
de Groot E.P., Duiverman EJ, Brand PL Comorbidities of asthma during childhood: possibly important, yet poorly studied. Eur Respir J. 2010;36:671-8.
-
(2010)
Eur Respir J.
, vol.36
, pp. 671-678
-
-
De Groot, E.P.1
Duiverman, E.J.2
Brand, P.L.3
-
14
-
-
69949123296
-
Off-label use of Omalizumab in non-asthma conditions: New opportunities
-
Morjaria JB, Polosa R. Off-label use of omalizumab in non-asthma conditions: new opportunities. Expert Rev Respir Med. 2009;3:299-308.
-
(2009)
Expert Rev Respir Med.
, vol.3
, pp. 299-308
-
-
Morjaria, J.B.1
Polosa, R.2
-
15
-
-
43649108517
-
One year administration of anti-ige to a patient with churg-strauss syndrome
-
Giavina-Bianchi P., Agondi R, Kalil J. One year administration of anti-IgE to a patient with Churg-Strauss syndrome. Int Arch Allergy Immunol 2008;146(2):176.
-
(2008)
Int Arch Allergy Immunol
, vol.146
, Issue.2
, pp. 176
-
-
Giavina-Bianchi, P.1
Agondi, R.2
Kalil, J.3
-
16
-
-
46049101600
-
Omalizumab and churg-strauss syndrome
-
Giavina-Bianchi P., Giavina-Bianchi M, Agondi R., Kalil J. Omalizumab and Churg-Strauss syndrome. J Allergy Clin Immunol. 2008;122(1):217.
-
(2008)
J Allergy Clin Immunol.
, vol.122
, Issue.1
, pp. 217
-
-
Giavina-Bianchi, P.1
Giavina-Bianchi, M.2
Agondi, R.3
Kalil, J.4
-
17
-
-
84864819156
-
Omalizumab as a steroid-sparing agent in chronic eosinophilic pneumonia
-
Kaya H, Gümüj S, Uçar E, Aydoʇan M, Mujabak U, Tozkoparan E, et al. Omalizumab as a steroid-sparing agent in chronic eosinophilic pneumonia Chest. 2012;142(2):513-6
-
(2012)
Chest
, vol.142
, Issue.2
, pp. 513-516
-
-
Kaya, H.1
Gümüj, S.2
Uçar, E.3
Aydoʇan, M.4
Mujabak, U.5
Tozkoparan, E.6
-
18
-
-
17744376022
-
Anti-immunoglobulin E treatment with Omalizumab in allergic diseases: An update on anti-inflammatory activity and clinical efficacy
-
Holgate ST, Djukanović R, Casale T, Bousquet J. Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy. Clin Exp Allergy. 2005;35(4):408-16.
-
(2005)
Clin Exp Allergy.
, vol.35
, Issue.4
, pp. 408-416
-
-
Holgate, S.T.1
Djukanović, R.2
Casale, T.3
Bousquet, J.4
-
19
-
-
72049131312
-
After 6 years with xolair; a 3-year withdrawal follow-up
-
Nopp A, Johansson SG, Adédoyin J, Ankerst J., Palmqvist M, Oman H. After 6 years with Xolair; a 3-year withdrawal follow-up. Allergy. 2010;65(1):56-60
-
(2010)
Allergy.
, vol.65
, Issue.1
, pp. 56-60
-
-
Nopp, A.1
Johansson, S.G.2
Adédoyin, J.3
Ankerst, J.4
Palmqvist, M.5
Oman, H.6
-
20
-
-
79955058809
-
Clinical benefits of 7 years of treatment with Omalizumab in severe uncontrolled asthmatics
-
Pace E, Ferraro M, Bruno A., Chiappara G, Bousquet J, Giomarkaj M. Clinical benefits of 7 years of treatment with omalizumab in severe uncontrolled asthmatics. J Asthma. 2011;48(4):387-92.
-
(2011)
J Asthma
, vol.48
, Issue.4
, pp. 387-392
-
-
Pace, E.1
Ferraro, M.2
Bruno, A.3
Chiappara, G.4
Bousquet, J.5
Giomarkaj, M.6
-
21
-
-
84859358781
-
Clinical and pharmacoeconomic aspects of Omalizumab: A 4-year follow-up
-
Menzella F, Facciolongo N, Piro R., Formisano D, Roggeri A, Simonazzi A., et al. Clinical and pharmacoeconomic aspects of omalizumab: a 4-year follow-up. Ther Adv Respir Dis. 2012;6(2):87-95.
-
(2012)
Ther Adv Respir Dis.
, vol.6
, Issue.2
, pp. 87-95
-
-
Menzella, F.1
Facciolongo, N.2
Piro, R.3
Formisano, D.4
Roggeri, A.5
Simonazzi, A.6
-
22
-
-
79954503591
-
Cost-utility of add-on Omalizumab in difficult-to-treat allergic asthma in Italy
-
Dal Negro R.W., Pradelli L, Tognella S., Micheletto C, Iannazzo S. Cost-utility of add-on omalizumab in difficult-to-treat allergic asthma in Italy. Eur Ann Allergy Clin Immunol. 2011;43(2):45-53
-
(2011)
Eur Ann Allergy Clin Immunol.
, vol.43
, Issue.2
, pp. 45-53
-
-
Dal Negro, R.W.1
Pradelli, L.2
Tognella, S.3
Micheletto, C.4
Iannazzo, S.5
-
23
-
-
84861596408
-
Monoclonal antibodies for chronic refractory asthma and pipeline developments
-
Polosa R, Casale T. Monoclonal antibodies for chronic refractory asthma and pipeline developments. Drug Discovery Today. 2013;17:591-9.
-
(2013)
Drug Discovery Today.
, vol.17
, pp. 591-599
-
-
Polosa, R.1
Casale, T.2
-
24
-
-
34547691135
-
Phase 1 study of lumiliximab with detailed pharmacokinetic and pharmacodynamic measurements in patients with relapsed or refractory chronic lymphocytic leukemia
-
Byrd JC, O'Brien S, Flinn IW, Kipps T.J., Weiss M., Rai K, et al. Phase 1 study of lumiliximab with detailed pharmacokinetic and pharmacodynamic measurements in patients with relapsed or refractory chronic lymphocytic leukemia. Clin Cancer Res. 2007;13:4448-55.
-
(2007)
Clin Cancer Res.
, vol.13
, pp. 4448-4455
-
-
Byrd, J.C.1
O'Brien, S.2
Flinn, I.W.3
Kipps, T.J.4
Weiss, M.5
Rai, K.6
-
25
-
-
0142250482
-
Regulatory T, cells under scrutiny
-
Bach JF. Regulatory T, cells under scrutiny. Nat Rev Immunol. 2003;3(3):189-98.
-
(2003)
Nat Rev Immunol.
, vol.3
, Issue.3
, pp. 189-198
-
-
Bach, J.F.1
-
26
-
-
80052259648
-
Making sense of regulatory T cell suppressive function
-
Shalev I, Schmelzle M, Robson S.C., Levy G. Making sense of regulatory T cell suppressive function. Semin Immunol. 2011;23(4):282-92.
-
(2011)
Semin Immunol.
, vol.23
, Issue.4
, pp. 282-292
-
-
Shalev, I.1
Schmelzle, M.2
Robson, S.C.3
Levy, G.4
-
27
-
-
57349179165
-
Daclizumab improves asthma control in patients with moderate to severe persistent asthma: A randomized, controlled trial
-
Busse WW, Israel E, Nelson H.S., Baker JW, Charous BL, Young DY, et al Daclizumab improves asthma control in patients with moderate to severe persistent asthma: a randomized, controlled trial. Am J Respir Crit Care Med. 2008;178(10):1002-8.
-
(2008)
Am J Respir Crit Care Med.
, vol.178
, Issue.10
, pp. 1002-1008
-
-
Busse, W.W.1
Israel, E.2
Nelson, H.S.3
Baker, J.W.4
Charous, B.L.5
Young, D.Y.6
-
28
-
-
79954583416
-
Effects of interleukin-13 blockade on allergen-induced airway responses in mild atopic asthma
-
Gauvreau GM, Boulet LP, Cockcroft D.W., Fitzgerald JM, Carlsten C, Davis BE, et al Effects of interleukin-13 blockade on allergen-induced airway responses in mild atopic asthma. Am J Respir Crit Care Med. 2011; 183(8):1007-14
-
(2011)
Am J Respir Crit Care Med.
, vol.183
, Issue.8
, pp. 1007-1014
-
-
Gauvreau, G.M.1
Boulet, L.P.2
Cockcroft, D.W.3
Fitzgerald, J.M.4
Carlsten, C.5
Davis, B.E.6
-
29
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
Corren J, Lemanske RF, Hanania N.A., Korenblat PE, Parsey MV, Arron JR, et al Lebrikizumab treatment in adults with asthma. N Engl J Med 2011;365(12):1088-98.
-
(2011)
N Engl J Med
, vol.365
, Issue.12
, pp. 1088-1098
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
Korenblat, P.E.4
Parsey, M.V.5
Arron, J.R.6
-
30
-
-
84861889921
-
Eosinophil development, regulation of eosinophil-specific genes, and role of eosinophils in the pathogenesis of asthma
-
Uhm TG, Kim BS, Chung IY Eosinophil development, regulation of eosinophil-specific genes, and role of eosinophils in the pathogenesis of asthma. Allergy Asthma Immunol Res. 2012;4(2):68-79.
-
(2012)
Allergy Asthma Immunol Res.
, vol.4
, Issue.2
, pp. 68-79
-
-
Uhm, T.G.1
Kim, B.S.2
Chung, I.Y.3
-
31
-
-
70450175479
-
IL-5- and eosinophil-mediated inflammation: From discovery to therapy
-
Kouro T, Takatsu K IL-5- and eosinophil-mediated inflammation: from discovery to therapy. Int Immunol. 2009 21(12):1303-9.
-
(2009)
Int Immunol.
, vol.21
, Issue.12
, pp. 1303-1309
-
-
Kouro, T.1
Takatsu, K.2
-
32
-
-
3042714189
-
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice
-
Tanaka H, Komai M, Nagao K., Ishizaki M, Kajiwara D, Takatsu K., et al. Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice. Am J Respir Cell Mol Biol. 200431(1):62-8.
-
(2004)
Am J Respir Cell Mol Biol.
, vol.31
, Issue.1
, pp. 62-68
-
-
Tanaka, H.1
Komai, M.2
Nagao, K.3
Ishizaki, M.4
Kajiwara, D.5
Takatsu, K.6
-
33
-
-
40949146020
-
Treatment of patients with the hypereosinophilic syndrome with mepolizumab
-
2008358
-
Rothenberg ME, Klion AD, Roufosse F.E., Kahn JE, Weller PF, Simon HU, et al Treatment of patients with the hypereosinophilic syndrome with mepolizumab. N Engl J Med. 2008358(12):1215-28.
-
N Engl J Med.
, Issue.12
, pp. 1215-1228
-
-
Rothenberg, M.E.1
Klion, A.D.2
Roufosse, F.E.3
Kahn, J.E.4
Weller, P.F.5
Simon, H.U.6
-
34
-
-
77952737931
-
Mepolizumab as a steroid-sparing treatment option in patients with churg-strauss syndrome
-
Kim S, Marigowda G, Oren E., Israel E, Wechsler ME. Mepolizumab as a steroid-sparing treatment option in patients with Churg-Strauss syndrome. J Allergy Clin Immunol. 2010;125(6):1336-43
-
(2010)
J Allergy Clin Immunol.
, vol.125
, Issue.6
, pp. 1336-1343
-
-
Kim, S.1
Marigowda, G.2
Oren, E.3
Israel, E.4
Wechsler, M.E.5
-
35
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar P, Brightling CE, Hargadon B, Gupta S., Monteiro W, Sousa A, et al Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med. 2009;360(10):973-84.
-
(2009)
N Engl J Med.
, vol.360
, Issue.10
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
Gupta, S.4
Monteiro, W.5
Sousa, A.6
-
36
-
-
84865145614
-
Mepolizumab for severe eosinophilic asthma (DREAM): A multicentre, double-blind, placebo-controlled trial
-
Pavord ID, Korn S, Howarth P., Bleecker ER, Buhl R, Keene ON, et al Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial. Lancet. 2012;380(9842):651-9.
-
(2012)
Lancet
, vol.380
, Issue.9842
, pp. 651-659
-
-
Pavord, I.D.1
Korn, S.2
Howarth, P.3
Bleecker, E.R.4
Buhl, R.5
Keene, O.N.6
-
37
-
-
81455138227
-
Reslizumab and eosinophilic asthma: One step closer to phenotype-directed therapy?
-
McCallister JW. Reslizumab and eosinophilic asthma: one step closer to phenotype-directed therapy? Am J Respir Crit Care Med. 2011;184(10):1096-7.
-
(2011)
Am J Respir Crit Care Med.
, vol.184
, Issue.10
, pp. 1096-1097
-
-
McCallister, J.W.1
-
38
-
-
84907423833
-
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma
-
Bel EH, Wenzel SE, Thompson P.J., Prazma CM, Keene ON, Yancey SW, et al Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med. 2014;371:1189-97.
-
(2014)
N Engl J Med.
, vol.371
, pp. 1189-1197
-
-
Bel, E.H.1
Wenzel, S.E.2
Thompson, P.J.3
Prazma, C.M.4
Keene, O.N.5
Yancey, S.W.6
-
39
-
-
84907424177
-
Mepolizumab treatment in patients with severe eosinophilic asthma
-
Ortega HG, Liu MC, Pavord I.D., Brusselle GG, FitzGerald JM, Chetta A, et al Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med. 2014;371(13):1198-207.
-
(2014)
N Engl J Med.
, vol.371
, Issue.13
, pp. 1198-1207
-
-
Ortega, H.G.1
Liu, M.C.2
Pavord, I.D.3
Brusselle, G.G.4
FitzGerald, J.M.5
Chetta, A.6
-
40
-
-
81455155725
-
Reslizumab for poorly controlled, eosinophilic asthma: A randomized, placebo-controlled study
-
Castro M, Mathur S, Hargreave F., Boulet LP, Xie F, Young J, et al Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med. 2011;184(10):1125-32.
-
(2011)
Am J Respir Crit Care Med.
, vol.184
, Issue.10
, pp. 1125-1132
-
-
Castro, M.1
Mathur, S.2
Hargreave, F.3
Boulet, L.P.4
Xie, F.5
Young, J.6
-
41
-
-
77952683218
-
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma
-
Busse WW, Katial R, Gossage D., Sari S, Wang B, Kolbeck R., et al. Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma. J Allergy Clin Immunol. 2010;125(6):1237-44.
-
(2010)
J Allergy Clin Immunol.
, vol.125
, Issue.6
, pp. 1237-1244
-
-
Busse, W.W.1
Katial, R.2
Gossage, D.3
Sari, S.4
Wang, B.5
Kolbeck, R.6
-
42
-
-
77952733788
-
MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
-
Kolbeck R, Kozhich A, Koike M., Peng L, Andersson CK, Damschroder M.M., et al. MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function. J Allergy Clin Immunol. 2010;125(6):1344-53.
-
(2010)
J Allergy Clin Immunol.
, vol.125
, Issue.6
, pp. 1344-1353
-
-
Kolbeck, R.1
Kozhich, A.2
Koike, M.3
Peng, L.4
Andersson, C.K.5
Damschroder, M.M.6
-
43
-
-
42949132127
-
Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses
-
Gauvreau GM, Boulet LP, Cockcroft D.W., Baatjes A., Cote J, Deschesnes F, et al Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses. Am J Respir Crit Care Med. 2008;177(9):952-8.
-
(2008)
Am J Respir Crit Care Med.
, vol.177
, Issue.9
, pp. 952-958
-
-
Gauvreau, G.M.1
Boulet, L.P.2
Cockcroft, D.W.3
Baatjes, A.4
Cote, J.5
Deschesnes, F.6
-
44
-
-
84862126172
-
Mogamulizumab: First global approval
-
Subramaniam JM, Whiteside G, McKeage K., Croxtall JC. Mogamulizumab: first global approval. Drugs. 2012;72(9):1293-8.
-
(2012)
Drugs.
, vol.72
, Issue.9
, pp. 1293-1298
-
-
Subramaniam, J.M.1
Whiteside, G.2
McKeage, K.3
Croxtall, J.C.4
-
45
-
-
0027361432
-
Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
-
Knight DM, Trinh H, Le J., Siegel S, Shealy D, McDonough M., et al. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody. Mol Immunol. 1993;30(16):1443-53.
-
(1993)
Mol Immunol.
, vol.30
, Issue.16
, pp. 1443-1453
-
-
Knight, D.M.1
Trinh, H.2
Le, J.3
Siegel, S.4
Shealy, D.5
McDonough, M.6
-
46
-
-
28244479315
-
Tumour necrosis factor (TNF-α) as a novel therapeutic target in symptomatic corticosteroid dependent asthma
-
Howarth PH, Babu KS, Arshad H.S., Lau L., Buckley M, McConnell W, et al Tumour necrosis factor (TNF-α) as a novel therapeutic target in symptomatic corticosteroid dependent asthma. Thorax. 2005;60(12):1012-8.
-
(2005)
Thorax.
, vol.60
, Issue.12
, pp. 1012-1018
-
-
Howarth, P.H.1
Babu, K.S.2
Arshad, H.S.3
Lau, L.4
Buckley, M.5
McConnell, W.6
-
47
-
-
79957987328
-
Efficacy and safety of etanercept in moderate-to-severe asthma: A randomised, controlled trial
-
Holgate ST, Noonan M, Chanez P., Busse W, Dupont L, Pavord I., et al. Efficacy and safety of etanercept in moderate-to-severe asthma: a randomised, controlled trial. Eur Respir J. 2011;37(6):1352-9.
-
(2011)
Eur Respir J.
, vol.37
, Issue.6
, pp. 1352-1359
-
-
Holgate, S.T.1
Noonan, M.2
Chanez, P.3
Busse, W.4
Dupont, L.5
Pavord, I.6
-
48
-
-
47049130758
-
The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory asthma: A double blind, randomised, placebo controlled trial
-
Morjaria JB, Chauhan AJ, Babu K.S., Davies DE, Holgate ST. The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial. Thorax. 2008;63(7):584-91.
-
(2008)
Thorax.
, vol.63
, Issue.7
, pp. 584-591
-
-
Morjaria, J.B.1
Chauhan, A.J.2
Babu, K.S.3
Davies, D.E.4
Holgate, S.T.5
-
49
-
-
84879127204
-
Monoclonal anti-TNF-α antibodies for severe steroid-dependent asthma: A case series
-
Taillé C, Poulet C, Marchand-Adam S, Borie R, Dombret MC, Crestani B, et al. Monoclonal anti-TNF-α antibodies for severe steroid-dependent asthma: a case series. Open Respir Med J. 2013;7:21-5.
-
(2013)
Open Respir Med J.
, vol.7
, pp. 21-25
-
-
Taillé, C.1
Poulet, C.2
Marchand-Adam, S.3
Borie, R.4
Dombret, M.C.5
Crestani, B.6
-
50
-
-
33749438560
-
The effects of a monoclonal antibody directed against tumor necrosis factor in asthma
-
Erin EM, Leaker BR, Nicholson G.C., Tan AJ, Green LM, Neighbour H, et al The effects of a monoclonal antibody directed against tumor necrosis factor in asthma. Am J Respir Crit Care Med. 2006;174(7):753-62.
-
(2006)
Am J Respir Crit Care Med.
, vol.174
, Issue.7
, pp. 753-762
-
-
Erin, E.M.1
Leaker, B.R.2
Nicholson, G.C.3
Tan, A.J.4
Green, L.M.5
Neighbour, H.6
-
51
-
-
62549084077
-
A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma
-
Wenzel SE, Barnes PJ, Bleecker E.R., Bousquet J., Busse W, Dahlén SE, et al. A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med. 2009;179(7):549-58.
-
(2009)
Am J Respir Crit Care Med.
, vol.179
, Issue.7
, pp. 549-558
-
-
Wenzel, S.E.1
Barnes, P.J.2
Bleecker, E.R.3
Bousquet, J.4
Busse, W.5
Dahlén, S.E.6
-
53
-
-
38049057089
-
TNF-α antagonists and the prevention of hospitalisation for chronic obstructive pulmonary disease
-
Suissa S, Ernst P, Hudson M. TNF-α antagonists and the prevention of hospitalisation for chronic obstructive pulmonary disease. Pulm Pharmacol Ther. 2008;21:234-8.
-
(2008)
Pulm Pharmacol Ther.
, vol.21
, pp. 234-238
-
-
Suissa, S.1
Ernst, P.2
Hudson, M.3
-
54
-
-
0036726535
-
What are the risks of biologic therapy in rheumatoid arthritis? An update on safety
-
Weisman MH. What are the risks of biologic therapy in rheumatoid arthritis? An update on safety. J Rheumatol. 2002; 65(Suppl):33-8.
-
(2002)
J Rheumatol.
, vol.65
, pp. 33-38
-
-
Weisman, M.H.1
-
55
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and Malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
-
Bongartz T, Sutton AJ, Sweeting M.J., Buchan I., Matteson EL, Montori V. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA. 2006;295:2275-85.
-
(2006)
JAMA
, vol.295
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Buchan, I.4
Matteson, E.L.5
Montori, V.6
-
56
-
-
84863376582
-
Eculizumab for treatment of asthma
-
Smith SG, Watson B, Clark G., Gauvreau GM. Eculizumab for treatment of asthma. Expert Opin Biol Ther. 2012;12(4):529-37.
-
(2012)
Expert Opin Biol Ther.
, vol.12
, Issue.4
, pp. 529-537
-
-
Smith, S.G.1
Watson, B.2
Clark, G.3
Gauvreau, G.M.4
-
57
-
-
0036398446
-
The il-1 family and inflammatory diseases
-
Dinarello CA. The Il-1 family and inflammatory diseases. Clin Exp Rheumatol. 2002;20(27):S1-S13.
-
(2002)
Clin Exp Rheumatol.
, vol.20
, Issue.27
, pp. S1-S13
-
-
Dinarello, C.A.1
-
59
-
-
77953680635
-
A monoclonal antibody to IL-1β attenuates the late asthmatic response to antigen challenge in patients with mild asthma
-
752
-
Pascoe S, Kanniess F, Bonner J., Lloyd P, Lowe P, Beier J., et al. A monoclonal antibody to IL-1β attenuates the late asthmatic response to antigen challenge in patients with mild asthma. Annu Congr Eur Resp Soc. 2006. Abs 752.
-
(2006)
Annu Congr Eur Resp Soc.
-
-
Pascoe, S.1
Kanniess, F.2
Bonner, J.3
Lloyd, P.4
Lowe, P.5
Beier, J.6
-
61
-
-
77952695527
-
The role of viruses in acute exacerbations of asthma
-
Jackson DJ, Johnston SL The role of viruses in acute exacerbations of asthma. J Allergy Clin Immunol. 2010;125:1178-87.
-
(2010)
J Allergy Clin Immunol.
, vol.125
, pp. 1178-1187
-
-
Jackson, D.J.1
Johnston, S.L.2
-
62
-
-
17144403499
-
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus
-
Wark PA, Johnston SL, Bucchieri F, Powell R., Puddicombe S, Laza-Stanca V, et al. Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus. J Exp Med. 2005;201:937-47.
-
(2005)
J Exp Med.
, vol.201
, pp. 937-947
-
-
Wark, P.A.1
Johnston, S.L.2
Bucchieri, F.3
Powell, R.4
Puddicombe, S.5
Laza-Stanca, V.6
-
63
-
-
84906932841
-
The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial
-
Djukanović R, Harrison T, Johnston SL, Gabbay F, Wark P, Thomson NC, et al. The effect of inhaled IFN-β on worsening of asthma symptoms caused by viral infections. A randomized trial. Am J Respir Crit Care Med. 2014;190(2):145-54.
-
(2014)
Am J Respir Crit Care Med.
, vol.190
, Issue.2
, pp. 145-154
-
-
Djukanović, R.1
Harrison, T.2
Johnston, S.L.3
Gabbay, F.4
Wark, P.5
Thomson, N.C.6
|