New substituted C-19-andrographolide analogues with potent cytotoxic activities

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 49-52

  Sirion, Uthaiwan ^a   Kasemsook, Sakkasem ^a   Suksen, Kanoknetr ^b   Piyachaturawat, Pawinee ^b   Suksamrarn, Apichart ^c   Saeeng, Rungnapha ^a  

^a BURAPHA UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c RAMKHAMHAENG UNIVERSITY   (Thailand)

Author keywords

19 O Triphenylmethylandrographolide; Andrographolide; Cytotoxicity; Structure modification

Indexed keywords

19 O TRIPHENYLMETHYLANDROGRAPHOLIDE; ANDROGRAPHOLIDE; ANTINEOPLASTIC AGENT; ELLIPTICINE; ETHER; HYDROXYL GROUP; SILANE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANDROGRAPHIS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DITERPENES; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; LACTONES; MODELS, CHEMICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

ANDROGRAPHIS PANICULATA;

EID: 84655167794     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.11.085     Document Type: Article

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