메뉴 건너뛰기




Volumn 40, Issue 1, 2015, Pages 8-15

cCMP and cUMP: Emerging second messengers

Author keywords

Bacterial toxins; cCMP; cUMP; Nucleotidyl cyclases; Phosphodiesterases; Protein kinases

Indexed keywords

ADENYLATE CYCLASE INHIBITOR; ADENYLATE CYCLASE TOXIN; BACTERIAL PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC CMP; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE 1; CYCLIC UMP; DIBUTYRYLCYTIDINE 3',5' PHOSPHATE; EDEMA FACTOR; EXOPROTEIN Y; GUANYLATE CYCLASE INHIBITOR; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; MULTIDRUG RESISTANCE PROTEIN; NUCLEOTIDYL CYCLASE TOXIN; ORGANIC ANION TRANSPORTER; PHOSPHODIESTERASE; PURINE; PYRIMIDINE; TOXIN; UNCLASSIFIED DRUG; ADENYLATE CYCLASE; BACTERIAL PROTEINS; BACTERIAL TOXINS; CYCLIC 3',5'-URIDINE MONOPHOSPHATE; EXOY PROTEIN, BACTERIA; GLUCOSYLTRANSFERASES; GUANYLATE CYCLASE; NUCLEOTIDES, CYCLIC; PHOSPHORIC DIESTER HYDROLASES; PROTEIN KINASES; URIDINE MONOPHOSPHATE;

EID: 84925470905     PISSN: 09680004     EISSN: 13624326     Source Type: Journal    
DOI: 10.1016/j.tibs.2014.10.008     Document Type: Review
Times cited : (45)

References (52)
  • 1
    • 0013802478 scopus 로고
    • A cyclic 3',5'-nucleotide phosphodiesterase from heart with specificity for uridine 3',5'-phosphate
    • Hardman J.G., Sutherland E.W. A cyclic 3',5'-nucleotide phosphodiesterase from heart with specificity for uridine 3',5'-phosphate. J. Biol. Chem. 1965, 240:3704-3705.
    • (1965) J. Biol. Chem. , vol.240 , pp. 3704-3705
    • Hardman, J.G.1    Sutherland, E.W.2
  • 2
    • 0014984985 scopus 로고
    • Evidence for a cyclic nucleotide-phosphodiesterase with high specificity for cyclic uridine-3',5'-monophosphate in rat adipose tissue
    • Klotz U., Stock K. Evidence for a cyclic nucleotide-phosphodiesterase with high specificity for cyclic uridine-3',5'-monophosphate in rat adipose tissue. Naunyn Schmiedebergs Arch. Pharmacol. 1971, 269:117-120.
    • (1971) Naunyn Schmiedebergs Arch. Pharmacol. , vol.269 , pp. 117-120
    • Klotz, U.1    Stock, K.2
  • 3
    • 0017709382 scopus 로고
    • Cytidine 3',5'-monophosphate (cyclic CMP) formation in mammalian tissues
    • Cech S.Y., Ignarro L.J. Cytidine 3',5'-monophosphate (cyclic CMP) formation in mammalian tissues. Science 1977, 198:1063-1065.
    • (1977) Science , vol.198 , pp. 1063-1065
    • Cech, S.Y.1    Ignarro, L.J.2
  • 4
    • 0018790489 scopus 로고
    • Cytidylate cyclase: the product isolated by the method of Cech and Ignarro is not cytidine 3',5'-monophosphate
    • Gaion R.M., Krishna G. Cytidylate cyclase: the product isolated by the method of Cech and Ignarro is not cytidine 3',5'-monophosphate. Biochim. Biophys. Res. Commun. 1979, 86:105-111.
    • (1979) Biochim. Biophys. Res. Commun. , vol.86 , pp. 105-111
    • Gaion, R.M.1    Krishna, G.2
  • 5
    • 0020424976 scopus 로고
    • Cyclic cytidine 3',5'-monophosphate (cCMP) in cell regulation
    • Anderson T. Cyclic cytidine 3',5'-monophosphate (cCMP) in cell regulation. Mol. Cell. Endocrinol. 1982, 28:373-385.
    • (1982) Mol. Cell. Endocrinol. , vol.28 , pp. 373-385
    • Anderson, T.1
  • 6
    • 0021233449 scopus 로고
    • Extraction, purification and identification of cytidine 3',5'-cyclic monophosphate from rat tissues
    • Newton R.P., et al. Extraction, purification and identification of cytidine 3',5'-cyclic monophosphate from rat tissues. Biochem. J. 1984, 221:665-673.
    • (1984) Biochem. J. , vol.221 , pp. 665-673
    • Newton, R.P.1
  • 7
    • 84881171832 scopus 로고    scopus 로고
    • Phosphodiesterase-4 inhibitor therapy for lung diseases
    • Beghè B., et al. Phosphodiesterase-4 inhibitor therapy for lung diseases. Am. J. Respir. Crit. Care Med. 2013, 188:271-278.
    • (2013) Am. J. Respir. Crit. Care Med. , vol.188 , pp. 271-278
    • Beghè, B.1
  • 8
    • 84905821185 scopus 로고    scopus 로고
    • Treatment strategies for diabetic patients suffering from erectile dysfunction: an update
    • Redrow G.P., et al. Treatment strategies for diabetic patients suffering from erectile dysfunction: an update. Expert Opin. Pharmacother. 2014, 15:1827-1836.
    • (2014) Expert Opin. Pharmacother. , vol.15 , pp. 1827-1836
    • Redrow, G.P.1
  • 9
    • 2442506761 scopus 로고    scopus 로고
    • Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides
    • Gille A., et al. Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides. J. Biol. Chem. 2004, 279:19955-19969.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19955-19969
    • Gille, A.1
  • 10
    • 34548315751 scopus 로고    scopus 로고
    • Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides
    • Göttle M., et al. Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides. Mol. Pharmacol. 2007, 72:526-535.
    • (2007) Mol. Pharmacol. , vol.72 , pp. 526-535
    • Göttle, M.1
  • 11
    • 77954178718 scopus 로고    scopus 로고
    • Cytidylyl and uridylyl cyclase activity of Bacillus anthracis edema factor and Bordetella pertussis CyaA
    • Göttle M., et al. Cytidylyl and uridylyl cyclase activity of Bacillus anthracis edema factor and Bordetella pertussis CyaA. Biochemistry 2010, 49:5494-5503.
    • (2010) Biochemistry , vol.49 , pp. 5494-5503
    • Göttle, M.1
  • 12
    • 84864364923 scopus 로고    scopus 로고
    • Bacillus anthracis edema factor substrate specificity: evidence for new modes of action
    • Göttle M., et al. Bacillus anthracis edema factor substrate specificity: evidence for new modes of action. Toxins 2012, 4:505-535.
    • (2012) Toxins , vol.4 , pp. 505-535
    • Göttle, M.1
  • 13
    • 31844435261 scopus 로고    scopus 로고
    • Bordetella adenylate cyclase toxin: a swift saboteur of host defense
    • Vojtova J., et al. Bordetella adenylate cyclase toxin: a swift saboteur of host defense. Curr. Opin. Microbiol. 2006, 9:69-75.
    • (2006) Curr. Opin. Microbiol. , vol.9 , pp. 69-75
    • Vojtova, J.1
  • 15
    • 84883169940 scopus 로고    scopus 로고
    • The receptor-bound guanylyl cyclase DAF-11 is the mediator of hydrogen peroxide-induced cGMP increase in Caenorhabditis elegans
    • Beckert U., et al. The receptor-bound guanylyl cyclase DAF-11 is the mediator of hydrogen peroxide-induced cGMP increase in Caenorhabditis elegans. PLoS ONE 2013, 8:e72569.
    • (2013) PLoS ONE , vol.8
    • Beckert, U.1
  • 16
    • 84893728687 scopus 로고    scopus 로고
    • Nucleotidyl cyclase activity of soluble guanylyl cyclase in intact cells
    • Bähre H., et al. Nucleotidyl cyclase activity of soluble guanylyl cyclase in intact cells. Biochem. Biophys. Res. Commun. 2014, 443:1195-1199.
    • (2014) Biochem. Biophys. Res. Commun. , vol.443 , pp. 1195-1199
    • Bähre, H.1
  • 17
    • 84907336003 scopus 로고    scopus 로고
    • CAMP, cGMP, cCMP and cUMP concentrations across the tree of life: high cCMP and cUMP levels in astrocytes
    • Hartwig C., et al. cAMP, cGMP, cCMP and cUMP concentrations across the tree of life: high cCMP and cUMP levels in astrocytes. Neurosci. Lett. 2014, 579:183-187.
    • (2014) Neurosci. Lett. , vol.579 , pp. 183-187
    • Hartwig, C.1
  • 18
    • 84901608228 scopus 로고    scopus 로고
    • Soluble adenylyl cyclase accounts for the high basal cCMP and cUMP concentrations in HEK293 and B103 cells
    • Hasan A., et al. Soluble adenylyl cyclase accounts for the high basal cCMP and cUMP concentrations in HEK293 and B103 cells. Biochem. Biophys. Res. Commun. 2014, 448:236-240.
    • (2014) Biochem. Biophys. Res. Commun. , vol.448 , pp. 236-240
    • Hasan, A.1
  • 19
    • 33645287748 scopus 로고    scopus 로고
    • Soluble adenylyl cyclase reveals the significance of cAMP compartmentation on pulmonary microvascular endothelial cell barrier
    • Sayner S.L., et al. Soluble adenylyl cyclase reveals the significance of cAMP compartmentation on pulmonary microvascular endothelial cell barrier. Circ. Res. 2006, 98:675-6781.
    • (2006) Circ. Res. , vol.98 , pp. 675-6781
    • Sayner, S.L.1
  • 20
    • 84919337973 scopus 로고    scopus 로고
    • Structure, mechanism, and regulation of soluble adenylyl cyclases - similarities and differences to transmembrane adenylyl cyclases
    • Published online September 2, 2014
    • Steegborn C. Structure, mechanism, and regulation of soluble adenylyl cyclases - similarities and differences to transmembrane adenylyl cyclases. Biochim. Biophys. Acta 2014, Published online September 2, 2014. 10.1016/j.bbadis.2014.08.012.
    • (2014) Biochim. Biophys. Acta
    • Steegborn, C.1
  • 21
    • 84863621407 scopus 로고    scopus 로고
    • Binding of regulatory subunits of cyclic AMP-dependent protein kinase to cyclic CMP agarose
    • Hammerschmidt A., et al. Binding of regulatory subunits of cyclic AMP-dependent protein kinase to cyclic CMP agarose. PLoS ONE 2012, 7:e39848.
    • (2012) PLoS ONE , vol.7
    • Hammerschmidt, A.1
  • 22
    • 84855880193 scopus 로고    scopus 로고
    • Differential activation of cAMP- and cGMP-dependent protein kinases by cyclic purine and pyrimidine nucleotides
    • Wolter S., et al. Differential activation of cAMP- and cGMP-dependent protein kinases by cyclic purine and pyrimidine nucleotides. Biochem. Biophys. Res. Commun. 2011, 415:563-566.
    • (2011) Biochem. Biophys. Res. Commun. , vol.415 , pp. 563-566
    • Wolter, S.1
  • 23
    • 84908701308 scopus 로고    scopus 로고
    • PDE7A1 hdrolyzes cCMP
    • Monzel M., et al. PDE7A1 hdrolyzes cCMP. FEBS Lett. 2014, 588:3469-3474.
    • (2014) FEBS Lett. , vol.588 , pp. 3469-3474
    • Monzel, M.1
  • 24
    • 84908373339 scopus 로고    scopus 로고
    • CNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects
    • Beckert U., et al. cNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects. Biochem. Biophys. Res. Commun. 2014, 451:497-502.
    • (2014) Biochem. Biophys. Res. Commun. , vol.451 , pp. 497-502
    • Beckert, U.1
  • 25
    • 84912550563 scopus 로고    scopus 로고
    • 4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo
    • (in press)
    • 4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo. Naunyn-Schmiedebergs Arch. Pharmacol. 2014, (in press).
    • (2014) Naunyn-Schmiedebergs Arch. Pharmacol.
    • Wolter, S.1
  • 26
    • 77956908953 scopus 로고    scopus 로고
    • Cyclic cytidine 3',5'-monophosphate (cCMP) signals via cGMP kinase I
    • Desch M., et al. Cyclic cytidine 3',5'-monophosphate (cCMP) signals via cGMP kinase I. FEBS Lett. 2010, 584:3979-3984.
    • (2010) FEBS Lett. , vol.584 , pp. 3979-3984
    • Desch, M.1
  • 27
    • 84864531090 scopus 로고    scopus 로고
    • Regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel activity by cCMP
    • Zong X., et al. Regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel activity by cCMP. J. Biol. Chem. 2012, 287:26506-26512.
    • (2012) J. Biol. Chem. , vol.287 , pp. 26506-26512
    • Zong, X.1
  • 28
    • 84905836722 scopus 로고    scopus 로고
    • A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP
    • Akimoto M., et al. A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP. J. Biol. Chem. 2014, 289:22205-22220.
    • (2014) J. Biol. Chem. , vol.289 , pp. 22205-22220
    • Akimoto, M.1
  • 29
    • 80054064690 scopus 로고    scopus 로고
    • Human cyclic nucleotide phosphodiesterases possess a much broader substrate-specificity than previously appreciated
    • Reinecke D., et al. Human cyclic nucleotide phosphodiesterases possess a much broader substrate-specificity than previously appreciated. FEBS Lett. 2011, 585:3259-3262.
    • (2011) FEBS Lett. , vol.585 , pp. 3259-3262
    • Reinecke, D.1
  • 30
    • 33748686575 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use
    • Bender A.T., Beavo J.A. Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol. Rev. 2006, 58:488-520.
    • (2006) Pharmacol. Rev. , vol.58 , pp. 488-520
    • Bender, A.T.1    Beavo, J.A.2
  • 32
    • 0033801452 scopus 로고    scopus 로고
    • Cyclic nucleotide analogs as biochemical tools and prospective drugs
    • Schwede F., et al. Cyclic nucleotide analogs as biochemical tools and prospective drugs. Pharmacol. Ther. 2000, 87:199-226.
    • (2000) Pharmacol. Ther. , vol.87 , pp. 199-226
    • Schwede, F.1
  • 33
    • 0027942378 scopus 로고
    • Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility
    • Schultz C., et al. Membrane-permeant derivatives of cyclic AMP optimized for high potency, prolonged activity, or rapid reversibility. Mol. Pharmacol. 1994, 46:702-708.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 702-708
    • Schultz, C.1
  • 34
    • 84880804862 scopus 로고    scopus 로고
    • Nucleotidyl cyclase activity of particulate guanylyl cyclase A: Comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factor
    • Beste K.Y., et al. Nucleotidyl cyclase activity of particulate guanylyl cyclase A: Comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factor. PLoS ONE 2013, 8:e70223.
    • (2013) PLoS ONE , vol.8
    • Beste, K.Y.1
  • 35
    • 84904719123 scopus 로고    scopus 로고
    • ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation
    • Beckert U., et al. ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation. Biochem. Biophys. Res. Commun. 2014, 450:870-874.
    • (2014) Biochem. Biophys. Res. Commun. , vol.450 , pp. 870-874
    • Beckert, U.1
  • 36
    • 0032506004 scopus 로고    scopus 로고
    • ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system
    • Yahr T.L., et al. ExoY, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:13899-13904.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 13899-13904
    • Yahr, T.L.1
  • 37
    • 84864081350 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa exotoxin Y is a promiscuous cyclase that increases endothelial tau phosphorylation and permeability
    • Ochoa C.D., et al. Pseudomonas aeruginosa exotoxin Y is a promiscuous cyclase that increases endothelial tau phosphorylation and permeability. J. Biol. Chem. 2012, 287:25407-25418.
    • (2012) J. Biol. Chem. , vol.287 , pp. 25407-25418
    • Ochoa, C.D.1
  • 38
    • 15544380187 scopus 로고    scopus 로고
    • Activities of Pseudomonas aeruginosa effectors secreted by the type III secretion system in vitro and during infection
    • Lee V.T., et al. Activities of Pseudomonas aeruginosa effectors secreted by the type III secretion system in vitro and during infection. Infect. Immun. 2005, 73:1695-1705.
    • (2005) Infect. Immun. , vol.73 , pp. 1695-1705
    • Lee, V.T.1
  • 39
    • 84900807344 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury
    • Stevens T.C., et al. The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury. Am. J. Physiol. Lung Cell. Mol. Physiol. 2014, 306:L915-L924.
    • (2014) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.306 , pp. L915-L924
    • Stevens, T.C.1
  • 40
    • 0025924062 scopus 로고
    • 4, 2'-O-dibutyryl cytidine 3':5'-cyclic monophosphate of neutrophil activation
    • 4, 2'-O-dibutyryl cytidine 3':5'-cyclic monophosphate of neutrophil activation. Biochem. Biophys. Res. Commun. 1991, 174:258-267.
    • (1991) Biochem. Biophys. Res. Commun. , vol.174 , pp. 258-267
    • Ervens, J.1    Seifert, R.2
  • 41
    • 0025775112 scopus 로고
    • 2, 2'-O-dibutyryl guanosine 3':5'-cyclic monophosphate
    • 2, 2'-O-dibutyryl guanosine 3':5'-cyclic monophosphate. Naunyn-Schmiedebergs Arch. Pharmacol. 1991, 343:370-376.
    • (1991) Naunyn-Schmiedebergs Arch. Pharmacol. , vol.343 , pp. 370-376
    • Ervens, J.1
  • 42
    • 0023655667 scopus 로고
    • The effect of cyclic cytidine 3',5'-monophosphate (cCMP) on the in vitro development, hatching and attachment of the mouse blastocyst
    • Chan P.J. The effect of cyclic cytidine 3',5'-monophosphate (cCMP) on the in vitro development, hatching and attachment of the mouse blastocyst. Experientia 1987, 43:929-930.
    • (1987) Experientia , vol.43 , pp. 929-930
    • Chan, P.J.1
  • 43
    • 0023807279 scopus 로고
    • Regulation of mouse trophoblast giant cell nucleus development in hatched mouse blastocysts by cyclic cytidine 3',5'-monophosphate (cCMP)
    • Chan P.J., et al. Regulation of mouse trophoblast giant cell nucleus development in hatched mouse blastocysts by cyclic cytidine 3',5'-monophosphate (cCMP). Experientia 1988, 44:774-775.
    • (1988) Experientia , vol.44 , pp. 774-775
    • Chan, P.J.1
  • 44
    • 84895091713 scopus 로고    scopus 로고
    • Responses to Pseudomonas aeruginosa to antimicrobials
    • Morita Y., et al. Responses to Pseudomonas aeruginosa to antimicrobials. Front. Microbiol. 2014, 4:422.
    • (2014) Front. Microbiol. , vol.4 , pp. 422
    • Morita, Y.1
  • 45
    • 84911934947 scopus 로고    scopus 로고
    • Assessing Pseudomonas virulence with the nonmammalian host model: Arabidopsis thaliana
    • Baldini R.L., et al. Assessing Pseudomonas virulence with the nonmammalian host model: Arabidopsis thaliana. Methods Mol. Biol. 2014, 1149:689-697.
    • (2014) Methods Mol. Biol. , vol.1149 , pp. 689-697
    • Baldini, R.L.1
  • 47
    • 84877074699 scopus 로고    scopus 로고
    • Biophysical techniques for detection of cAMP and cGMP in living cells
    • Sprenger J.U., Nikolaev V.O. Biophysical techniques for detection of cAMP and cGMP in living cells. Int. J. Mol. Sci. 2013, 14:8025-8046.
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 8025-8046
    • Sprenger, J.U.1    Nikolaev, V.O.2
  • 48
    • 84898907292 scopus 로고    scopus 로고
    • Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in mice
    • Ziolo K.J., et al. Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in mice. Infect. Immun. 2014, 82:2148-2157.
    • (2014) Infect. Immun. , vol.82 , pp. 2148-2157
    • Ziolo, K.J.1
  • 49
    • 2342573008 scopus 로고    scopus 로고
    • The extracellular cyclic AMP-adenosine pathway in renal physiology
    • Jackson E.K., Raghvendra D.K. The extracellular cyclic AMP-adenosine pathway in renal physiology. Annu. Rev. Physiol. 2004, 66:571-599.
    • (2004) Annu. Rev. Physiol. , vol.66 , pp. 571-599
    • Jackson, E.K.1    Raghvendra, D.K.2
  • 50
    • 0014564707 scopus 로고
    • The acrasin activity of 3',5'-cyclic nucleotides
    • Chassy B.M., et al. The acrasin activity of 3',5'-cyclic nucleotides. Proc. Natl. Acad. Sci. U.S.A. 1969, 64:296-303.
    • (1969) Proc. Natl. Acad. Sci. U.S.A. , vol.64 , pp. 296-303
    • Chassy, B.M.1
  • 51
    • 84872243626 scopus 로고    scopus 로고
    • G protein coupled receptor deorphanizations
    • Civelli O., et al. G protein coupled receptor deorphanizations. Annu. Rev. Pharmacol. Toxicol. 2013, 53:127-146.
    • (2013) Annu. Rev. Pharmacol. Toxicol. , vol.53 , pp. 127-146
    • Civelli, O.1
  • 52
    • 84873899865 scopus 로고    scopus 로고
    • Mining the potential of label-free biosensors for seven-transmembrane receptor drug discovery
    • Rocheville M., et al. Mining the potential of label-free biosensors for seven-transmembrane receptor drug discovery. Prog. Mol. Biol. Transl. Sci. 2013, 115:123-142.
    • (2013) Prog. Mol. Biol. Transl. Sci. , vol.115 , pp. 123-142
    • Rocheville, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.