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Volumn 370, Issue 4, 2014, Pages 377-378

Antiamyloid therapy for Alzheimer's disease - Are we on the right road?

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN ANTIBODY; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN A4; BAPINEUZUMAB; SOLANEZUMAB; TAU PROTEIN;

EID: 84892710970     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1313943     Document Type: Editorial
Times cited : (105)

References (7)
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    • Hardy, J.1    Selkoe, D.J.2
  • 2
    • 84892695519 scopus 로고    scopus 로고
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    • Salloway S, Sperling R, Fox NC, et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med 2014;370:322-33.
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    • Salloway, S.1    Sperling, R.2    Fox, N.C.3
  • 3
    • 84892748542 scopus 로고    scopus 로고
    • Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease
    • Doody RS, Thomas RG, Farlow M, et al. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease. N Engl J Med 2014;370:311-21.
    • (2014) N Engl J Med , vol.370 , pp. 311-321
    • Doody, R.S.1    Thomas, R.G.2    Farlow, M.3
  • 4
    • 84872144291 scopus 로고    scopus 로고
    • A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice
    • Demattos RB, Lu J, Tang Y, et al. A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice. Neuron 2012;76:908-20.
    • (2012) Neuron , vol.76 , pp. 908-920
    • Demattos, R.B.1    Lu, J.2    Tang, Y.3
  • 5
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    • Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein
    • Maia LF, Kaeser SA, Reichwald J, et al. Changes in amyloid-β and Tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein. Sci Transl Med 2013;5(194): 194re2.
    • (2013) Sci Transl Med , vol.5 , Issue.194
    • Maia, L.F.1    Kaeser, S.A.2    Reichwald, J.3
  • 6
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
    • DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 2001;98: 8850-5.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8850-8855
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Dodart, J.C.4    Paul, S.M.5    Holtzman, D.M.6
  • 7
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    • The amyloid cascade hypothesis for Alzheimer's disease: An appraisal for the development of therapeutics
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.