IFN-γ-driven IDO production from macrophages protects IL-4Rα-deficient mice against lethality during schistosoma mansoni infection

American Journal of Pathology

Volumn 180, Issue 5, 2012, Pages 2001-2008

  Rani, Reena ^a   Jordan, Michael B ^b   Divanovic, Senad ^a   Herbert, De'Broski R ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; INTERLEUKIN 5; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL COUNT; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNOPATHOLOGY; LIVER GRANULOMA; LIVER INJURY; MACROPHAGE; MORTALITY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SCHISTOSOMIASIS MANSONI; SIGNAL TRANSDUCTION; TH1 CELL; TH17 CELL; TUMOR VOLUME; UPREGULATION; WEIGHT REDUCTION;

ACUTE DISEASE; ANIMALS; CYTOKINES; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERFERON-GAMMA; INTERLEUKIN-13; INTERLEUKIN-4; LIVER; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, TRANSGENIC; RECEPTORS, INTERLEUKIN-4; SCHISTOSOMIASIS MANSONI; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; WEIGHT LOSS;

EID: 84860247174     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.01.013     Document Type: Article

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