Iterative experiment design guides the characterization of a light-inducible gene expression circuit

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 26, 2015, Pages 8148-8153

  Ruess, Jakob ^a,b   Parise, Francesca ^a   Milias Argeitis, Andreas ^a   Khammash, Mustafa ^a   Lygeros, John ^a  

^a ETH ZURICH   (Switzerland)

^b INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA   (Austria)

Author keywords

In vivo control; Light induced gene expression; Optimal experiment design; Parameter inference; Stochastic kinetic models

Indexed keywords

MESSENGER RNA; PHYTOCHROME B;

ARTICLE; CELL POPULATION; EXPERIMENT; FAR RED LIGHT; FLOW CYTOMETRY; FLUORESCENCE; GENE EXPRESSION; LIGHT; MOLECULAR BIOLOGY; NONHUMAN; POPULATION; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOCHASTIC MODEL; SYSTEMS BIOLOGY; GENE EXPRESSION REGULATION; MARKOV CHAIN;

GENE EXPRESSION REGULATION; LIGHT; STOCHASTIC PROCESSES; SYSTEMS BIOLOGY;

EID: 84937937458     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1423947112     Document Type: Article

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