-
2
-
-
13344261952
-
T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients
-
Riddell, S. R., M. Elliott, D. A. Lewinsohn, M. J. Gilbert, L. Wilson, S. A. Manley, S. D. Lupton, R.W. Overell, T. C. Reynolds, L. Corey, and P. D. Greenberg. 1996. T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients. Nat. Med. 2: 216-223.
-
(1996)
Nat. Med.
, vol.2
, pp. 216-223
-
-
Riddell, S.R.1
Elliott, M.2
Lewinsohn, D.A.3
Gilbert, M.J.4
Wilson, L.5
Manley, S.A.6
Lupton, S.D.7
Overell, R.W.8
Reynolds, T.C.9
Corey, L.10
Greenberg, P.D.11
-
3
-
-
84860718270
-
Decade-long safety and function of retroviralmodified chimeric antigen receptor T cells
-
Scholler, J., T. Brady, G. Binder-Scholl, W.-T. Hwang, G. Plesa, K. Hege, A. Vogel, M. Kalos, J. Riley, S. Deeks, et al. 2012. Decade-long safety and function of retroviralmodified chimeric antigen receptor T cells. Sci. Transl. Med. 4: 132ra153.
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 132ra153
-
-
Scholler, J.1
Brady, T.2
Binder-Scholl, G.3
Hwang, W.-T.4
Plesa, G.5
Hege, K.6
Vogel, A.7
Kalos, M.8
Riley, J.9
Deeks, S.10
-
4
-
-
84886769508
-
Replicationcompetent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
-
Ho, Y. C., L. Shan, N. N. Hosmane, J. Wang, S. B. Laskey, D. I. Rosenbloom, J. Lai, J. N. Blankson, J. D. Siliciano, and R. F. Siliciano. 2013. Replicationcompetent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell 155: 540-551.
-
(2013)
Cell
, vol.155
, pp. 540-551
-
-
Ho, Y.C.1
Shan, L.2
Hosmane, N.N.3
Wang, J.4
Laskey, S.B.5
Rosenbloom, D.I.6
Lai, J.7
Blankson, J.N.8
Siliciano, J.D.9
Siliciano, R.F.10
-
5
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
-
Hütter, G., D. Nowak, M. Mossner, S. Ganepola, A. Müssig, K. Allers, T. Schneider, J. Hofmann, C. Kücherer, O. Blau, et al. 2009. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N. Engl. J. Med. 360: 692-698.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 692-698
-
-
Hütter, G.1
Nowak, D.2
Mossner, M.3
Ganepola, S.4
Müssig, A.5
Allers, K.6
Schneider, T.7
Hofmann, J.8
Kücherer, C.9
Blau, O.10
-
7
-
-
84922764937
-
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
-
Deng, K., M. Pertea, A. Rongvaux, L. Wang, C. M. Durand, G. Ghiaur, J. Lai, H. L. McHugh, H. Hao, H. Zhang, et al. 2015. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations. Nature 517: 381-385.
-
(2015)
Nature
, vol.517
, pp. 381-385
-
-
Deng, K.1
Pertea, M.2
Rongvaux, A.3
Wang, L.4
Durand, C.M.5
Ghiaur, G.6
Lai, J.7
McHugh, H.L.8
Hao, H.9
Zhang, H.10
-
8
-
-
0037093217
-
The infusion of ex vivo activated and expanded CD4+CD25+ immune regulatory cells inhibits graft-versus-host disease lethality
-
Taylor, P. A., C. J. Lees, and B. R. Blazar. 2002. The infusion of ex vivo activated and expanded CD4+CD25+ immune regulatory cells inhibits graft-versus-host disease lethality. Blood 99: 3493-3499.
-
(2002)
Blood
, vol.99
, pp. 3493-3499
-
-
Taylor, P.A.1
Lees, C.J.2
Blazar, B.R.3
-
9
-
-
2942642383
-
In vitro-expanded antigenspecific regulatory T cells suppress autoimmune diabetes
-
Tang, Q., K. J. Henriksen, M. Bi, E. B. Finger, G. Szot, J. Ye, E. L. Masteller, H. McDevitt, M. Bonyhadi, and J. A. Bluestone. 2004. In vitro-expanded antigenspecific regulatory T cells suppress autoimmune diabetes. J. Exp. Med. 199: 1455-1465.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
Masteller, E.L.7
McDevitt, H.8
Bonyhadi, M.9
Bluestone, J.A.10
-
10
-
-
78751696183
-
Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: Safety profile and detection kinetics
-
Brunstein, C. G., J. S. Miller, Q. Cao, D. H. McKenna, K. L. Hippen, J. Curtsinger, T. Defor, B. L. Levine, C. H. June, P. Rubinstein, et al. 2011. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics. Blood 117: 1061-1070.
-
(2011)
Blood
, vol.117
, pp. 1061-1070
-
-
Brunstein, C.G.1
Miller, J.S.2
Cao, Q.3
McKenna, D.H.4
Hippen, K.L.5
Curtsinger, J.6
Defor, T.7
Levine, B.L.8
June, C.H.9
Rubinstein, P.10
-
11
-
-
79956258982
-
Massive ex vivo expansion of human natural regulatory T cells (Tregs) with minimal loss of in vivo functional activity
-
Hippen, K. L., S. C. Merkel, D. K. Schirm, C. M. Sieben, D. Sumstad, D. M. Kadidlo, D. H. McKenna, J. S. Bromberg, B. L. Levine, J. L. Riley, et al. 2011. Massive ex vivo expansion of human natural regulatory T cells (Tregs) with minimal loss of in vivo functional activity. Sci. Transl. Med. 3: 83ra41.
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 83ra41
-
-
Hippen, K.L.1
Merkel, S.C.2
Schirm, D.K.3
Sieben, C.M.4
Sumstad, D.5
Kadidlo, D.M.6
McKenna, D.H.7
Bromberg, J.S.8
Levine, B.L.9
Riley, J.L.10
-
12
-
-
79958814636
-
Generation and largescale expansion of human inducible regulatory T cells that suppress graft-versus-host disease
-
Hippen, K. L., S. C. Merkel, D. K. Schirm, C. Nelson, N. C. Tennis, J. L. Riley, C. H. June, J. S. Miller, J. E. Wagner, and B. R. Blazar. 2011. Generation and largescale expansion of human inducible regulatory T cells that suppress graft-versus-host disease. Am. J. Transplant. 11: 1148-1157.
-
(2011)
Am. J. Transplant.
, vol.11
, pp. 1148-1157
-
-
Hippen, K.L.1
Merkel, S.C.2
Schirm, D.K.3
Nelson, C.4
Tennis, N.C.5
Riley, J.L.6
June, C.H.7
Miller, J.S.8
Wagner, J.E.9
Blazar, B.R.10
-
13
-
-
77951158406
-
Protein kinase C-u mediates negative feedback on regulatory T cell function
-
Zanin-Zhorov, A., Y. Ding, S. Kumari, M. Attur, K. L. Hippen, M. Brown, B. R. Blazar, S. B. Abramson, J. J. Lafaille, and M. L. Dustin. 2010. Protein kinase C-u mediates negative feedback on regulatory T cell function. Science 328: 372-376.
-
(2010)
Science
, vol.328
, pp. 372-376
-
-
Zanin-Zhorov, A.1
Ding, Y.2
Kumari, S.3
Attur, M.4
Hippen, K.L.5
Brown, M.6
Blazar, B.R.7
Abramson, S.B.8
Lafaille, J.J.9
Dustin, M.L.10
-
14
-
-
14944371830
-
Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes
-
Mekala, D. J., and T. L. Geiger. 2005. Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Blood 105: 2090-2092.
-
(2005)
Blood
, vol.105
, pp. 2090-2092
-
-
Mekala, D.J.1
Geiger, T.L.2
-
15
-
-
49149083788
-
Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-z chimeric receptor
-
Moisini, I., P. Nguyen, L. Fugger, and T. L. Geiger. 2008. Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-z chimeric receptor. J. Immunol. 180: 3601-3611.
-
(2008)
J. Immunol.
, vol.180
, pp. 3601-3611
-
-
Moisini, I.1
Nguyen, P.2
Fugger, L.3
Geiger, T.L.4
-
16
-
-
65549127618
-
Human T regulatory cell therapy: Take a billion or so and call me in the morning
-
Riley, J. L., C. H. June, and B. R. Blazar. 2009. Human T regulatory cell therapy: take a billion or so and call me in the morning. Immunity 30: 656-665.
-
(2009)
Immunity
, vol.30
, pp. 656-665
-
-
Riley, J.L.1
June, C.H.2
Blazar, B.R.3
-
17
-
-
70349969840
-
Regulatory T cells as therapeutic targets in rheumatoid arthritis
-
Esensten, J. H., D. Wofsy, and J. A. Bluestone. 2009. Regulatory T cells as therapeutic targets in rheumatoid arthritis. Nat Rev Rheumatol 5: 560-565.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 560-565
-
-
Esensten, J.H.1
Wofsy, D.2
Bluestone, J.A.3
-
18
-
-
84890104932
-
Use of gene-modified regulatory T-cells to control autoimmune and alloimmune pathology: Is now the right time?
-
Jethwa, H., A. A. Adami, and J. Maher. 2014. Use of gene-modified regulatory T-cells to control autoimmune and alloimmune pathology: is now the right time? Clin. Immunol. 150: 51-63.
-
(2014)
Clin. Immunol.
, vol.150
, pp. 51-63
-
-
Jethwa, H.1
Adami, A.A.2
Maher, J.3
-
19
-
-
0029134048
-
In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes
-
Hwu, P., J. C. Yang, R. Cowherd, J. Treisman, G. E. Shafer, Z. Eshhar, and S. A. Rosenberg. 1995. In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes. Cancer Res. 55: 3369-3373.
-
(1995)
Cancer Res.
, vol.55
, pp. 3369-3373
-
-
Hwu, P.1
Yang, J.C.2
Cowherd, R.3
Treisman, J.4
Shafer, G.E.5
Eshhar, Z.6
Rosenberg, S.A.7
-
20
-
-
84897960533
-
Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy
-
Barrett, D. M., N. Singh, X. Liu, S. Jiang, C. H. June, S. A. Grupp, and Y. Zhao. 2014. Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy. Cytotherapy 16: 619-630.
-
(2014)
Cytotherapy
, vol.16
, pp. 619-630
-
-
Barrett, D.M.1
Singh, N.2
Liu, X.3
Jiang, S.4
June, C.H.5
Grupp, S.A.6
Zhao, Y.7
-
21
-
-
84893562519
-
Chimeric antigen receptor therapy for cancer
-
Barrett, D. M., N. Singh, D. L. Porter, S. A. Grupp, and C. H. June. 2014. Chimeric antigen receptor therapy for cancer. Annu. Rev. Med. 65: 333-347.
-
(2014)
Annu. Rev. Med.
, vol.65
, pp. 333-347
-
-
Barrett, D.M.1
Singh, N.2
Porter, D.L.3
Grupp, S.A.4
June, C.H.5
-
22
-
-
34848842554
-
Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts
-
Brentjens, R. J., E. Santos, Y. Nikhamin, R. Yeh, M. Matsushita, K. La Perle, A. Quintás-Cardama, S. M. Larson, and M. Sadelain. 2007. Genetically targeted T cells eradicate systemic acute lymphoblastic leukemia xenografts. Clin. Cancer Res. 13: 5426-5435.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5426-5435
-
-
Brentjens, R.J.1
Santos, E.2
Nikhamin, Y.3
Yeh, R.4
Matsushita, M.5
La Perle, K.6
Quintás-Cardama, A.7
Larson, S.M.8
Sadelain, M.9
-
23
-
-
79954573204
-
In vivo inhibition of human CD19-targeted effector T cells by natural T regulatory cells in a xenotransplant murine model of B cell malignancy
-
Lee, J. C., E. Hayman, H. J. Pegram, E. Santos, G. Heller, M. Sadelain, and R. Brentjens. 2011. In vivo inhibition of human CD19-targeted effector T cells by natural T regulatory cells in a xenotransplant murine model of B cell malignancy. Cancer Res. 71: 2871-2881.
-
(2011)
Cancer Res.
, vol.71
, pp. 2871-2881
-
-
Lee, J.C.1
Hayman, E.2
Pegram, H.J.3
Santos, E.4
Heller, G.5
Sadelain, M.6
Brentjens, R.7
-
24
-
-
84888226232
-
T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia
-
Mardiros, A., C. Dos Santos, T. McDonald, C. E. Brown, X. Wang, L. E. Budde, L. Hoffman, B. Aguilar, W. C. Chang, W. Bretzlaff, et al. 2013. T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia. Blood 122: 3138-3148.
-
(2013)
Blood
, vol.122
, pp. 3138-3148
-
-
Mardiros, A.1
Dos Santos, C.2
McDonald, T.3
Brown, C.E.4
Wang, X.5
Budde, L.E.6
Hoffman, L.7
Aguilar, B.8
Chang, W.C.9
Bretzlaff, W.10
-
25
-
-
70350726110
-
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo
-
Milone, M. C., J. D. Fish, C. Carpenito, R. G. Carroll, G. K. Binder, D. Teachey, M. Samanta, M. Lakhal, B. Gloss, G. Danet-Desnoyers, et al. 2009. Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol. Ther. 17: 1453-1464.
-
(2009)
Mol. Ther.
, vol.17
, pp. 1453-1464
-
-
Milone, M.C.1
Fish, J.D.2
Carpenito, C.3
Carroll, R.G.4
Binder, G.K.5
Teachey, D.6
Samanta, M.7
Lakhal, M.8
Gloss, B.9
Danet-Desnoyers, G.10
-
26
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp, S. A., M. Kalos, D. Barrett, R. Aplenc, D. L. Porter, S. R. Rheingold, D. T. Teachey, A. Chew, B. Hauck, J. F. Wright, et al. 2013. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N. Engl. J. Med. 368: 1509-1518.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
Aplenc, R.4
Porter, D.L.5
Rheingold, S.R.6
Teachey, D.T.7
Chew, A.8
Hauck, B.9
Wright, J.F.10
-
27
-
-
84908073316
-
Chimeric antigen receptor T cells for sustained remissions in leukemia
-
Maude, S., N. Frey, P. Shaw, R. Aplenc, D. Barrett, N. Bunin, A. Chew, V. Gonzalez, Z. Zheng, S. Lacey, et al. 2014. Chimeric antigen receptor T cells for sustained remissions in leukemia. N. Engl. J. Med. 371: 1507-1517.
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 1507-1517
-
-
Maude, S.1
Frey, N.2
Shaw, P.3
Aplenc, R.4
Barrett, D.5
Bunin, N.6
Chew, A.7
Gonzalez, V.8
Zheng, Z.9
Lacey, S.10
-
28
-
-
84876050411
-
CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia
-
Davila, M. L., C. C. Kloss, G. Gunset, and M. Sadelain. 2013. CD19 CAR-targeted T cells induce long-term remission and B cell aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia. PLoS ONE 8: e61338.
-
(2013)
PLoS ONE
, vol.8
, pp. e61338
-
-
Davila, M.L.1
Kloss, C.C.2
Gunset, G.3
Sadelain, M.4
-
29
-
-
77957756405
-
Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells
-
Kochenderfer, J. N., Z. Yu, D. Frasheri, N. P. Restifo, and S. A. Rosenberg. 2010. Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells. Blood 116: 3875-3886.
-
(2010)
Blood
, vol.116
, pp. 3875-3886
-
-
Kochenderfer, J.N.1
Yu, Z.2
Frasheri, D.3
Restifo, N.P.4
Rosenberg, S.A.5
-
30
-
-
84858759305
-
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
-
Pegram, H. J., J. C. Lee, E. G. Hayman, G. H. Imperato, T. F. Tedder, M. Sadelain, and R. J. Brentjens. 2012. Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning. Blood 119: 4133-4141.
-
(2012)
Blood
, vol.119
, pp. 4133-4141
-
-
Pegram, H.J.1
Lee, J.C.2
Hayman, E.G.3
Imperato, G.H.4
Tedder, T.F.5
Sadelain, M.6
Brentjens, R.J.7
-
31
-
-
84900850997
-
Development and function of human innate immune cells in a humanized mouse model
-
Rongvaux, A., T. Willinger, J. Martinek, T. Strowig, S. V. Gearty, L. L. Teichmann, Y. Saito, F. Marches, S. Halene, A. K. Palucka, et al. 2014. Development and function of human innate immune cells in a humanized mouse model. Nat. Biotechnol. 32: 364-372.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 364-372
-
-
Rongvaux, A.1
Willinger, T.2
Martinek, J.3
Strowig, T.4
Gearty, S.V.5
Teichmann, L.L.6
Saito, Y.7
Marches, F.8
Halene, S.9
Palucka, A.K.10
-
32
-
-
84885991395
-
Preclinical in vivo modeling of cytokine release syndrome induced by ErbBretargeted human T cells: Identifying a window of therapeutic opportunity?
-
van der Stegen, S. J., D. M. Davies, S. Wilkie, J. Foster, J. K. Sosabowski, J. Burnet, L. M. Whilding, R. M. Petrovic, S. Ghaem-Maghami, S. Mather, et al. 2013. Preclinical in vivo modeling of cytokine release syndrome induced by ErbBretargeted human T cells: identifying a window of therapeutic opportunity? J. Immunol. 191: 4589-4598.
-
(2013)
J. Immunol.
, vol.191
, pp. 4589-4598
-
-
Van Der Stegen, S.J.1
Davies, D.M.2
Wilkie, S.3
Foster, J.4
Sosabowski, J.K.5
Burnet, J.6
Whilding, L.M.7
Petrovic, R.M.8
Ghaem-Maghami, S.9
Mather, S.10
-
33
-
-
0026064305
-
The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-Associated signal transduction pathways
-
Irving, B. A., and A. Weiss. 1991. The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-Associated signal transduction pathways. Cell 64: 891-901.
-
(1991)
Cell
, vol.64
, pp. 891-901
-
-
Irving, B.A.1
Weiss, A.2
-
34
-
-
0026083035
-
Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides
-
Romeo, C., and B. Seed. 1991. Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides. Cell 64: 1037-1046.
-
(1991)
Cell
, vol.64
, pp. 1037-1046
-
-
Romeo, C.1
Seed, B.2
-
35
-
-
0025998529
-
T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins
-
Letourneur, F., and R. D. Klausner. 1991. T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins. Proc. Natl. Acad. Sci. USA 88: 8905-8909.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 8905-8909
-
-
Letourneur, F.1
Klausner, R.D.2
-
36
-
-
0023568155
-
Expression of chimeric receptor composed of immunoglobulin-derived v regions and T-cell receptor-derived C regions
-
Kuwana, Y., Y. Asakura, N. Utsunomiya, M. Nakanishi, Y. Arata, S. Itoh, F. Nagase, and Y. Kurosawa. 1987. Expression of chimeric receptor composed of immunoglobulin-derived V regions and T-cell receptor-derived C regions. Biochem. Biophys. Res. Commun. 149: 960-968.
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.149
, pp. 960-968
-
-
Kuwana, Y.1
Asakura, Y.2
Utsunomiya, N.3
Nakanishi, M.4
Arata, Y.5
Itoh, S.6
Nagase, F.7
Kurosawa, Y.8
-
39
-
-
62549097817
-
Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
-
Carpenito, C., M. C. Milone, R. Hassan, J. C. Simonet, M. Lakhal, M. M. Suhoski, A. Varela-Rohena, K. M. Haines, D. F. Heitjan, S. M. Albelda, et al. 2009. Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains. Proc. Natl. Acad. Sci. USA 106: 3360-3365.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 3360-3365
-
-
Carpenito, C.1
Milone, M.C.2
Hassan, R.3
Simonet, J.C.4
Lakhal, M.5
Suhoski, M.M.6
Varela-Rohena, A.7
Haines, K.M.8
Heitjan, D.F.9
Albelda, S.M.10
-
40
-
-
84896335556
-
Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
-
Davila, M. L., I. Riviere, X. Wang, S. Bartido, J. Park, K. Curran, S. S. Chung, J. Stefanski, O. Borquez-Ojeda, M. Olszewska, et al. 2014. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci. Transl. Med. 6: 224ra25.
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 224ra25
-
-
Davila, M.L.1
Riviere, I.2
Wang, X.3
Bartido, S.4
Park, J.5
Curran, K.6
Chung, S.S.7
Stefanski, J.8
Borquez-Ojeda, O.9
Olszewska, M.10
-
41
-
-
84930765209
-
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
-
Long, A. H., W. M. Haso, J. F. Shern, K. M. Wanhainen, M. Murgai, M. Ingaramo, J. P. Smith, A. J. Walker, M. E. Kohler, V. R. Venkateshwara, et al. 2015. 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors. Nat. Med. 21: 581-590.
-
(2015)
Nat. Med.
, vol.21
, pp. 581-590
-
-
Long, A.H.1
Haso, W.M.2
Shern, J.F.3
Wanhainen, K.M.4
Murgai, M.5
Ingaramo, M.6
Smith, J.P.7
Walker, A.J.8
Kohler, M.E.9
Venkateshwara, V.R.10
-
42
-
-
84962213143
-
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells
-
Frigault, M. J., J. Lee, M. C. Basil, C. Carpenito, S. Motohashi, J. Scholler, O. U. Kawalekar, S. Guedan, S. E. McGettigan, A. D. Posey, Jr., et al. 2015. Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells. Cancer Immunol Res 3: 356-367.
-
(2015)
Cancer Immunol Res
, vol.3
, pp. 356-367
-
-
Frigault, M.J.1
Lee, J.2
Basil, M.C.3
Carpenito, C.4
Motohashi, S.5
Scholler, J.6
Kawalekar, O.U.7
Guedan, S.8
McGettigan, S.E.9
Posey, A.D.10
-
43
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter, D. L., B. L. Levine, M. Kalos, A. Bagg, and C. H. June. 2011. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N. Engl. J. Med. 365: 725-733.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
44
-
-
78549278144
-
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
-
Kochenderfer, J. N., W. H. Wilson, J. E. Janik, M. E. Dudley, M. Stetler-Stevenson, S. A. Feldman, I. Maric, M. Raffeld, D. A. Nathan, B. J. Lanier, et al. 2010. Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19. Blood 116: 4099-4102.
-
(2010)
Blood
, vol.116
, pp. 4099-4102
-
-
Kochenderfer, J.N.1
Wilson, W.H.2
Janik, J.E.3
Dudley, M.E.4
Stetler-Stevenson, M.5
Feldman, S.A.6
Maric, I.7
Raffeld, M.8
Nathan, D.A.9
Lanier, B.J.10
-
45
-
-
84897568616
-
Managing cytokine release syndrome associated with novel T cell-engaging therapies
-
Maude, S. L., D. Barrett, D. T. Teachey, and S. A. Grupp. 2014. Managing cytokine release syndrome associated with novel T cell-engaging therapies. Cancer J. 20: 119-122.
-
(2014)
Cancer J.
, vol.20
, pp. 119-122
-
-
Maude, S.L.1
Barrett, D.2
Teachey, D.T.3
Grupp, S.A.4
-
46
-
-
84904097189
-
Current concepts in the diagnosis and management of cytokine release syndrome
-
Lee, D. W., R. Gardner, D. L. Porter, C. U. Louis, N. Ahmed, M. Jensen, S. A. Grupp, and C. L. Mackall. 2014. Current concepts in the diagnosis and management of cytokine release syndrome. Blood 124: 188-195.
-
(2014)
Blood
, vol.124
, pp. 188-195
-
-
Lee, D.W.1
Gardner, R.2
Porter, D.L.3
Louis, C.U.4
Ahmed, N.5
Jensen, M.6
Grupp, S.A.7
Mackall, C.L.8
-
47
-
-
84882782587
-
Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy
-
Teachey, D. T., S. R. Rheingold, S. L. Maude, G. Zugmaier, D. M. Barrett, A. E. Seif, K. E. Nichols, E. K. Suppa, M. Kalos, R. A. Berg, et al. 2013. Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy. Blood 121: 5154-5157.
-
(2013)
Blood
, vol.121
, pp. 5154-5157
-
-
Teachey, D.T.1
Rheingold, S.R.2
Maude, S.L.3
Zugmaier, G.4
Barrett, D.M.5
Seif, A.E.6
Nichols, K.E.7
Suppa, E.K.8
Kalos, M.9
Berg, R.A.10
-
48
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos, M., B. L. Levine, D. L. Porter, S. Katz, S. A. Grupp, A. Bagg, and C. H. June. 2011. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci. Transl. Med. 3: 95ra73.
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 95ra73
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
Katz, S.4
Grupp, S.A.5
Bagg, A.6
June, C.H.7
-
49
-
-
77950475517
-
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
-
Morgan, R. A., J. C. Yang, M. Kitano, M. E. Dudley, C. M. Laurencot, and S. A. Rosenberg. 2010. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol. Ther. 18: 843-851.
-
(2010)
Mol. Ther.
, vol.18
, pp. 843-851
-
-
Morgan, R.A.1
Yang, J.C.2
Kitano, M.3
Dudley, M.E.4
Laurencot, C.M.5
Rosenberg, S.A.6
-
50
-
-
84880730689
-
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
-
Linette, G. P., E. A. Stadtmauer, M. V. Maus, A. P. Rapoport, B. L. Levine, L. Emery, L. Litzky, A. Bagg, B. M. Carreno, P. J. Cimino, et al. 2013. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood 122: 863-871.
-
(2013)
Blood
, vol.122
, pp. 863-871
-
-
Linette, G.P.1
Stadtmauer, E.A.2
Maus, M.V.3
Rapoport, A.P.4
Levine, B.L.5
Emery, L.6
Litzky, L.7
Bagg, A.8
Carreno, B.M.9
Cimino, P.J.10
-
51
-
-
84883866836
-
Identification of a Titinderived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells
-
Cameron, B. J., A. B. Gerry, J. Dukes, J. V. Harper, V. Kannan, F. C. Bianchi, F. Grand, J. E. Brewer, M. Gupta, G. Plesa, et al. 2013. Identification of a Titinderived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells. Sci. Transl. Med. 5: 197ra103.
-
(2013)
Sci. Transl. Med.
, vol.5
, pp. 197ra103
-
-
Cameron, B.J.1
Gerry, A.B.2
Dukes, J.3
Harper, J.V.4
Kannan, V.5
Bianchi, F.C.6
Grand, F.7
Brewer, J.E.8
Gupta, M.9
Plesa, G.10
-
52
-
-
84873991752
-
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
-
Morgan, R. A., N. Chinnasamy, D. Abate-Daga, A. Gros, P. F. Robbins, Z. Zheng, M. E. Dudley, S. A. Feldman, J. C. Yang, R. M. Sherry, et al. 2013. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. J. Immunother. 36: 133-151.
-
(2013)
J. Immunother.
, vol.36
, pp. 133-151
-
-
Morgan, R.A.1
Chinnasamy, N.2
Abate-Daga, D.3
Gros, A.4
Robbins, P.F.5
Zheng, Z.6
Dudley, M.E.7
Feldman, S.A.8
Yang, J.C.9
Sherry, R.M.10
-
53
-
-
84923019006
-
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: A phase 1 dose-escalation trial
-
Lee, D. W., J. N. Kochenderfer, M. Stetler-Stevenson, Y. K. Cui, C. Delbrook, S. A. Feldman, T. J. Fry, R. Orentas, M. Sabatino, N. N. Shah, et al. 2015. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial. Lancet 385: 517-528.
-
(2015)
Lancet
, vol.385
, pp. 517-528
-
-
Lee, D.W.1
Kochenderfer, J.N.2
Stetler-Stevenson, M.3
Cui, Y.K.4
Delbrook, C.5
Feldman, S.A.6
Fry, T.J.7
Orentas, R.8
Sabatino, M.9
Shah, N.N.10
-
54
-
-
67650360757
-
Rapid immune recovery and graft-versus-host disease-like engraftment syndrome following adoptive transfer of costimulated autologous T cells
-
Rapoport, A. P., E. A. Stadtmauer, N. Aqui, D. Vogl, A. Chew, H. B. Fang, S. Janofsky, K. Yager, E. Veloso, Z. Zheng, et al. 2009. Rapid immune recovery and graft-versus-host disease-like engraftment syndrome following adoptive transfer of costimulated autologous T cells. Clin. Cancer Res. 15: 4499-4507.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 4499-4507
-
-
Rapoport, A.P.1
Stadtmauer, E.A.2
Aqui, N.3
Vogl, D.4
Chew, A.5
Fang, H.B.6
Janofsky, S.7
Yager, K.8
Veloso, E.9
Zheng, Z.10
-
55
-
-
84871256981
-
Adoptive transfer of autologous T cells improves T-cell repertoire diversity and long-term B-cell function in pediatric patients with neuroblastoma
-
Grupp, S. A., E. L. Prak, J. Boyer, K. R. McDonald, S. Shusterman, E. Thompson, C. Callahan, A. F. Jawad, B. L. Levine, C. H. June, and K. E. Sullivan. 2012. Adoptive transfer of autologous T cells improves T-cell repertoire diversity and long-term B-cell function in pediatric patients with neuroblastoma. Clin. Cancer Res. 18: 6732-6741.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 6732-6741
-
-
Grupp, S.A.1
Prak, E.L.2
Boyer, J.3
McDonald, K.R.4
Shusterman, S.5
Thompson, E.6
Callahan, C.7
Jawad, A.F.8
Levine, B.L.9
June, C.H.10
Sullivan, K.E.11
-
56
-
-
84876172359
-
Comparison of different suicide-gene strategies for the safety improvement of genetically manipulated T cells
-
Marin, V., E. Cribioli, B. Philip, S. Tettamanti, I. Pizzitola, A. Biondi, E. Biagi, and M. Pule. 2012. Comparison of different suicide-gene strategies for the safety improvement of genetically manipulated T cells. Hum. Gene. Ther. Methods 23: 376-386.
-
(2012)
Hum. Gene. Ther. Methods
, vol.23
, pp. 376-386
-
-
Marin, V.1
Cribioli, E.2
Philip, B.3
Tettamanti, S.4
Pizzitola, I.5
Biondi, A.6
Biagi, E.7
Pule, M.8
-
57
-
-
1342303482
-
Of mice and not men: Differences between mouse and human immunology
-
Mestas, J., and C. C. Hughes. 2004. Of mice and not men: differences between mouse and human immunology. J. Immunol. 172: 2731-2738.
-
(2004)
J. Immunol.
, vol.172
, pp. 2731-2738
-
-
Mestas, J.1
Hughes, C.C.2
-
58
-
-
84856831733
-
T-cell receptor gene therapy in human melanoma-bearing immune-deficient mice: Human but not mouse T cells recapitulate outcome of clinical studies
-
Straetemans, T., M. Coccoris, C. Berrevoets, E. Treffers-Westerlaken, C. E. Scholten, D. Schipper, T. L. Ten Hagen, and R. Debets. 2012. T-cell receptor gene therapy in human melanoma-bearing immune-deficient mice: human but not mouse T cells recapitulate outcome of clinical studies. Hum. Gene Ther. 23: 187-201.
-
(2012)
Hum. Gene Ther.
, vol.23
, pp. 187-201
-
-
Straetemans, T.1
Coccoris, M.2
Berrevoets, C.3
Treffers-Westerlaken, E.4
Scholten, C.E.5
Schipper, D.6
Ten Hagen, T.L.7
Debets, R.8
-
59
-
-
0028848829
-
Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation
-
Abe, R., P. Vandenberghe, N. Craighead, D. S. Smoot, K. P. Lee, and C. H. June. 1995. Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation. J. Immunol. 154: 985-997.
-
(1995)
J. Immunol.
, vol.154
, pp. 985-997
-
-
Abe, R.1
Vandenberghe, P.2
Craighead, N.3
Smoot, D.S.4
Lee, K.P.5
June, C.H.6
-
60
-
-
2442714006
-
Extensive replicative capacity of human central memory T cells
-
Maus, M. V., B. Kovacs, W. W. Kwok, G. T. Nepom, K. Schlienger, J. L. Riley, D. Allman, T. H. Finkel, and C. H. June. 2004. Extensive replicative capacity of human central memory T cells. J. Immunol. 172: 6675-6683.
-
(2004)
J. Immunol.
, vol.172
, pp. 6675-6683
-
-
Maus, M.V.1
Kovacs, B.2
Kwok, W.W.3
Nepom, G.T.4
Schlienger, K.5
Riley, J.L.6
Allman, D.7
Finkel, T.H.8
June, C.H.9
-
61
-
-
38149117105
-
Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates
-
Berger, C., M. C. Jensen, P. M. Lansdorp, M. Gough, C. Elliott, and S. R. Riddell. 2008. Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates. J. Clin. Invest. 118: 294-305.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 294-305
-
-
Berger, C.1
Jensen, M.C.2
Lansdorp, P.M.3
Gough, M.4
Elliott, C.5
Riddell, S.R.6
-
62
-
-
84880733312
-
Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology
-
Kalos, M., and C. H. June. 2013. Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology. Immunity 39: 49-60.
-
(2013)
Immunity
, vol.39
, pp. 49-60
-
-
Kalos, M.1
June, C.H.2
-
63
-
-
0036909464
-
A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes
-
Thomas, A. K., M. V. Maus, W. S. Shalaby, C. H. June, and J. L. Riley. 2002. A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes. Clin. Immunol. 105: 259-272.
-
(2002)
Clin. Immunol.
, vol.105
, pp. 259-272
-
-
Thomas, A.K.1
Maus, M.V.2
Shalaby, W.S.3
June, C.H.4
Riley, J.L.5
-
64
-
-
60849098427
-
IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes
-
Kaneko, S., S. Mastaglio, A. Bondanza, M. Ponzoni, F. Sanvito, L. Aldrighetti, M. Radrizzani, S. La Seta-Catamancio, E. Provasi, A. Mondino, et al. 2009. IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes. Blood 113: 1006-1015.
-
(2009)
Blood
, vol.113
, pp. 1006-1015
-
-
Kaneko, S.1
Mastaglio, S.2
Bondanza, A.3
Ponzoni, M.4
Sanvito, F.5
Aldrighetti, L.6
Radrizzani, M.7
La Seta-Catamancio, S.8
Provasi, E.9
Mondino, A.10
-
65
-
-
0036171757
-
Ex vivo expansion of polyclonal and antigenspecific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB
-
Maus, M. V., A. K. Thomas, D. G. Leonard, D. Allman, K. Addya, K. Schlienger, J. L. Riley, and C. H. June. 2002. Ex vivo expansion of polyclonal and antigenspecific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB. Nat. Biotechnol. 20: 143-148.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 143-148
-
-
Maus, M.V.1
Thomas, A.K.2
Leonard, D.G.3
Allman, D.4
Addya, K.5
Schlienger, K.6
Riley, J.L.7
June, C.H.8
-
66
-
-
78049518331
-
The inducible costimulator (ICOS) is critical for the development of human TH17 cells
-
Paulos, C. M., C. Carpenito, G. Plesa, M. M. Suhoski, A. Varela-Rohena, T. N. Golovina, R. G. Carroll, J. L. Riley, and C. H. June. 2010. The inducible costimulator (ICOS) is critical for the development of human TH17 cells. Sci. Transl. Med. 2: 55ra78.
-
(2010)
Sci. Transl. Med.
, vol.2
, pp. 55ra78
-
-
Paulos, C.M.1
Carpenito, C.2
Plesa, G.3
Suhoski, M.M.4
Varela-Rohena, A.5
Golovina, T.N.6
Carroll, R.G.7
Riley, J.L.8
June, C.H.9
-
67
-
-
80053997259
-
A human memory T cell subset with stem cell-like properties
-
Gattinoni, L., E. Lugli, Y. Ji, Z. Pos, C. M. Paulos, M. F. Quigley, J. R. Almeida, E. Gostick, Z. Yu, C. Carpenito, et al. 2011. A human memory T cell subset with stem cell-like properties. Nat. Med. 17: 1290-1297.
-
(2011)
Nat. Med.
, vol.17
, pp. 1290-1297
-
-
Gattinoni, L.1
Lugli, E.2
Ji, Y.3
Pos, Z.4
Paulos, C.M.5
Quigley, M.F.6
Almeida, J.R.7
Gostick, E.8
Yu, Z.9
Carpenito, C.10
-
68
-
-
84904394259
-
Serial transfer of singlecell-derived immunocompetence reveals stemness of CD8+ central memory T cells
-
Graef, P., V. R. Buchholz, C. Stemberger, M. Flossdorf, L. Henkel, M. Schiemann, I. Drexler, T. Höfer, S. R. Riddell, and D. H. Busch. 2014. Serial transfer of singlecell-derived immunocompetence reveals stemness of CD8+ central memory T cells. Immunity 41: 116-126.
-
(2014)
Immunity
, vol.41
, pp. 116-126
-
-
Graef, P.1
Buchholz, V.R.2
Stemberger, C.3
Flossdorf, M.4
Henkel, L.5
Schiemann, M.6
Drexler, I.7
Höfer, T.8
Riddell, S.R.9
Busch, D.H.10
-
69
-
-
67650465237
-
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
-
Gattinoni, L., X. S. Zhong, D. C. Palmer, Y. Ji, C. S. Hinrichs, Z. Yu, C. Wrzesinski, A. Boni, L. Cassard, L. M. Garvin, et al. 2009. Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells. Nat. Med. 15: 808-813.
-
(2009)
Nat. Med.
, vol.15
, pp. 808-813
-
-
Gattinoni, L.1
Zhong, X.S.2
Palmer, D.C.3
Ji, Y.4
Hinrichs, C.S.5
Yu, Z.6
Wrzesinski, C.7
Boni, A.8
Cassard, L.9
Garvin, L.M.10
-
70
-
-
79960403269
-
2011. Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor
-
Moon, E., C. Carpenito, J. Sun, L. Wang, V. Kapoor, J. Predina, D. Powell, Jr., J. Riley, C. H. June, and S. M. Albelda. 2011. 2011. Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor. Clin. Cancer Res. 17: 4719-4730.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 4719-4730
-
-
Moon, E.1
Carpenito, C.2
Sun, J.3
Wang, L.4
Kapoor, V.5
Predina, J.6
Powell, D.7
Riley, J.8
June, C.H.9
Albelda, S.M.10
-
71
-
-
84860521444
-
The next challenge in cancer immunotherapy: Controlling T-cell traffic to the tumor
-
Abastado, J.-P. 2012. The next challenge in cancer immunotherapy: controlling T-cell traffic to the tumor. Cancer Res. 72: 2159-2161.
-
(2012)
Cancer Res.
, vol.72
, pp. 2159-2161
-
-
Abastado, J.-P.1
-
72
-
-
0025246123
-
Radiosensitive barrier to T-cell-mediated adoptive immunotherapy of established tumors
-
Awwad, M., and R. J. North. 1990. Radiosensitive barrier to T-cell-mediated adoptive immunotherapy of established tumors. Cancer Res. 50: 2228-2233.
-
(1990)
Cancer Res.
, vol.50
, pp. 2228-2233
-
-
Awwad, M.1
North, R.J.2
-
73
-
-
0036494443
-
Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication
-
Ganss, R., E. Ryschich, E. Klar, B. Arnold, and G. J. Hämmerling. 2002. Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Res. 62: 1462-1470.
-
(2002)
Cancer Res.
, vol.62
, pp. 1462-1470
-
-
Ganss, R.1
Ryschich, E.2
Klar, E.3
Arnold, B.4
Hämmerling, G.J.5
-
74
-
-
15244358572
-
Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes
-
Pinthus, J. H., T. Waks, V. Malina, K. Kaufman-Francis, A. Harmelin, I. Aizenberg, H. Kanety, J. Ramon, and Z. Eshhar. 2004. Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes. J. Clin. Invest. 114: 1774-1781.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1774-1781
-
-
Pinthus, J.H.1
Waks, T.2
Malina, V.3
Kaufman-Francis, K.4
Harmelin, A.5
Aizenberg, I.6
Kanety, H.7
Ramon, J.8
Eshhar, Z.9
-
75
-
-
84925510797
-
Whole-body irradiation increases the magnitude and persistence of adoptively transferred T cells associated with tumor regression in a mouse model of prostate cancer
-
Ward-Kavanagh, L. K., J. Zhu, T. K. Cooper, and T. D. Schell. 2014. Whole-body irradiation increases the magnitude and persistence of adoptively transferred T cells associated with tumor regression in a mouse model of prostate cancer. Cancer Immunol Res 2: 777-788.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 777-788
-
-
Ward-Kavanagh, L.K.1
Zhu, J.2
Cooper, T.K.3
Schell, T.D.4
-
76
-
-
38049051428
-
Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy
-
Qiao, J., T. Kottke, C. Willmon, F. Galivo, P. Wongthida, R. M. Diaz, J. Thompson, P. Ryno, G. N. Barber, J. Chester, et al. 2008. Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy. Nat. Med. 14: 37-44.
-
(2008)
Nat. Med.
, vol.14
, pp. 37-44
-
-
Qiao, J.1
Kottke, T.2
Willmon, C.3
Galivo, F.4
Wongthida, P.5
Diaz, R.M.6
Thompson, J.7
Ryno, P.8
Barber, G.N.9
Chester, J.10
-
77
-
-
33644783747
-
Adoptive transfer of allogeneic cytotoxic T lymphocytes equipped with a HLA-A2 restricted MART-1 T-cell receptor: A phase i trial in metastatic melanoma
-
Duval, L., H. Schmidt, K. Kaltoft, K. Fode, J. J. Jensen, S. M. Sorensen, M. I. Nishimura, and H. von der Maase. 2006. Adoptive transfer of allogeneic cytotoxic T lymphocytes equipped with a HLA-A2 restricted MART-1 T-cell receptor: a phase I trial in metastatic melanoma. Clin. Cancer Res. 12: 1229-1236.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1229-1236
-
-
Duval, L.1
Schmidt, H.2
Kaltoft, K.3
Fode, K.4
Jensen, J.J.5
Sorensen, S.M.6
Nishimura, M.I.7
Maase Der H.Von8
-
78
-
-
84873050511
-
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors
-
Cieri,N., B. Camisa, F. Cocchiarella, M. Forcato,G. Oliveira, E. Provasi, A. Bondanza, C. Bordignon, J. Peccatori, F. Ciceri, et al. 2013. IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors. Blood 121: 573-584.
-
(2013)
Blood
, vol.121
, pp. 573-584
-
-
Cieri, N.1
Camisa, B.2
Cocchiarella, F.3
Forcato, M.4
Oliveira, G.5
Provasi, E.6
Bondanza, A.7
Bordignon, C.8
Peccatori, J.9
Ciceri, F.10
-
79
-
-
84905996839
-
ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells
-
Guedan, S., X. Chen, A. Madar, C. Carpenito, S. E. McGettigan, M. J. Frigault, J. Lee, A. D. Posey, Jr., J. Scholler, N. Scholler, et al. 2014. ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells. Blood 124: 1070-1080.
-
(2014)
Blood
, vol.124
, pp. 1070-1080
-
-
Guedan, S.1
Chen, X.2
Madar, A.3
Carpenito, C.4
McGettigan, S.E.5
Frigault, M.J.6
Lee, J.7
Posey, A.D.8
Scholler, J.9
Scholler, N.10
-
80
-
-
70149106667
-
Type 17 CD8+ T cells display enhanced antitumor immunity
-
Hinrichs, C. S., A. Kaiser, C. M. Paulos, L. Cassard, L. Sanchez-Perez, B. Heemskerk, C. Wrzesinski, Z. A. Borman, P. Muranski, and N. P. Restifo. 2009. Type 17 CD8+ T cells display enhanced antitumor immunity. Blood 114: 596-599.
-
(2009)
Blood
, vol.114
, pp. 596-599
-
-
Hinrichs, C.S.1
Kaiser, A.2
Paulos, C.M.3
Cassard, L.4
Sanchez-Perez, L.5
Heemskerk, B.6
Wrzesinski, C.7
Borman, Z.A.8
Muranski, P.9
Restifo, N.P.10
-
81
-
-
33646440024
-
Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
-
Lamers, C. H., S. Sleijfer, A. G. Vulto, W. H. Kruit, M. Kliffen, R. Debets, J. W. Gratama, G. Stoter, and E. Oosterwijk. 2006. Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J. Clin. Oncol. 24: e20-e22.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. e20-e22
-
-
Lamers, C.H.1
Sleijfer, S.2
Vulto, A.G.3
Kruit, W.H.4
Kliffen, M.5
Debets, R.6
Gratama, J.W.7
Stoter, G.8
Oosterwijk, E.9
-
82
-
-
78549253550
-
Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor
-
Zhao, Y., E. Moon, C. Carpenito, C. M. Paulos, X. Liu, A. L. Brennan, A. Chew, R. G. Carroll, J. Scholler, B. L. Levine, et al. 2010. Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor. Cancer Res. 70: 9053-9061.
-
(2010)
Cancer Res.
, vol.70
, pp. 9053-9061
-
-
Zhao, Y.1
Moon, E.2
Carpenito, C.3
Paulos, C.M.4
Liu, X.5
Brennan, A.L.6
Chew, A.7
Carroll, R.G.8
Scholler, J.9
Levine, B.L.10
-
83
-
-
84996572349
-
Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies
-
Beatty, G. L., A. R. Haas, M. V. Maus, D. A. Torigian, M. C. Soulen, G. Plesa, A. Chew, Y. Zhao, B. L. Levine, S. M. Albelda, et al. 2014. Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies. Cancer Immunol Res 2: 112-120.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 112-120
-
-
Beatty, G.L.1
Haas, A.R.2
Maus, M.V.3
Torigian, D.A.4
Soulen, M.C.5
Plesa, G.6
Chew, A.7
Zhao, Y.8
Levine, B.L.9
Albelda, S.M.10
-
84
-
-
80455162464
-
Inducible apoptosis as a safety switch for adoptive cell therapy
-
Di Stasi, A., S. K. Tey, G. Dotti, Y. Fujita, A. Kennedy-Nasser, C. Martinez, K. Straathof, E. Liu, A. G. Durett, B. Grilley, et al. 2011. Inducible apoptosis as a safety switch for adoptive cell therapy. N. Engl. J. Med. 365: 1673-1683.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1673-1683
-
-
Di Stasi, A.1
Tey, S.K.2
Dotti, G.3
Fujita, Y.4
Kennedy-Nasser, A.5
Martinez, C.6
Straathof, K.7
Liu, E.8
Durett, A.G.9
Grilley, B.10
-
85
-
-
84918540338
-
Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol
-
Wiek, C., E. M. Schmidt, K. Roellecke, M. Freund, M. Nakano, E. J. Kelly, W. Kaisers, V. Yarov-Yarovoy, C. M. Kramm, A. E. Rettie, and H. Hanenberg. 2015. Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol. Biochem. J. 465: 103-114.
-
(2015)
Biochem. J.
, vol.465
, pp. 103-114
-
-
Wiek, C.1
Schmidt, E.M.2
Roellecke, K.3
Freund, M.4
Nakano, M.5
Kelly, E.J.6
Kaisers, W.7
Yarov-Yarovoy, V.8
Kramm, C.M.9
Rettie, A.E.10
Hanenberg, H.11
-
86
-
-
84895487305
-
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
-
Tebas, P., D. Stein, W. W. Tang, I. Frank, S. Q. Wang, G. Lee, S. K. Spratt, R. T. Surosky, M. A. Giedlin, G. Nichol, et al. 2014. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N. Engl. J. Med. 370: 901-910.
-
(2014)
N. Engl. J. Med.
, vol.370
, pp. 901-910
-
-
Tebas, P.1
Stein, D.2
Tang, W.W.3
Frank, I.4
Wang, S.Q.5
Lee, G.6
Spratt, S.K.7
Surosky, R.T.8
Giedlin, M.A.9
Nichol, G.10
-
87
-
-
84886849781
-
Toward eliminating HLA class i expression to generate universal cells from allogeneic donors
-
Torikai, H., A. Reik, F. Soldner, E. H. Warren, C. Yuen, Y. Zhou, D. L. Crossland,H.Huls,N. Littman, Z. Zhang, et al. 2013. Toward eliminating HLA class I expression to generate universal cells from allogeneic donors. Blood 122: 1341-1349.
-
(2013)
Blood
, vol.122
, pp. 1341-1349
-
-
Torikai, H.1
Reik, A.2
Soldner, F.3
Warren, E.H.4
Yuen, C.5
Zhou, Y.6
Crossland, D.L.7
Huls, H.8
Littman, N.9
Zhang, Z.10
-
88
-
-
84861224393
-
Tumor PD-L1 co-stimulates primary human CD8+ cytotoxic T cells modified to express a PD1:CD28 chimeric receptor
-
Prosser, M. E., C. E. Brown, A. F. Shami, S. J. Forman, and M. C. Jensen. 2012. Tumor PD-L1 co-stimulates primary human CD8+ cytotoxic T cells modified to express a PD1:CD28 chimeric receptor. Mol. Immunol. 51: 263-272.
-
(2012)
Mol. Immunol.
, vol.51
, pp. 263-272
-
-
Prosser, M.E.1
Brown, C.E.2
Shami, A.F.3
Forman, S.J.4
Jensen, M.C.5
|