Serious infections among adult medicaid beneficiaries with systemic lupus erythematosus and lupus nephritis

Arthritis and Rheumatology

Volumn 67, Issue 6, 2015, Pages 1577-1585

  Feldman, Candace H ^a,b   Hiraki, Linda T ^c   Winkelmayer, Wolfgang C ^d   Marty, Francisco M ^a   Franklin, Jessica M ^a   Kim, Seoyoung C ^a   Costenbader, Karen H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DEXAMETHASONE; HYDROCORTISONE; HYDROXYCHLOROQUINE; LEFLUNOMIDE; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLATE MOFETIL; MYCOPHENOLIC ACID; PREDNISONE; RITUXIMAB; TACROLIMUS; ANTIRHEUMATIC AGENT; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT;

ADULT; ALGORITHM; ARTICLE; CELLULITIS; COHORT ANALYSIS; CONTROLLED STUDY; CRYPTOCOCCOSIS; FEMALE; HUMAN; INCIDENCE; INFECTION RISK; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; MEDICAID; MORTALITY; PNEUMONIA; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; SOCIAL STATUS; SYSTEMIC LUPUS ERYTHEMATOSUS; ADOLESCENT; AFRICAN AMERICAN; CAUCASIAN; INFECTION; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; POISSON DISTRIBUTION; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SEX DIFFERENCE; STATISTICS AND NUMERICAL DATA; UNITED STATES; YOUNG ADULT;

ADOLESCENT; ADULT; AFRICAN AMERICANS; ANTIRHEUMATIC AGENTS; COHORT STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOCORTICOIDS; HUMANS; HYDROXYCHLOROQUINE; IMMUNOSUPPRESSIVE AGENTS; INFECTION; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MALE; MEDICAID; MIDDLE AGED; MULTIVARIATE ANALYSIS; POISSON DISTRIBUTION; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; UNITED STATES; YOUNG ADULT;

EID: 84929847781     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39070     Document Type: Article

References (48)

1. Zandman-Goddard G, Shoenfeld Y., Infections and SLE. Autoimmunity 2005; 38: 473-85.
2. Yuhara T, Takemura H, Akama T, Suzuki H, Yamane K, Kashiwagi H., Predicting infection in hospitalized patients with systemic lupus erythematosus. Intern Med 1996; 35: 629-36.
3. Gladman DD, Hussain F, Ibanez D, Urowitz MB., The nature and outcome of infection in systemic lupus erythematosus. Lupus 2002; 11: 234-9.
4. Bouza E, Moya JG, Munoz P., Infections in systemic lupus erythematosus and rheumatoid arthritis. Infect Dis Clin North Am 2001; 15: 335-61, vii.
5. Staples PJ, Gerding DN, Decker JL, Gordon RS Jr., Incidence of infection in systemic lupus erythematosus. Arthritis Rheum 1974; 17: 1-10.
6. Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P, et al., Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients. Medicine (Baltimore) 2003; 82: 299-308.
7. Yap DY, Tang CS, Ma MK, Lam MF, Chan TM., Survival analysis and causes of mortality in patients with lupus nephritis. Nephrol Dial Transplant 2012; 27: 3248-54.
8. Ginzler E, Diamond H, Kaplan D, Weiner M, Schlesinger M, Seleznick M., Computer analysis of factors influencing frequency of infection in systemic lupus erythematosus. Arthritis Rheum 1978; 21: 37-44.
9. Noel V, Lortholary O, Casassus P, Cohen P, Genereau T, Andre MH, et al., Risk factors and prognostic influence of infection in a single cohort of 87 adults with systemic lupus erythematosus. Ann Rheum Dis 2001; 60: 1141-4.
10. Zonana-Nacach A, Camargo-Coronel A, Yanez P, Sanchez L, Jimenez-Balderas FJ, Fraga A., Infections in outpatients with systemic lupus erythematosus: a prospective study. Lupus 2001; 10: 505-10.
11. Shyam C, Malaviya AN., Infection-related morbidity in systemic lupus erythematosus: a clinico-epidemiological study from northern India. Rheumatol Int 1996; 16: 1-3.
12. Ramos L, Lopez C, Gomez C, Mathurin S, Mateo A., Cutaneous cryptococcosis in a patient with systemic erythematous lupus. Mycoses 2001; 44: 419-21.
13. Chen HS, Tsai WP, Leu HS, Ho HH, Liou LB., Invasive fungal infection in systemic lupus erythematosus: an analysis of 15 cases and a literature review. Rheumatology (Oxford) 2007; 46: 539-44.
14. Chakravarty E, Michaud K, Katz R, Wolfe F., Increased incidence of herpes zoster among patients with systemic lupus erythematosus. Lupus 2013; 22: 238-44.
15. Nagasawa K, Yamauchi Y, Tada Y, Kusaba T, Niho Y, Yoshikawa H., High incidence of herpes zoster in patients with systemic lupus erythematosus: an immunological analysis. Ann Rheum Dis 1990; 49: 630-3.
16. Ramos-Casals M., Viruses and lupus: the viral hypothesis. Lupus 2008; 17: 163-5.
17. Tsai WP, Chen MH, Lee MH, Yu KH, Wu MW, Liou LB., Cytomegalovirus infection causes morbidity and mortality in patients with autoimmune diseases, particularly systemic lupus, in a Chinese population in Taiwan. Rheumatol Int 2012; 32: 2901-8.
18. Bosch X, Guilabert A, Pallares L, Cerveral R, Ramos-Casals M, Bove A, et al., Infections in systemic lupus erythematosus: a prospective and controlled study of 110 patients. Lupus 2006; 15: 584-9.
19. Henry J., Kaiser Family Foundation. The Kaiser Commission on Medicaid and the Uninsured. 2010. URL: http://files.kff.org/attachment/issue-brief-medicaid-moving-forward.
20. US Department of Health and Human Services, Administration on Aging, Administration for Community Living. A profile of older Americans: 2012. URL: http://www.aoa.gov/Aging-Statistics/Profile/2012/docs/2012profile.pdf.
21. Feldman CH, Hiraki LT, Liu J, Fischer MA, Solomon DH, Alarcon GS, et al., Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004. Arthritis Rheum 2013; 65: 753-63.
22. Hiraki LT, Feldman CH, Liu J, Alarcon GS, Fischer MA, Winkelmayer WC, et al., Prevalence, incidence, and demographics of systemic lupus erythematosus and lupus nephritis from 2000 to 2004 among children in the US Medicaid beneficiary population. Arthritis Rheum 2012; 64: 2669-76.
23. Chibnik LB, Massarotti EM, Costenbader KH., Identification and validation of lupus nephritis cases using administrative data. Lupus 2010; 19: 741-3.
24. Schneeweiss S, Robicsek A, Scranton R, Zuckerman D, Solomon DH., Veteran's affairs hospital discharge databases coded serious bacterial infections accurately. J Clin Epidemiol 2007; 60: 397-409.
25. Erickson KF, Winkelmayer WC, Chertow GM, Bhattacharya J., Physician visits and 30-day hospital readmissions in patients receiving hemodialysis. J Am Soc Nephrol 2014; 25: 2079-87.
26. Centers for Medicare and Medicaid Services, Chronic Conditions Data Warehouse. Medicaid enrollment by race, 2001 -2010. URL: https://www.ccwdata.org/web/guest/medicaid-charts#a2-race-2001-2010.
27. Ward MM., Medical insurance, socioeconomic status, and age of onset of endstage renal disease in patients with lupus nephritis. J Rheumatol 2007; 34: 2024-7.
28. Ward MM., Development and testing of a systemic lupus-specific risk adjustment index for in-hospital mortality. J Rheumatol 2000; 27: 1408-13.
29. Abrahamowicz M, MacKenzie T, Esdaile JM., Time-dependent hazard ratio: modeling and hypothesis testing with application in lupus nephritis. J Am Stat Assoc 1996; 91: 1432-9.
30. Schneeweiss S, Setoguchi S, Weinblatt ME, Katz JN, Avorn J, Sax PE, et al., Anti-tumor necrosis factor α therapy and the risk of serious bacterial infections in elderly patients with rheumatoid arthritis. Arthritis Rheum 2007; 56: 1754-64.
31. Petri M., Infection in systemic lupus erythematosus. Rheum Dis Clin North Am 1998; 24: 423-56.
32. Klemperer P, Pollack A, Baehr G., Pathology of disseminated lupus erythematosus. Arch Pathol 1941; 32: 569-631.
33. Garred P, Voss A, Madsen HO, Junker P., Association of mannose-binding lectin gene variation with disease severity and infections in a population-based cohort of systemic lupus erythematosus patients. Genes Immun 2001; 2: 442-50.
34. Mok MY, Ip WK, Lau CS, Lo Y, Wong WH, Lau YL., Mannose-binding lectin and susceptibility to infection in Chinese patients with systemic lupus erythematosus. J Rheumatol 2007; 34: 1270-6.
35. Bultink IE, Hamann D, Seelen MA, Hart MH, Dijkmans BA, Daha MR, et al., Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosus. Arthritis Res Ther 2006; 8: R183.
36. Petri M, Genovese M., Incidence of and risk factors for hospitalizations in systemic lupus erythematosus: a prospective study of the Hopkins Lupus Cohort. J Rheumatol 1992; 19: 1559-65.
37. Pryor BD, Bologna SG, Kahl LE., Risk factors for serious infection during treatment with cyclophosphamide and high-dose corticosteroids for systemic lupus erythematosus. Arthritis Rheum 1996; 39: 1475-82.
38. Hellmann DB, Petri M, Whiting-O'Keefe Q., Fatal infections in systemic lupus erythematosus: the role of opportunistic organisms. Medicine (Baltimore) 1987; 66: 341-8.
39. Savarino A, Boelaert JR, Cassone A, Majori G, Cauda R., Effects of chloroquine on viral infections: an old drug against today's diseases? Lancet Infect Dis 2003; 3: 722-7.
40. Raoult D, Houpikian P, Tissot Dupont H, Riss JM, Arditi-Djiane J, Brouqui P., Treatment of Q fever endocarditis: comparison of 2 regimens containing doxycycline and ofloxacin or hydroxychloroquine. Arch Intern Med 1999; 159: 167-73.
41. Tan TC, Fang H, Magder LS, Petri MA., Differences between male and female systemic lupus erythematosus in a multiethnic population. J Rheumatol 2012; 39: 759-69.
42. Alarcon GS, McGwin G Jr, Bastian HM, Roseman J, Lisse J, Fessler BJ, et al, for the LUMINA Study Group. Systemic lupus erythematosus in three ethnic groups. VII [correction of VIII]. Predictors of early mortality in the LUMINA cohort. LUMINA Study Group. Arthritis Rheum 2001; 45: 191-202.
43. Feldman CH, Hiraki LT, Liu J, Fischer MA, Solomon DH, Alarcon GS, et al., Epidemiology and sociodemographics of systemic lupus erythematosus and lupus nephritis among US adults with Medicaid coverage, 2000-2004. Arthritis Rheum 2013; 65: 753-63.
44. Costenbader KH, Desai A, Alarcon GS, Hiraki LT, Shaykevich T, Brookhart MA, et al., Trends in the incidence, demographics, and outcomes of end-stage renal disease due to lupus nephritis in the US from 1995 to 2006. Arthritis Rheum 2011; 63: 1681-8.
45. Ward MM, Pyun E, Studenski S., Causes of death in systemic lupus erythematosus: long-term followup of an inception cohort. Arthritis Rheum 1995; 38: 1492-9.
46. Rubin LA, Urowitz MB, Gladman DD., Mortality in systemic lupus erythematosus: the bimodal pattern revisited. Q J Med 1985; 55: 87-98.
47. Abu-Shakra M, Urowitz MB, Gladman DD, Gough J., Mortality studies in systemic lupus erythematosus: results from a single center. I. Causes of death. J Rheumatol 1995; 22: 1259-64.
48. Gomez-Puerta JA, Barbhaiya M, Guan H, Feldman CH, Alarcon GS, Costenbader KH., Racial/ethnic variation in all-cause mortality among United States Medicaid recipients with systemic lupus erythematosus: a Hispanic and Asian paradox. Arthritis Rheumatol 2015; 67: 752-60.