-
1
-
-
84876812210
-
Mental health: On the spectrum
-
Adam D, (2013) Mental health: On the spectrum. Nature 496: 416-418.
-
(2013)
Nature
, vol.496
, pp. 416-418
-
-
Adam, D.1
-
2
-
-
84883538421
-
Converging evidence for the association of functional genetic variation in the serotonin receptor 2a gene with prefrontal function and olanzapine treatment
-
Blasi G, De Virgilio C, Papazacharias A,. (2013) Converging evidence for the association of functional genetic variation in the serotonin receptor 2a gene with prefrontal function and olanzapine treatment. JAMA Psychiatry 70: 921-930.
-
(2013)
JAMA Psychiatry
, vol.70
, pp. 921-930
-
-
Blasi, G.1
De Virgilio, C.2
Papazacharias, A.3
-
3
-
-
84925869807
-
The importance of endophenotypes in schizophrenia research
-
Braff DL, (2015) The importance of endophenotypes in schizophrenia research. Schizophr Res 163: 1-8.
-
(2015)
Schizophr Res
, vol.163
, pp. 1-8
-
-
Braff, D.L.1
-
4
-
-
33745684557
-
Gene-environment interactions in psychiatry: joining forces with neuroscience
-
Caspi A, Moffitt TE, (2006) Gene-environment interactions in psychiatry: joining forces with neuroscience. Nat Rev Neurosci 7: 583-590.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 583-590
-
-
Caspi, A.1
Moffitt, T.E.2
-
5
-
-
84923186910
-
Genotype to phenotype relationships in autism spectrum disorders
-
Chang J, Gilman SR, Chiang AH,. (2015) Genotype to phenotype relationships in autism spectrum disorders. Nature Neurosci 18: 191-198.
-
(2015)
Nature Neurosci
, vol.18
, pp. 191-198
-
-
Chang, J.1
Gilman, S.R.2
Chiang, A.H.3
-
6
-
-
84876296688
-
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
-
Consortium C-DGotPG (2013) Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 381: 1371-1379.
-
(2013)
Lancet
, vol.381
, pp. 1371-1379
-
-
-
7
-
-
84925434860
-
The genetic and epigenetic landscape for CNS drug discovery targeting cross-diagnostic behavioral domains
-
de Mooij-van Malsen A, Pjetri E, Kas MJ, (2015) The genetic and epigenetic landscape for CNS drug discovery targeting cross-diagnostic behavioral domains. Eur J Pharmacol 753: 135-139.
-
(2015)
Eur J Pharmacol
, vol.753
, pp. 135-139
-
-
De Mooij-Van Malsen, A.1
Pjetri, E.2
Kas, M.J.3
-
8
-
-
33645779095
-
Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism
-
Dick DM, Jones K, Saccone N,. (2006) Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism. Behav Genetics 36: 112-126.
-
(2006)
Behav Genetics
, vol.36
, pp. 112-126
-
-
Dick, D.M.1
Jones, K.2
Saccone, N.3
-
9
-
-
0023255401
-
Twin concordance for DSM-III schizophrenia. Scrutinizing the validity of the definition
-
Farmer AE, McGuffin P, Gottesman II, (1987) Twin concordance for DSM-III schizophrenia. Scrutinizing the validity of the definition. Arch Gen Psychiatry 44: 634-641.
-
(1987)
Arch Gen Psychiatry
, vol.44
, pp. 634-641
-
-
Farmer, A.E.1
McGuffin, P.2
Gottesman, I.I.3
-
10
-
-
84898659513
-
Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees
-
Fears SC, Service SK, Kremeyer B,. (2014) Multisystem component phenotypes of bipolar disorder for genetic investigations of extended pedigrees. JAMA Psychiatry 71: 375-387.
-
(2014)
JAMA Psychiatry
, vol.71
, pp. 375-387
-
-
Fears, S.C.1
Service, S.K.2
Kremeyer, B.3
-
11
-
-
84872862360
-
Candidate and non-candidate genes in behavior genetics
-
Flint J, Munafo MR, (2013) Candidate and non-candidate genes in behavior genetics. Curr Opin Neurobiol 23: 57-61.
-
(2013)
Curr Opin Neurobiol
, vol.23
, pp. 57-61
-
-
Flint, J.1
Munafo, M.R.2
-
12
-
-
84904821257
-
Schizophrenia: genesis of a complex disease
-
Flint J, Munafo M, (2014) Schizophrenia: genesis of a complex disease. Nature 511: 412-413.
-
(2014)
Nature
, vol.511
, pp. 412-413
-
-
Flint, J.1
Munafo, M.2
-
13
-
-
84919666255
-
Assessing the utility of intermediate phenotypes for genetic mapping of psychiatric disease
-
Flint J, Timpson N, Munafo M, (2014) Assessing the utility of intermediate phenotypes for genetic mapping of psychiatric disease. Trends Neurosci 37: 733-741.
-
(2014)
Trends Neurosci
, vol.37
, pp. 733-741
-
-
Flint, J.1
Timpson, N.2
Munafo, M.3
-
14
-
-
84922217833
-
An AUTS2-Polycomb complex activates gene expression in the CNS
-
Gao Z, Lee P, Stafford JM,. (2014) An AUTS2-Polycomb complex activates gene expression in the CNS. Nature 516: 349-354.
-
(2014)
Nature
, vol.516
, pp. 349-354
-
-
Gao, Z.1
Lee, P.2
Stafford, J.M.3
-
15
-
-
84905582433
-
Most genetic risk for autism resides with common variation
-
Gaugler T, Klei L, Sanders SJ,. (2014) Most genetic risk for autism resides with common variation. Nature Genetics 46: 881-885.
-
(2014)
Nature Genetics
, vol.46
, pp. 881-885
-
-
Gaugler, T.1
Klei, L.2
Sanders, S.J.3
-
16
-
-
82755192975
-
High dimensional endophenotype ranking in the search for major depression risk genes
-
Glahn DC, Curran JE, Winkler AM,. (2012) High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry 71: 6-14.
-
(2012)
Biol Psychiatry
, vol.71
, pp. 6-14
-
-
Glahn, D.C.1
Curran, J.E.2
Winkler, A.M.3
-
17
-
-
84893725555
-
Arguments for the sake of endophenotypes: examining common misconceptions about the use of endophenotypes in psychiatric genetics
-
Glahn DC, Knowles EE, McKay DR,. (2014) Arguments for the sake of endophenotypes: examining common misconceptions about the use of endophenotypes in psychiatric genetics. Am J Med Genetics B Neuropsychiatric genetics 165B: 122-130.
-
(2014)
Am J Med Genetics B Neuropsychiatric genetics
, vol.165
, pp. 122-130
-
-
Glahn, D.C.1
Knowles, E.E.2
McKay, D.R.3
-
18
-
-
33644753148
-
Psychiatric endophenotypes and the development of valid animal models
-
Gould TD, Gottesman II, (2006) Psychiatric endophenotypes and the development of valid animal models. Genes Brain Behav 5: 113-119.
-
(2006)
Genes Brain Behav
, vol.5
, pp. 113-119
-
-
Gould, T.D.1
Gottesman, I.I.2
-
19
-
-
75149154292
-
Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'
-
Hannan A, (2010) Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'. Trends Genet 26: 59-65.
-
(2010)
Trends Genet
, vol.26
, pp. 59-65
-
-
Hannan, A.1
-
20
-
-
84922215950
-
Recent genetic findings in schizophrenia and their therapeutic relevance
-
Harrison PJ, (2015) Recent genetic findings in schizophrenia and their therapeutic relevance. J Psychopharmacol 29: 85-96.
-
(2015)
J Psychopharmacol
, vol.29
, pp. 85-96
-
-
Harrison, P.J.1
-
21
-
-
79957441385
-
Discovering imaging endophenotypes for major depression
-
Hasler G, Northoff G, (2011) Discovering imaging endophenotypes for major depression. Mol Psychiatry 16: 604-619.
-
(2011)
Mol Psychiatry
, vol.16
, pp. 604-619
-
-
Hasler, G.1
Northoff, G.2
-
22
-
-
84922464660
-
Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: a translational approach
-
Heinzmann JM, Kloiber S, Ebling-Mattos G,. (2014) Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: a translational approach. Psychoneuroendocrinology 49: 229-243.
-
(2014)
Psychoneuroendocrinology
, vol.49
, pp. 229-243
-
-
Heinzmann, J.M.1
Kloiber, S.2
Ebling-Mattos, G.3
-
23
-
-
84926395609
-
Common genetic variants influence human subcortical brain structures
-
Hibar DP, Stein JL, Renteria ME,. (2015) Common genetic variants influence human subcortical brain structures. Nature 520: 224-229.
-
(2015)
Nature
, vol.520
, pp. 224-229
-
-
Hibar, D.P.1
Stein, J.L.2
Renteria, M.E.3
-
24
-
-
84930368102
-
Knowns and unknowns for psychophysiological endophenotypes: integration and response to commentaries
-
Iacono WG, Vaidyanathan U, Vrieze SI,. (2014) Knowns and unknowns for psychophysiological endophenotypes: integration and response to commentaries. Psychophysiology 51: 1339-1347.
-
(2014)
Psychophysiology
, vol.51
, pp. 1339-1347
-
-
Iacono, W.G.1
Vaidyanathan, U.2
Vrieze, S.I.3
-
25
-
-
72449207509
-
Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes
-
Kalueff AV, Olivier JD, Nonkes LJ,. (2010) Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes. Neurosci Biobehav Rev 34: 373-386.
-
(2010)
Neurosci Biobehav Rev
, vol.34
, pp. 373-386
-
-
Kalueff, A.V.1
Olivier, J.D.2
Nonkes, L.J.3
-
27
-
-
84973307170
-
Hidden heritability and genetic parsing of complex CNS disorders
-
Kalueff AV, Poudel MK, Stewart AM, (2015a) Hidden heritability and genetic parsing of complex CNS disorders. Stress Brain Behav 3: 1-2.
-
(2015)
Stress Brain Behav
, vol.3
, pp. 1-2
-
-
Kalueff, A.V.1
Poudel, M.K.2
Stewart, A.M.3
-
28
-
-
84926290665
-
Targeting dynamic interplay among disordered domains or endophenotypes to understand complex neuropsychiatric disorders: Translational lessons from preclinical models
-
Kalueff AV, Stewart AM, Song C, (2015b) Targeting dynamic interplay among disordered domains or endophenotypes to understand complex neuropsychiatric disorders: Translational lessons from preclinical models. Neurosci Biobehav Rev 53: 25-36.
-
(2015)
Neurosci Biobehav Rev
, vol.53
, pp. 25-36
-
-
Kalueff, A.V.1
Stewart, A.M.2
Song, C.3
-
29
-
-
84895528738
-
Targeting neural synchrony deficits is sufficient to improve cognition in a schizophrenia-related neurodevelopmental model
-
Lee H, Dvorak D, Fenton AA, (2014) Targeting neural synchrony deficits is sufficient to improve cognition in a schizophrenia-related neurodevelopmental model. Frontiers Psychiatry 5: 15.
-
(2014)
Frontiers Psychiatry
, vol.5
, pp. 15
-
-
Lee, H.1
Dvorak, D.2
Fenton, A.A.3
-
30
-
-
84883465830
-
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
-
Lee SH, Ripke S, Neale BM,. (2013) Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics 45: 984-994.
-
(2013)
Nature Genetics
, vol.45
, pp. 984-994
-
-
Lee, S.H.1
Ripke, S.2
Neale, B.M.3
-
31
-
-
84905235135
-
Risk of suicidal behavior with antidepressants in bipolar and unipolar disorders
-
Leon AC, Fiedorowicz JG, Solomon DA,. (2014) Risk of suicidal behavior with antidepressants in bipolar and unipolar disorders. J Clin Psychiatry 75: 720-727.
-
(2014)
J Clin Psychiatry
, vol.75
, pp. 720-727
-
-
Leon, A.C.1
Fiedorowicz, J.G.2
Solomon, D.A.3
-
32
-
-
84921626820
-
Integrated systems analysis reveals a molecular network underlying autism spectrum disorders
-
Li J, Shi M, Ma Z,. (2014) Integrated systems analysis reveals a molecular network underlying autism spectrum disorders. Mol Systems Biol 10: 774.
-
(2014)
Mol Systems Biol
, vol.10
, pp. 774
-
-
Li, J.1
Shi, M.2
Ma, Z.3
-
33
-
-
84937838227
-
Developmental white matter microstructure in autism phenotype and corresponding endophenotype during adolescence
-
Lisiecka DM, Holt R, Tait R,. (2015) Developmental white matter microstructure in autism phenotype and corresponding endophenotype during adolescence. Transl Psychiatry 5: e529.
-
(2015)
Transl Psychiatry
, vol.5
, pp. e529
-
-
Lisiecka, D.M.1
Holt, R.2
Tait, R.3
-
34
-
-
84902110446
-
The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder
-
Malki K, Keers R, Tosto MG,. (2014) The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder. BMC Medicine 12: 73.
-
(2014)
BMC Medicine
, vol.12
, pp. 73
-
-
Malki, K.1
Keers, R.2
Tosto, M.G.3
-
35
-
-
84889025030
-
Integrative mouse and human mRNA studies using WGCNA nominates novel candidate genes involved in the pathogenesis of major depressive disorder
-
Malki K, Tosto MG, Jumabhoy I,. (2013) Integrative mouse and human mRNA studies using WGCNA nominates novel candidate genes involved in the pathogenesis of major depressive disorder. Pharmacogenomics 14: 1979-1990.
-
(2013)
Pharmacogenomics
, vol.14
, pp. 1979-1990
-
-
Malki, K.1
Tosto, M.G.2
Jumabhoy, I.3
-
36
-
-
84903991797
-
Medial temporal lobe structures and hippocampal subfields in psychotic disorders: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study
-
Mathew I, Gardin TM, Tandon N,. (2014) Medial temporal lobe structures and hippocampal subfields in psychotic disorders: findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. JAMA Psychiatry 71: 769-777.
-
(2014)
JAMA Psychiatry
, vol.71
, pp. 769-777
-
-
Mathew, I.1
Gardin, T.M.2
Tandon, N.3
-
37
-
-
0141753016
-
Longitudinal trajectories of depression and anxiety in a prospective community study: the Zurich Cohort Study
-
Merikangas KR, Zhang H, Avenevoli S,. (2003) Longitudinal trajectories of depression and anxiety in a prospective community study: the Zurich Cohort Study. Arch Gen Psychiatry 60: 993-1000.
-
(2003)
Arch Gen Psychiatry
, vol.60
, pp. 993-1000
-
-
Merikangas, K.R.1
Zhang, H.2
Avenevoli, S.3
-
38
-
-
84910146166
-
Adolescent angst or true intent? Suicidal behavior, risk, and neurobiological mechanisms in depressed children and teenagers taking antidepressants
-
Morrison J, Schwartz TL, (2014) Adolescent angst or true intent? Suicidal behavior, risk, and neurobiological mechanisms in depressed children and teenagers taking antidepressants. Int J Emergency Mental Health 16: 247-250.
-
(2014)
Int J Emergency Mental Health
, vol.16
, pp. 247-250
-
-
Morrison, J.1
Schwartz, T.L.2
-
39
-
-
77957273984
-
Animal models of neuropsychiatric disorders
-
Nestler EJ, Hyman SE, (2010) Animal models of neuropsychiatric disorders. Nat Neurosci 13: 1161-1169.
-
(2010)
Nat Neurosci
, vol.13
, pp. 1161-1169
-
-
Nestler, E.J.1
Hyman, S.E.2
-
40
-
-
84925844628
-
Attention/vigilance in schizophrenia: Performance results from a large multi-site study of the Consortium on the Genetics of Schizophrenia (COGS)
-
Nuechterlein KH, Green MF, Calkins ME,. (2015) Attention/vigilance in schizophrenia: Performance results from a large multi-site study of the Consortium on the Genetics of Schizophrenia (COGS). Schizophr Res 163: 38-46.
-
(2015)
Schizophr Res
, vol.163
, pp. 38-46
-
-
Nuechterlein, K.H.1
Green, M.F.2
Calkins, M.E.3
-
41
-
-
77953469917
-
Epigenetics as a unifying principle in the aetiology of complex traits and diseases
-
Petronis A, (2010) Epigenetics as a unifying principle in the aetiology of complex traits and diseases. Nature 465: 721-727.
-
(2010)
Nature
, vol.465
, pp. 721-727
-
-
Petronis, A.1
-
42
-
-
84921263296
-
Transitions Study of predictors of illness progression in young people with mental ill health: study methodology
-
Purcell R, Jorm AF, Hickie IB,. (2015) Transitions Study of predictors of illness progression in young people with mental ill health: study methodology. Early Interv Psychiatry 9: 38-47.
-
(2015)
Early Interv Psychiatry
, vol.9
, pp. 38-47
-
-
Purcell, R.1
Jorm, A.F.2
Hickie, I.B.3
-
43
-
-
79957625912
-
Intermediate phenotypes in psychiatric disorders
-
Rasetti R, Weinberger DR, (2011) Intermediate phenotypes in psychiatric disorders. Curr Opin Genet Dev 21: 340-348.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 340-348
-
-
Rasetti, R.1
Weinberger, D.R.2
-
44
-
-
84940735781
-
Overactive performance monitoring as an endophenotype for obsessive-compulsive disorder: Evidence from a treatment study
-
appiajp201414070886
-
Riesel A, Endrass T, Auerbach LA,. (2015) Overactive performance monitoring as an endophenotype for obsessive-compulsive disorder: Evidence from a treatment study. Am J Psychiatry appiajp201414070886.
-
(2015)
Am J Psychiatry
-
-
Riesel, A.1
Endrass, T.2
Auerbach, L.A.3
-
45
-
-
84989339895
-
Behavioural and molecular endophenotypes in psychotic disorders reveal heritable abnormalities in glutamatergic neurotransmission
-
Scoriels L, Salek RM, Goodby E,. (2015) Behavioural and molecular endophenotypes in psychotic disorders reveal heritable abnormalities in glutamatergic neurotransmission. Transl Psychiatry 5: e540.
-
(2015)
Transl Psychiatry
, vol.5
, pp. e540
-
-
Scoriels, L.1
Salek, R.M.2
Goodby, E.3
-
46
-
-
34247509796
-
Epigenetic regulation in psychiatric disorders
-
Tsankova N, Renthal W, Kumar A,. (2007) Epigenetic regulation in psychiatric disorders. Nat Rev Neurosci 8: 355-367.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 355-367
-
-
Tsankova, N.1
Renthal, W.2
Kumar, A.3
-
47
-
-
20444423267
-
Statistical approaches to complex phenotypes: evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder
-
Waldman ID, (2005) Statistical approaches to complex phenotypes: evaluating neuropsychological endophenotypes for attention-deficit/hyperactivity disorder. Biol Psychiatry 57: 1347-1356.
-
(2005)
Biol Psychiatry
, vol.57
, pp. 1347-1356
-
-
Waldman, I.D.1
-
48
-
-
84912059989
-
Computational psychiatry
-
Wang XJ, Krystal JH, (2014) Computational psychiatry. Neuron 84: 638-654.
-
(2014)
Neuron
, vol.84
, pp. 638-654
-
-
Wang, X.J.1
Krystal, J.H.2
|