Catalytic mechanism of a retinoid isomerase essential for vertebrate vision

Nature Chemical Biology

Volumn 11, Issue 6, 2015, Pages 409-415

  Kiser, Philip D ^a   Zhang, Jianye ^a   Badiee, Mohsen ^b   Li, Qingjiang ^b   Shi, Wuxian ^c,d   Sui, Xuewu ^a   Golczak, Marcin ^a   Tochtrop, Gregory P ^b   Palczewski, Krzysztof ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS TRANS ISOMERASE; DIPHENYL ETHER DERIVATIVE; DITERPENE; EMIXUSTAT; LIGAND; PALMITIC ACID DERIVATIVE; PROPANOLAMINE DERIVATIVE; PROTEIN BINDING; RETINOID; RETINOID ISOMEROHYDROLASE; RETINYLAMINE;

ANIMAL; ANTAGONISTS AND INHIBITORS; BINDING SITE; BIOCATALYSIS; C57BL MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; LIGHT; MOLECULAR DOCKING; PHYSIOLOGY; PROTEIN CONFORMATION; RADIATION RESPONSE; RETINAL PIGMENT EPITHELIUM; STEREOISOMERISM; SYNTHESIS; VISION; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; BIOCATALYSIS; CIS-TRANS-ISOMERASES; CRYSTALLOGRAPHY, X-RAY; DITERPENES; LIGANDS; LIGHT; MICE, INBRED C57BL; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; PALMITATES; PHENYL ETHERS; PROPANOLAMINES; PROTEIN BINDING; PROTEIN CONFORMATION; RETINAL PIGMENT EPITHELIUM; RETINOIDS; STEREOISOMERISM; VISION, OCULAR;

EID: 84937764078     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1799     Document Type: Article

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