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Bioorganic and Medicinal Chemistry

Volumn 23, Issue 15, 2015, Pages 4481-4488

Synthesis and biological evaluation of novel histone deacetylases inhibitors with nitric oxide releasing activity

(8) Duan, Wenwen a Hou, Jinning a Chu, Xiaojing b Li, Xiaoqian c Zhang, Jian d Li, Jin a Xu, Wenfang a Zhang, Yingjie a

a SHANDONG UNIVERSITY (China)

b Weifang Bochuang International Biological Medicinal Institute (China)

c Department of Microsurgery (China)

d WEIFANG MEDICAL UNIVERSITY (China)

Author keywords

Benzofuroxan; Epigenetic; HDAC inhibitor; Multifunctional drugs; Nitric oxide

Indexed keywords

4(7) [[(4 HYDROXYAMINO)OXOBUTOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 4(7) [[(5 HYDROXYAMINO)OXOPENTYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 4(7) [[(6 HYDROXYAMINO)OXOHEXYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 4(7) [[(7 HYDROXYAMINO)OXOHEPTYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 4(7) [[(8 HYDROXYAMINO)OXOOCTYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 5(6) [[(4 HYDROXYAMINO)OXOBUTOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 5(6) [[(5 HYDROXYAMINO)OXOPENTYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 5(6) [[(6 HYDROXYAMINO)OXOHEXYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 5(6) [[(7 HYDROXYAMINO)OXOHEPTYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; 5(6) [[(8 HYDROXYAMINO)OXOOCTYLOXY]CARBONYL]BENZO[C][1,2,5]OXADIAZOLE 1 OXIDE; ANTIMITOTIC AGENT; HISTONE DEACETYLASE INHIBITOR; NITRIC OXIDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BENZOFUROXAN; BENZOXAZOLE DERIVATIVE; HEMOGLOBIN; HISTONE DEACETYLASE; OXADIAZOLE DERIVATIVE;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FEMALE; FLUORESCENCE ANALYSIS; HCT116 CELL LINE; HUMAN; HUMAN CELL; NONHUMAN; RAT; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; METABOLISM; SYNTHESIS;

ANTINEOPLASTIC AGENTS; BENZOXAZOLES; CELL PROLIFERATION; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HCT116 CELLS; HEMOGLOBINS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; NITRIC OXIDE; OXADIAZOLES;

EID: 84937817680 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2015.06.015 Document Type: Article

Times cited : (17)

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