Cx3cr1 deficiency in mice attenuates hepatic granuloma formation during acute schistosomiasis by enhancing the M2-type polarization of macrophages

DMM Disease Models and Mechanisms

Volumn 8, Issue 7, 2015, Pages 691-700

  Ran, Lin ^a,b   Yu, Qilin ^b   Zhang, Shu ^b   Xiong, Fei ^b   Cheng, Jia ^b   Yang, Ping ^b   Xu, Jun Fa ^c   Nie, Hao ^a   Zhong, Qin ^a   Yang, Xueli ^a   Yang, Fei ^a   Gong, Quan ^a   Kuczma, Michal ^d   Kraj, Piotr ^d   Gu, Weikuan ^e   Ren, Bo Xu ^a   Wang, Cong Yi ^a,b,c  

^a YANGTZE UNIVERSITY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c GUANGDONG MEDICAL UNIVERSITY   (China)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

^e UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

CX3CR1; Granuloma formation; Macrophage; Ppar ; Schistosomiasis; STAT 6

Indexed keywords

ALANINE AMINOTRANSFERASE; ARGINASE 1; ASPARTATE AMINOTRANSFERASE; CHEMOKINE RECEPTOR CX3CR1; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STAT6 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CHEMOKINE RECEPTOR CXCR1; STAT6 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; GRANULOMA; HEPATOMEGALY; IMMUNITY; LIVER FUNCTION; LIVER GRANULOMA; LIVER INJURY; LIVER WEIGHT; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCHISTOSOMIASIS JAPONICA; SIGNAL TRANSDUCTION; WEIGHT REDUCTION; ACUTE DISEASE; ANIMAL; C57BL MOUSE; CLASSIFICATION; COMPLICATION; DEFICIENCY; DISEASE MODEL; FEMALE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LIVER CIRRHOSIS, EXPERIMENTAL; LIVER DISEASES, PARASITIC; MACROPHAGE; METABOLISM; OVUM; PATHOLOGY; SCHISTOSOMA JAPONICUM; TH2 CELL;

MUS; SCHISTOSOMA JAPONICUM;

ACUTE DISEASE; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GRANULOMA; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; LIVER CIRRHOSIS, EXPERIMENTAL; LIVER DISEASES, PARASITIC; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OVUM; PPAR GAMMA; RECEPTORS, INTERLEUKIN-8A; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; TH2 CELLS;

EID: 84937930301     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.018242     Document Type: Article

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