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Volumn 128, Issue 14, 2015, Pages 2454-2467

Sphingolipids regulate telomere clustering by affecting the transcription of genes involved in telomere homeostasis

Author keywords

Clustering; Glycosylphosphatidylinositol; Sphingolipid; Telomere; Yeast

Indexed keywords

SPHINGOLIPID; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSCRIPTION FACTOR;

EID: 84937914403     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.164160     Document Type: Article
Times cited : (10)

References (88)
  • 1
    • 54949084810 scopus 로고    scopus 로고
    • A genomewide suppressorand enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae.
    • Addinall, S. G.,Downey, M., Yu, M., Zubko,M.K., Dewar, J., Leake, A., Hallinan, J., Shaw, O., James,K.,Wilkinson, D. J. et al. (2008). A genomewide suppressorand enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae. Genetics 180, 2251-2266.
    • (2008) Genetics , vol.180 , pp. 2251-2266
    • Addinall, S.G.1    Downey, M.2    Yu, M.3    Zubko, M.K.4    Dewar, J.5    Leake, A.6    Hallinan, J.7    Shaw, O.8    James, K.9    Wilkinson, D.J.10
  • 2
    • 79955574694 scopus 로고    scopus 로고
    • Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.
    • Addinall, S. G., Holstein, E.-M., Lawless, C., Yu, M., Chapman, K., Banks, A. P., Ngo, H.-P., Maringele, L., Taschuk, M., Young, A. et al. (2011). Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects. PLoS Genet. 7, e1001362.
    • (2011) PLoS Genet. , vol.7 , pp. e1001362
    • Addinall, S.G.1    Holstein, E.-M.2    Lawless, C.3    Yu, M.4    Chapman, K.5    Banks, A.P.6    Ngo, H.-P.7    Maringele, L.8    Taschuk, M.9    Young, A.10
  • 3
    • 84897954101 scopus 로고    scopus 로고
    • Sphingolipid homeostasis in the web of metabolic routes.
    • Aguilera-Romero, A., Gehin, C. and Riezman, H. (2014). Sphingolipid homeostasis in the web of metabolic routes. Biochim. Biophys. Acta 1841, 647-656.
    • (2014) Biochim. Biophys. Acta , vol.1841 , pp. 647-656
    • Aguilera-Romero, A.1    Gehin, C.2    Riezman, H.3
  • 4
    • 0037453052 scopus 로고    scopus 로고
    • A Saccharomyces cerevisiae mutant strain defective in acetyl-CoA carboxylase arrests at the G2/M phase of the cell cycle.
    • Al-Feel, W., DeMar, J. C. and Wakil, S. J. (2003). A Saccharomyces cerevisiae mutant strain defective in acetyl-CoA carboxylase arrests at the G2/M phase of the cell cycle. Proc. Natl. Acad. Sci. USA 100, 3095-3100.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 3095-3100
    • Al-Feel, W.1    DeMar, J.C.2    Wakil, S.J.3
  • 5
    • 33846605450 scopus 로고    scopus 로고
    • The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering.
    • Antoniacci, L. M., Kenna, M. A. and Skibbens, R. V. (2007). The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering. Cell Cycle 6, 75-79.
    • (2007) Cell Cycle , vol.6 , pp. 75-79
    • Antoniacci, L.M.1    Kenna, M.A.2    Skibbens, R.V.3
  • 8
    • 0032515061 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant.
    • Beeler, T., Bacikova,D.,Gable, K., Hopkins, L., Johnson, C., Slife, H. and Dunn, T. (1998). The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant. J. Biol. Chem. 273, 30688-30694.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30688-30694
    • Beeler, T.1    Bacikova, D.2    Gable, K.3    Hopkins, L.4    Johnson, C.5    Slife, H.6    Dunn, T.7
  • 9
    • 84860501617 scopus 로고    scopus 로고
    • Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.
    • Berchtold, D., Piccolis, M., Chiaruttini, N., Riezman, I., Riezman, H., Roux, A., Walther, T. C. and Loewith, R. (2012). Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis. Nat. Cell Biol. 14, 542-547.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 542-547
    • Berchtold, D.1    Piccolis, M.2    Chiaruttini, N.3    Riezman, I.4    Riezman, H.5    Roux, A.6    Walther, T.C.7    Loewith, R.8
  • 10
    • 33847784791 scopus 로고    scopus 로고
    • Multiple levels of cyclin specificity in cell-cycle control.
    • Bloom, J. and Cross, F. R. (2007). Multiple levels of cyclin specificity in cell-cycle control. Nat. Rev. Mol. Cell Biol. 8, 149-160.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 149-160
    • Bloom, J.1    Cross, F.R.2
  • 11
    • 78649373124 scopus 로고    scopus 로고
    • Membranes in balance: mechanisms of sphingolipid homeostasis.
    • Breslow, D. K. and Weissman, J. S. (2010). Membranes in balance: mechanisms of sphingolipid homeostasis. Mol. Cell 40, 267-279.
    • (2010) Mol. Cell , vol.40 , pp. 267-279
    • Breslow, D.K.1    Weissman, J.S.2
  • 13
    • 33645962805 scopus 로고    scopus 로고
    • Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes.
    • Chikashige, Y., Tsutsumi, C., Yamane, M., Okamasa, K., Haraguchi, T. and Hiraoka, Y. (2006). Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes. Cell 125, 59-69.
    • (2006) Cell , vol.125 , pp. 59-69
    • Chikashige, Y.1    Tsutsumi, C.2    Yamane, M.3    Okamasa, K.4    Haraguchi, T.5    Hiraoka, Y.6
  • 14
    • 48449099276 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae SFP1: at the crossroads of central metabolism and ribosome biogenesis.
    • Cipollina, C., van den Brink, J., Daran-Lapujade, P., Pronk, J. T., Porro, D. and de Winde, J. H. (2008). Saccharomyces cerevisiae SFP1: at the crossroads of central metabolism and ribosome biogenesis. Microbiology 154, 1686-1699.
    • (2008) Microbiology , vol.154 , pp. 1686-1699
    • Cipollina, C.1    van den Brink, J.2    Daran-Lapujade, P.3    Pronk, J.T.4    Porro, D.5    de Winde, J.H.6
  • 15
    • 84871687005 scopus 로고    scopus 로고
    • Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly.
    • Crabbe, L., Cesare, A. J., Kasuboski, J. M., Fitzpatrick, J. A. J. and Karlseder, J. (2012). Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly. Cell Rep. 2, 1521-1529.
    • (2012) Cell Rep. , vol.2 , pp. 1521-1529
    • Crabbe, L.1    Cesare, A.J.2    Kasuboski, J.M.3    Fitzpatrick, J.A.J.4    Karlseder, J.5
  • 16
    • 0344423818 scopus 로고    scopus 로고
    • Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae.
    • Craven, R. J. and Petes, T. D. (1999). Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae. Genetics 152, 1531-1541.
    • (1999) Genetics , vol.152 , pp. 1531-1541
    • Craven, R.J.1    Petes, T.D.2
  • 18
    • 78649705898 scopus 로고    scopus 로고
    • Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.
    • Dewar, J. M. and Lydall, D. (2010). Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. EMBO J. 29, 4020-4034.
    • (2010) EMBO J. , vol.29 , pp. 4020-4034
    • Dewar, J.M.1    Lydall, D.2
  • 19
    • 50049119791 scopus 로고    scopus 로고
    • Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast.
    • Dickson, R. C. (2008). Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast. J. Lipid Res. 49, 909-921.
    • (2008) J. Lipid Res. , vol.49 , pp. 909-921
    • Dickson, R.C.1
  • 20
    • 80051720034 scopus 로고    scopus 로고
    • Distinct interactions select and maintain a specific cell fate.
    • Doncic, A., Falleur-Fettig, M. and Skotheim, J. M. (2011). Distinct interactions select and maintain a specific cell fate. Mol. Cell 43, 528-539.
    • (2011) Mol. Cell , vol.43 , pp. 528-539
    • Doncic, A.1    Falleur-Fettig, M.2    Skotheim, J.M.3
  • 22
    • 0031028654 scopus 로고    scopus 로고
    • Fungicidal action of aureobasidin A, a cyclic depsipeptide antifungal antibiotic, against Saccharomyces cerevisiae.
    • Endo, M., Takesako, K., Kato, I. and Yamaguchi, H. (1997). Fungicidal action of aureobasidin A, a cyclic depsipeptide antifungal antibiotic, against Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 41, 672-676.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 672-676
    • Endo, M.1    Takesako, K.2    Kato, I.3    Yamaguchi, H.4
  • 23
    • 84890837804 scopus 로고    scopus 로고
    • The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery.
    • Ferreira, H. C., Towbin, B. D., Jegou, T. and Gasser, S. M. (2013). The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery. J. Cell Biol. 203, 727-735.
    • (2013) J. Cell Biol. , vol.203 , pp. 727-735
    • Ferreira, H.C.1    Towbin, B.D.2    Jegou, T.3    Gasser, S.M.4
  • 25
    • 0035842889 scopus 로고    scopus 로고
    • Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast.
    • Funato, K. and Riezman, H. (2001). Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast. J. Cell Biol. 155, 949-960.
    • (2001) J. Cell Biol. , vol.155 , pp. 949-960
    • Funato, K.1    Riezman, H.2
  • 26
    • 0037168471 scopus 로고    scopus 로고
    • Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae.
    • Funato, K., Vallée, B. and Riezman, H. (2002). Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae. Biochemistry 41, 15105-15114.
    • (2002) Biochemistry , vol.41 , pp. 15105-15114
    • Funato, K.1    Vallée, B.2    Riezman, H.3
  • 27
    • 80855144827 scopus 로고    scopus 로고
    • Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1.
    • Garcia, V., Phelps, S. E. L., Gray, S. and Neale, M. J. (2011). Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1. Nature 479, 241-244.
    • (2011) Nature , vol.479 , pp. 241-244
    • Garcia, V.1    Phelps, S.E.L.2    Gray, S.3    Neale, M.J.4
  • 28
    • 78049518892 scopus 로고    scopus 로고
    • An overview of sphingolipid metabolism: from synthesis to breakdown.
    • Gault, C. R., Obeid, L. M. and Hannun, Y. A. (2010). An overview of sphingolipid metabolism: from synthesis to breakdown. Adv. Exp. Med. Biol. 688, 1-23.
    • (2010) Adv. Exp. Med. Biol. , vol.688 , pp. 1-23
    • Gault, C.R.1    Obeid, L.M.2    Hannun, Y.A.3
  • 29
    • 0029820640 scopus 로고    scopus 로고
    • The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae.
    • Gotta, M., Laroche, T., Formenton, A., Maillet, L., Scherthan, H. and Gasser, S. M. (1996). The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae. J. Cell Biol. 134, 1349-1363.
    • (1996) J. Cell Biol. , vol.134 , pp. 1349-1363
    • Gotta, M.1    Laroche, T.2    Formenton, A.3    Maillet, L.4    Scherthan, H.5    Gasser, S.M.6
  • 31
    • 0030701535 scopus 로고    scopus 로고
    • Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p.
    • Haak, D., Gable, K., Beeler, T. and Dunn, T. (1997). Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p. J. Biol. Chem. 272, 29704-29710.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29704-29710
    • Haak, D.1    Gable, K.2    Beeler, T.3    Dunn, T.4
  • 32
    • 0033592983 scopus 로고    scopus 로고
    • Rapamycin-modulated transcription defines the subset of nutrientsensitive signaling pathways directly controlled by the Tor proteins.
    • Hardwick, J. S., Kuruvilla, F. G., Tong, J. K., Shamji, A. F. and Schreiber, S. L. (1999). Rapamycin-modulated transcription defines the subset of nutrientsensitive signaling pathways directly controlled by the Tor proteins. Proc. Natl. Acad. Sci. USA 96, 14866-14870.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14866-14870
    • Hardwick, J.S.1    Kuruvilla, F.G.2    Tong, J.K.3    Shamji, A.F.4    Schreiber, S.L.5
  • 33
    • 0347416978 scopus 로고    scopus 로고
    • Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5′ to 3′ mRNA decay pathways in yeast.
    • He, F., Li, X., Spatrick, P., Casillo, R., Dong, S. and Jacobson, A. (2003). Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5′ to 3′ mRNA decay pathways in yeast. Mol. Cell 12, 1439-1452.
    • (2003) Mol. Cell , vol.12 , pp. 1439-1452
    • He, F.1    Li, X.2    Spatrick, P.3    Casillo, R.4    Dong, S.5    Jacobson, A.6
  • 34
    • 84867096429 scopus 로고    scopus 로고
    • Sphingolipid signaling in metabolic disorders.
    • Hla, T. and Dannenberg, A. J. (2012). Sphingolipid signaling in metabolic disorders. Cell Metab. 16, 420-434.
    • (2012) Cell Metab. , vol.16 , pp. 420-434
    • Hla, T.1    Dannenberg, A.J.2
  • 35
    • 80052767367 scopus 로고    scopus 로고
    • Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres.
    • Horigome, C., Okada, T., Shimazu, K., Gasser, S. M. and Mizuta, K. (2011). Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres. EMBO J. 30, 3799-3811.
    • (2011) EMBO J. , vol.30 , pp. 3799-3811
    • Horigome, C.1    Okada, T.2    Shimazu, K.3    Gasser, S.M.4    Mizuta, K.5
  • 36
    • 84878681624 scopus 로고    scopus 로고
    • Spatial telomere organization and clustering in yeast Saccharomyces cerevisiae nucleus is generated by a randomdynamics of aggregation-dissociation.
    • s1-s10
    • Hoze, N., Ruault, M., Amoruso, C., Taddei, A. and Holcman, D. (2013). Spatial telomere organization and clustering in yeast Saccharomyces cerevisiae nucleus is generated by a randomdynamics of aggregation-dissociation. Mol. Biol. Cell 24, 1791-1800, s1-10.
    • (2013) Mol. Biol. Cell , vol.24 , pp. 1791-1800
    • Hoze, N.1    Ruault, M.2    Amoruso, C.3    Taddei, A.4    Holcman, D.5
  • 38
    • 0037341611 scopus 로고    scopus 로고
    • Short telomeres induce a DNA damage response in Saccharomyces cerevisiae.
    • IJpma, A. S. and Greider, C. W. (2003). Short telomeres induce a DNA damage response in Saccharomyces cerevisiae. Mol. Biol. Cell 14, 987-1001.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 987-1001
    • Ijpma, A.S.1    Greider, C.W.2
  • 39
    • 33748119341 scopus 로고    scopus 로고
    • The Sad1-UNC-84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope.
    • Jaspersen, S. L., Martin, A. E., Glazko, G., Giddings, T. H., Jr, Morgan, G., Mushegian, A. and Winey, M. (2006). The Sad1-UNC-84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope. J. Cell Biol. 174, 665-675.
    • (2006) J. Cell Biol. , vol.174 , pp. 665-675
    • Jaspersen, S.L.1    Martin, A.E.2    Glazko, G.3    Giddings, T.H.4    Morgan, G.5    Mushegian, A.6    Winey, M.7
  • 40
    • 0035896640 scopus 로고    scopus 로고
    • Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.
    • Jenkins, G. M. and Hannun, Y. A. (2001). Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae. J. Biol. Chem. 276, 8574-8581.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8574-8581
    • Jenkins, G.M.1    Hannun, Y.A.2
  • 41
    • 47149083740 scopus 로고    scopus 로고
    • Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.
    • Kajiwara, K.,Watanabe, R., Pichler, H., Ihara, K., Murakami, S., Riezman, H. and Funato, K. (2008). Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum. Mol. Biol. Cell 19, 2069-2082.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2069-2082
    • Kajiwara, K.1    Watanabe, R.2    Pichler, H.3    Ihara, K.4    Murakami, S.5    Riezman, H.6    Funato, K.7
  • 42
    • 84870243020 scopus 로고    scopus 로고
    • Perturbation of sphingolipid metabolism induces endoplasmic reticulum stress-mediated mitochondrial apoptosis in budding yeast.
    • Kajiwara, K., Muneoka, T., Watanabe, Y., Karashima, T., Kitagaki, H. and Funato, K. (2012). Perturbation of sphingolipid metabolism induces endoplasmic reticulum stress-mediated mitochondrial apoptosis in budding yeast. Mol. Microbiol. 86, 1246-1261.
    • (2012) Mol. Microbiol. , vol.86 , pp. 1246-1261
    • Kajiwara, K.1    Muneoka, T.2    Watanabe, Y.3    Karashima, T.4    Kitagaki, H.5    Funato, K.6
  • 45
    • 84881238330 scopus 로고    scopus 로고
    • SIR proteins and the assembly of silent chromatin in budding yeast.
    • Kueng, S., Oppikofer, M. and Gasser, S. M. (2013). SIR proteins and the assembly of silent chromatin in budding yeast. Annu. Rev. Genet. 47, 275-306.
    • (2013) Annu. Rev. Genet. , vol.47 , pp. 275-306
    • Kueng, S.1    Oppikofer, M.2    Gasser, S.M.3
  • 47
    • 0030455861 scopus 로고    scopus 로고
    • Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.
    • Lendvay, T. S., Morris, D. K., Sah, J., Balasubramanian, B. and Lundblad, V. (1996). Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics 144, 1399-1412.
    • (1996) Genetics , vol.144 , pp. 1399-1412
    • Lendvay, T.S.1    Morris, D.K.2    Sah, J.3    Balasubramanian, B.4    Lundblad, V.5
  • 48
    • 83455177213 scopus 로고    scopus 로고
    • Target of rapamycin (TOR) in nutrient signaling and growth control.
    • Loewith, R. and Hall, M. N. (2011). Target of rapamycin (TOR) in nutrient signaling and growth control. Genetics 189, 1177-1201.
    • (2011) Genetics , vol.189 , pp. 1177-1201
    • Loewith, R.1    Hall, M.N.2
  • 49
    • 38349073475 scopus 로고    scopus 로고
    • DNA damage response at functional and dysfunctional telomeres.
    • Longhese, M. P. (2008). DNA damage response at functional and dysfunctional telomeres. Genes Dev. 22, 125-140.
    • (2008) Genes Dev. , vol.22 , pp. 125-140
    • Longhese, M.P.1
  • 50
    • 38049082181 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.
    • Luke, B., Azzalin, C. M., Hug, N., Deplazes, A., Peter, M. and Lingner, J. (2007). Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay. Nucleic Acids Res. 35, 7688-7697.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7688-7697
    • Luke, B.1    Azzalin, C.M.2    Hug, N.3    Deplazes, A.4    Peter, M.5    Lingner, J.6
  • 52
  • 53
    • 0036682516 scopus 로고    scopus 로고
    • EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants.
    • Maringele, L. and Lydall, D. (2002). EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev. 16, 1919-1933.
    • (2002) Genes Dev. , vol.16 , pp. 1919-1933
    • Maringele, L.1    Lydall, D.2
  • 54
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo.
    • Melo, J. A., Cohen, J. and Toczyski, D. P. (2001). Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev. 15, 2809-2821.
    • (2001) Genes Dev. , vol.15 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 56
    • 0035692142 scopus 로고    scopus 로고
    • Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism.
    • Moreau, S., Morgan, E. A. and Symington, L. S. (2001). Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism. Genetics 159, 1423-1433.
    • (2001) Genetics , vol.159 , pp. 1423-1433
    • Moreau, S.1    Morgan, E.A.2    Symington, L.S.3
  • 58
    • 0037984352 scopus 로고    scopus 로고
    • Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiae.
    • Pang, T.- L., Wang, C.-Y., Hsu, C.-L., Chen, M.-Y. and Lin, J.-J. (2003). Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiae. J. Biol. Chem. 278, 9318-9321.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9318-9321
    • Pang, T.-L.1    Wang, C.-Y.2    Hsu, C.-L.3    Chen, M.-Y.4    Lin, J.-J.5
  • 59
    • 78650682926 scopus 로고    scopus 로고
    • Sphingolipids and expression regulation of genes in cancer.
    • Patwardhan, G. A. and Liu, Y.-Y. (2011). Sphingolipids and expression regulation of genes in cancer. Prog. Lipid. Res. 50, 104-114.
    • (2011) Prog. Lipid. Res. , vol.50 , pp. 104-114
    • Patwardhan, G.A.1    Liu, Y.-Y.2
  • 60
    • 55549130803 scopus 로고    scopus 로고
    • Regulation of telomere length by fatty acid elongase 3 in yeast: involvement of inositol phosphate metabolism and Ku70/80 function.
    • Ponnusamy, S., Alderson, N. L., Hama, H., Bielawski, J., Jiang, J. C., Bhandari, R., Snyder, S. H., Jazwinski, S. M. and Ogretmen, B. (2008). Regulation of telomere length by fatty acid elongase 3 in yeast: involvement of inositol phosphate metabolism and Ku70/80 function. J. Biol. Chem. 283, 27514-27524.
    • (2008) J. Biol. Chem. , vol.283 , pp. 27514-27524
    • Ponnusamy, S.1    Alderson, N.L.2    Hama, H.3    Bielawski, J.4    Jiang, J.C.5    Bhandari, R.6    Snyder, S.H.7    Jazwinski, S.M.8    Ogretmen, B.9
  • 61
    • 51049092483 scopus 로고    scopus 로고
    • Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition.
    • Puglisi, A., Bianchi, A., Lemmens, L., Damay, P. and Shore, D. (2008). Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition. EMBO J. 27, 2328-2339.
    • (2008) EMBO J. , vol.27 , pp. 2328-2339
    • Puglisi, A.1    Bianchi, A.2    Lemmens, L.3    Damay, P.4    Shore, D.5
  • 62
    • 0038012805 scopus 로고    scopus 로고
    • Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast.
    • Qi, H., Li, T.-K., Kuo, D., Nur-E-Kamal, A. and Liu, L. F. (2003). Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast. J. Biol. Chem. 278, 15136-15141.
    • (2003) J. Biol. Chem. , vol.278 , pp. 15136-15141
    • Qi, H.1    Li, T.-K.2    Kuo, D.3    Nur-E-Kamal, A.4    Liu, L.F.5
  • 63
    • 55849125436 scopus 로고    scopus 로고
    • TOR regulates cell death induced by telomere dysfunction in budding yeast.
    • Qi, H., Chen, Y., Fu, X., Lin, C.-P., Zheng, X. F. S. and Liu, L. F. (2008). TOR regulates cell death induced by telomere dysfunction in budding yeast. PLoS ONE 3, e3520.
    • (2008) PLoS ONE , vol.3 , pp. e3520
    • Qi, H.1    Chen, Y.2    Fu, X.3    Lin, C.-P.4    Zheng, X.F.S.5    Liu, L.F.6
  • 64
    • 79551696674 scopus 로고    scopus 로고
    • Clustering heterochromatin: Sir3 promotes telomere clustering independently of silencing in yeast.
    • Ruault, M., De Meyer, A., Loiodice, I. and Taddei, A. (2011). Clustering heterochromatin: Sir3 promotes telomere clustering independently of silencing in yeast. J. Cell Biol. 192, 417-431.
    • (2011) J. Cell Biol. , vol.192 , pp. 417-431
    • Ruault, M.1    De Meyer, A.2    Loiodice, I.3    Taddei, A.4
  • 65
    • 77952119807 scopus 로고    scopus 로고
    • The Rpd3L HDAC complex is essential for the heat stress response in yeast.
    • Ruiz-Roig, C., Vieitez, C., Posas, F. and De Nadal, E. (2010). The Rpd3L HDAC complex is essential for the heat stress response in yeast. Mol. Microbiol. 76, 1049-1062.
    • (2010) Mol. Microbiol. , vol.76 , pp. 1049-1062
    • Ruiz-Roig, C.1    Vieitez, C.2    Posas, F.3    De Nadal, E.4
  • 66
    • 13644269281 scopus 로고    scopus 로고
    • Multiple lipid transport pathways to the plasma membrane in yeast.
    • Schnabl, M., Daum, G. and Pichler, H. (2005). Multiple lipid transport pathways to the plasma membrane in yeast. Biochim. Biophys. Acta 1687, 130-140.
    • (2005) Biochim. Biophys. Acta , vol.1687 , pp. 130-140
    • Schnabl, M.1    Daum, G.2    Pichler, H.3
  • 67
    • 65249165924 scopus 로고    scopus 로고
    • Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination.
    • Schober, H., Ferreira, H., Kalck, V., Gehlen, L. R. and Gasser, S. M. (2009). Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes Dev. 23, 928-938.
    • (2009) Genes Dev. , vol.23 , pp. 928-938
    • Schober, H.1    Ferreira, H.2    Kalck, V.3    Gehlen, L.R.4    Gasser, S.M.5
  • 69
    • 84875170467 scopus 로고    scopus 로고
    • TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis.
    • Shimobayashi, M., Oppliger, W., Moes, S., Jeno, P. and Hall, M. N. (2013). TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis. Mol. Biol. Cell 24, 870-881.
    • (2013) Mol. Biol. Cell , vol.24 , pp. 870-881
    • Shimobayashi, M.1    Oppliger, W.2    Moes, S.3    Jeno, P.4    Hall, M.N.5
  • 73
    • 0035065881 scopus 로고    scopus 로고
    • Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant.
    • Teo, S.-H. and Jackson, S. P. (2001). Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant. EMBO Rep. 2, 197-202.
    • (2001) EMBO Rep. , vol.2 , pp. 197-202
    • Teo, S.-H.1    Jackson, S.P.2
  • 74
    • 31044432248 scopus 로고    scopus 로고
    • Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region.
    • Therizols, P., Fairhead, C., Cabal, G. G., Genovesio, A., Olivo-Marin, J.-C., Dujon, B. and Fabre, E. (2006). Telomere tethering at the nuclear periphery is essential for efficient DNA double strand break repair in subtelomeric region. J. Cell Biol. 172, 189-199.
    • (2006) J. Cell Biol. , vol.172 , pp. 189-199
    • Therizols, P.1    Fairhead, C.2    Cabal, G.G.3    Genovesio, A.4    Olivo-Marin, J.-C.5    Dujon, B.6    Fabre, E.7
  • 75
    • 0034731399 scopus 로고    scopus 로고
    • Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1.
    • Tinkelenberg, A. H., Liu, Y., Alcantara, F., Khan, S., Guo, Z., Bard, M. and Sturley, S. L. (2000). Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1. J. Biol. Chem. 275, 40667-40670.
    • (2000) J. Biol. Chem. , vol.275 , pp. 40667-40670
    • Tinkelenberg, A.H.1    Liu, Y.2    Alcantara, F.3    Khan, S.4    Guo, Z.5    Bard, M.6    Sturley, S.L.7
  • 76
    • 84155163063 scopus 로고    scopus 로고
    • Tor complex 1 controls telomere length by affecting the level of Ku.
    • Ungar, L., Harari, Y., Toren, A. and Kupiec, M. (2011). Tor complex 1 controls telomere length by affecting the level of Ku. Curr. Biol. 21, 2115-2120.
    • (2011) Curr. Biol. , vol.21 , pp. 2115-2120
    • Ungar, L.1    Harari, Y.2    Toren, A.3    Kupiec, M.4
  • 78
    • 79951525332 scopus 로고    scopus 로고
    • The putative lipid transporter, Arv1, is required for activating pheromone-induced MAP kinase signaling in Saccharomyces cerevisiae.
    • Villasmil, M. L., Ansbach, A. and Nickels, J. T., Jr (2011). The putative lipid transporter, Arv1, is required for activating pheromone-induced MAP kinase signaling in Saccharomyces cerevisiae. Genetics 187, 455-465.
    • (2011) Genetics , vol.187 , pp. 455-465
    • Villasmil, M.L.1    Ansbach, A.2    Nickels, J.T.3
  • 79
    • 84865105439 scopus 로고    scopus 로고
    • Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.
    • Wellinger, R. J. and Zakian, V. A. (2012). Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end. Genetics 191, 1073-1105.
    • (2012) Genetics , vol.191 , pp. 1073-1105
    • Wellinger, R.J.1    Zakian, V.A.2
  • 80
    • 84884952011 scopus 로고    scopus 로고
    • Clustering and protein dynamics of Drosophila melanogaster telomeres.
    • Wesolowska, N., Amariei, F. L. and Rong, Y. S. (2013). Clustering and protein dynamics of Drosophila melanogaster telomeres. Genetics 195, 381-391.
    • (2013) Genetics , vol.195 , pp. 381-391
    • Wesolowska, N.1    Amariei, F.L.2    Rong, Y.S.3
  • 81
    • 72449166463 scopus 로고    scopus 로고
    • TEN1 is essential for CDC13-mediated telomere capping.
    • Xu, L., Petreaca, R. C., Gasparyan, H. J., Vu, S. and Nugent, C. I. (2009). TEN1 is essential for CDC13-mediated telomere capping. Genetics 183, 793-810.
    • (2009) Genetics , vol.183 , pp. 793-810
    • Xu, L.1    Petreaca, R.C.2    Gasparyan, H.J.3    Vu, S.4    Nugent, C.I.5
  • 82
    • 0034659799 scopus 로고    scopus 로고
    • Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae.
    • Zanolari, B., Friant, S., Funato, K., Sü tterlin, C., Stevenson, B. J. and Riezman, H. (2000). Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae. EMBO J. 19, 2824-2833.
    • (2000) EMBO J. , vol.19 , pp. 2824-2833
    • Zanolari, B.1    Friant, S.2    Funato, K.3    Sütterlin, C.4    Stevenson, B.J.5    Riezman, H.6
  • 83
    • 16344370926 scopus 로고    scopus 로고
    • A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization.
    • Zhao, X. and Blobel, G. (2005). A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc. Natl. Acad. Sci. USA 102, 4777-4782.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 4777-4782
    • Zhao, X.1    Blobel, G.2
  • 84
    • 84879049031 scopus 로고    scopus 로고
    • The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress.
    • Zhao, Y., Macgurn, J. A., Liu, M. and Emr, S. (2013). The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress. Elife 2, e00459.
    • (2013) Elife , vol.2 , pp. e00459
    • Zhao, Y.1    Macgurn, J.A.2    Liu, M.3    Emr, S.4
  • 85
    • 0033994222 scopus 로고    scopus 로고
    • The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA.
    • Zhou, J., Hidaka, K. and Futcher, B. (2000). The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA. Mol. Cell. Biol. 20, 1947-1955.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1947-1955
    • Zhou, J.1    Hidaka, K.2    Futcher, B.3
  • 86
    • 2342483301 scopus 로고    scopus 로고
    • Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells.
    • Zhou, C., Gehrig, P. A., Whang, Y. E. and Boggess, J. F. (2003). Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells. Mol. Cancer Ther. 2, 789-795.
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 789-795
    • Zhou, C.1    Gehrig, P.A.2    Whang, Y.E.3    Boggess, J.F.4
  • 87
    • 67649882797 scopus 로고    scopus 로고
    • Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation.
    • Zhou, J., Zhou, B. O., Lenzmeier, B. A. and Zhou, J.-Q. (2009). Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation. Nucleic Acids Res. 37, 3699-3713.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 3699-3713
    • Zhou, J.1    Zhou, B.O.2    Lenzmeier, B.A.3    Zhou, J.-Q.4
  • 88
    • 5144219712 scopus 로고    scopus 로고
    • Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants
    • Zubko, M. K., Guillard, S. and Lydall, D. (2004). Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants. Genetics 168, 103-115.
    • (2004) Genetics , vol.168 , pp. 103-115
    • Zubko, M.K.1    Guillard, S.2    Lydall, D.3


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