Design, synthesis, and antihepatocellular carcinoma activity of nitric oxide releasing derivatives of oleanolic acid

Journal of Medicinal Chemistry

Volumn 51, Issue 15, 2008, Pages 4834-4838

  Chen, Li ^a   Zhang, Yihua ^a   Kong, Xiangwen ^a   Lan, Edward ^b   Huang, Zhangjian ^a   Peng, Sixun ^a   Kaufman, Daniel L ^b   Tian, Jide ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 3 [[5 OXIDO 4 (PHENYLSULFONYL) 1,2,5 OXADIAZOL 3 YL]OXY]PROPYL 3 [(TRIFLUOROACETYL)OXY]OLEAN 12 EN 28 OATE; 1 METHYL 3 [[5 OXIDO 4 (PHENYLSULFONYL) 1,2,5 OXADIAZOL 3 YL]OXY]PROPYL 3 HYDROXYOLEAN 12 EN 28 OATE; 3 [[4 [1 METHYL 3 [[5 OXIDO 4 (PHENYLSULFONYL) 1,2,5 OXADIAZOL 3 YL]OXY]PROPOXY] 4 OXOBUTANOYL]OXY]OLEAN 12 EN 28 OIC ACID; ANTINEOPLASTIC AGENT; NITRIC OXIDE; OLEANOLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIVER CANCER; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE; DRUG DESIGN; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; NITRIC OXIDE; OLEANOLIC ACID;

EID: 49449090229     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800167u     Document Type: Article

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