Predictors of exercise-induced oxygen desaturation in systemic sclerosis patients with interstitial lung disease

Respiratory Care

Volumn 59, Issue 1, 2014, Pages 75-80

  Someya, Fujiko ^a   Mugii, Naoki ^b   Hasegawa, Minoru ^a   Yahata, Tetsutarou ^b   Nakagawa, Takao ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY HOSPITAL   (Japan)

Author keywords

6 min walk test; Interstitial lung disease; Oxygen saturation; Pulmonary arterial hypertension; Pulmonary function; Systemic sclerosis

Indexed keywords

ADULT; ARTICLE; EXERCISE INDUCED OXYGEN DESATURATION; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG DIFFUSION CAPACITY; MAJOR CLINICAL STUDY; MALE; OXYGEN DESATURATION; OXYGEN SATURATION; PEAK EXPIRATORY FLOW; PREDICTION; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SYSTEMIC SCLEROSIS; TOTAL LUNG CAPACITY; TRANSTHORACIC ECHOCARDIOGRAPHY; WALKING;

6-MIN WALK TEST; INTERSTITIAL LUNG DISEASE; OXYGEN SATURATION; PULMONARY ARTERIAL HYPERTENSION; PULMONARY FUNCTION; SYSTEMIC SCLEROSIS;

AGED; AREA UNDER CURVE; CARBON MONOXIDE; EXERCISE TEST; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LUNG DISEASES, INTERSTITIAL; MALE; MIDDLE AGED; OXYGEN; PULMONARY DIFFUSING CAPACITY; ROC CURVE; SCLERODERMA, SYSTEMIC; TOTAL LUNG CAPACITY; VITAL CAPACITY;

EID: 84891420804     PISSN: 00201324     EISSN: 19433654     Source Type: Journal    
DOI: 10.4187/respcare.02452     Document Type: Article

References (22)

1. Lama VN, Flaherty KR, Toews GB, Colby TV, Travis WD, Long Q, et al. Prognostic value of desaturation during a 6-minute walk test in idiopathic interstitial pneumonia. Am J Respir Crit Care Med 2003; 168(9):1084-1090.
2. Wallaert B, Wemeau-Stervinou L, Salleron J, Tillie-Leblond I, Perez T. Do we need exercise tests to detect gas exchange impairment in fibrotic idiopathic interstitial pneumonias? Pulm Med 2012;2012: 657180. DOI: 10.1155/2012/657180.
3. Wemeau-Stervinou L, Perez T, Murphy C, Polge AS, Wallaert B. Lung capillary blood volume and membrane diffusion in idiopathic interstitial pneumonia. Respir Med 2012;106(4):564-570.
4. Garin MC, Highland KB, Silver RM, Strange C. Limitations to the 6-minute walk test in interstitial lung disease and pulmonary hypertension in scleroderma. J Rheumatol 2009;36(2):330-336.
5. Alkotob ML, Soltani P, Sheatt MA, Katsetos MC, Rothfield N, Hager WD, et al. Reduced exercise capacity and stress-induced pulmonary hypertension in patients with scleroderma. Chest 2006;130(1): 176-181.
6. Trad S, Huong DLT, Frances C, Wechsler B, Cacoub P, Costedoat N, et al. Impaired carbon monoxide diffusing capacity as a marker of limited systemic sclerosis. Eur J Intern Med 2011;22(6):e80-e86.
7. Villalba WO, Sampaio-Barros PD, Pereira MC, Cerqueira EMFP, Leme Jr CA, Marques-Neto JF, Paschoal IA. Six-minute walk test for the evaluation of pulmonary disease severity in scleroderma patients. Chest 2007;131(1):217-222.
8. Mugii N, Someya F, Hasegawa M. Reduced hypoxia risk in a systemic sclerosis patient with interstitial lung disease after long-term pulmonary rehabilitation. Clin Med Insights Case Rep 2011;4:53-56.
9. Wilsher M, Good N, Hopkins R, Young P, Milne D, Gibson A. et al. The six-minute walk test using forehead oximetry is reliable in the assessment of scleroderma lung disease. Respirology 2012;17(4): 647-652.
10. Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, et al. Interpretative strategies for lung function tests. Eur Respir J 2005;26(5):948-968.
11. Meune C, Avouac J, Wahbi K, Cabanes L, Wipff J, Mouthon L. et al. Cardiac involvement in systemic sclerosis assessed by tissue-Doppler echocardiography during routine care: a controlled study of 100 consecutive patients. Arthritis Rheum 2008;58(6):1803-1809.
12. Schachna L, Wigley FM, Chang B, White B, Wise RA, Gelber AC. Age and risk of pulmonary arterial hypertension in scleroderma. Chest 2003;124(6):2098-2104.
13. American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment: international consensus statement. Am J Respir Care Med 2000;161(2):646-664.
14. Hallstrand TS, Boitano LJ, Johnson WC, SPada CA, Hayes JG, Raghu G. The timed walk test as a measure of severity and survival in idiopathic pulmonary fibrosis. Eur Respir J 2005;25(1):96-103.
15. Pimenta SP, da Rocha RB, Baldi BG, Kawassaki AM, Kairalla RA, Carvalho CRR. Desaturation-distance ratio: a new concept for a functional assessment of interstitial lung diseases. Clinics 2010;65(9): 841-846.
16. Steen VD, Graham G, Conte C, Owens G, Medsger TA Jr. Isolated diffusing capacity reduction in systemic sclerosis. Arthritis Rheum 1992;35(7):765-770.
17. Dumitrescu D, Oudiz RJ, Karpouzas G, Hovanesyan A, Jayasinghe A, Hansen JE, et al. Developing pulmonary vasculopathy in systemic sclerosis, detected with non-invasive cardiopulmonary exercise testing. PLoS One 2010;5(12):e14293. DOI: 10.1371/journal. pone.0014293.
18. Koh ET, Lee P, Gladman DD, Abu-Shakra M. Pulmonary hypertension in systemic sclerosis: an analysis of 17 patients. Br J Rheumatol 1996;35(10):989-993.
19. D'Alto M, Ghio S, D'Andrea A, Pazzano AS, Argiento P, Camporotondo R, et al. Inappropriate exercise-induced increase in pulmonary artery pressure in patients with systemic sclerosis. Heart 2011; 97(2):112-117.
20. Yasunobu Y, Oudiz RJ, Sun XG, Hansen JE, Wasserman K. Endtidal Pco2 abnormality and exercise limitation in patients with primary pulmonary hypertension. Chest 2005;127(5):1637-1646.
21. Fowler RM, Jenkins SC, Maiorana AJ, Garin RK, O'Driscoll G, Gabbay E: Measurement properties of the 6-min walk test in individuals with exercise-induced pulmonary arterial hypertension. Int Med J 2011;41(9):679-678.
22. Hashimoto A, Endo H, Kondo H, Hirohata S. Clinical features of 405 Japanese patients with systemic sclerosis. Mod Rheumatol 2012; 22(2):272-279.