Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 29, 2015, Pages E3883-E3892

  Wang, Yang ^a   Zhong, Huiling ^a   Xie, Xiaodan ^a   Chen, Crystal Y ^b   Huang, Dan ^b   Shen, Ling ^b   Zhang, Hui ^a   Chen, Zheng W ^b   Zeng, Gucheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

CD8+ T cells; lncRNA; Tuberculosis

Indexed keywords

GAMMA INTERFERON; LONG UNTRANSLATED RNA; TRANSCRIPTION FACTOR EZH2; TUMOR NECROSIS FACTOR ALPHA; CD244 PROTEIN, HUMAN; CHROMATIN; EZH2 PROTEIN, HUMAN; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE ANTIGEN; MONOCLONAL ANTIBODY; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN BINDING; SH2D1A PROTEIN, HUMAN; SH2D1B PROTEIN, HUMAN; SIGNAL PEPTIDE; TRANSCRIPTION FACTOR;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD244 GENE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHROMATIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPIGENETICS; GENE; GENE LOCUS; IMMUNOMODULATION; METHYLATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; TUBERCULOSIS; UPREGULATION; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; BIOLOGY; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECTS; GENE SILENCING; GENETIC EPIGENESIS; GENETICS; HEK293 CELL LINE; HUMAN; HUMAN GENOME; IMMUNITY; IMMUNOLOGY; METABOLISM; MOLECULAR EVOLUTION; NUCLEOTIDE SEQUENCE; SIGNAL TRANSDUCTION;

MUS; MYCOBACTERIUM TUBERCULOSIS;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; APOPTOSIS; CD8-POSITIVE T-LYMPHOCYTES; CHROMATIN; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; EPIGENESIS, GENETIC; EVOLUTION, MOLECULAR; GENE KNOCKDOWN TECHNIQUES; GENOME, HUMAN; HEK293 CELLS; HUMANS; IMMUNITY; INTERFERON-GAMMA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MODELS, BIOLOGICAL; POLYCOMB REPRESSIVE COMPLEX 2; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RNA, LONG NONCODING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84937935952     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1501662112     Document Type: Article

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