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Volumn 786-788, Issue , 2015, Pages 104-113

In vivo comet assay of acrylonitrile, 9-aminoacridine hydrochloride monohydrate and ethanol in rats

Author keywords

9 Aminoacridine hydrochloride monohydrate; Acrylonitrile; Ethanol; In vivo rat comet assay; JaCVAM validation study

Indexed keywords

9 AMINOACRIDINE HYDROCHLORIDE MONOHYDRATE; ACRYLONITRILE; ALCOHOL; AMINOACRIDINE; CARCINOGEN; CHLORIDE; UNCLASSIFIED DRUG;

EID: 84937977895     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2015.04.001     Document Type: Article
Times cited : (6)

References (28)
  • 1
    • 84875700070 scopus 로고    scopus 로고
    • Guidance on genotoxicity testing and data interpretation for pharmaceuticals intended for human use S2(R1) step 4 version
    • ICH harmonized tripartite guideline, Guidance on genotoxicity testing and data interpretation for pharmaceuticals intended for human use S2(R1) step 4 version, (2011).
    • (2011)
  • 6
    • 0002987035 scopus 로고
    • The single cell gel/comet assay: a microgel electrophoretic technique for the detection of DNA damage and repair in individual cells
    • Bios Scientific Publisher, Oxford, UK, D.H. Phillips, S. Venitt (Eds.)
    • Tice R.R. The single cell gel/comet assay: a microgel electrophoretic technique for the detection of DNA damage and repair in individual cells. Environ. Mutagen. 1995, 315-319. Bios Scientific Publisher, Oxford, UK. D.H. Phillips, S. Venitt (Eds.).
    • (1995) Environ. Mutagen. , pp. 315-319
    • Tice, R.R.1
  • 8
    • 0033670360 scopus 로고    scopus 로고
    • The comet assay with multiple mouse organs: comparison of Comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP carcinogenicity database
    • Sasaki Y.F., Sekihashi K., Izumiyama F., Nishidate E., Saga A., Ishida K., Tsuda S. The comet assay with multiple mouse organs: comparison of Comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP carcinogenicity database. Crit. Rev. Toxicol. 2000, 30:629-799.
    • (2000) Crit. Rev. Toxicol. , vol.30 , pp. 629-799
    • Sasaki, Y.F.1    Sekihashi, K.2    Izumiyama, F.3    Nishidate, E.4    Saga, A.5    Ishida, K.6    Tsuda, S.7
  • 10
    • 84937982702 scopus 로고    scopus 로고
    • re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide
    • IARC monographs on the evaluation of carcinogenic risks to humans: re-evaluation of some organic chemicals, hydrazine and hydrogen peroxide, 71 (1999).
    • (1999) , vol.71
  • 11
    • 0018900385 scopus 로고
    • Acridine structure correlated with mutagenic activity in Salmonella
    • Brown B., Firth W., Yielding L. Acridine structure correlated with mutagenic activity in Salmonella. Mutat. Res. 1980, 72:378-388.
    • (1980) Mutat. Res. , vol.72 , pp. 378-388
    • Brown, B.1    Firth, W.2    Yielding, L.3
  • 12
    • 0020620780 scopus 로고
    • Sensitivity of two Chinese hamster cell lines to SCE induction by a variety of chemical mutagens
    • Baker R., Mitchell G., Meher-Homji K., Podobna E. Sensitivity of two Chinese hamster cell lines to SCE induction by a variety of chemical mutagens. Mutat. Res. 1983, 118:103-116.
    • (1983) Mutat. Res. , vol.118 , pp. 103-116
    • Baker, R.1    Mitchell, G.2    Meher-Homji, K.3    Podobna, E.4
  • 13
    • 0022490195 scopus 로고
    • Chromosome aberrations induced by 9-aminoacridine derivatives
    • Michalska J. Chromosome aberrations induced by 9-aminoacridine derivatives. Mutat. Res. 1986, 170:119-123.
    • (1986) Mutat. Res. , vol.170 , pp. 119-123
    • Michalska, J.1
  • 14
    • 0018397173 scopus 로고
    • The induction of sister-chromatid exchanges by 9-aminoacridine derivatives. I. The relation between the yield of SCE induction and cell kinetics in cultured human lymphocytes
    • Giba Z., Limon J. The induction of sister-chromatid exchanges by 9-aminoacridine derivatives. I. The relation between the yield of SCE induction and cell kinetics in cultured human lymphocytes. Mutat. Res. 1979, 67:93-96.
    • (1979) Mutat. Res. , vol.67 , pp. 93-96
    • Giba, Z.1    Limon, J.2
  • 15
    • 0024470842 scopus 로고
    • Structure-activity relationships in the rat hepatocyte DNA-repair test for 300 chemicals
    • Williams G., Mori H., McQueen C.A. Structure-activity relationships in the rat hepatocyte DNA-repair test for 300 chemicals. Mutat. Res. 1989, 221:263-286.
    • (1989) Mutat. Res. , vol.221 , pp. 263-286
    • Williams, G.1    Mori, H.2    McQueen, C.A.3
  • 16
    • 0031973021 scopus 로고    scopus 로고
    • The ability of the comet assay to discriminate between genotoxins and cytotoxins
    • Henderson L., Wolfreys A., Fedyk J., Bourner C., Windebank S. The ability of the comet assay to discriminate between genotoxins and cytotoxins. Mutagenesis 1998, 13:89-94.
    • (1998) Mutagenesis , vol.13 , pp. 89-94
    • Henderson, L.1    Wolfreys, A.2    Fedyk, J.3    Bourner, C.4    Windebank, S.5
  • 17
    • 84937982703 scopus 로고    scopus 로고
    • monographs on evaluation of carcinogenic risks to humans:
    • alcohol consumption and ethyl carbamate
    • IARC monographs on evaluation of carcinogenic risks to humans: alcohol consumption and ethyl carbamate, 71 (2010).
    • (2010) , vol.71
  • 18
    • 0017391308 scopus 로고
    • Evaluation of the effect of ethanol on the frequency of micronuclei in the bone marrow of Swiss mice
    • Chaubey R.C., Kavi B.R., Chauhan P.S., Sundaram K. Evaluation of the effect of ethanol on the frequency of micronuclei in the bone marrow of Swiss mice. Mutat. Res. 1977, 43:441-444.
    • (1977) Mutat. Res. , vol.43 , pp. 441-444
    • Chaubey, R.C.1    Kavi, B.R.2    Chauhan, P.S.3    Sundaram, K.4
  • 19
    • 0027161092 scopus 로고
    • Coclastogenicity of ethanol with cigarette smoke in rat erythroblasts and anticlastogenicity in alveolar macrophages
    • Balansky R.M., Blagoeva P.M., Mircheva Z.I., de Flora S. Coclastogenicity of ethanol with cigarette smoke in rat erythroblasts and anticlastogenicity in alveolar macrophages. Cancer Lett. 1993, 72:183-189.
    • (1993) Cancer Lett. , vol.72 , pp. 183-189
    • Balansky, R.M.1    Blagoeva, P.M.2    Mircheva, Z.I.3    de Flora, S.4
  • 20
    • 84993822664 scopus 로고    scopus 로고
    • Toxicology and Carcinogenesis Studies of Urethane
    • Ethanol, and Urethane/ethanol, Technical Report 510, NIH Publication No. 04-4444
    • National Toxicology Program, Toxicology and Carcinogenesis Studies of Urethane, Ethanol, and Urethane/ethanol, Technical Report 510, NIH Publication No. 04-4444 (2004).
    • (2004)
  • 21
    • 0001406666 scopus 로고
    • Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals
    • McCann J., Choi E., Yamasaki E., Ames B.N. Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals. Proc. Natl. Acad. Sci. 1975, 72:5135-5139.
    • (1975) Proc. Natl. Acad. Sci. , vol.72 , pp. 5135-5139
    • McCann, J.1    Choi, E.2    Yamasaki, E.3    Ames, B.N.4
  • 23
    • 0018900387 scopus 로고
    • Point mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells. II. Test validation and interpretation
    • Amacher D.E., Paillet S.C., Turner G.N., Ray V.A., Salsburg D.S. Point mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells. II. Test validation and interpretation. Mutat. Res. 1980, 72:447-474.
    • (1980) Mutat. Res. , vol.72 , pp. 447-474
    • Amacher, D.E.1    Paillet, S.C.2    Turner, G.N.3    Ray, V.A.4    Salsburg, D.S.5
  • 24
    • 0021234444 scopus 로고
    • The in vitro micronucleus assay for detection of cytogenetic effects induced by mutagen-carcinogens: comparison with the in vitro sister-chromatid exchange assay
    • Lasne C., Gu Z.W., Venegas W., Chouroulinkov I. The in vitro micronucleus assay for detection of cytogenetic effects induced by mutagen-carcinogens: comparison with the in vitro sister-chromatid exchange assay. Mutat. Res. 1984, 130:273-282.
    • (1984) Mutat. Res. , vol.130 , pp. 273-282
    • Lasne, C.1    Gu, Z.W.2    Venegas, W.3    Chouroulinkov, I.4
  • 25
    • 0024582185 scopus 로고
    • Ethanol and acetaldehyde potentiate the clastogenicity of ultraviolet light methyl methanesulfonate, mitomycin C and bleomycin in Chinese hamster ovary cells
    • Lin Y.C., Ho I.C., Lee T.C. Ethanol and acetaldehyde potentiate the clastogenicity of ultraviolet light methyl methanesulfonate, mitomycin C and bleomycin in Chinese hamster ovary cells. Mutat. Res. 1989, 216:93-99.
    • (1989) Mutat. Res. , vol.216 , pp. 93-99
    • Lin, Y.C.1    Ho, I.C.2    Lee, T.C.3
  • 26
    • 79955449806 scopus 로고    scopus 로고
    • Chronic alcohol exposure induces genome damage measured using the cytokinesis-block micronucleus cytome assay and aneuploidy in human B lymphoblastoid cell lines
    • Benassi-Evans B., Fenech M. Chronic alcohol exposure induces genome damage measured using the cytokinesis-block micronucleus cytome assay and aneuploidy in human B lymphoblastoid cell lines. Mutagenesis 2011, 26:421-429.
    • (2011) Mutagenesis , vol.26 , pp. 421-429
    • Benassi-Evans, B.1    Fenech, M.2
  • 27
  • 28
    • 84937978932 scopus 로고
    • monographs on evaluation of carcinogenic risks to humans:
    • allyl compounds, aldehydes, epoxides and peroxides
    • IARC monographs on evaluation of carcinogenic risks to humans: allyl compounds, aldehydes, epoxides and peroxides, 36 (1985).
    • (1985) , vol.36


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.