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Volumn 32, Issue SUPPL.81, 2014, Pages

Current management strategies for systemic sclerosis

Author keywords

Systemic sclerosis; Treatment

Indexed keywords

HUMANS; IMMUNOSUPPRESSIVE AGENTS; SCLERODERMA, SYSTEMIC; STEROIDS;

EID: 84898799747     PISSN: 0392856X     EISSN: 1593098X     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (35)

References (114)
  • 1
    • 84859844674 scopus 로고    scopus 로고
    • Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise with the ACR/EULAR working committee for classification criteria in systemic sclerosis
    • FRANSEN J, JOHNSON SR, Van Den HOOGEN F et al.: Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise with the ACR/EULAR working committee for classification criteria in systemic sclerosis. Arthritis Care Res 2012; 64: 351-7.
    • (2012) Arthritis Care Res , vol.64 , pp. 351-357
    • Fransen, J.1    Johnson, S.R.2    Van Den Hoogen, F.3
  • 2
    • 84859815866 scopus 로고    scopus 로고
    • Validation of potential classification criteria for systemic sclerosis
    • JOHNSON SR, FRANSEN J, KHANNA D et al.: Validation of potential classification criteria for systemic sclerosis. Arthritis Care Res 2012; 64: 358-67.
    • (2012) Arthritis Care Res , vol.64 , pp. 358-367
    • Johnson, S.R.1    Fransen, J.2    Khanna, D.3
  • 3
    • 84886777196 scopus 로고    scopus 로고
    • 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative
    • Van den HOOGEN F, KHANNA D, FRANSEN J et al.:2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum 2013; 65: 2737-47.
    • (2013) Arthritis Rheum , vol.65 , pp. 2737-2747
    • Van den Hoogen, F.1    Khanna, D.2    Fransen, J.3
  • 4
    • 0023006120 scopus 로고
    • Different antibody patterns and different prognoses in patients with scleroderma with various extent of skin sclerosis
    • GIORDANO M, VALENTINI G, MIGLIARESI S, PICILLO U, VATTI M: Different antibody patterns and different prognoses in patients with scleroderma with various extent of skin sclerosis. J Rheumatol 1986; 13: 911-6.
    • (1986) J Rheumatol , vol.13 , pp. 911-916
    • Giordano, M.1    Valentini, G.2    Migliaresi, S.3    Picillo, U.4    Vatti, M.5
  • 5
    • 4444321458 scopus 로고    scopus 로고
    • A working classification of scleroderma spectrum disorders: A proposal and the results of testing on a sample of patients
    • MARICQ HR, VALTER I: A working classification of scleroderma spectrum disorders: A proposal and the results of testing on a sample of patients. Clin Exp Rheumatol 2004; 22: S5-13.
    • (2004) Clin Exp Rheumatol , vol.22
    • Maricq, H.R.1    Valter, I.2
  • 6
    • 0023854176 scopus 로고
    • Scleroderma (systemic sclerosis): classification, subsets and pathogenesis
    • LeROY EC, BLACK C, FLEISCHMAJER R et al.: Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988; 15: 202-5.
    • (1988) J Rheumatol , vol.15 , pp. 202-205
    • LeRoy, E.C.1    Black, C.2    Fleischmajer, R.3
  • 7
    • 0033758222 scopus 로고    scopus 로고
    • Skin thickness score as a predictor and correlate of outcome in systemic sclerosis high-dose versus low-dose penicillamine trial
    • CLEMENTS PJ, HURWITZ EL, WONG WKEE et al.: Skin thickness score as a predictor and correlate of outcome in systemic sclerosis high-dose versus low-dose penicillamine trial. 2000; 43: 2445-54.
    • (2000) , vol.43 , pp. 2445-2454
    • Clements, P.J.1    Hurwitz, E.L.2    Wong, W.K.E.E.3
  • 8
    • 0035678255 scopus 로고    scopus 로고
    • Improvement in skin thickening in systemic sclerosis associated with improved survival
    • STEEN VD, MEDSGER TA: Improvement in skin thickening in systemic sclerosis associated with improved survival. Arthritis Rheum 2001; 44: 2828-35.
    • (2001) Arthritis Rheum , vol.44 , pp. 2828-2835
    • Steen, V.D.1    Medsger, T.A.2
  • 9
    • 34547485497 scopus 로고    scopus 로고
    • Relationship between change in skin score and disease outcome in diffuse cutaneous systemic sclerosis: application of a latent linear trajectory model
    • SHAND L, LUNT M, NIHTYANOVA S et al.: Relationship between change in skin score and disease outcome in diffuse cutaneous systemic sclerosis: application of a latent linear trajectory model. Arthritis Rheum 2007; 56: 2422-31.
    • (2007) Arthritis Rheum , vol.56 , pp. 2422-2431
    • Shand, L.1    Lunt, M.2    Nihtyanova, S.3
  • 10
    • 84899917327 scopus 로고    scopus 로고
    • The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis
    • [Epub ahead of print]
    • COTTRELL TR, WISE RA, WIGLEY FM, BOIN F: The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis. Ann Rheum Dis 2013. [Epub ahead of print]
    • (2013) Ann Rheum Dis
    • Cottrell, T.R.1    Wise, R.A.2    Wigley, F.M.3    Boin, F.4
  • 11
    • 57349145191 scopus 로고    scopus 로고
    • Skin sclerosis is only of limited value to identify SSc patients with severe manifestations - an analysis of a distinct patient subgroup of the German Systemic Sclerosis Network (DNSS) Register
    • HANITSCH LG, BURMESTER G, WITT C et al.: Skin sclerosis is only of limited value to identify SSc patients with severe manifestations - an analysis of a distinct patient subgroup of the German Systemic Sclerosis Network (DNSS) Register 2009; 70-3.
    • (2009) , pp. 70-73
    • Hanitsch, L.G.1    Burmester, G.2    Witt, C.3
  • 12
    • 34547743765 scopus 로고    scopus 로고
    • Clinical subsets, skin thickness progression rate, and serum antibody levels in systemic sclerosis patients with anti-topoisomerase I antibody
    • PERERA A, FERTIG N, LUCAS M et al.: Clinical subsets, skin thickness progression rate, and serum antibody levels in systemic sclerosis patients with anti-topoisomerase I antibody. Arthritis Rheum 2007; 56: 2740-6.
    • (2007) Arthritis Rheum , vol.56 , pp. 2740-2746
    • Perera, A.1    Fertig, N.2    Lucas, M.3
  • 13
    • 0037653223 scopus 로고    scopus 로고
    • Correlation of serum anti-DNA topoisomerase I antibody levels with disease severity and activity in systemic sclerosis
    • HU PQ, FERTIG N, MEDSGER TA, WRIGHT TM: Correlation of serum anti-DNA topoisomerase I antibody levels with disease severity and activity in systemic sclerosis. Arthritis Rheum 2003; 48: 1363-73.
    • (2003) Arthritis Rheum , vol.48 , pp. 1363-1373
    • Hu, P.Q.1    Fertig, N.2    Medsger, T.A.3    Wright, T.M.4
  • 14
    • 0034083130 scopus 로고    scopus 로고
    • Longitudinal analysis of autoantibody response to topoisomerase I in systemic sclerosis
    • KUWANA M, KABURAKI J, MIMORI T, KAWAKAMI Y, TOJO T: Longitudinal analysis of autoantibody response to topoisomerase I in systemic sclerosis. Arthritis Rheum 2000; 43: 1074-84.
    • (2000) Arthritis Rheum , vol.43 , pp. 1074-1084
    • Kuwana, M.1    Kaburaki, J.2    Mimori, T.3    Kawakami, Y.4    Tojo, T.5
  • 15
    • 70350787026 scopus 로고    scopus 로고
    • A longitudinal study of anti-RNA polymerase III antibody levels in systemic sclerosis
    • (Oxford)
    • NIHTYANOVA SI, PARKER JC, BLACK CM, BUNN CC, DENTON CP: A longitudinal study of anti-RNA polymerase III antibody levels in systemic sclerosis. Rheumatology (Oxford) 2009; 48: 1218-21.
    • (2009) Rheumatology , vol.48 , pp. 1218-1221
    • Nihtyanova, S.I.1    Parker, J.C.2    Black, C.M.3    Bunn, C.C.4    Denton, C.P.5
  • 16
    • 0345700825 scopus 로고    scopus 로고
    • The association of antinuclear antibodies with organ involvement and survival in systemic sclerosis
    • HESSELSTRAND R: The association of antinuclear antibodies with organ involvement and survival in systemic sclerosis. Rheumatology 2003; 42: 534-40.
    • (2003) Rheumatology , vol.42 , pp. 534-540
    • Hesselstrand, R.1
  • 17
    • 34248379222 scopus 로고    scopus 로고
    • Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database
    • WALKER U, TYNDALL A, CZIRJÁK L et al.: Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database. Ann Rheum Dis 2007; 66: 754-63.
    • (2007) Ann Rheum Dis , vol.66 , pp. 754-763
    • Walker, U.1    Tyndall, A.2    Czirják, L.3
  • 18
    • 0027979362 scopus 로고
    • Clinical and prognostic associations based on serum antinuclear antibodies in Japanese patients with systemic sclerosis
    • KUWANA M, KABURAKI J, OKANO Y, TOJO T, HOMMA M: Clinical and prognostic associations based on serum antinuclear antibodies in Japanese patients with systemic sclerosis. Arthritis Rheum 1994; 37: 75-83.
    • (1994) Arthritis Rheum , vol.37 , pp. 75-83
    • Kuwana, M.1    Kaburaki, J.2    Okano, Y.3    Tojo, T.4    Homma, M.5
  • 19
    • 0345700825 scopus 로고    scopus 로고
    • The association of antinuclear antibodies with organ involvement and survival in systemic sclerosis
    • (Oxford)
    • HESSELSTRAND R, SCHEJA A, SHEN GQ, WIIK A, AKESSON A: The association of antinuclear antibodies with organ involvement and survival in systemic sclerosis. Rheumatology (Oxford) 2003; 42: 534-40.
    • (2003) Rheumatology , vol.42 , pp. 534-540
    • Hesselstrand, R.1    Scheja, A.2    Shen, G.Q.3    Wiik, A.4    Akesson, A.5
  • 20
    • 39049137455 scopus 로고    scopus 로고
    • The clinical relevance of serum antinuclear antibodies in Japanese patients with systemic sclerosis
    • HAMAGUCHI Y, HASEGAWA M, FUJIMOTO M et al.: The clinical relevance of serum antinuclear antibodies in Japanese patients with systemic sclerosis. Br J Dermatol 2008; 158: 487-95.
    • (2008) Br J Dermatol , vol.158 , pp. 487-495
    • Hamaguchi, Y.1    Hasegawa, M.2    Fujimoto, M.3
  • 21
    • 34547822481 scopus 로고    scopus 로고
    • Scleroderma renal crisis: patient characteristics and long-term outcomes
    • PENN H, HOWIE AJ, KINGDON EJ et al.: Scleroderma renal crisis: patient characteristics and long-term outcomes. QJM 2007; 100: 485-94.
    • (2007) QJM , vol.100 , pp. 485-494
    • Penn, H.1    Howie, A.J.2    Kingdon, E.J.3
  • 22
    • 0031856993 scopus 로고    scopus 로고
    • Anti-RNA polymerases and other autoantibody specificities in systemic sclerosis
    • BUNN CC, DENTON CP, SHI-WEN X, KNIGHT C, BLACK CM: Anti-RNA polymerases and other autoantibody specificities in systemic sclerosis. Br J Rheumatol 1998; 37: 15-20.
    • (1998) Br J Rheumatol , vol.37 , pp. 15-20
    • Bunn, C.C.1    Denton, C.P.2    Shi-Wen, X.3    Knight, C.4    Black, C.M.5
  • 24
    • 0032189278 scopus 로고    scopus 로고
    • Analysis of autoantibodies against RNA polymerases using immunoaffinity-purifed RNA polymerase I, II, and III antigen in an enzyme-linked immunosorbent assay
    • CHANG M, WANG RJ, YANGCO DT, SHARP GC, KOMATIREDDY GR, HOFFMAN RW: Analysis of autoantibodies against RNA polymerases using immunoaffinity-purifed RNA polymerase I, II, and III antigen in an enzyme-linked immunosorbent assay. Clin Immunol Immunopathol 1998; 89: 71-8.
    • (1998) Clin Immunol Immunopathol , vol.89 , pp. 71-78
    • Chang, M.1    Wang, R.J.2    Yangco, D.T.3    Sharp, G.C.4    Komatireddy, G.R.5    Hoffman, R.W.6
  • 25
    • 23644457672 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent assay for detection of anti-RNA polymerase III antibody: analytical accuracy and clinical associations in systemic sclerosis
    • KUWANA M, OKANO Y, PANDEY JP, SILVER RM, FERTIG N, MEDSGER TA: Enzyme-linked immunosorbent assay for detection of anti-RNA polymerase III antibody: analytical accuracy and clinical associations in systemic sclerosis. Arthritis Rheum 2005; 52: 2425-32.
    • (2005) Arthritis Rheum , vol.52 , pp. 2425-2432
    • Kuwana, M.1    Okano, Y.2    Pandey, J.P.3    Silver, R.M.4    Fertig, N.5    Medsger, T.A.6
  • 26
    • 0034782193 scopus 로고    scopus 로고
    • Anti-fibrillarin antibodies in systemic sclerosis
    • (Oxford)
    • TORMEY VJ, BUNN CC, DENTON CP, BLACK CM: Anti-fibrillarin antibodies in systemic sclerosis. Rheumatology (Oxford) 2001; 40: 1157-62.
    • (2001) Rheumatology , vol.40 , pp. 1157-1162
    • Tormey, V.J.1    Bunn, C.C.2    Denton, C.P.3    Black, C.M.4
  • 28
    • 67650504632 scopus 로고    scopus 로고
    • Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis
    • FERTIG N, DOMSIC RT, RODRIGUEZ-REYNA T et al.: Anti-U11/U12 RNP antibodies in systemic sclerosis: a new serologic marker associated with pulmonary fibrosis. Arthritis Rheum 2009; 61: 958-65.
    • (2009) Arthritis Rheum , vol.61 , pp. 958-965
    • Fertig, N.1    Domsic, R.T.2    Rodriguez-Reyna, T.3
  • 29
    • 0037231639 scopus 로고    scopus 로고
    • A comparison between anti-Th/To- and anticentromere antibody-positive systemic sclerosis patients with limited cutaneous involvement
    • MITRI GM, LUCAS M, FERTIG N, STEEN VD, MEDSGER TA: A comparison between anti-Th/To- and anticentromere antibody-positive systemic sclerosis patients with limited cutaneous involvement. Arthritis Rheum 2003; 48: 203-9.
    • (2003) Arthritis Rheum , vol.48 , pp. 203-209
    • Mitri, G.M.1    Lucas, M.2    Fertig, N.3    Steen, V.D.4    Medsger, T.A.5
  • 30
    • 84881138875 scopus 로고    scopus 로고
    • Targeted therapies for systemic sclerosis
    • DENTON CP, ONG VH: Targeted therapies for systemic sclerosis. Nat Rev Rheumatol 2013: 9: 451-64.
    • Nat Rev Rheumatol , vol.2013 , Issue.9 , pp. 451-464
    • Denton, C.P.1    Ong, V.H.2
  • 31
    • 33745227399 scopus 로고    scopus 로고
    • Cyclophosphamide versus placebo in scleroderma lung disease
    • TASHKIN DP, ELASHOFF R, CLEMENTS PJ et al.: Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med 2006; 354: 2655-66.
    • (2006) N Engl J Med , vol.354 , pp. 2655-2666
    • Tashkin, D.P.1    Elashoff, R.2    Clements, P.J.3
  • 32
    • 33845643063 scopus 로고    scopus 로고
    • A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma
    • HOYLES RK, ELLIS RW, WELLSBURY J et al.: A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma. Arthritis Rheum 2006; 54: 3962-70.
    • (2006) Arthritis Rheum , vol.54 , pp. 3962-3970
    • Hoyles, R.K.1    Ellis, R.W.2    Wellsbury, J.3
  • 33
    • 0035144259 scopus 로고    scopus 로고
    • Pilot study of anti-thymocyte globulin plus mycophenolate mofetil in recent-onset diffuse scleroderma
    • (Oxford)
    • STRATTON RJ, WILSON H, BLACK CM: Pilot study of anti-thymocyte globulin plus mycophenolate mofetil in recent-onset diffuse scleroderma. Rheumatology (Oxford) 2001; 40: 84-8.
    • (2001) Rheumatology , vol.40 , pp. 84-88
    • Stratton, R.J.1    Wilson, H.2    Black, C.M.3
  • 34
    • 33847394965 scopus 로고    scopus 로고
    • Mycophenolate mofetil in diffuse cutaneous systemic sclerosis--a retrospective analysis
    • (Oxford)
    • NIHTYANOVA SI, BROUGH GM, BLACK CM, DENTON CP: Mycophenolate mofetil in diffuse cutaneous systemic sclerosis--a retrospective analysis. Rheumatology (Oxford) 2007; 46: 442-5.
    • (2007) Rheumatology , vol.46 , pp. 442-445
    • Nihtyanova, S.I.1    Brough, G.M.2    Black, C.M.3    Denton, C.P.4
  • 35
    • 84861821762 scopus 로고    scopus 로고
    • A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset
    • MENDOZA FA, NAGLE SJ, LEE JB, JIMENEZ SA: A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset. J Rheumatol 2012; 39: 1241-7.
    • (2012) J Rheumatol , vol.39 , pp. 1241-1247
    • Mendoza, F.A.1    Nagle, S.J.2    Lee, J.B.3    Jimenez, S.A.4
  • 36
    • 75649109604 scopus 로고    scopus 로고
    • A prospective open-label study of mycophenolate mofetil for the treatment of diffuse systemic sclerosis
    • (Oxford)
    • DERK CT, GRACE E, SHENIN M, NAIK M, SCHULZ S, XIONG W: A prospective open-label study of mycophenolate mofetil for the treatment of diffuse systemic sclerosis. Rheumatology (Oxford) 2009; 48: 1595-9.
    • (2009) Rheumatology , vol.48 , pp. 1595-1599
    • Derk, C.T.1    Grace, E.2    Shenin, M.3    Naik, M.4    Schulz, S.5    Xiong, W.6
  • 37
    • 0034970031 scopus 로고    scopus 로고
    • A randomized, controlled trial of methotrexate versus placebo in early diffuse scleroderma
    • POPE JE, BELLAMY N, SEIBOLD JR et al.: A randomized, controlled trial of methotrexate versus placebo in early diffuse scleroderma. Arthritis Rheum 2001; 44: 1351-8.
    • (2001) Arthritis Rheum , vol.44 , pp. 1351-1358
    • Pope, J.E.1    Bellamy, N.2    Seibold, J.R.3
  • 38
    • 0029867337 scopus 로고    scopus 로고
    • Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial
    • Van den HOOGEN FH, BOERBOOMS AM, SWAAK AJ, RASKER JJ, van LIER HJ, van de PUTTE LB: Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial. Br J Rheumatol 1996; 35: 364-72.
    • (1996) Br J Rheumatol , vol.35 , pp. 364-372
    • Van den Hoogen, F.H.1    Boerbooms, A.M.2    Swaak, A.J.3    Rasker, J.J.4    van Lier, H.J.5    van de Putte, L.B.6
  • 39
    • 80051468836 scopus 로고    scopus 로고
    • Auto-logous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial
    • BURT RK, SHAH SJ, DILL K et al.: Auto-logous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial. Lancet 2011; 378: 498-506.
    • (2011) Lancet , vol.378 , pp. 498-506
    • Burt, R.K.1    Shah, S.J.2    Dill, K.3
  • 40
    • 84898830398 scopus 로고    scopus 로고
    • High dose immunoablation and autologous hematopoietic stem cell transplantation versus monthly intravenous pulse therapy cyclophosphamide in severe systemic sclerosis
    • Van LAAR JM, FARGE D, SONT JK et al.: High dose immunoablation and autologous hematopoietic stem cell transplantation versus monthly intravenous pulse therapy cyclophosphamide in severe systemic sclerosis. 2012: 64: 4167-74.
    • , vol.2012 , Issue.64 , pp. 4167-4174
    • Van Laar, J.M.1    Farge, D.2    Sont, J.K.3
  • 41
    • 84873741331 scopus 로고    scopus 로고
    • Therapeutic inhibition of tyrosine kinases in systemic sclerosis: a review of published experience on the first 108 patients treated with imatinib
    • BOURNIA V-K, EVANGELOU K, SFIKAKIS PP: Therapeutic inhibition of tyrosine kinases in systemic sclerosis: a review of published experience on the first 108 patients treated with imatinib. Semin Arthritis Rheum 2013; 42: 377-90.
    • (2013) Semin Arthritis Rheum , vol.42 , pp. 377-390
    • Bournia, V.-K.1    Evangelou, K.2    Sfikakis, P.P.3
  • 42
    • 79955860261 scopus 로고    scopus 로고
    • Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial
    • SPIERA RF, GORDON JK, MERSTEN JN et al.: Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial. Ann Rheum Dis 2011; 70: 1003-9.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1003-1009
    • Spiera, R.F.1    Gordon, J.K.2    Mersten, J.N.3
  • 43
    • 84859248430 scopus 로고    scopus 로고
    • A multi-center, open-label, proof of concept study of imatinib mesylate demonstrates no benefit for the treatment of fibrosis in patients with early, diffuse systemic sclerosis
    • DISTLER O, DISTLER J, VARGA J et al.: A multi-center, open-label, proof of concept study of imatinib mesylate demonstrates no benefit for the treatment of fibrosis in patients with early, diffuse systemic sclerosis. Arthritis Rheum 2010; 62: S233.
    • (2010) Arthritis Rheum , vol.62
    • Distler, O.1    Distler, J.2    Varga, J.3
  • 44
    • 80155204477 scopus 로고    scopus 로고
    • A one-year, phase I/IIa, open-label pilot trial of imatinib mesylate in the treatment of systemic sclerosis-associated active interstitial lung disease
    • KHANNA D, SAGGAR R, MAYES MD et al.: A one-year, phase I/IIa, open-label pilot trial of imatinib mesylate in the treatment of systemic sclerosis-associated active interstitial lung disease. Arthritis Rheum 2011; 63: 3540-6.
    • (2011) Arthritis Rheum , vol.63 , pp. 3540-3546
    • Khanna, D.1    Saggar, R.2    Mayes, M.D.3
  • 45
    • 84868214290 scopus 로고    scopus 로고
    • Imatinib mesylate in scleroderma-associated diffuse skin fibrosis: a phase II multicentre randomized double-blinded controlled trial
    • PREY S, EZZEDINE K, DOUSSAU A et al.: Imatinib mesylate in scleroderma-associated diffuse skin fibrosis: a phase II multicentre randomized double-blinded controlled trial. Br J Dermatol 2012; 167: 1138-44.
    • (2012) Br J Dermatol , vol.167 , pp. 1138-1144
    • Prey, S.1    Ezzedine, K.2    Doussau, A.3
  • 46
    • 80155206225 scopus 로고    scopus 로고
    • Imatinib in active diffuse cutaneous systemic sclerosis: Results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center
    • POPE J, McBAIN D, PETRLICH L et al.: Imatinib in active diffuse cutaneous systemic sclerosis: Results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center. Arthritis Rheum 2011; 63: 3547-51.
    • (2011) Arthritis Rheum , vol.63 , pp. 3547-3551
    • Pope, J.1    Mcbain, D.2    Petrlich, L.3
  • 47
    • 77950443096 scopus 로고    scopus 로고
    • Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study
    • (Oxford)
    • DAOUSSIS D, LIOSSIS S-NC, TSAMANDAS AC et al.: Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study. Rheumatology (Oxford) 2010; 49: 271-80.
    • (2010) Rheumatology , vol.49 , pp. 271-280
    • Daoussis, D.1    Liossis, S.-N.C.2    Tsamandas, A.C.3
  • 48
    • 84867383069 scopus 로고    scopus 로고
    • Effect of long-term treatment with rituximab on pulmonary function and skin fibrosis in patients with diffuse systemic sclerosis
    • DAOUSSIS D, LIOSSIS S-NC, TSAMANDAS AC et al.: Effect of long-term treatment with rituximab on pulmonary function and skin fibrosis in patients with diffuse systemic sclerosis. Clin Exp Rheumatol 2012; 30: S17-22.
    • (2012) Clin Exp Rheumatol , vol.30
    • Daoussis, D.1    Liossis, S.-N.C.2    Tsamandas, A.C.3
  • 49
    • 73449095775 scopus 로고    scopus 로고
    • Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study
    • SMITH V, Van PRAET JT, VANDOOREN B et al.: Rituximab in diffuse cutaneous systemic sclerosis: an open-label clinical and histopathological study. Ann Rheum Dis 2010; 69: 193-7.
    • (2010) Ann Rheum Dis , vol.69 , pp. 193-197
    • Smith, V.1    Van Praet, J.T.2    Vandooren, B.3
  • 50
    • 84871861496 scopus 로고    scopus 로고
    • Two-year results of an open pilot study of a 2-treatment course with rituximab in patients with early systemic sclerosis with diffuse skin involvement
    • SMITH V, PIETTE Y, van PRAET JT et al.: Two-year results of an open pilot study of a 2-treatment course with rituximab in patients with early systemic sclerosis with diffuse skin involvement. J Rheumatol 2013; 40: 52-7.
    • (2013) J Rheumatol , vol.40 , pp. 52-57
    • Smith, V.1    Piette, Y.2    van Praet, J.T.3
  • 51
    • 85006306767 scopus 로고    scopus 로고
    • Effects of rituximab therapy on elastic properties of vascular wall in patients with progressive systemic sclerosis
    • [Epub ahead of print]
    • MASLYANSKIY AL, LAPIN SV, KOLESOVA EP et al.: Effects of rituximab therapy on elastic properties of vascular wall in patients with progressive systemic sclerosis. Clin Exp Rheumatol 2014. [Epub ahead of print]
    • (2014) Clin Exp Rheumatol
    • Maslyanskiy, A.L.1    Lapin, S.V.2    Kolesova, E.P.3
  • 52
    • 84865814629 scopus 로고    scopus 로고
    • Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy
    • KEIR GJ, MAHER TM, HANSELL DM et al.: Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy. Eur Respir J 2012; 40: 641-8.
    • (2012) Eur Respir J , vol.40 , pp. 641-648
    • Keir, G.J.1    Maher, T.M.2    Hansell, D.M.3
  • 53
    • 0034038720 scopus 로고    scopus 로고
    • Original article skin score decrease in systemic sclerosis patients treated with intravenous immunoglobulin - a preliminary report
    • LEVY Y, SHERER Y, LANGEVITZ P et al.: Original article skin score decrease in systemic sclerosis patients treated with intravenous immunoglobulin - a preliminary report 2000: 207-11.
    • , vol.2000 , pp. 207-211
    • Levy, Y.1    Sherer, Y.2    Langevitz, P.3
  • 54
    • 34347263723 scopus 로고    scopus 로고
    • Intravenous immunoglobulins improve the function and ameliorate joint involvement in systemic sclerosis: a pilot study
    • NACCI F, RIGHI A, CONFORTI ML et al.: Intravenous immunoglobulins improve the function and ameliorate joint involvement in systemic sclerosis: a pilot study. Ann Rheum Dis 2007; 66: 977-9.
    • (2007) Ann Rheum Dis , vol.66 , pp. 977-979
    • Nacci, F.1    Righi, A.2    Conforti, M.L.3
  • 55
    • 1542343965 scopus 로고    scopus 로고
    • Intravenous immunoglobulin modulates cutaneous involvement and reduces skin fibrosis in systemic sclerosis: an open-label study
    • LEVY Y, AMITAL H, LANGEVITZ P et al.: Intravenous immunoglobulin modulates cutaneous involvement and reduces skin fibrosis in systemic sclerosis: an open-label study. Arthritis Rheum 2004; 50: 1005-7.
    • (2004) Arthritis Rheum , vol.50 , pp. 1005-1007
    • Levy, Y.1    Amital, H.2    Langevitz, P.3
  • 56
    • 84883794316 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial: intravenous immunoglobulin treatment in patients with diffuse cutaneous systemic sclerosis
    • TAKEHARA K, IHN H, SATO S: A randomized, double-blind, placebo-controlled trial: intravenous immunoglobulin treatment in patients with diffuse cutaneous systemic sclerosis. Clin Exp Rheumatol 2013; 31: S151-6.
    • (2013) Clin Exp Rheumatol , vol.31
    • Takehara, K.1    Ihn, H.2    Sato, S.3
  • 57
    • 84889677536 scopus 로고    scopus 로고
    • Treatment of diffuse systemic sclerosis with hyperimmune caprine serum (AIMSPRO): a phase II double-blind placebo-controlled trial
    • QUILLINAN NP, McINTOSH D, VERNES J, HAQ S, DENTON CP: Treatment of diffuse systemic sclerosis with hyperimmune caprine serum (AIMSPRO): a phase II double-blind placebo-controlled trial. Ann Rheum Dis 2014; 73: 56-61.
    • (2014) Ann Rheum Dis , vol.73 , pp. 56-61
    • Quillinan, N.P.1    Mcintosh, D.2    Vernes, J.3    Haq, S.4    Denton, C.P.5
  • 58
    • 84898819359 scopus 로고    scopus 로고
    • Oral tolerance induction to type I collagen significantly reduces the skin score in patients with diffuse systemic sclerosis with late-phase disease. Results of a NIAMS/NIAID multicentre phase II placebo controlled double blind clinical trial [abstract]
    • Presentation number L28
    • POSTLETHWAITE AE, FURST DE, WONG WK et al.: Oral tolerance induction to type I collagen significantly reduces the skin score in patients with diffuse systemic sclerosis with late-phase disease. Results of a NIAMS/NIAID multicentre phase II placebo controlled double blind clinical trial [abstract]. ACR Annual Meeting 2005. Presentation number L28.
    • ACR Annual Meeting 2005
    • Postlethwaite, A.E.1    Furst, D.E.2    Wong, W.K.3
  • 59
    • 0028054192 scopus 로고
    • Therapy for severe interstitial lung disease in systemic sclerosis. A retrospective study
    • STEEN VD, LANZ JK, CONTE C, OWENS GR, MEDSGER TA: Therapy for severe interstitial lung disease in systemic sclerosis. A retrospective study. Arthritis Rheum 1994; 37: 1290-6.
    • (1994) Arthritis Rheum , vol.37 , pp. 1290-1296
    • Steen, V.D.1    Lanz, J.K.2    Conte, C.3    Owens, G.R.4    Medsger, T.A.5
  • 61
    • 4444309487 scopus 로고    scopus 로고
    • Treatment of early diffuse cutaneous systemic sclerosis patients in Japan by low-dose corticosteroids for skin involvement
    • TAKEHARA K: Treatment of early diffuse cutaneous systemic sclerosis patients in Japan by low-dose corticosteroids for skin involvement. Clin Exp Rheumatol 2004; 22: S87-9.
    • (2004) Clin Exp Rheumatol , vol.22
    • Takehara, K.1
  • 63
    • 0031684342 scopus 로고    scopus 로고
    • Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis
    • STEEN VD, MEDSGER TA: Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis. Arthritis Rheum 1998; 41: 1613-9.
    • (1998) Arthritis Rheum , vol.41 , pp. 1613-1619
    • Steen, V.D.1    Medsger, T.A.2
  • 64
    • 0036845156 scopus 로고    scopus 로고
    • Predictors and outcomes of scleroderma renal crisis: the high-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial
    • DeMARCO PJ, WEISMAN MH, SEIBOLD JR et al.: Predictors and outcomes of scleroderma renal crisis: the high-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial. Arthritis Rheum 2002; 46: 2983-9.
    • (2002) Arthritis Rheum , vol.46 , pp. 2983-2989
    • Demarco, P.J.1    Weisman, M.H.2    Seibold, J.R.3
  • 65
    • 34548013337 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study
    • NASH RA, MCSWEENEY PA, CROFFORD LJ et al.: High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study 2007; 110: 1388-96.
    • (2007) , vol.110 , pp. 1388-1396
    • Nash, R.A.1    Mcsweeney, P.A.2    Crofford, L.J.3
  • 66
    • 84883776313 scopus 로고    scopus 로고
    • Glucocorticoids in systemic sclerosis: weighing the benefits and risks - a systematic review
    • IUDICI M, van der GOES MC, VALENTINI G, BIJLSMA JWJ: Glucocorticoids in systemic sclerosis: weighing the benefits and risks - a systematic review. Clin Exp Rheumatol 2013; 31: 157-65.
    • (2013) Clin Exp Rheumatol , vol.31 , pp. 157-165
    • Iudici, M.1    van der Goes, M.C.2    Valentini, G.3    Bijlsma, J.W.J.4
  • 67
    • 73649119523 scopus 로고    scopus 로고
    • Observational study of treatment outcome in early diffuse cutaneous systemic sclerosis
    • HERRICK AL, LUNT M, WHIDBY N et al.: Observational study of treatment outcome in early diffuse cutaneous systemic sclerosis. J Rheumatol 2010; 37: 116-24.
    • (2010) J Rheumatol , vol.37 , pp. 116-124
    • Herrick, A.L.1    Lunt, M.2    Whidby, N.3
  • 68
    • 0037370821 scopus 로고    scopus 로고
    • Treatment of cutaneous calcinosis in limited systemic sclerosis with minocycline
    • ROBERTSON LP, MARSHALL RW, HICKLING P: Treatment of cutaneous calcinosis in limited systemic sclerosis with minocycline. Ann Rheum Dis 2003; 62: 267-9.
    • (2003) Ann Rheum Dis , vol.62 , pp. 267-269
    • Robertson, L.P.1    Marshall, R.W.2    Hickling, P.3
  • 69
    • 1042290310 scopus 로고    scopus 로고
    • Minocycline is not effective in systemic sclerosis: results of an open-label multicenter trial
    • MAYES MD, O'DONNELL D, ROTHFIELD NF, CSUKA ME: Minocycline is not effective in systemic sclerosis: results of an open-label multicenter trial. Arthritis Rheum 2004; 50: 553-7.
    • (2004) Arthritis Rheum , vol.50 , pp. 553-557
    • Mayes, M.D.1    O'donnell, D.2    Rothfield, N.F.3    Csuka, M.E.4
  • 70
    • 14044261363 scopus 로고    scopus 로고
    • Calcium channel blockers for primary Raynaud's phenomenon: a meta-analysis
    • (Oxford)
    • THOMPSON AE, POPE JE: Calcium channel blockers for primary Raynaud's phenomenon: a meta-analysis. Rheumatology (Oxford) 2005; 44: 145-50.
    • (2005) Rheumatology , vol.44 , pp. 145-150
    • Thompson, A.E.1    Pope, J.E.2
  • 71
    • 0034794451 scopus 로고    scopus 로고
    • Treatment of Raynaud's phenomenon with the selective serotonin reuptake inhibitor fluoxetine
    • (Oxford)
    • COLEIRO B, MARSHALL SE, DENTON CP et al.: Treatment of Raynaud's phenomenon with the selective serotonin reuptake inhibitor fluoxetine. Rheumatology (Oxford) 2001; 40: 1038-43.
    • (2001) Rheumatology , vol.40 , pp. 1038-1043
    • Coleiro, B.1    Marshall, S.E.2    Denton, C.P.3
  • 72
    • 0033511724 scopus 로고    scopus 로고
    • Losartan therapy for Raynaud's phenomenon and scleroderma: clinical and biochemical findings in a fifteen-week, randomized, parallel-group, controlled trial
    • DZIADZIO M, DENTON CP, SMITH R et al.: Losartan therapy for Raynaud's phenomenon and scleroderma: clinical and biochemical findings in a fifteen-week, randomized, parallel-group, controlled trial. Arthritis Rheum 1999; 42: 2646-55.
    • (1999) Arthritis Rheum , vol.42 , pp. 2646-2655
    • Dziadzio, M.1    Denton, C.P.2    Smith, R.3
  • 73
    • 0036733462 scopus 로고    scopus 로고
    • Prevention of vascular damage in scleroderma with angiotensin-converting enzyme (ACE) inhibition
    • (Oxford)
    • MADDISON P: Prevention of vascular damage in scleroderma with angiotensin-converting enzyme (ACE) inhibition. Rheumatology (Oxford) 2002; 41: 965-71.
    • (2002) Rheumatology , vol.41 , pp. 965-971
    • Maddison, P.1
  • 74
    • 10444270963 scopus 로고    scopus 로고
    • Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist
    • KORN JH, MAYES M, MATUCCI-CERINIC M et al.: Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist. Arthritis Rheum 2004; 50: 3985-93.
    • (2004) Arthritis Rheum , vol.50 , pp. 3985-3993
    • Korn, J.H.1    Mayes, M.2    Matucci-Cerinic, M.3
  • 75
    • 78650678451 scopus 로고    scopus 로고
    • Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial
    • MATUCCI-CERINIC M, DENTON CP, FURST DE et al.: Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial. Ann Rheum Dis 2011; 70: 32-8.
    • (2011) Ann Rheum Dis , vol.70 , pp. 32-38
    • Matucci-Cerinic, M.1    Denton, C.P.2    Furst, D.E.3
  • 76
    • 79953696248 scopus 로고    scopus 로고
    • Modified-release sildenafil reduces Raynaud's phenomenon attack frequency in limited cutaneous systemic sclerosis
    • HERRICK AL, van den HOOGEN F, GABRIELLI A et al.: Modified-release sildenafil reduces Raynaud's phenomenon attack frequency in limited cutaneous systemic sclerosis. Arthritis Rheum 2011; 63: 775-82.
    • (2011) Arthritis Rheum , vol.63 , pp. 775-782
    • Herrick, A.L.1    van den Hoogen, F.2    Gabrielli, A.3
  • 77
    • 79959736094 scopus 로고    scopus 로고
    • Effectiveness of interventions for secondary Raynaud's phenomenon: a systematic review
    • HUISSTEDE BM, HOOGVLIET P, PAULIS WD et al.: Effectiveness of interventions for secondary Raynaud's phenomenon: a systematic review. Arch Phys Med Rehabil 2011; 92: 1166-80.
    • (2011) Arch Phys Med Rehabil , vol.92 , pp. 1166-1180
    • Huisstede, B.M.1    Hoogvliet, P.2    Paulis, W.D.3
  • 78
    • 61649118817 scopus 로고    scopus 로고
    • MQX-503, a novel formulation of nitroglycerin, improves the severity of Raynaud's phenomenon: a randomized, controlled trial
    • CHUNG L, SHAPIRO L, FIORENTINO D et al.: MQX-503, a novel formulation of nitroglycerin, improves the severity of Raynaud's phenomenon: a randomized, controlled trial. Arthritis Rheum 2009; 60: 870-7.
    • (2009) Arthritis Rheum , vol.60 , pp. 870-877
    • Chung, L.1    Shapiro, L.2    Fiorentino, D.3
  • 80
    • 44449152061 scopus 로고    scopus 로고
    • Interstitial lung disease in systemic sclerosis: a simple staging system
    • GOH NSL, DESAI SR, VEERARAGHAVAN S et al.: Interstitial lung disease in systemic sclerosis: a simple staging system. Am J Respir Crit Care Med 2008; 177: 1248-54.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 1248-1254
    • Goh, N.S.L.1    Desai, S.R.2    Veeraraghavan, S.3
  • 81
    • 84871595397 scopus 로고    scopus 로고
    • The evolving pharmacotherapy of pulmonary fibrosis
    • LOTA HK, WELLS AU: The evolving pharmacotherapy of pulmonary fibrosis. Expert Opin Pharmacother 2013; 14: 79-89.
    • (2013) Expert Opin Pharmacother , vol.14 , pp. 79-89
    • Lota, H.K.1    Wells, A.U.2
  • 82
    • 28144459814 scopus 로고    scopus 로고
    • High-dose acetylcysteine in idiopathic pulmonary fibrosis
    • DEMEDTS M, BEHR J, BUHL R et al.: High-dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med 2005; 353: 2229-42.
    • (2005) N Engl J Med , vol.353 , pp. 2229-2242
    • Demedts, M.1    Behr, J.2    Buhl, R.3
  • 83
    • 70349634397 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of pulmonary hypertension
    • GALIÈ N, HOEPER MM, HUMBERT M et al.: Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 2009; 34: 1219-63.
    • (2009) Eur Respir J , vol.34 , pp. 1219-1263
    • Galiè, N.1    Hoeper, M.M.2    Humbert, M.3
  • 84
    • 84898779259 scopus 로고    scopus 로고
    • Continuous Intravenous Epoprostenol for Pulmonary Hypertension Due to the Scleroderma Spectrum of Disease
    • BADESCH DB, TAPSON VF, MCGOON MD et al.: Continuous Intravenous Epoprostenol for Pulmonary Hypertension Due to the Scleroderma Spectrum of Disease 2000; 132: 435-43.
    • (2000) , vol.132 , pp. 435-443
    • Badesch, D.B.1    Tapson, V.F.2    Mcgoon, M.D.3
  • 85
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study
    • CHANNICK RN, SIMONNEAU G, SITBON O et al.: Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 2001; 358: 1119-23.
    • (2001) Lancet , vol.358 , pp. 1119-1123
    • Channick, R.N.1    Simonneau, G.2    Sitbon, O.3
  • 86
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • RUBIN LJ, BADESCH DB, BARST RJ et al.: Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 2002; 346: 896-903.
    • (2002) N Engl J Med , vol.346 , pp. 896-903
    • Rubin, L.J.1    Badesch, D.B.2    Barst, R.J.3
  • 87
    • 33750344748 scopus 로고    scopus 로고
    • Bosentan treatment for pulmonary arterial hypertension related to connective tissue disease: a subgroup analysis of the pivotal clinical trials and their open-label extensions
    • DENTON CP, HUMBERT M, RUBIN L, BLACK CM: Bosentan treatment for pulmonary arterial hypertension related to connective tissue disease: a subgroup analysis of the pivotal clinical trials and their open-label extensions. Ann Rheum Dis 2006; 65: 1336-40.
    • (2006) Ann Rheum Dis , vol.65 , pp. 1336-1340
    • Denton, C.P.1    Humbert, M.2    Rubin, L.3    Black, C.M.4
  • 88
    • 46449124591 scopus 로고    scopus 로고
    • Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2
    • GALIÈ N, OLSCHEWSKI H, OUDIZ RJ et al.: Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2. Circulation 2008; 117: 3010-9.
    • (2008) Circulation , vol.117 , pp. 3010-3019
    • Galiè, N.1    Olschewski, H.2    Oudiz, R.J.3
  • 89
    • 26444534291 scopus 로고    scopus 로고
    • Sildenafil citrate therapy for pulmonary arterial hypertension
    • GALIÈ N, GHOFRANI HA, TORBICKI A et al.: Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl J Med 2005; 353: 2148-57.
    • (2005) N Engl J Med , vol.353 , pp. 2148-2157
    • Galiè, N.1    Ghofrani, H.A.2    Torbicki, A.3
  • 90
    • 67649523052 scopus 로고    scopus 로고
    • Tadalafil therapy for pulmonary arterial hypertension
    • GALIÈ N, BRUNDAGE BH, GHOFRANI HA et al.: Tadalafil therapy for pulmonary arterial hypertension. Circulation 2009; 119: 2894-903.
    • (2009) Circulation , vol.119 , pp. 2894-2903
    • Galiè, N.1    Brundage, B.H.2    Ghofrani, H.A.3
  • 91
    • 84880721470 scopus 로고    scopus 로고
    • Riociguat for the treatment of pulmonary arterial hypertension
    • GHOFRANI H-A, GALIÈ N, GRIMMINGER F et al.: Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 2013; 369: 330-40.
    • (2013) N Engl J Med , vol.369 , pp. 330-340
    • Ghofrani, H.-A.1    Galiè, N.2    Grimminger, F.3
  • 92
    • 84874948946 scopus 로고    scopus 로고
    • Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study
    • HOEPER MM, BARST RJ, BOURGE RC et al.: Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study. Circulation 2013; 127: 1128-38.
    • (2013) Circulation , vol.127 , pp. 1128-1138
    • Hoeper, M.M.1    Barst, R.J.2    Bourge, R.C.3
  • 93
    • 0028081921 scopus 로고
    • Acute renal failure occurring in scleroderma treated with cyclosporin A: a report of three cases
    • DENTON CP, SWENY P, ABDULLA A, BLACK CM: Acute renal failure occurring in scleroderma treated with cyclosporin A: a report of three cases. Br J Rheumatol 1994; 33: 90-2.
    • (1994) Br J Rheumatol , vol.33 , pp. 90-92
    • Denton, C.P.1    Sweny, P.2    Abdulla, A.3    Black, C.M.4
  • 94
    • 0025152770 scopus 로고
    • Outcome of renal crisis in systemic sclerosis: relation to availability of angiotensin converting enzyme (ACE) inhibitors
    • STEEN VD, COSTANTINO JP, SHAPIRO AP, MEDSGER TA: Outcome of renal crisis in systemic sclerosis: relation to availability of angiotensin converting enzyme (ACE) inhibitors. Ann Intern Med 1990; 113: 352-7.
    • (1990) Ann Intern Med , vol.113 , pp. 352-357
    • Steen, V.D.1    Costantino, J.P.2    Shapiro, A.P.3    Medsger, T.A.4
  • 95
    • 34547822481 scopus 로고    scopus 로고
    • Scleroderma renal crisis: patient characteristics and long-term outcomes
    • PENN H, HOWIE AJ, KINGDON EJ et al.: Scleroderma renal crisis: patient characteristics and long-term outcomes. QJM 2007; 100: 485-94.
    • (2007) QJM , vol.100 , pp. 485-494
    • Penn, H.1    Howie, A.J.2    Kingdon, E.J.3
  • 96
    • 0038799774 scopus 로고    scopus 로고
    • Natural history of systemic sclerosis and the assessment of disease activity, severity, functional status, and psychologic well-being
    • MEDSGER TA: Natural history of systemic sclerosis and the assessment of disease activity, severity, functional status, and psychologic well-being. Rheum Dis Clin North Am 2003; 29: 255-73.
    • (2003) Rheum Dis Clin North Am , vol.29 , pp. 255-273
    • Medsger, T.A.1
  • 98
    • 0035003217 scopus 로고    scopus 로고
    • European multicentre study to define disease activity criteria for systemic sclerosis. I. Clinical and epidemiological features of 290 patients from 19 centres
    • Della ROSSA A, VALENTINI G, BOMBARDIERI S et al.: European multicentre study to define disease activity criteria for systemic sclerosis. I. Clinical and epidemiological features of 290 patients from 19 centres. Ann Rheum Dis 2001; 60: 585-91.
    • (2001) Ann Rheum Dis , vol.60 , pp. 585-591
    • Della Rossa, A.1    Valentini, G.2    Bombardieri, S.3
  • 99
    • 0035020571 scopus 로고    scopus 로고
    • European multicentre study to define disease activity criteria for systemic sclerosis. II. Identification of disease activity variables and development of preliminary activity indexes
    • VALENTINI G, Della ROSSA A, BOMBARDIERI S et al.: European multicentre study to define disease activity criteria for systemic sclerosis. II. Identification of disease activity variables and development of preliminary activity indexes. Ann Rheum Dis 2001; 60: 592-8.
    • (2001) Ann Rheum Dis , vol.60 , pp. 592-598
    • Valentini, G.1    Della Rossa, A.2    Bombardieri, S.3
  • 100
    • 0042508746 scopus 로고    scopus 로고
    • European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. III. Assessment of the construct validity of the preliminary activity criteria
    • VALENTINI G, BENCIVELLI W, BOMBARDIERI S et al.: European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. III. Assessment of the construct validity of the preliminary activity criteria. Ann Rheum Dis 2003; 62: 901-3.
    • (2003) Ann Rheum Dis , vol.62 , pp. 901-903
    • Valentini, G.1    Bencivelli, W.2    Bombardieri, S.3
  • 101
    • 77953484773 scopus 로고    scopus 로고
    • Construct validity evaluation of the European Scleroderma Study Group activity index, and investigation of possible new disease activity markers in systemic sclerosis
    • (Oxford)
    • MINIER T, NAGY Z, BÁLINT Z et al.: Construct validity evaluation of the European Scleroderma Study Group activity index, and investigation of possible new disease activity markers in systemic sclerosis. Rheumatology (Oxford) 2010; 49: 1133-45.
    • (2010) Rheumatology , vol.49 , pp. 1133-1145
    • Minier, T.1    Nagy, Z.2    Bálint, Z.3
  • 102
    • 0344980376 scopus 로고    scopus 로고
    • A disease severity scale for systemic sclerosis: development and testing
    • MEDSGER TA, SILMAN AJ, STEEN VD et al.: A disease severity scale for systemic sclerosis: development and testing. J Rheumatol 1999; 26: 2159-67.
    • (1999) J Rheumatol , vol.26 , pp. 2159-2167
    • Medsger, T.A.1    Silman, A.J.2    Steen, V.D.3
  • 103
    • 0030829260 scopus 로고    scopus 로고
    • The value of the Health Assessment Questionnaire and special patient-generated scales to demonstrate change in systemic sclerosis patients over time
    • STEEN VD, MEDSGER TA: The value of the Health Assessment Questionnaire and special patient-generated scales to demonstrate change in systemic sclerosis patients over time. Arthritis Rheum 1997; 40: 1984-91.
    • (1997) Arthritis Rheum , vol.40 , pp. 1984-1991
    • Steen, V.D.1    Medsger, T.A.2
  • 104
    • 34447323600 scopus 로고    scopus 로고
    • Using a self-reported functional score to assess disease progression in systemic sclerosis
    • (Oxford)
    • SEREDNICKA K, SMYTH AE, BLACK CM, DENTON CP: Using a self-reported functional score to assess disease progression in systemic sclerosis. Rheumatology (Oxford) 2007; 46: 1107-10.
    • (2007) Rheumatology , vol.46 , pp. 1107-1110
    • Serednicka, K.1    Smyth, A.E.2    Black, C.M.3    Denton, C.P.4
  • 106
    • 35348860345 scopus 로고    scopus 로고
    • Development of a preliminary scleroderma gastrointestinal tract 1.0 quality of life instrument
    • KHANNA D, HAYS RD, PARK GS et al.: Development of a preliminary scleroderma gastrointestinal tract 1.0 quality of life instrument. Arthritis Rheum 2007; 57: 1280-6.
    • (2007) Arthritis Rheum , vol.57 , pp. 1280-1286
    • Khanna, D.1    Hays, R.D.2    Park, G.S.3
  • 107
    • 69749083926 scopus 로고    scopus 로고
    • Reliability and validity of the University of California. Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument
    • KHANNA D, HAYS RD, MARANIAN P et al.: Reliability and validity of the University of California, Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument. Arthritis Rheum 2009; 61: 1257-63.
    • (2009) Arthritis Rheum , vol.61 , pp. 1257-1263
    • Khanna, D.1    Hays, R.D.2    Maranian, P.3
  • 108
    • 36749038390 scopus 로고    scopus 로고
    • Development and validation of a scale for mouth handicap in systemic sclerosis: the Mouth Handicap in Systemic Sclerosis scale
    • MOUTHON L, RANNOU F, BÉREZNÉ A et al.: Development and validation of a scale for mouth handicap in systemic sclerosis: the Mouth Handicap in Systemic Sclerosis scale. Ann Rheum Dis 2007; 66: 1651-5.
    • (2007) Ann Rheum Dis , vol.66 , pp. 1651-1655
    • Mouthon, L.1    Rannou, F.2    Bérezné, A.3
  • 109
    • 84867599718 scopus 로고    scopus 로고
    • Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United Kingdom and Ireland
    • LING Y, JOHNSON MK, KIELY DG et al.: Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United Kingdom and Ireland. Am J Respir Crit Care Med 2012; 186: 790-6.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 790-796
    • Ling, Y.1    Johnson, M.K.2    Kiely, D.G.3
  • 110
    • 0036746069 scopus 로고    scopus 로고
    • Measuring disease activity and functional status in patients with scleroderma and Raynaud's phenomenon
    • MERKEL PA, HERLYN K, MARTIN RW et al.: Measuring disease activity and functional status in patients with scleroderma and Raynaud's phenomenon. Arthritis Rheum 2002; 46: 2410-20.
    • (2002) Arthritis Rheum , vol.46 , pp. 2410-2420
    • Merkel, P.A.1    Herlyn, K.2    Martin, R.W.3
  • 111
    • 70450202550 scopus 로고    scopus 로고
    • Measures of response in clinical trials of systemic sclerosis: the Combined Response Index for Systemic Sclerosis (CRISS) and Outcome Measures in Pulmonary Arterial Hypertension related to Systemic Sclerosis (EPOSS)
    • KHANNA D, DISTLER O, AVOUAC J et al.: Measures of response in clinical trials of systemic sclerosis: the Combined Response Index for Systemic Sclerosis (CRISS) and Outcome Measures in Pulmonary Arterial Hypertension related to Systemic Sclerosis (EPOSS). J Rheumatol 2009; 36: 2356-61.
    • (2009) J Rheumatol , vol.36 , pp. 2356-2361
    • Khanna, D.1    Distler, O.2    Avouac, J.3
  • 112
    • 84898775777 scopus 로고    scopus 로고
    • Prediction of pulmonary complications and long term survival in systemic sclerosis
    • [Epub ahead of print]
    • NIHTYANOVA SI, SCHREIBER BE, ONG VH et al.: Prediction of pulmonary complications and long term survival in systemic sclerosis. Arthritis Rheumatol 2014 [Epub ahead of print].
    • (2014) Arthritis Rheumatol
    • Nihtyanova, S.I.1    Schreiber, B.E.2    Ong, V.H.3
  • 113
    • 84861478146 scopus 로고    scopus 로고
    • The impact of cardiopulmonary manifestations on the mortality of SSc: a systematic review and meta-analysis of observational studies
    • (Oxford)
    • KOMÓCSI A, VOROBCSUK A, FALUDI R et al.: The impact of cardiopulmonary manifestations on the mortality of SSc: a systematic review and meta-analysis of observational studies. Rheumatology (Oxford) 2012; 51: 1027-36.
    • (2012) Rheumatology , vol.51 , pp. 1027-1036
    • Komócsi, A.1    Vorobcsuk, A.2    Faludi, R.3
  • 114
    • 77950261786 scopus 로고    scopus 로고
    • Improved survival in systemic sclerosis is associated with better ascertainment of internal organ disease: a retrospective cohort study
    • NIHTYANOVA SI, TANG EC, COGHLAN JG, WELLS AU, BLACK CM, DENTON CP: Improved survival in systemic sclerosis is associated with better ascertainment of internal organ disease: a retrospective cohort study. QJM 2010; 103: 109-15.
    • (2010) QJM , vol.103 , pp. 109-115
    • Nihtyanova, S.I.1    Tang, E.C.2    Coghlan, J.G.3    Wells, A.U.4    Black, C.M.5    Denton, C.P.6


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