Apocynin inhibits the upregulation of TGF-β1 expression and ROS production induced by TGF-β in skeletal muscle cells

Phytomedicine

Volumn 22, Issue 10, 2015, Pages 885-893

  Abrigo, Johanna ^a,b   Morales, María Gabriela ^a,b   Simon, Felipe ^a,b   Cabrera, Daniel ^c   Capua, Gabriella Di ^a,b   Cabello Verrugio, Claudio ^a,b  

^a UNIVERSIDAD ANDRÉS BELLO   (Chile)

^b Facultad de Medicina Universidad Andrés Bello   (Chile)

^c UNIVERSIDAD BERNARDO O'HIGGINS   (Chile)

Author keywords

Atrophy; NOX; ROS; Skeletal muscle; Smad; TGF 1

Indexed keywords

APOCYNIN; ATROGIN 1; OXIDOREDUCTASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; 6-(2-TERT-BUTYL-5-(6-METHYLPYRIDIN-2-YL)-1H-IMIDAZOL-4-YL)QUINOXALINE; ACETOPHENONE DERIVATIVE; BENZOPHENANTHRIDINE DERIVATIVE; CHELERYTHRINE; IMIDAZOLE DERIVATIVE; PROTEIN KINASE C; QUINOXALINE DERIVATIVE; SMAD2 PROTEIN, MOUSE; SMAD3 PROTEIN, MOUSE; TGFB1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE; IN VITRO STUDY; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG EFFECTS; METABOLISM; MOUSE;

PICRORHIZA KURROOA; SCROPHULARIACEAE;

ACETOPHENONES; ANIMALS; BENZOPHENANTHRIDINES; CELL LINE; IMIDAZOLES; MICE; MUSCLE FIBERS, SKELETAL; PROTEIN KINASE C; QUINOXALINES; REACTIVE OXYGEN SPECIES; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84937940815     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2015.06.011     Document Type: Article

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