Membrane-bound IL-22 after de novo production in tuberculosis and anti-Mycobacterium tuberculosis effector function of IL-22+ CD4 + T cells

Journal of Immunology

Volumn 187, Issue 1, 2011, Pages 190-199

  Zeng, Gucheng ^a,b   Chen, Crystal Y ^a   Huang, Dan ^a   Yao, Shuyu ^a   Wang, Richard C ^a   Chen, Zheng W ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; INTERLEUKIN 22;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL IMMUNITY; CD4+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE MEMBRANE; MACACA; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE ACTIVATION; TUBERCULOSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELL COMMUNICATION; CELL DIFFERENTIATION; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKINS; INTRACELLULAR FLUID; LYMPHOCYTE ACTIVATION; MACACA MULATTA; MACROPHAGES, ALVEOLAR; MEMBRANE PROTEINS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; PROTEIN TRANSPORT; TUBERCULOSIS, PULMONARY;

EID: 79960396263     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1004129     Document Type: Article

References (42)

1. Zhou, L., M. M. Chong, and D. R. Littman. 2009. Plasticity of CD4+ T cell lineage differentiation. Immunity 30: 646-655.
2. Zhu, J., and W. E. Paul. 2008. CD4 T cells: fates, functions, and faults. Blood 112: 1557-1569.
3. Luci, C., A. Reynders, I. I. Ivanov, C. Cognet, L. Chiche, L. Chasson, J. Hardwigsen, E. Anguiano, J. Banchereau, D. Chaussabel, et al. 2009. Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat. Immunol. 10: 75-82.
4. Zenewicz, L. A., G. D. Yancopoulos, D. M. Valenzuela, A. J. Murphy, S. Stevens, and R. A. Flavell. 2008. Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease. Immunity 29: 947-957.
5. Cella, M., A. Fuchs, W. Vermi, F. Facchetti, K. Otero, J. K. Lennerz, J. M. Doherty, J. C. Mills, and M. Colonna. 2009. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457: 722-725.
6. Bettelli, E., T. Korn, M. Oukka, and V. K. Kuchroo. 2008. Induction and effector functions of T(H)17 cells. Nature 453: 1051-1057.
7. Andoh, A., Z. Zhang, O. Inatomi, S. Fujino, Y. Deguchi, Y. Araki, T. Tsujikawa, K. Kitoh, S. Kim-Mitsuyama, A. Takayanagi, et al. 2005. Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts. Gastroenterology 129: 969-984. (Pubitemid 41242688)
8. Ikeuchi, H., T. Kuroiwa, N. Hiramatsu, Y. Kaneko, K. Hiromura, K. Ueki, and Y. Nojima. 2005. Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum. 52: 1037-1046. (Pubitemid 40530109)
9. Zheng, Y., D. M. Danilenko, P. Valdez, I. Kasman, J. Eastham-Anderson, J. Wu, and W. Ouyang. 2007. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 445: 648-651. (Pubitemid 46232884)
10. Ma, H. L., S. Liang, J. Li, L. Napierata, T. Brown, S. Benoit, M. Senices, D. Gill, K. Dunussi-Joannopoulos, M. Collins, et al. 2008. IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J. Clin. Invest. 118: 597-607.
11. Wilson, M. S., C. G. Feng, D. L. Barber, F. Yarovinsky, A. W. Cheever, A. Sher, M. Grigg, M. Collins, L. Fouser, and T. A. Wynn. 2010. Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections. J. Immunol. 184: 4378-4390.
12. Zenewicz, L. A., G. D. Yancopoulos, D. M. Valenzuela, A. J. Murphy, M. Karow, and R. A. Flavell. 2007. Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity 27: 647-659.
13. Sugimoto, K., A. Ogawa, E. Mizoguchi, Y. Shimomura, A. Andoh, A. K. Bhan, R. S. Blumberg, R. J. Xavier, and A. Mizoguchi. 2008. IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. J. Clin. Invest. 118: 534-544.
14. Wolk, K., S. Kunz, E. Witte, M. Friedrich, K. Asadullah, and R. Sabat. 2004. IL-22 increases the innate immunity of tissues. Immunity 21: 241-254. (Pubitemid 39094053)
15. Liang, S. C., X. Y. Tan, D. P. Luxenberg, R. Karim, K. Dunussi-Joannopoulos, M. Collins, and L. A. Fouser. 2006. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203: 2271-2279.
16. Zheng, Y., P. A. Valdez, D. M. Danilenko, Y. Hu, S. M. Sa, Q. Gong, A. R. Abbas, Z. Modrusan, N. Ghilardi, F. J. de Sauvage, and W. Ouyang. 2008. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat. Med. 14: 282-289.
17. Aujla, S. J., Y. R. Chan, M. Zheng, M. Fei, D. J. Askew, D. A. Pociask, T. A. Reinhart, F. McAllister, J. Edeal, K. Gaus, et al. 2008. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med. 14: 275-281.
18. Wirth, T., F. Hildebrand, C. Allix-Béguec, F. Wölbeling, T. Kubica, K. Kremer, D. van Soolingen, S. Rüsch-Gerdes, C. Locht, S. Brisse, et al. 2008. Origin, spread and demography of the Mycobacterium tuberculosis complex. PLoS Pathog. 4: e1000160.
19. Kaufmann, S. H. 2001. How can immunology contribute to the control of tuberculosis? Nat. Rev. Immunol. 1: 20-30.
20. Qiu, L., D. Huang, C. Y. Chen, R. Wang, L. Shen, Y. Shen, R. Hunt, J. Estep, B. F. Haynes, W. R. Jacobs, Jr. et al. 2008. Severe tuberculosis induces unbalanced up-regulation of gene networks and overexpression of IL-22, MIP-1alpha, CCL27, IP-10, CCR4, CCR5, CXCR3, PD1, PDL2, IL-3, IFN-beta, TIM1, and TLR2 but low antigen-specific cellular responses. J. Infect. Dis. 198: 1514-1519.
21. Scriba, T. J., B. Kalsdorf, D. A. Abrahams, F. Isaacs, J. Hofmeister, G. Black, H. Y. Hassan, R. J. Wilkinson, G. Walzl, S. J. Gelderbloem, et al. 2008. Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response. J. Immunol. 180: 1962-1970.
22. Zeng, G., D. Huang, C. Y. Chen, L. Shen, R. R. Wang, and Z. W. Chen. 2009. In situ visualization of IL-22 cytokine response in tuberculosis, reply to Vani et al. J. Infect. Dis. 200: 482-484.
23. Yao, S., G. Zeng, D. Huang, C. Y. Chen, L. Halliday, R. R. Wang, and Z. W. Chen. 2010. Differentiation, distribution, and immune regulation of IL-22-producing Th17 cells during M. tuberculosis infection of macaques. PLoS Pathog. 6: e1000789.
24. Bruns, H., C. Meinken, P. Schauenberg, G. Härter, P. Kern, R. L. Modlin, C. Antoni, and S. Stenger. 2009. Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans. J. Clin. Invest. 119: 1167-1177.
25. Ostroukhova, M., Z. Qi, T. B. Oriss, B. Dixon-McCarthy, P. Ray, and A. Ray. 2006. Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta. J. Clin. Invest. 116: 996-1004.
26. Chen, C. Y., D. Huang, R. C. Wang, L. Shen, G. Zeng, S. Yao, Y. Shen, L. Halliday, J. Fortman, M. McAllister, et al. 2009. A critical role for CD8 T cells in a nonhuman primate model of tuberculosis. PLoS Pathog. 5: e1000392.
27. Shen, Y., D. Zhou, L. Qiu, X. Lai, M. Simon, L. Shen, Z. Kou, Q. Wang, L. Jiang, J. Estep, et al. 2002. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science 295: 2255-2258. (Pubitemid 34258837)
28. Wei, H., D. Huang, X. Lai, M. Chen, W. Zhong, R. Wang, and Z. W. Chen. 2008. Definition of APC presentation of phosphoantigen (E)-4-hydroxy-3-methyl- but- 2-enyl pyrophosphate to Vgamma2Vdelta 2 TCR. J. Immunol. 181: 4798-4806.
29. Wei, H., R. Wang, Z. Yuan, C. Y. Chen, D. Huang, L. Halliday, W. Zhong, G. Zeng, Y. Shen, L. Shen, et al. 2009. DR*W201/P65 tetramer visualization of epitope-specific CD4 T-cell during M. tuberculosis infection and its resting memory pool after BCG vaccination. PLoS One 4: e6905.
30. Zeng, G., J. Chen, L. Zhong, R. Wang, L. Jiang, J. Cai, L. Yan, D. Huang, C. Y. Chen, and Z. W. Chen. 2009. NSOM- and AFM-based nanotechnology elucidates nano-structural and atomic-force features of a Y. pestis V immunogen-containing particle vaccine capable of eliciting robust response. Proteomics 9: 1538-1547.
31. Chen, Y., J. Qin, and Z. W. Chen. 2008. Fluorescence-topographic NSOM directly visualizes peak-valley polarities of GM1/GM3 rafts in cell membrane fluctuations. J. Lipid Res. 49: 2268-2275.
32. Chen, Y., L. Shao, Z. Ali, J. Cai, and Z. W. Chen. 2008. NSOM/QD-based nanoscale immunofluorescence imaging of antigen-specific T-cell receptor responses during an in vivo clonal Vgamma2Vdelta2 T-cell expansion. Blood 111: 4220-4232.
33. Yong Chen, J. Q., J. Cai, and Z. W. Chen. 2009. Cold induces micro/nano-scale reorganization of lipid raft markers at mounds of cell-membrane fluctuations. PLoS One 4: e5386.
34. Huang, D., Y. Shen, L. Qiu, C. Y. Chen, L. Shen, J. Estep, R. Hunt, D. Vasconcelos, G. Du, P. Aye, et al. 2008. Immune distribution and localization of phosphoantigen-specific Vgamma2Vdelta2 T cells in lymphoid and nonlymphoid tissues in Mycobacterium tuberculosis infection. Infect. Immun. 76: 426-436.
35. Gong, G., L. Shao, Y. Wang, C. Y. Chen, D. Huang, S. Yao, X. Zhan, H. Sicard, R. Wang, and Z. W. Chen. 2009. Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection. Blood 113: 837-845.
36. Dumoutier, L., D. Lejeune, D. Colau, and J. C. Renauld. 2001. Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22. J. Immunol. 166: 7090-7095.
37. Yao, S., D. Huang, C. Y. Chen, L. Halliday, G. Zeng, R. C. Wang, and Z. W. Chen. 2010. Differentiation, distribution and gammadelta T cell-driven regulation of IL-22-producing T cells in tuberculosis. PLoS Pathog. 6: e1000789.
38. Fooksman, D. R., S. Vardhana, G. Vasiliver-Shamis, J. Liese, D. Blair, J. Waite, C. Sacristan, G. Victora, A. Zanin-Zhorov, and M. L. Dustin. 2009. Functional anatomy of T cell activation and synapse formation. Annu. Rev. Immunol. 182: 5179-5182.
39. Zhong, L., G. Zeng, X. Lu, R. C. Wang, G. Gong, L. Yan, D. Huang, and Z. W. Chen. 2009. NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nano-domains in T cell activation. PLoS One 4: e5945.
40. Dumoutier, L., J. Louahed, and J. C. Renauld. 2000. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J. Immunol. 164: 1814-1819.
41. Dhiman, R., M. Indramohan, P. F. Barnes, R. C. Nayak, P. Paidipally, L. V. Rao, and R. Vankayalapati. 2009. IL-22 produced by human NK cells inhibits growth of Mycobacterium tuberculosis by enhancing phagolysosomal fusion. J. Immunol. 183: 6639-6645.
42. Canaday, D. H., R. J. Wilkinson, Q. Li, C. V. Harding, R. F. Silver, and W. H. Boom. 2001. CD4(+) and CD8(+) T cells kill intracellular Mycobacterium tuberculosis by a perforin and Fas/Fas ligand-independent mechanism. J. Immunol. 167: 2734-2742.