cCMP and cUMP occur in vivo

Biochemical and Biophysical Research Communications

Volumn 460, Issue 4, 2015, Pages 909-914

  Bähre, Heike ^a   Hartwig, Christina ^a   Munder, Antje ^a   Wolter, Sabine ^a   Stelzer, Tane ^a   Schirmer, Bastian ^a   Beckert, Ulrike ^a   Frank, Dara W ^b   Tümmler, Burkhard ^a   Kaever, Volkhard ^a   Seifert, Roland ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cyclic pyrimidine nucleotides; ExoY; Mass spectrometry; Pseudomonas aeruginosa

Indexed keywords

CYCLIC 3',5'-URIDINE MONOPHOSPHATE; CYCLIC CMP; CYCLIC NUCLEOTIDE; URIDINE PHOSPHATE;

ANIMAL; C57BL MOUSE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MOUSE; REAL TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIC CMP; FEMALE; MICE; MICE, INBRED C57BL; NUCLEOTIDES, CYCLIC; REAL-TIME POLYMERASE CHAIN REACTION; TANDEM MASS SPECTROMETRY; URIDINE MONOPHOSPHATE;

EID: 84937760629     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.03.115     Document Type: Article

References (38)

1. J.M. Gancedo Biological roles of cAMP: variations on a theme in the different kingdoms of life Biol. Rev. Camb. Philos. Soc. 88 2013 645 668
2. J. Schlossmann, and E. Schinner cGMP becomes a drug target Naunyn-Schmiedeberg's Arch. Pharmacol. 385 2012 243 252
3. R.K. Sunahara, and R. Taussig Isoforms of mammalian adenylyl cyclases: multiplicities of signalling Mol. Interv. 2 2002 168 184
4. M. Tresguerres, L.R. Levin, and J. Buck Intracellular cAMP signaling by soluble adenylyl cyclase Kidney Int. 79 2011 1277 1288
5. H. Bähre, K.Y. Danker, and J.P. Stasch Nucleotidyl cyclase activity of soluble guanylyl cyclase in intact cells Biochem. Biophys. Res. Commun. 443 2014 1195 1199
6. A. Hasan, K.Y. Danker, and S. Wolter Soluble adenylyl cyclase accounts for high basal cCMP and cUMP concentrations in HEK293 and B103 cells Biochem. Biophys. Res. Commun. 448 2014 236 240
7. C. Hartwig, H. Bähre, and S. Wolter cAMP, cGMP, cCMP and cUMP concentrations across the tree of life: high cCMP and cUMP levels in astrocytes Neurosci. Lett. 529 2014 183 187
8. U. Beckert, M. Grundmann, and S. Wolter cNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects Biochem. Biophys. Res. Commun. 451 2014 497 502
9. R. Seifert cCMP and cUMP: emerging second messengers Trends Biochem. Sci. 40 2015 8 15
10. R. Seifert, E.H. Schneider, and H. Bähre From canonical to non-canonical second messengers: pharmacological implications Pharmacol. Ther. 148 2015 154 184
11. J.U. Sprenger, and V.O. Nikolaev Biophysical techniques for detection of cAMP and cGMP in living cells Int. J. Mol. Sci. 14 2013 8025 8046
12. F. Gosetti, E. Mazzucco, and D. Zampieri Signal suppression/enhancement in high-performance liquid chromatography tandem mass spectrometry J. Chromatogr. A 1217 2010 3929 3937
13. U. Beckert, W.Y. Aw, and H. Burhenne The receptor-bound guanylyl cyclase DAF-11 is the mediator of hydrogen peroxide-induced cGMP increase in Caenorhabditis elegans PLoS One 8 2013 e72569
14. U. Beckert, S. Wolter, and C. Hartwig ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation Biochem. Biophys. Res. Commun. 450 2014 870 874
15. T.L. Yahr, A.J. Vallis, and M.K. Hancock ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system Proc. Natl. Acad. Sci. U. S. A. 95 1998 13899 13904
16. A. Munder, and B. Tümmler Assessing Pseudomonas virulence using mammalian models: acute infection models Methods Mol. Biol. 1149 2014 773 779
17. K.C. Hess, B.H. Jones, and B. Marquez The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization Dev. Cell. 9 2005 249 259
18. F. Xie, M.A. Garcia, and A.E. Carlson Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization Dev. Biol. 296 2006 353 362
19. 1 Biochemistry 51 2012 194 204
20. T.C. Stevens, C.D. Ochoa, and K.A. Morrow The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury Am. J. Physiol. Lung Cell. Mol. Physiol. 306 2014 L915 L924
21. S. Laue, M. Winterhoff, and V. Kaever cCMP is a substrate for MRP5 Naunyn-Schmiedeberg's Arch. Pharmacol. 387 2014 893 895
22. R.P. Newton, S.G. Salih, and B.J. Salvage Extraction, purification and identification of cytidine 3′,5′-cyclic monophosphate from rat tissues Biochem. J. 221 1984 665 673
23. R.P. Newton, E.E. Kingston, and N.A. Hakeem Extraction, purification, identification and metabolism of 3′,5′-cyclic UMP, 3′,5′-cyclic IMP and 3′,5′-cyclic dTMP from rat tissues Biochem. J. 236 1986 431 439
24. 4 synthesis Agents Actions 32 1991 90 91
25. 4, 2'-O-dibutyryl cytidine 3′:5′-cyclic monophosphate of neutrophil activation Biochem. Biophys. Res. Commun. 174 1991 258 267
26. A. Bloch, G. Dutschman, and R. Maue Cytidine 3′,5′-monophosphate (cyclic CMP). II. Initiation of leukemia L-1210 cell growth in vitro Biochem. Biophys. Res. Commun. 59 1974 955 959
27. 4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo Naunyn-Schmiedeberg's Arch. Pharmacol. 387 2014 1163 1175
28. P.J. Chan The effect of cyclic cytidine 3′,5′-monophosphate (cCMP) on the in vitro development, hatching and attachment of the mouse blastocyst Experientia 43 1987 929 930
29. E.R. Kandel The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB Mol. Brain 5 2012 14
30. P. Sandner, D. Neuser, and E. Bischoff Erectile dysfunction and lower urinary tract Handb. Exp. Pharmacol. 191 2009 507 531
31. I. Buchwalow, J. Schnekenburger, and K. Tiemann L-Arginine-NO-cGMP signaling pathway in pancreatitis Sci. Rep. 3 2013 1899
32. Y. Sassi, and J.S. Hulot Pulmonary hypertension: novel pathways and emerging therapies inhibitors of cGMP and cAMP metabolism Handb. Exp. Pharmacol. 218 2013 513 529
33. R. Brus, Z.S. Herman, and Z. Juraszczyk Central action of cyclic 3′,5′-thymidine, 3′,5′-uridine and 3′,5′-cytidine monophosphates in rat Acta Med. Pol. 25 1984 1 4
34. K.Y. Beste, C.M. Spangler, and H. Burhenne Nucleotidyl cyclase activity of particulate guanylyl cyclase A: comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factor PloS One 8 2013 e70223
35. S.L. Sayner, D.W. Frank, and J. King Paradoxical cAMP-induced lung endothelial hyperpermeability revealed by Pseudomonas aeruginosa ExoY Circ. Res. 95 2004 196 203
36. B.M. Chassy, L.L. Love, and M.I. Krichevsky The acrasin activity of 3′,5′-cyclic nucleotides Proc. Natl. Acad. Sci. U. S. A. 64 1969 296 303
37. P. Albrecht, N. Henke, and M.L. Tien Extracellular cyclic GMP and ist derivatives GMP and guanosine protect from oxidative glutamate toxicity Neurochem. Int. 62 2013 610 619
38. J. Castro, A.M. Harrington, and P.A. Hughes Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3′,5′-monophosphate Gastroenterology 145 2013 1334 1346