Synthesis of new ent-labdane diterpene derivatives from andrographolide and evaluation on cytotoxic activities

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 11, 2015, Pages 2421-2424

  Luo, Yan ^a   Wang, Ke ^b   Zhang, Meng Han ^b   Zhang, Da Yong ^b   Wu, Yang Chang ^c   Wu, Xiao Ming ^b   Hua, Wei Yi ^b  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Andrographolide; Cytotoxic activity; ent Labdane diterpene; SAR

Indexed keywords

ANDROGRAPHOLIDE; ANTINEOPLASTIC AGENT; DITERPENE;

CHEMICAL STRUCTURE; CHEMISTRY; DRUG DEVELOPMENT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTINEOPLASTIC AGENTS; DITERPENES; DRUG DISCOVERY; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84937758442     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.03.086     Document Type: Article

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