Targeted or whole genome sequencing of formalin fixed tissue samples: Potential applications in cancer genomics

Oncotarget

Volumn 6, Issue 28, 2015, Pages 25943-25961

  Munchel, Sarah ^a   Hoang, Yen ^b,c   Zhao, Yue ^a   Cottrell, Joseph ^a   Klotzle, Brandy ^a   Godwin, Andrew K ^c   Koestler, Devin ^c   Beyerlein, Peter ^b   Fan, Jian Bing ^a   Bibikova, Marina ^a   Chien, Jeremy ^c  

^a ILLUMINA INC   (United States)

^b TECHNICAL UNIVERSITY OF APPLIED SCIENCES WILDAU   (Germany)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer genomics; Copy number alterations; FFPE DNA; Whole exome sequencing; Whole genome sequencing

Indexed keywords

GENOMIC DNA; PARAFFIN; FORMALDEHYDE;

AMINO ACID SUBSTITUTION; ARTICLE; ARTIFACT; CANCER GENETICS; CANCER TISSUE; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA SEQUENCE; EXOME; EXON; FEMALE; GENE DOSAGE; GENETIC VARIABILITY; GENOME ANALYSIS; HUMAN; HUMAN TISSUE; NEXT GENERATION SEQUENCING; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TARGETED EXON SEQUENCING; WHOLE EXOME SEQUENCING; WHOLE GENOME SEQUENCING; CLUSTER ANALYSIS; FROZEN SECTION; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME; INDEL MUTATION; NEOPLASM; PROCEDURES; REPRODUCIBILITY; STANDARDS; TISSUE FIXATION;

ARTIFACTS; CLUSTER ANALYSIS; DNA COPY NUMBER VARIATIONS; FORMALDEHYDE; FROZEN SECTIONS; GENOME, HUMAN; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INDEL MUTATION; NEOPLASMS; PARAFFIN EMBEDDING; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; TISSUE FIXATION;

EID: 84937847117     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4671     Document Type: Article

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