-
3
-
-
84892695519
-
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease
-
Salloway S, Sperling R, Fox NC, et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med 2014;370:322–333.
-
(2014)
N Engl J Med
, vol.370
, pp. 322-333
-
-
Salloway, S.1
Sperling, R.2
Fox, N.C.3
-
4
-
-
0028982454
-
Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease
-
Motter R, Vigo-Pelfrey C, Kholodenko D, et al. Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol 1995;38:643–648.
-
(1995)
Ann Neurol
, vol.38
, pp. 643-648
-
-
Motter, R.1
Vigo-Pelfrey, C.2
Kholodenko, D.3
-
5
-
-
10744232413
-
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
-
Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol 2004;55:306–319.
-
(2004)
Ann Neurol
, vol.55
, pp. 306-319
-
-
Klunk, W.E.1
Engler, H.2
Nordberg, A.3
-
6
-
-
32544435900
-
Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study
-
Hansson O, Zetterberg H, Buchhave P, et al. Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study. Lancet Neurol 2006;5:228–234.
-
(2006)
Lancet Neurol
, vol.5
, pp. 228-234
-
-
Hansson, O.1
Zetterberg, H.2
Buchhave, P.3
-
7
-
-
49349092320
-
PET imaging of amyloid deposition in patients with mild cognitive impairment
-
Forsberg A, Engler H, Almkvist O, et al. PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiol Aging 2008;29:1456–1465.
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1456-1465
-
-
Forsberg, A.1
Engler, H.2
Almkvist, O.3
-
8
-
-
34247219169
-
Cerebrospinal fluid beta-amyloid 1-42 concentration may predict cognitive decline in older women
-
Gustafson DR, Skoog I, Rosengren L, et al. Cerebrospinal fluid beta-amyloid 1-42 concentration may predict cognitive decline in older women. J Neurol Neurosurg Psychiatry 2007;78:461–464.
-
(2007)
J Neurol Neurosurg Psychiatry
, vol.78
, pp. 461-464
-
-
Gustafson, D.R.1
Skoog, I.2
Rosengren, L.3
-
9
-
-
73549092137
-
Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease
-
Morris JC, Roe CM, Grant EA, et al. Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease. Arch Neurol 2009;66:1469–1475.
-
(2009)
Arch Neurol
, vol.66
, pp. 1469-1475
-
-
Morris, J.C.1
Roe, C.M.2
Grant, E.A.3
-
10
-
-
34447322271
-
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria
-
Dubois B, Feldman HH, Jacova C, et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 2007;6:734–746.
-
(2007)
Lancet Neurol
, vol.6
, pp. 734-746
-
-
Dubois, B.1
Feldman, H.H.2
Jacova, C.3
-
11
-
-
79956142378
-
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011;7:263–269.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 263-269
-
-
McKhann, G.M.1
Knopman, D.S.2
Chertkow, H.3
-
12
-
-
79956084514
-
The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011;7:270–279.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 270-279
-
-
Albert, M.S.1
DeKosky, S.T.2
Dickson, D.3
-
13
-
-
84892918273
-
Comparing PET imaging and CSF measurements of Aß
-
Landau SM, Lu M, Joshi AD, et al. Comparing PET imaging and CSF measurements of Aß. Ann Neurol 2013;74:826–36.
-
(2013)
Ann Neurol
, vol.74
, pp. 826-836
-
-
Landau, S.M.1
Lu, M.2
Joshi, A.D.3
-
14
-
-
33947223454
-
Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
-
Fagan AM, Roe CM, Xiong C, et al. Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol 2007;64:343–349.
-
(2007)
Arch Neurol
, vol.64
, pp. 343-349
-
-
Fagan, A.M.1
Roe, C.M.2
Xiong, C.3
-
15
-
-
77949425172
-
Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease
-
Fagan AM, Mintun MA, Shah AR, et al. Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease. EMBO Mol Med 2009;1:371–380.
-
(2009)
EMBO Mol Med
, vol.1
, pp. 371-380
-
-
Fagan, A.M.1
Mintun, M.A.2
Shah, A.R.3
-
16
-
-
70350152831
-
Relationships between biomarkers in aging and dementia
-
Jagust WJ, Landau SM, Shaw LM, et al. Relationships between biomarkers in aging and dementia. Neurology 2009;73:1193–1199.
-
(2009)
Neurology
, vol.73
, pp. 1193-1199
-
-
Jagust, W.J.1
Landau, S.M.2
Shaw, L.M.3
-
17
-
-
77949555201
-
Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: an exploratory study
-
Degerman Gunnarsson M, Lindau M, Wall A, et al. Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: an exploratory study. Dement Geriatr Cogn Disord 29:204–212.
-
Dement Geriatr Cogn Disord
, vol.29
, pp. 204-212
-
-
Degerman Gunnarsson, M.1
Lindau, M.2
Wall, A.3
-
18
-
-
79952740168
-
Transforming CSF Aβ42 measures into calculated Pittsburgh Compound B (PIBcalc) units of brain Aβ amyloid
-
Weigand SD, Vemuri P, Wiste HJ, et al. Transforming CSF Aβ42 measures into calculated Pittsburgh Compound B (PIBcalc) units of brain Aβ amyloid. Alzheimers Dement 2011;7:133–141.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 133-141
-
-
Weigand, S.D.1
Vemuri, P.2
Wiste, H.J.3
-
19
-
-
69449085355
-
Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding
-
Tolboom N, van der Flier WM, Yaqub M, et al. Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding. J Nucl Med 2009;50:1464–1470.
-
(2009)
J Nucl Med
, vol.50
, pp. 1464-1470
-
-
Tolboom, N.1
van der Flier, W.M.2
Yaqub, M.3
-
20
-
-
84862735174
-
Amyloid deposition, hypometabolism, and longitudinal cognitive decline
-
Landau SM, Mintun MA, Joshi AD, et al. Amyloid deposition, hypometabolism, and longitudinal cognitive decline. Ann Neurol 2012;72:578–586.
-
(2012)
Ann Neurol
, vol.72
, pp. 578-586
-
-
Landau, S.M.1
Mintun, M.A.2
Joshi, A.D.3
-
21
-
-
12944312683
-
Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology
-
Olsson A, Vanderstichele H, Andreasen N, et al. Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology. Clin Chem 2005;51:336–345.
-
(2005)
Clin Chem
, vol.51
, pp. 336-345
-
-
Olsson, A.1
Vanderstichele, H.2
Andreasen, N.3
-
22
-
-
65249159879
-
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
-
Shaw LM, Vanderstichele H, Knapik-Czajka M, et al. Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects. Ann Neurol 2009;65:403–413.
-
(2009)
Ann Neurol
, vol.65
, pp. 403-413
-
-
Shaw, L.M.1
Vanderstichele, H.2
Knapik-Czajka, M.3
-
23
-
-
84858591462
-
Performance characteristics of amyloid PET with florbetapir F 18 in patients with alzheimer's disease and cognitively normal subjects
-
Joshi AD, Pontecorvo MJ, Clark CM, et al. Performance characteristics of amyloid PET with florbetapir F 18 in patients with alzheimer's disease and cognitively normal subjects. J Nucl Med 2012;53:378–384.
-
(2012)
J Nucl Med
, vol.53
, pp. 378-384
-
-
Joshi, A.D.1
Pontecorvo, M.J.2
Clark, C.M.3
-
24
-
-
78751546481
-
Use of florbetapir-PET for imaging beta-amyloid pathology
-
Clark CM, Schneider JA, Bedell BJ, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA 2011;305:275–283.
-
(2011)
JAMA
, vol.305
, pp. 275-283
-
-
Clark, C.M.1
Schneider, J.A.2
Bedell, B.J.3
-
25
-
-
73549123897
-
Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report
-
Cairns NJ, Ikonomovic MD, Benzinger T, et al. Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report. Arch Neurol 2009;66:1557–1562.
-
(2009)
Arch Neurol
, vol.66
, pp. 1557-1562
-
-
Cairns, N.J.1
Ikonomovic, M.D.2
Benzinger, T.3
-
26
-
-
84887218458
-
A 2-process model for neuropathology of Alzheimer's disease
-
Mungas D, Tractenberg R, Schneider JA, et al. A 2-process model for neuropathology of Alzheimer's disease. Neurobiol Aging 2014;35:301–308.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 301-308
-
-
Mungas, D.1
Tractenberg, R.2
Schneider, J.A.3
-
27
-
-
84878860533
-
Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections
-
Krut JJ, Zetterberg H, Blennow K, et al. Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections. J Neurol 2013;260:620–626.
-
(2013)
J Neurol
, vol.260
, pp. 620-626
-
-
Krut, J.J.1
Zetterberg, H.2
Blennow, K.3
-
28
-
-
84876552168
-
Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple sclerosis
-
Augutis K, Axelsson M, Portelius E, et al. Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple sclerosis. Mult Scler 2013;19:543–552.
-
(2013)
Mult Scler
, vol.19
, pp. 543-552
-
-
Augutis, K.1
Axelsson, M.2
Portelius, E.3
-
29
-
-
84873681445
-
A selected reaction monitoring (SRM)-based method for absolute quantification of Aβ38, Aβ40, and Aβ42 in cerebrospinal fluid of Alzheimer's Disease patients and healthy controls
-
Pannee J, Portelius E, Oppermann M, et al. A selected reaction monitoring (SRM)-based method for absolute quantification of Aβ38, Aβ40, and Aβ42 in cerebrospinal fluid of Alzheimer's Disease patients and healthy controls. J Alzheimers Dis 2013;33:1021–1032.
-
(2013)
J Alzheimers Dis
, vol.33
, pp. 1021-1032
-
-
Pannee, J.1
Portelius, E.2
Oppermann, M.3
-
30
-
-
84865452551
-
Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid beta42
-
Mattsson N, Zegers I, Andreasson U, et al. Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid beta42. Biomark Med 2012;6:409–417.
-
(2012)
Biomark Med
, vol.6
, pp. 409-417
-
-
Mattsson, N.1
Zegers, I.2
Andreasson, U.3
-
31
-
-
77954033257
-
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
-
Rowe CC, Ellis KA, Rimajova M, et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging 2010;31:1275–1283.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1275-1283
-
-
Rowe, C.C.1
Ellis, K.A.2
Rimajova, M.3
-
32
-
-
84884127276
-
Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study
-
Vos SJ, Xiong C, Visser PJ, et al. Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study. Lancet Neurol 2013;12:957–965.
-
(2013)
Lancet Neurol
, vol.12
, pp. 957-965
-
-
Vos, S.J.1
Xiong, C.2
Visser, P.J.3
-
33
-
-
84892765470
-
Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease
-
Lim YY, Maruff P, Pietrzak RH, et al. Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer's disease. Brain 2014;137(Pt 1):221–231.
-
(2014)
Brain
, vol.137
, pp. 221-231
-
-
Lim, Y.Y.1
Maruff, P.2
Pietrzak, R.H.3
-
34
-
-
84856732033
-
Neuroimaging results impose new views on Alzheimer's disease – the role of amyloid revised
-
Fjell AM, Walhovd KB. Neuroimaging results impose new views on Alzheimer's disease – the role of amyloid revised. Mol Neurobiol 2012;45:153–172.
-
(2012)
Mol Neurobiol
, vol.45
, pp. 153-172
-
-
Fjell, A.M.1
Walhovd, K.B.2
-
35
-
-
72049130805
-
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
-
Jack CR, Knopman DS, Jagust WJ, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 2010;9:119–128.
-
(2010)
Lancet Neurol
, vol.9
, pp. 119-128
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
-
36
-
-
84855304100
-
Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia
-
Buchhave P, Minthon L, Zetterberg H, et al. Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia. Arch Gen Psychiatry 2012;69:98–106.
-
(2012)
Arch Gen Psychiatry
, vol.69
, pp. 98-106
-
-
Buchhave, P.1
Minthon, L.2
Zetterberg, H.3
-
37
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Sperling RA, Aisen PS, Beckett LA, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011;7:280–292.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
|