Investigation of Lung Involvement in Connective Tissue Disorders

Respiration

Volumn 90, Issue 1, 2015, Pages 2-24

  Papiris, Spyros A ^a   Manali, Effrosyni D ^a   Kolilekas, Likurgos ^b   Kagouridis, Konstantinos ^a   Maniati, Maria ^a   Borie, Raphael ^d   Pradere, Pauline ^d   Crestani, Bruno ^d   Bouros, Demosthenes ^c  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^b SOTIRIA GENERAL HOSPITAL   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d INSERM   (France)

Author keywords

Ankylosing spondylitis; Apical fibrobullous disease; Bronchiolitis; Dermatomyositis polymyositis; Diffuse alveolar hemorrhage; Fibrotic nonspecific interstitial pneumonia; Infections; Mixed connective tissue disease; Pleuritis; Primary Sj gren's syndrome; Pulmonary arterial hypertension; Pulmonary embolism; Rheumatoid arthritis; Systemic lupus erythematosus; Systemic sclerosis; Usual interstitial pneumonia type pulmonary fibrosis

Indexed keywords

ANKYLOSING SPONDYLITIS; ASPIRATION PNEUMONIA; BRONCHIECTASIS; BRONCHIOLITIS; CONNECTIVE TISSUE DISEASE; DERMATOMYOSITIS; HUMAN; INTERSTITIAL LUNG DISEASE; INTERSTITIAL PNEUMONIA; LOEFFLER PNEUMONIA; LUNG CANCER; LUNG DISEASE; LUNG EMBOLISM; LUNG INFECTION; LUNG NODULE; LYMPHOPROLIFERATIVE DISEASE; MIXED CONNECTIVE TISSUE DISEASE; PLEURA EFFUSION; PLEURAL FIBROSIS; PNEUMOMEDIASTINUM; PNEUMOTHORAX; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RESPIRATORY TRACT DISEASE; REVIEW; RHEUMATOID ARTHRITIS; SCLERODERMA; SHRINKING LUNG SYNDROME; SJOEGREN SYNDROME; SLEEP DISORDERED BREATHING; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS; XEROSTOMIA; COMPLICATION; IMMUNOLOGY; LUNG DISEASES;

AUTOANTIBODY;

AUTOANTIBODIES; CONNECTIVE TISSUE DISEASES; HUMANS; LUNG DISEASES;

EID: 84937972444     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000435817     Document Type: Review

References (251)

1. Antin-Ozerkis D, Swigris J: Pulmonary complications of connective tissue disease. Semin Respir Crit Care Med 2014; 35: 157-158.
2. Assayag D, Ryerson CJ: Determining respiratory impairment in connective tissue diseaseassociated interstitial lung disease. Rheum Dis Clin North Am 2015; 41: 213-223.
3. Capobianco J, Grimberg A, Thompson BM, Antunes VB, Jasinowodolinski D, Meirelles GS: Thoracic manifestations of collagen vascular diseases. Radiographics 2012; 32: 33-50.
4. Jacob J, Nair A, Hansell DM: High-resolution computed tomography of the pulmonary manifestations of connective tissue diseases. Semin Respir Crit Care Med 2014; 35: 166-180.
5. Wells AU, Denton CP: Interstitial lung disease in connective tissue disease-mechanisms and management. Nat Rev Rheumatol 2014; 10: 728-739.
6. Higashiguchi M, Kijima T, Sumikawa H, Honda O, Minami T, Hirata H, Inoue K, Nagatomo I, Takeda Y, Kida H, Tomiyama N, Kumanogoh A: A retrospective study of prognostic factors in patients with interstitial pneumonia receiving long-term oxygen therapy. Lung 2014; 192: 729-737.
7. Nikpour M, Baron M: Mortality in systemic sclerosis: lessons learned from populationbased and observational cohort studies. Curr Opin Rheumatol 2014; 26: 131-137.
8. Horvath IF, Szanto A, Papp G, Zeher M: Clinical course, prognosis, and cause of death in primary Sjogren's syndrome. J Immunol Res 2014; 2014: 647507.
9. Humphreys JH, Warner A, Chipping J, Marshall T, Lunt M, Symmons DP, Verstappen SM: Mortality trends in patients with early rheumatoid arthritis over 20 years: results from the Norfolk Arthritis Register. Arthritis Care Res (Hoboken) 2014; 66: 1296-1301.
10. Lerang K, Gilboe IM, Steinar Thelle D, Gran JT: Mortality and years of potential life loss in systemic lupus erythematosus: A populationbased cohort study. Lupus 2014; 23: 1546-1552.
11. Santo AH, Souza JM, Pinheiro CE, Souza DC, Sato EI: Trends in dermatomyositis-and polymyositis-related mortality in the state of Sao Paulo, Brazil, 1985-2007: multiple causeof-death analysis. BMC Public Health 2010; 10: 597.
12. Bakland G, Gran JT, Nossent JC: Increased mortality in ankylosing spondylitis is related to disease activity. Ann Rheum Dis 2011; 70: 1921-1925.
13. Hajas A, Szodoray P, Nakken B, Gaal J, Zold E, Laczik R, Demeter N, Nagy G, Szekanecz Z, Zeher M, Szegedi G, Bodolay E: Clinical course, prognosis, and causes of death in mixed connective tissue disease. J Rheumatol 2013; 40: 1134-1142.
14. Agmon-Levin N, Damoiseaux J, Kallenberg C, Sack U, Witte T, Herold M, Bossuyt X, Musset L, Cervera R, Plaza-Lopez A, Dias C, Sousa MJ, Radice A, Eriksson C, Hultgren O, Viander M, Khamashta M, Regenass S, Andrade LE, Wiik A, Tincani A, Ronnelid J, Bloch DB, Fritzler MJ, Chan EK, Garcia-De La Torre I, Konstantinov KN, Lahita R, Wilson M, Vainio O, Fabien N, Sinico RA, Meroni P, Shoenfeld Y: International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies. Ann Rheum Dis 2014; 73: 17-23.
15. Mahler M, Meroni PL, Bossuyt X, Fritzler MJ: Current concepts and future directions for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies. J Immunol Res 2014; 2014: 315179.
16. Rehman HU: Antinuclear antibodies: when to test and how to interpret findings. J Fam Prac 2015; 64:E5-E8.
17. Wuyts WA, Cavazza A, Rossi G, Bonella F, Sverzellati N, Spagnolo P: Differential diagnosis of usual interstitial pneumonia: when is it truly idiopathic? Eur Respir Rev 2014; 23: 308-319.
18. Antoniou KM, Margaritopoulos G, Economidou F, Siafakas NM: Pivotal clinical dilemmas in collagen vascular diseases associated with interstitial lung involvement. Eur Respir J 2009; 33: 882-896.
19. Tzelepis GE, Toya SP, Moutsopoulos HM: Occult connective tissue diseases mimicking idiopathic interstitial pneumonias. Eur Respir J 2008; 31: 11-20.
20. Kim HC, Ji W, Kim MY, Colby TV, Jang SJ, Lee CK, Han SB, Kim DS: Interstitial pneumonia related to undifferentiated connective tissue disease: pathologic pattern and prognosis. Chest 2015; 147: 165-172.
21. Papiris SA, Kagouridis K, Bouros D: Serologic evaluation in idiopathic interstitial pneumonias. Curr Opin Pulm Med 2012; 18: 433-440.
22. Corte TJ, Copley SJ, Desai SR, Zappala CJ, Hansell DM, Nicholson AG, Colby TV, Renzoni E, Maher TM, Wells AU: Significance of connective tissue disease features in idiopathic interstitial pneumonia. Eur Respir J 2012; 39: 661-668.
23. Scott DL, Wolfe F, Huizinga TW: Rheumatoid arthritis. Lancet 2010; 376: 1094-1108.
24. Song YW, Kang EH: Autoantibodies in rheumatoid arthritis: rheumatoid factors and anticitrullinated protein antibodies. Q J Med 2010; 103: 139-146.
25. Lake F, Proudman S: Rheumatoid arthritis and lung disease: from mechanisms to a practical approach. Semin Respir Crit Care Med 2014; 35: 222-238.
26. Yunt ZX, Solomon JJ: Lung disease in rheumatoid arthritis. Rheum Dis Clin North Am 2015; 41: 225-236.
27. Brown KK: Rheumatoid lung disease. Proc Am Thorac Soc 2007; 4: 443-448.
28. Fischer A, Cosgrove GP: Interstitial lung abnormalities in rheumatoid arthritis are common and important. Chest 2014; 146: 8-10.
29. Vivero M, Padera RF: Histopathology of lung diseases in the connective tissue diseases. Rheum Dis Clin North Am 2015; 41: 197-211.
30. Kelly CA, Saravanan V, Nisar M, Arthanari S, Woodhead FA, Price-Forbes AN, Dawson J, Sathi N, Ahmad Y, Koduri G, Young A; British Rheumatoid Interstitial Lung (BRILL) Network: Rheumatoid arthritis-related interstitial lung disease: Associations, prognostic factors and physiological and radiological characteristics-a large multicentre UK study. Rheumatology (Oxford) 2014; 53: 1676-1682.
31. Solomon JJ, Ryu JH, Tazelaar HD, Myers JL, Tuder R, Cool CD, Curran-Everett D, Fischer A, Swigris JJ, Brown KK: Fibrosing interstitial pneumonia predicts survival in patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). Respir Med 2013; 107: 1247-1252.
32. Antoniou KM, Mamoulaki M, Malagari K, Kritikos HD, Bouros D, Siafakas NM, Boumpas DT: Infliximab therapy in pulmonary fibrosis associated with collagen vascular disease. Clin Exp Rheumatol 2007; 25: 23-28.
33. Assayag D, Elicker BM, Urbania TH, Colby TV, Kang BH, Ryu JH, King TE, Collard HR, Kim DS, Lee JS: Rheumatoid arthritis-associated interstitial lung disease: radiologic identification of usual interstitial pneumonia pattern. Radiology 2014; 270: 583-588.
34. Lee HK, Kim DS, Yoo B, Seo JB, Rho JY, Colby TV, Kitaichi M: Histopathologic pattern and clinical features of rheumatoid arthritisassociated interstitial lung disease. Chest 2005; 127: 2019-2027.
35. Smith M, Dalurzo M, Panse P, Parish J, Leslie K: Usual interstitial pneumonia-pattern fibrosis in surgical lung biopsies. Clinical, radiological and histopathological clues to aetiology. J Clin Pathol 2013; 66: 896-903.
36. Du Bois R, King TE Jr: Challenges in pulmonary fibrosis. 5. The NSIP/UIP debate. Thorax 2007; 62: 1008-1112.
37. Jani M, Hirani N, Matteson EL, Dixon WG: The safety of biologic therapies in RA-associated interstitial lung disease. Nat Rev Rheumatol 2014; 10: 284-294.
38. Vij R, Strek ME: Diagnosis and treatment of connective tissue disease-associated interstitial lung disease. Chest 2013; 143: 814-824.
39. De Lauretis A, Veeraraghavan S, Renzoni E: Review series: Aspects of interstitial lung disease: connective tissue disease-associated interstitial lung disease: how does it differ from IPF? How should the clinical approach differ? Chron Respir Dis 2011; 8: 53-82.
40. Henriet AC, Diot E, Marchand-Adam S, de Muret A, Favelle O, Crestani B, Diot P: Organising pneumonia can be the inaugural manifestation in connective tissue diseases, including Sjogren's syndrome. Eur Respir Rev 2010; 19: 161-163.
41. Papiris SA, Maniati MA, Kalousis JV, Constantopoulos SH: Chronic eosinophilic pneumonia in rheumatoid arthritis. Monaldi Arch Chest Dis 1995; 50: 360-362.
42. Tazelaar HD, Wright JL, Churg A: Desquamative interstitial pneumonia. Histopathology 2011; 58: 509-516.
43. Sigala I, Kalomenidis I, Malagari K, Rontogianni D, Kapotsis G, Vassilakopoulos T, Roussos C, Papiris SA: Dry cough and dyspnoea rapidly increasing to respiratory failure in a male smoker. Eur Respir J 2005; 25: 1122-1125.
44. Swartz MA, Vivino FB: Dramatic reversal of lymphocytic interstitial pneumonitis in Sjogren's syndrome with rituximab. J Clin Rheumatol 2011; 17: 454.
45. Cottin V, Nunes H, Mouthon L, Gamondes D, Lazor R, Hachulla E, Revel D, Valeyre D, Cordier JF; Groupe d'Etudes et de Recherche sur les Maladies 'Orphelines' Pulmonaires: Combined pulmonary fibrosis and emphysema syndrome in connective tissue disease. Arthritis Rheum 2011; 63: 295-304.
46. Balbir-Gurman A, Yigla M, Nahir AM, Braun-Moscovici Y: Rheumatoid pleural effusion. Semin Arthritis Rheum 2006; 35: 368-378.
47. Anevlavis S, Tzouvelekis A, Bouros D: Mechanisms of pleural involvement in orphan diseases. Respiration 2012; 83: 5-12
48. Bouros D, Pneumatikos I, Tzouvelekis A: Pleural involvement in systemic autoimmune disorders. Respiration 2008; 75: 361-371.
49. Avnon LS, Abu-Shakra M, Flusser D, Heimer D, Sion-Vardy N: Pleural effusion associated with rheumatoid arthritis: what cell predominance to anticipate? Rheumatol Int 2007; 27: 919-925.
50. Naylor B: The pathognomonic cytologic picture of rheumatoid pleuritis. The 1989 Maurice Goldblatt Cytology award lecture. Acta Cytol 1990; 34: 465-473.
51. Genzen JR, Motin A: Cholesterol crystals in pleural fluid. Am J Respir Crit Care Med 2012; 185: 586.
52. Ahmed R, Ahmed U, Syed I: Pneumothorax necessitans in a patient with trapped lung and rheumatoid arthritis. BMJ Case Rep 2013; 2013i:bcr2013009263.
53. Rueth N, Andrade R, Groth S, D'Cunha J, Maddaus M: Pleuropulmonary complications of rheumatoid arthritis: A thoracic surgeon's challenge. Ann Thorac Surg 2009; 88:e20-e21.
54. Kobayashi T, Satoh K, Ohkawa M, Satoh A: Multiple rheumatoid nodules with rapid thinwalled cavity formation producing pneumothorax. J Thorac Imag 2005; 20: 47-49.
55. Wilsher M, Voight L, Milne D, Teh M, Good N, Kolbe J, Williams M, Pui K, Merriman T, Sidhu K, Dalbeth N: Prevalence of airway and parenchymal abnormalities in newly diagnosed rheumatoid arthritis. Respir Med 2012; 106: 1441-1446.
56. Demoruelle MK, Weisman MH, Simonian PL, Lynch DA, Sachs PB, Pedraza IF, Harrington AR, Kolfenbach JR, Striebich CC, Pham QN, Strickland CD, Petersen BD, Parish MC, Derber LA, Norris JM, Holers VM, Deane KD: Brief report: Airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity? Arthritis Rheum 2012; 64: 1756-1761.
57. Geri G, Dadoun S, Bui T, Del Castillo Pinol N, Paternotte S, Dougados M, Gossec L: Risk of infections in bronchiectasis during diseasemodifying treatment and biologics for rheumatic diseases. BMC Infect Dis 2011; 11: 304.
58. Puechal X, Genin E, Bienvenu T, Le Jeunne C, Dusser DJ: Poor survival in rheumatoid arthritis associated with bronchiectasis: A family-based cohort study. PLoS One 2014; 9: e110066.
59. Devouassoux G, Cottin V, Liote H, Marchand E, Frachon I, Schuller A, Bejui-Thivolet F, Cordier JF; Groupe d'Etudes et de Recherche sur les Maladies 'Orphelines' Pulmonaires: Characterisation of severe obliterative bronchiolitis in rheumatoid arthritis. Eur Respir J 2009; 33: 1053-1061.
60. Hamdan AL, Sarieddine D: Laryngeal manifestations of rheumatoid arthritis. Autoimmune Dis 2013; 2013: 103081.
61. Peters JE, Burke CJ, Morris VH: Three cases of rheumatoid arthritis with laryngeal stridor. Clin Rheumatol 2011; 30: 723-727.
62. Beumer HM, van Belle CJ: Pulmonary nodules in rheumatoid arthritis. Respiration 1972; 29: 556-564.
63. Gomez Herrero H, Arraiza Sarasa M, Rubio Marco I, Garcia de Eulate Martin-Moro I: Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases. Rheumatol Clin 2012; 8: 212-215.
64. Highton J, Hessian PA, Stamp L: The rheumatoid nodule: peripheral or central to rheumatoid arthritis? Rheumatology (Oxford) 2007; 46: 1385-1387.
65. Saraya T, Tanaka R, Fujiwara M, Koji H, Oda M, Ogawa Y, Nagatomo T, Watanabe M, Yokoyama T, Ishii H, Takei H, Goya T, Takizawa H, Goto H: Fluorodeoxyglucose (FDG) uptake in pulmonary rheumatoid nodules diagnosed by video-assisted thoracic surgery lung biopsy: Two case reports and a review of the literature. Mod Rheumatol 2013; 23: 393-396.
66. Schreiber J, Koschel D, Kekow J, Waldburg N, Goette A, Merget R: Rheumatoid pneumoconiosis (Caplan's syndrome). Eur J Intern Med 2010; 21: 168-172.
67. Shariff N, Kumar A, Narang R, Malhotra A, Mukhopadhyaya S, Sharma SK: A study of pulmonary arterial hypertension in patients with rheumatoid arthritis. Int J Cardiol 2007; 115: 75-76.
68. Chung WS, Peng CL, Lin CL, Chang YJ, Chen YF, Chiang JY, Sung FC, Kao CH: Rheumatoid arthritis increases the risk of deep vein thrombosis and pulmonary thromboembolism: A nationwide cohort study. Ann Rheum Dis 2014; 73: 1774-1780.
69. Sadeghi S, Granton JT, Akhavan P, Pasarikovski CR, Roos AM, Thenganatt J, Moric J, Johnson SR: Survival in rheumatoid arthritis-associated pulmonary arterial hypertension compared with idiopathic pulmonary arterial hypertension. Respirology 2015; 20: 481-487.
70. Bely M, Apathy A: Amyloid A deposition in rheumatoid arthritis: A retrospective clinicopathologic study of 161 autopsy patients. Amyloid 2012; 19: 212-213.
71. Schwarz MI, Zamora MR, Hodges TN, Chan ED, Bowler RP, Tuder RM: Isolated pulmonary capillaritis and diffuse alveolar hemorrhage in rheumatoid arthritis and mixed connective tissue disease. Chest 1998; 113: 1609-1615.
72. Tsokos GC: Systemic lupus erythematosus. N Engl J Med 2011; 365: 2110-2121.
73. Compagno M, Rekvig OP, Bengtsson AA, Sturfelt G, Heegaard NH, Jonsen A, Jacobsen RS, Eilertsen GO, Fenton CG, Truedsson L, Nossent JC, Jacobsen S: Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study. Lupus Sci Med 2014; 1:e000007.
74. Rekvig OP, Van der Vlag J: The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved. Semin Immunopathol 2014; 36: 301-311.
75. Mittoo S, Fell CD: Pulmonary manifestations of systemic lupus erythematosus. Semin Respir Crit Care Med 2014; 35: 249-254.
76. Allen D, Fischer A, Bshouty Z, Robinson DB, Peschken CA, Hitchon C, El-Gabalawy H, Meyers M, Mittoo S: Evaluating systemic lupus erythematosus patients for lung involvement. Lupus 2012; 21: 1316-1325.
77. Lisnevskaia L, Murphy G, Isenberg D: Systemic lupus erythematosus. Lancet 2014; 384: 1878-1888.
78. Weng CT, Chung TJ, Liu MF, Weng MY, Lee CH, Chen JY, Wu AB, Lin BW, Luo CY, Hsu SC, Lee BF, Tsai HM, Chao SC, Wang JY, Chen TY, Chen CW, Chang HY, Wang CR: A retrospective study of pulmonary infarction in patients with systemic lupus erythematosus from southern Taiwan. Lupus 2011; 20: 876-885.
79. Kim JS, Lee KS, Koh EM, Kim SY, Chung MP, Han J: Thoracic involvement of systemic lupus erythematosus: clinical, pathologic, and radiologic findings. J Comput Assist Tomogr 2000; 24: 9-18.
80. Zandman-Goddard G, Shoenfeld Y: SLE and infections. Clin Rev Allergy Immunol 2003; 25: 29-40.
81. Cuchacovich R, Gedalia A: Pathophysiology and clinical spectrum of infections in systemic lupus erythematosus. Rheum Dis Clin North Am 2009; 35: 75-93.
82. Feldman CH, Hiraki LT, Winkelmayer WC, Marty FM, Franklin JM, Kim SC, Costenbader KH: Serious infections among adult Medicaid beneficiaries with systemic lupus erythematosus and lupus nephritis. Arthritis Rheumatol 2015; 67: 1577-1585.
83. Tektonidou MG, Wang Z, Dasgupta A, Ward MM: Burden of serious infections in adults with systemic lupus erythematosus. A national population-based study, 1996-2011. Arthritis Care Res (Hoboken) 2015, Epub ahead of print.
84. Danza A, Ruiz-Irastorza G: Infection risk in systemic lupus erythematosus patients: susceptibility factors and preventive strategies. Lupus 2013; 22: 1286-1294.
85. Hellmann DB, Petri M, Whiting-O'Keefe Q: Fatal infections in systemic lupus erythematosus: The role of opportunistic organisms. Medicine (Baltimore) 1987; 66: 341-348.
86. Palavutitotai N, Buppajarntham T, Katchamart W: Etiologies and outcomes of pleural effusions in patients with systemic lupus erythematosus. J Clin Rheumatol 2014; 20: 418-421.
87. Torre O, Harari S: Pleural and pulmonary involvement in systemic lupus erythematosus. Presse Med 2011; 40:e19-e29.
88. Wang DY: Diagnosis and management of lupus pleuritis. Curr Opin Pulm Med 2002; 8: 312-316.
89. Bouros D, Panagou P, Papandreou L, Kottakis I, Tegos C: Massive bilateral pleural effusion as the only first presentation of systemic lupus erythematosus. Respiration 1992; 59: 173-175.
90. Man BL, Mok CC: Serositis related to systemic lupus erythematosus: prevalence and outcome. Lupus 2005; 14: 822-826.
91. Sarzi-Puttini P, Atzeni F, Capsoni F, Lubrano E, Doria A: Drug-induced lupus erythematosus. Autoimmunity 2005; 38: 507-518.
92. Bazzan M, Vaccarino A, Marletto F: Systemic lupus erythematosus and thrombosis. Thromb J 2015; 13: 16.
93. Sallai KK, Nagy E, Bodo I, Mohl A, Gergely P: Thrombosis risk in systemic lupus erythematosus: The role of thrombophilic risk factors. Scand J Rheumatol 2007; 36: 198-205.
94. Ruiz-Irastorza G, Crowther M, Branch W, Khamashta MA: Antiphospholipid syndrome. Lancet 2010; 376: 1498-1509.
95. Schreiber BE, Connolly MJ, Coghlan JG: Pulmonary hypertension in systemic lupus erythematosus. Best Pract Res Clin Rheumatol 2013; 27: 425-434.
96. Wiedermann FJ, Lederer W, Sepp N, Schobersberger W: ARDS in catastrophic antiphospholipid syndrome. Lupus 2001; 10: 382-383.
97. Cervera R, Serrano R, Pons-Estel GJ, Ceberio-Hualde L, Shoenfeld Y, de Ramon E, Buonaiuto V, Jacobsen S, Zeher MM, Tarr T, Tincani A, Taglietti M, Theodossiades G, Nomikou E, Galeazzi M, Bellisai F, Meroni PL, Derksen RH, de Groot PG, Baleva M, Mosca M, Bombardieri S, Houssiau F, Gris JC, Quere I, Hachulla E, Vasconcelos C, Fernandez-Nebro A, Haro M, Amoura Z, et al: Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: A multicentre prospective study of 1,000 patients. Ann Rheum Dis 2015; 74: 1011-1018.
98. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, de Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006; 4: 295-306.
99. Keeling D, Mackie I, Moore GW, Greer IA, Greaves M; British Committee for Standards in Haematology: Guidelines on the investigation and management of antiphospholipid syndrome. Br J Haematol 2012; 157: 47-58.
100. Zoller B, Li X, Sundquist J, Sundquist K: Risk of pulmonary embolism in patients with autoimmune disorders: A nationwide followup study from Sweden. Lancet 2012; 379: 244-249.
101. Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galie N, Gibbs JS, Huisman MV, Humbert M, Kucher N, Lang I, Lankeit M, Lekakis J, Maack C, Mayer E, Meneveau N, Perrier A, Pruszczyk P, Rasmussen LH, Schindler TH, Svitil P, Vonk Noordegraaf A, Zamorano JL, Zompatori M; Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC): 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J 2014; 35: 3033-3069.
102. Lang IM, Pesavento R, Bonderman D, Yuan JX: Risk factors and basic mechanisms of chronic thromboembolic pulmonary hypertension: A current understanding. Eur Respir J 2013; 41: 462-468.
103. Kim NH, Delcroix M, Jenkins DP, Channick R, Dartevelle P, Jansa P, Lang I, Madani MM, Ogino H, Pengo V, Mayer E: Chronic thromboembolic pulmonary hypertension. J Am Coll Cardiol 2013; 62:D92-D99.
104. Galie N, Corris PA, Frost A, Girgis RE, Granton J, Jing ZC, Klepetko W, McGoon MD, McLaughlin VV, Preston IR, Rubin LJ, Sandoval J, Seeger W, Keogh A: Updated treatment algorithm of pulmonary arterial hypertension. J Am Coll Cardiol 2013; 62:D60-D72.
105. Cervera R, Rodriguez-Pinto I, Espinosa G; Task Force on Catastrophic Antiphospholipid Syndrome: Catastrophic antiphospholipid syndrome: Task force report summary. Lupus 2014; 23: 1283-1285.
106. Zamora MR, Warner ML, Tuder R, Schwarz MI: Diffuse alveolar hemorrhage and systemic lupus erythematosus. Clinical presentation, histology, survival, and outcome. Medicine (Baltimore) 1997; 76: 192-202.
107. Kwok SK, Moon SJ, Ju JH, Park KS, Kim WU, Cho CS, Kim HY, Park SH: Diffuse alveolar hemorrhage in systemic lupus erythematosus: risk factors and clinical outcome: results from affiliated hospitals of Catholic University of Korea. Lupus 2011; 20: 102-107.
108. Gutsche M, Rosen GD, Swigris JJ: Connective tissue disease-associated interstitial lung disease: A review. Curr Respir Care Rep 2012; 1: 224-232.
109. Reynolds JA, Toescu V, Yee CS, Prabu A, Situnayake D, Gordon C: Effects of rituximab on resistant SLE disease including lung involvement. Lupus 2009; 18: 67-73.
110. Papiris SA, Kagouridis K, Papadaki G, Kolilekas L, Manali ED: Treating CTDs related fibrotic ILDs by the immunosuppressants: 'facts and faults'. Lung 2014; 192: 221-223.
111. Warrington KJ, Moder KG, Brutinel WM: The shrinking lungs syndrome in systemic lupus erythematosus. Mayo Clin Proc 2000; 75: 467-472.
112. Carmier D, Diot E, Diot P: Shrinking lung syndrome: recognition, pathophysiology and therapeutic strategy. Expert Rev Respir Med 2011; 5: 33-39.
113. Penacoba Toribio P, Corica Albani ME, Mayos Perez M, Rodriguez de la Serna A: Rituximab in the treatment of shrinking lung syndrome in systemic lupus erythematosus. Rheumatol Clin 2014; 10: 325-327.
114. Esmaeilbeigi F, Juvet S, Hwang D, Mittoo S: Desquamative interstitial pneumonitis and systemic lupus erythematosus. Can Respir J 2012; 19: 50-52.
115. Martens J, Demedts M, Vanmeenen MT, Dequeker J: Respiratory muscle dysfunction in systemic lupus erythematosus. Chest 1983; 84: 170-175.
116. Myers JL, Katzenstein AA: Microangiitis in lupus induced pulmonary hemorrhage. Am J Clin Pathol 1986; 85: 552-556.
117. Andonopoulos AP: Adult respiratory distress syndrome: An unrecognized premortem event in systemic lupus erythematosus. Br J Rheumatol 1991; 30: 346-348.
118. Simonson JS, Schiller NB, Petri M, Hellmann DB: Pulmonary hypertension in systemic lupus erythematosus. J Rheumatol 1989; 16: 918-925.
119. Abramson SB, Dobro J, Eberle MA, Benton M, Reibman J, Epstein H, Rapoport DM, Belmont HM, Goldring RM: Acute reversible hypoxemia in systemic lupus erythematosus. Ann Intern Med 1991; 114: 941-947.
120. Teitel AD, MacKenzie CR, Stern R, Paget SA: Laryngeal involvement in systemic lupus erythematosus. Semin Arthritis Rheum 1992; 22: 203-214.
121. Langford CA, Van Waes C: Upper airway obstruction in the rheumatic diseases. Rheum Dis Clin North Am 1997; 23: 345-363.
122. Keane MP, Lynch JP 3rd: Pleuropulmonary manifestations of systemic lupus erythematosus. Thorax 2000; 55: 159-166.
123. Lateef O, Shakoor N, Balk RA: Methotrexate pulmonary toxicity. Expert Opin Drug Saf 2005; 4: 723-730.
124. Tansey D, Wells AU, Colby TV, Nikolakoupolou A, du Bois RM, Hansell DM, Nicholson AG: Variations in histological patterns of interstitial pneumonia between connective tissue disorders and their relationship to prognosis. Histopathology 2004; 44: 585-596.
125. Gammon RB, Bridges TA, al-Nezir H, Alexander CB, Kennedy JI Jr: Bronchiolitis obliterans organizing pneumonia associated with systemic lupus erythematosus. Chest 1992; 102: 1171-1174.
126. Takada H, Saito Y, Nomura A, Ohga S, Kuwano K, Nakashima N, Aishima S, Tsuru N, Hara T: Bronchiolitis obliterans organizing pneumonia as an initial manifestation in systemic lupus erythematosus. Pediatr Pulmonol 2005; 40: 257-260.
127. Smith GA, Ward PH, Berci G: Laryngeal lupus erythematosus. J Laryngol Otol 1978; 92: 67-73.
128. Hariri LP, Unizony S, Stone J, Mino-Kenudson M, Sharma A, Matsubara O, Mark EJ: Acute fibrinous and organizing pneumonia in systemic lupus erythematosus: A case report and review of the literature. Pathol Int 2010; 60: 755-759.
129. Sharma S, Smith R, Al-Hameed F: Fibrothorax and severe lung restriction secondary to lupus pleuritis and its successful treatment by pleurectomy. Can Respir J 2002; 9: 335-337.
130. Shim SS, Chun EM, Sung SH: Unusual diffuse pulmonary amyloidosis in systemic lupus erythematosus: computed tomography findings. Clin Imaging 2011; 35: 156-159.
131. Cloutier BT, Clarke AE, Ramsey-Goldman R, Gordon C, Hansen JE, Bernatsky S: Systemic lupus erythematosus and malignancies: A review article. Rheum Dis Clin North Am 2014; 40: 497-506.
132. Gabrielli A, Avvedimento EV, Krieg T: Scleroderma. N Engl J Med 2009; 360: 1989-2003.
133. Van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, Muller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, et al: 2013 classification criteria for systemic sclerosis: An American College of Rheumatology/ European League against Rheumatism collaborative initiative. Arthritis Rheum 2013; 65: 2737-2747.
134. Hachulla E, Launay D: Diagnosis and classification of systemic sclerosis. Clin Rev Allergy Immunol 2011; 40: 78-83.
135. Chaisson NF, Hassoun PM: Systemic sclerosis-associated pulmonary arterial hypertension. Chest 2013; 144: 1346-1356.
136. Tyndall A, Fistarol S: The differential diagnosis of systemic sclerosis. Curr Opin Rheumatol 2013; 25: 692-699.
137. Schoenfeld SR, Castelino FV: Interstitial lung disease in scleroderma. Rheum Dis Clin North Am 2015; 41: 237-248.
138. Wells AU: Interstitial lung disease in systemic sclerosis. Presse Med 2014; 43:e329-e343.
139. Colaci M, Sebastiani M, Manfredi A, Giuggioli D, Cassone G, Manzini CU, Ghizzoni C, Cerri S, Ferri C: Lung involvement in systemic sclerosis: role of high resolution computed tomography and its relationship with other pulmonary and clinico-serological features. J Biol Regul Homeost Agents 2014; 28: 481-488.
140. Frauenfelder T, Winklehner A, Nguyen TD, Dobrota R, Baumueller S, Maurer B, Distler O: Screening for interstitial lung disease in systemic sclerosis: performance of high-resolution CT with limited number of slices: A prospective study. Ann Rheum Dis 2014; 73: 2069-2073.
141. Wells AU, Margaritopoulos GA, Antoniou KM, Denton C: Interstitial lung disease in systemic sclerosis. Semin Respir Crit Care Med 2014; 35: 213-221.
142. Bouros D, Wells AU, Nicholson AG, Colby TV, Polychronopoulos V, Pantelidis P, Haslam PL, Vassilakis DA, Black CM, du Bois RM: Histopathologic subsets of fibrosing alveolitis in patients with systemic sclerosis and their relationship to outcome. Am J Respir Crit Care Med 2002; 165: 1581-1586.
143. Bussone G, Mouthon L: Interstitial lung disease in systemic sclerosis. Autoimmun Rev 2011; 10: 248-255.
144. Ahmed SS, Johnson SR, Meaney C, Chau C, Marras TK: Lung function and survival in systemic sclerosis interstitial lung disease. J Rheumatol 2014; 41: 2326-2328.
145. Nihtyanova SI, Schreiber BE, Ong VH, Rosenberg D, Moinzadeh P, Coghlan JG, Wells AU, Denton CP: Prediction of pulmonary complications and long-term survival in systemic sclerosis. Arthritis Rheumatol 2014; 66: 1625-1635.
146. Battaglia S, Bellia M, Serafino-Agrusa L, Giardina A, Messina M, Cannizzaro F, Midiri M, Triolo G, Scichilone N: Physical capacity in performing daily activities is reduced in scleroderma patients with early lung involvement. Clin Respir J 2015, Epub ahead of print.
147. Someya F, Mugii N, Hasegawa M, Yahata T, Nakagawa T: Predictors of exercise-induced oxygen desaturation in systemic sclerosis patients with interstitial lung disease. Respir Care 2014; 59: 75-80.
148. Solomon JJ, Olson AL, Fischer A, Bull T, Brown KK, Raghu G: Scleroderma lung disease. Eur Respir Rev 2013; 22: 6-19.
149. Diab S, Dostrovsky N, Hudson M, Tatibouet S, Fritzler MJ, Baron M, Khalidi N; Canadian Scleroderma Research Group: Systemic sclerosis sine scleroderma: A multicenter study of 1,417 subjects. J Rheumatol 2014; 41: 2179-2185.
150. Lo Monaco A, Govoni M, Trotta F: Digital clubbing or digital 'pseudoclubbing' in systemic sclerosis. J Clin Rheumatol 2006; 12: 97.
151. Nihtyanova SI, Ong VH, Denton CP: Current management strategies for systemic sclerosis. Clin Exp Rheumatol 2014; 32: 156-164.
152. Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, Gomez Sanchez MA, Krishna Kumar R, Landzberg M, Machado RF, Olschewski H, Robbins IM, Souza R: Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2013; 62:D34-D41.
153. Chung L, Farber HW, Benza R, Miller DP, Parsons L, Hassoun PM, McGoon M, Nicolls MR, Zamanian RT: Unique predictors of mortality in patients with pulmonary arterial hypertension associated with systemic sclerosis in the REVEAL registry. Chest 2014; 146: 1494-1504.
154. Ghosh SK, Corkill MM, Hart HH, Ng KP: Screening for pulmonary arterial hypertension in patients with scleroderma-a New Zealand perspective. NZ Med J 2014; 127: 30-38.
155. Schwaiger JP, Khanna D, Gerry Coghlan J: Screening patients with scleroderma for pulmonary arterial hypertension and implications for other at-risk populations. Eur Respir Rev 2013; 22: 515-525.
156. Steen V, Medsger TA Jr: Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement. Arthritis Rheum 2003; 48: 516-522.
157. Kherbeck N, Tamby MC, Bussone G, Dib H, Perros F, Humbert M, Mouthon L: The role of inflammation and autoimmunity in the pathophysiology of pulmonary arterial hypertension. Clin Rev Allergy Immunol 2013; 44: 31-38.
158. Prabu A, Gordon C: Pulmonary arterial hypertension in SLE: what do we know? Lupus 2013; 22: 1274-1285.
159. Highland KB: Recent advances in scleroderma-associated pulmonary hypertension. Curr Opin Rheumatol 2014; 26: 637-645.
160. Gashouta MA, Humbert M, Hassoun PM: Update in systemic sclerosis-associated pulmonary arterial hypertension. Presse Med 2014; 43:e293-e304.
161. Coghlan JG, Schreiber B: An update on the evaluation and management of pulmonary hypertension in scleroderma. Curr Rheumatol Rep 2012; 14: 1-10.
162. Launay D, Savale L, Berezne A, Le Pavec J, Hachulla E, Mouthon L, Sitbon O, Lambert B, Gaudric M, Jais X, Stephan F, Hatron PY, Lamblin N, Vignaux O, Cottin V, Farge D, Wallaert B, Guillevin L, Simonneau G, Mercier O, Fadel E, Dartevelle P, Humbert M, Mussot S; Working Group on Heart/Lung Transplantation in Systemic Sclerosis of the French Network on Pulmonary Hypertension: Lung and heart-lung transplantation for systemic sclerosis patients. A monocentric experience of 13 patients, review of the literature and position paper of a multidisciplinary Working Group. Presse Med 2014; 43:e345-e363.
163. Roumm AD, Medsger TA Jr: Cancer and systemic sclerosis. Arthritis Rheum 1985; 28: 1336-1340.
164. Rosenthal AK, McLaughlin JK, Gridley G, Nyren O: Incidence of cancer among patients with systemic sclerosis. Cancer 1995; 76: 910-914.
165. Hill CL, Nguyen AM, Roder D, Roberts-Thomson P: Risk of cancer in patients with scleroderma: A population based cohort study. Ann Rheum Dis 2003; 62: 728-731.
166. Hant FN, Herpel LB, Silver RM: Pulmonary manifestations of scleroderma and mixed connective tissue disease. Clin Chest Med 2010; 31: 433-449.
167. Highland KB, Garin MC, Brown KK: The spectrum of scleroderma lung disease. Semin Respir Crit Care Med 2007; 28: 418-429.
168. Adzi TN, Pesut DP, Nagorni-Obradovi LM, Stojsi JM, Vasiljevi MD, Bouros D: Clinical features of lung cancer in patients with connective tissue diseases: A 10-year hospital based study. Respir Med 2008; 102: 620-624.
169. Yang Y, Fujita J, Tokuda M, Bandoh S, Ishida T: Lung cancer associated with several connective tissue diseases: with a review of literature. Rheumatol Int 2001; 21: 106-111.
170. Kang KY, Yim HW, Kim IJ, Yoon JU, Ju JH, Kim HY, Park SH: Incidence of cancer among patients with systemic sclerosis in Korea: results from a single centre. Scand J Rheumatol 2009; 38: 299-303.
171. Peters-Golden M, Wise RA, Hochberg M, Stevens MB, Wigley FM: Incidence of lung cancer in systemic sclerosis. J Rheumatol 1985; 12: 1136-1139.
172. Bonifazi M, Tramacere I, Pomponio G, Gabrielli B, Avvedimento EV, La Vecchia C, Negri E, Gabrielli A: Systemic sclerosis (scleroderma) and cancer risk: systematic review and meta-analysis of observational studies. Rheumatology (Oxford) 2013; 52: 143-154.
173. Daniels CE, Jett JR: Does interstitial lung disease predispose to lung cancer? Curr Opin Pulm Med 2005; 11: 431-437.
174. Ma Y, Seneviratne CK, Koss M: Idiopathic pulmonary fibrosis and malignancy. Curr Opin Pulm Med 2001; 7: 278-282.
175. Hazleman B: Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens. Am J Med 1985; 78: 39-43.
176. Archontogeorgis K, Steiropoulos P, Tzouvelekis A, Nena E, Bouros D: Lung cancer and interstitial lung diseases: A systematic review. Pulm Med 2012; 2012: 315918.
177. Dalakas MC: Inflammatory muscle diseases. N Engl J Med 2015; 372: 1734-1747.
178. Fathi M, Vikgren J, Boijsen M, Tylen U, Jorfeldt L, Tornling G, Lundberg IE: Interstitial lung disease in polymyositis and dermatomyositis: longitudinal evaluation by pulmonary function and radiology. Arthritis Rheum 2008; 59: 677-685.
179. Marie I, Hatron PY, Dominique S, Cherin P, Mouthon L, Menard JF: Short-term and long-term outcomes of interstitial lung disease in polymyositis and dermatomyositis: A series of 107 patients. Arthritis Rheum 2011; 63: 3439-3447.
180. Kalluri M, Oddis CV: Pulmonary manifestations of the idiopathic inflammatory myopathies. Clin Chest Med 2010; 31: 501-512.
181. Cha SI, Fessler MB, Cool CD, Schwarz MI, Brown KK: Lymphoid interstitial pneumonia: clinical features, associations and prognosis. Eur Respir J 2006; 28: 364-369.
182. Beasley MB, Franks TJ, Galvin JR, Gochuico B, Travis WD: Acute fibrinous and organizing pneumonia: A histological pattern of lung injury and possible variant of diffuse alveolar damage. Arch Pathol Lab Med 2002; 126: 1064-1070.
183. Schwarz MI, Sutarik JM, Nick JA, Leff JA, Emlen JW, Tuder RM: Pulmonary capillaritis and diffuse alveolar hemorrhage. A primary manifestation of polymyositis. Am J Respir Crit Care Med 1995; 151: 2037-2040.
184. Iijima Y, Furusawa H, Tateishi T, Tsuchiya K, Fujie T, Tamaoka M, Sakashita H, Miyazaki Y, Sumi Y, Hosono Y, Nakashima R, Mimori T, Inase N: Amyopathic dermatomyositis complicated with eosinophilic pneumonia. Intern Med 2014; 53: 1539-1544.
185. Tang R, Millett CR, Green JJ: Amyopathic dermatomyositis complicated by pneumomediastinum. J Clin Aesthet Dermatol 2013; 6: 40-43.
186. Hamaguchi Y, Fujimoto M, Matsushita T, Kaji K, Komura K, Hasegawa M, Kodera M, Muroi E, Fujikawa K, Seishima M, Yamada H, Yamada R, Sato S, Takehara K, Kuwana M: Common and distinct clinical features in adult patients with anti-aminoacyltRNA synthetase antibodies: heterogeneity within the syndrome. PLoS One 2013; 8:e60442.
187. Fischer A, Swigris JJ, du Bois RM, Lynch DA, Downey GP, Cosgrove GP, Frankel SK, Fernandez-Perez ER, Gillis JZ, Brown KK: Antisynthetase syndrome in ANA and anti-Jo-1 negative patients presenting with idiopathic interstitial pneumonia. Respir Med 2009; 103: 1719-1724.
188. Hozumi H, Enomoto N, Kono M, Fujisawa T, Inui N, Nakamura Y, Sumikawa H, Johkoh T, Nakashima R, Imura Y, Mimori T, Suda T: Prognostic significance of antiaminoacyl-tRNA synthetase antibodies in polymyositis/dermatomyositis-associated interstitial lung disease: A retrospective case control study. PLoS One 2015; 10:e0120313.
189. Marie I, Josse S, Decaux O, Diot E, Landron C, Roblot P, Jouneau S, Hatron PY, Hachulla E, Vittecoq O, Menard JF, Jouen F, Dominique S: Clinical manifestations and outcome of anti-PL7 positive patients with antisynthetase syndrome. Eur J Intern Med 2013; 24: 474-479.
190. Vancsa A, Csipo I, Nemeth J, Devenyi K, Gergely L, Danko K: Characteristics of interstitial lung disease in SS-A positive/Jo-1 positive inflammatory myopathy patients. Rheumatol Int 2009; 29: 989-994.
191. Suda T, Fujisawa T, Enomoto N, Nakamura Y, Inui N, Naito T, Hashimoto D, Sato J, Toyoshima M, Hashizume H, Chida K: Interstitial lung diseases associated with amyopathic dermatomyositis. Eur Respir J 2006; 28: 1005-1012.
192. Ye S, Chen XX, Lu XY, Wu MF, Deng Y, Huang WQ, Guo Q, Yang CD, Gu YY, Bao CD, Chen SL: Adult clinically amyopathic dermatomyositis with rapid progressive interstitial lung disease: A retrospective cohort study. Clin Rheumatol 2007; 26: 1647-1654.
193. Zou J, Guo Q, Chi J, Wu H, Bao C: HRCT score and serum ferritin level are factors associated to the 1-year mortality of acute interstitial lung disease in clinically amyopathic dermatomyositis patients. Clin Rheumatol 2015; 34: 707-714.
194. Labrador-Horrillo M, Martinez MA, Selva-O'Callaghan A, Trallero-Araguas E, Balada E, Vilardell-Tarres M, Juarez C: Anti-MDA5 antibodies in a large Mediterranean population of adults with dermatomyositis. J Immunol Res 2014; 2014: 290797.
195. Gono T, Kaneko H, Kawaguchi Y, Hanaoka M, Kataoka S, Kuwana M, Takagi K, Ichida H, Katsumata Y, Ota Y, Kawasumi H, Yamanaka H: Cytokine profiles in polymyositis and dermatomyositis complicated by rapidly progressive or chronic interstitial lung disease. Rheumatology (Oxford) 2014; 53: 2196-2203.
196. Kawasumi H, Gono T, Kawaguchi Y, Kaneko H, Katsumata Y, Hanaoka M, Kataoka S, Yamanaka H: IL-6, IL-8, and IL-10 are associated with hyperferritinemia in rapidly progressive interstitial lung disease with polymyositis/ dermatomyositis. Biomed Res Int 2014; 2014: 815245.
197. Fujisawa T, Hozumi H, Kono M, Enomoto N, Hashimoto D, Nakamura Y, Inui N, Yokomura K, Koshimizu N, Toyoshima M, Shirai T, Yasuda K, Hayakawa H, Suda T: Prognostic factors for myositis-associated interstitial lung disease. PLoS One 2014; 9:e98824.
198. Moutsopoulos HM, Chused TM, Mann DL, Klippel JH, Fauci AS, Frank MM, Lawley TJ, Hamburger MI: Sjogren's syndrome (Sicca syndrome): current issues. Ann Intern Med 1980; 92: 212-226.
199. Moutsopoulos HM: Sjogren's syndrome: Autoimmune epithelitis. Clin Immunol Immunopathol 1994; 72: 162-165.
200. Mitsias DI, Kapsogeorgou ED, Moutsopoulos HM: The role of epithelial cells in the initiation and perpetuation of autoimmune lesions: lessons from Sjogren's syndrome (autoimmune epithelitis). Lupus 2006; 15: 255-261.
201. Triantafyllopoulou A, Tapinos N, Moutsopoulos HM: Evidence of coxsackie virus infection in primary Sjogren's syndrome. Arthritis Rheum 2004; 50: 2897-2902.
202. Bunim JJ, Talal N: The association of malignant lymphoma with Sjogren's syndrome. Trans Assoc Am Physicians 1963; 76: 45.
203. Kassan SS, Thomas TL, Moutsopoulos HM, Hoover R, Kimberly RP, Budman DR, Costa J, Decker JL, Chused TM: Increased risk of lymphoma in sicca syndrome. Ann Intern Med 1978; 89: 888-892.
204. Papiris SA, Kalomenidis I, Malagari K, Kapotsis GE, Harhalakis N, Manali ED, Rontogianni D, Roussos C, Moutsopoulos HM: Extranodal marginal zone B-cell lymphoma of the lung in Sjogren's syndrome patients: reappraisal of clinical, radiological, and pathology findings. Respir Med 2007; 101: 84-92.
205. Sjogren H: On knowledge of kerataconjunctivitis sicca. Keratitis filiformis due to lacrimal gland hypofunction. Acta Ophthalmol 1933;suppl 2: 1-151.
206. Papiris SA, Moutsopoulos HM: Sjogren's syndrome and the lung; in Wells AU, Denton CP (eds): Handbook of Systemic Autoimmune Diseases. Amsterdam, Elsevier, 2004, vol 2, pp 161-180.
207. Papiris SA, Kassan S, Moutsopoulos HM: The lung in Sjogren's syndrome. Semin Respir Crit Care Med 1999; 20: 179-184.
208. Papiris SA, Tsonis I, Moutsopoulos HM: Pulmonary complications in Sjogren's syndrome. Semin Respir Crit Care Med 2007; 28: 459-472.
209. Constantopoulos SH, Papadimitriou CS, Moutsopoulos HM: Respiratory manifestations in primary Sjogren's syndrome: A clinical, functional and histologic study. Chest 1985; 88: 226-229.
210. Papathanasiou MP, Constantopoulos SH, Tsampoulas C: Reappraisal of respiratory abnormalities in primary and secondary Sjogren's syndrome. A controlled study. Chest 1986; 90: 370-374.
211. Papiris SA, Saetta M, Turato G, La Corte R, Trevisani L, Mapp CE, Maestrelli P, Fabbri L, Potena A: CD4 positive T-lymphocytes infiltrate the bronchial mucosa in patients with Sjogren's syndrome. Am J Respir Crit Care Med 1997; 156: 637-641.
212. Newball HH, Brahim SA: Chronic obstructive airway disease in patients with Sjogren's syndrome. Am Rev Respir Dis 1977; 115: 295.
213. Papiris SA, Maniati MA, Constantopoulos SH, Roussos Ch, Moutsopoulos HM, Skopouli FN: Lung involvement in primary Sjogren's syndrome is mainly related to the small airway disease. Ann Rheum Dis 1999; 58: 61-64.
214. Parambil JG, Myers JL, Lindell RM, Matteson EL, Ryu JH: Interstitial lung disease in primary Sjogren's syndrome. Chest 2006; 130: 1489-1495.
215. Ito I, Nagai S, Kitaichi M, Nicholson AG, Johkoh T, Noma S, Kim DS, Handa T, Izumi T, Mishima M: Pulmonary manifestations of primary Sjogren's syndrome: A clinical, radiologic and pathologic study. Am J Respir Crit Care Med 2005; 171: 632-638.
216. Adzi TN, Stojsi JM, Radosavljevi-Asi GD, Bouros D: Multinodular pulmonary amyloidosis in primary Sjogren's syndrome. Eur J Intern Med 2008; 19:e97-e98.
217. Tani C, Carli L, Vagnani S, Talarico R, Baldini C, Mosca M, Bombardieri S: The diagnosis and classification of mixed connective tissue disease. J Autoimmun 2014; 48-49: 46-49.
218. Mira-Avendano IC, Abril A: Pulmonary manifestations of Sjogren's syndrome, systemic lupus erythematosus and mixed connective tissue disease. Rheum Dis Clin North Am 2015; 41: 263-277.
219. Hant FN, Herpel LB, Silver RM: Pulmonary manifestations of scleroderma and connective tissue disease. Clin Chest Med 2010; 31: 433-449.
220. McBrien C, Penketh A, Johnson H, Nicholson AG, Wells A: Recurrent pneumothoraces in a 17-year-old man with mixed connective tissue disease. Thorax 2014; 69: 685-686.
221. Yang MC, Blutreich A, Das K: Nodular pulmonary amyloidosis with an unusual protein composition diagnosed by fine-needle aspiration biopsy: A case report. Diagn Cytopathol 2009; 37: 286-289.
222. Martens J, Demedts M: Diaphragm dysfunction in mixed connective tissue disease. A case report. Scand J Rheumatol 1982; 11: 165-167.
223. Gunnarsson R, Aalokken TM, Molberg O, Lund MB, Mynarek GK, Lexberg AS, Time K, Dhainaut AS, Bertelsen LT, Palm O, Irgens K, Becker-Merok A, Nordeide JL, Johnsen V, Pedersen S, Proven A, Garabet LS, Gran JT: Prevalence and severity of interstitial lung disease in mixed connective tissue disease: A nationwide, cross-sectional study. Ann Rheum Dis 2012; 71: 1966-1972.
224. Ortega-Hernandez OD, Shoenfeld Y: Mixed connective tissue disease: An overview of clinical manifestations, diagnosis and treatment. Best Pract Res Clin Rheumatol 2012; 26: 61-72.
225. Kawano-Dourado L, Baldi BG, Kay FU, Dias OM, Gripp TE, Gomes PS, Fuller R, Caleiro MT, Kairalla RA, Carvalho CR: Pulmonary involvement in long-term mixed connective tissue disease: functional trends and image findings after 10 years. Clin Exp Rheumatol 2015; 33: 234-240.
226. Braun J, Sieper J: Ankylosing spondylitis. Lancet 2007; 369: 1379-1390.
227. Douganos M, Baeten D: Spondyloarthritis. Lancet 2011; 377: 2127-2137.
228. Durnham CL, Kautz FG: Spondyloarthritis ankylopoietica. A review and report of twenty cases. Am J Med Sci 1941; 201: 232-250.
229. Hamilton KA: Pulmonary disease manifestations of ankylosing spondylarthritis. Ann Intern Med 1949; 31: 216-227.
230. Daikh DI, Chen PP: Advances in managing ankylosing spondylitis. F1000Prime Rep 2014; 6: 78.
231. Kanathur N, Lee-Chiong T: Pulmonary manifestations of ankylosing spondylitis. Clin Chest Med 2010; 31: 547-554.
232. Romagnoli I, Gigliotti F, Galarducci A, Lanini B, Bianchi R, Cammelli D, Scano G: Chest wall kinematics and respiratory muscle action in ankylosing spondylitis patients. Eur Respir J 2004; 24: 453-460.
233. Rumancik WM, Firooznia H, Davis MS, Leitman BS, Golimbu C, Rafii M, McCauley DI: Fibrobullous disease of the upper lobes: An extraskeletal manifestation of ankylosing spondylitis. J Comput Tomogr 1984; 8: 225-229.
234. Blavia R, Toda MR, Vidal F, Benet A, Razquin S, Richart C: Pulmonary diffuse amyloidosis and ankylosing spondylitis. Chest 1992; 102: 1608-1610.
235. Rosenow E, Strimlan CV, Muhm JR, Ferguson RH: Pleuropulmonary manifestations of ankylosing spondylitis. Mayo Clin Proc 1977; 52: 641-649.
236. Libby DM, Schley WS, Smith JP: Cricoarytenoid arthritis in ankylosing spondylitis. A cause of acute respiratory failure and cor pulmonale. Chest 1981; 80: 641-643.
237. Repo UK, Kentala E, Koistinen J, Lehtipuu AL, Miettinen A, Pyrhonen S, Tiilikainen A, Vuornos T: Pulmonary apical fibrocystic disease. Eur J Respir Dis 1981; 62: 46-55.
238. Ferdoutis M, Bouros D, Meletis G, Patsourakis G, Siafakas NM: Diffuse interstitial lung disease as an early manifestation of ankylosing spondylitis. Respiration 1995; 62: 286-289.
239. Lee CC, Lee SH, Chang IJ, Lu TC, Yuan A, Chang TA, Tsai KC, Chen WJ: Spontaneous pneumothorax associated with ankylosing spondylitis. Rheumatology 2005; 44: 1538-1541.
240. Erb N, Karokis D, Delamere JP, Cushley MJ, Kitas GD: Obstructive sleep apnea as a cause of fatigue in ankylosing spondylitis. Ann Rheum Dis 2003; 62: 183-184.
241. Solak O, Fidan F, Dundar U, Turel A, Aycicek A, Kavuncu V, Unlu M: The prevalence of obstructive sleep apnea syndrome in ankylosing spondylitis patients. Rheumatology 2009; 48: 433-435.
242. Rhagae PK, Tarrasa BC: Bronchocentric granulomatosis and ankylosing spondylitis. Thorax 1984; 39: 317-318.
243. Turner JF, Ensnarer RJ: Bronchiolitis obliterans and organizing pneumonia associated with ankylosing spondylitis. Arthritis Rheum 1994; 37: 1557-1559.
244. Richly DJ, Dipper JT: Infections associated with tumor necrosis factor antagonists. Pharmacotherapy 2005; 25: 1181-1192.
245. Scobie BA: Disturbed oesophageal manometric responses in patients with ankylosing spondylitis and pulmonary aspergilloma. Australas Ann Med 1970; 19: 131-134.
246. Berdal G, Halvorsen S, van der Heijde D, Mowe M, Dagfinrud H: Restrictive pulmonary function is more prevalent in patients with ankylosing spondylitis than in matched population controls and is associated with impaired spinal mobility: A comparative study. Arthritis Res Ther 2012; 14:R19.
247. Fournie B, Boutes A, Dromer C, Sixou L, Le Guennec P, Granel J, Railhac JJ: Prospective study of anterior chest wall involvement in ankylosing spondylitis and psoriatic arthritis. Rev Rhum Engl Ed 1997; 64: 22-25.
248. Brambila-Tapia AJ, Rocha-Munoz AD, Gonzalez-Lopez L, Vazquez-Del-Mercado M, Salazar-Paramo M, Davalos-Rodriguez IP, De la Cerda-Trujillo L, Diaz-Toscano ML, Hernandez-Cuervo P, Diaz-Rizo V, Sanchez-Mosco D, Vazquez-Jimenez JC, Cardona-Munoz EG, Gamez-Nava JI: Pulmonary function in ankylosing spondylitis: Association with clinical variables. Rheumatol Int 2013; 33: 2351-2358.
249. Fortoul TI, Cano-Valle F, Oliva E, Barrios R: Follicular bronchiolitis in association with connective tissue diseases. Lung 1985; 163: 305-314.
250. Ho HH, Lin MC, Yu KH, Wang CM, Wu YJ, Chen JY: Pulmonary tuberculosis and disease-related pulmonary apical fibrosis in ankylosing spondylitis. J Rheumatol 2009; 36: 355-360.
251. Momeni M, Taylor N, Tehrani M: Cardiopulmonary Manifestations of Ankylosing Spondylitis. Int J Rheumatol 2011; 2011: 728471.