Epigenetic remodeling in B-cell acute lymphoblastic leukemia occurs in two tracks and employs embryonic stem cell-like signatures

Nucleic Acids Research

Volumn 43, Issue 5, 2015, Pages 2590-2602

  Lee, Seung Tae ^a,b   Muench, Marcus O ^a,c   Fomin, Marina E ^c   Xiao, Jianqiao ^a   Zhou, Mi ^a   De Smith, Adam ^a   Martín Subero, José I ^d   Heath, Simon ^e   Houseman, E Andres ^f   Roy, Ritu ^c   Wrensch, Margaret ^a   Wiencke, John ^a   Metayer, Catherine ^g   Wiemels, Joseph L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF BARCELONA   (Spain)

^e Parc Científic de Barcelona   (Spain)

^f OREGON STATE UNIVERSITY   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; MYC PROTEIN; POLYCOMB GROUP PROTEIN; PROTEIN P53; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CTBP2; TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SUZ12; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; CTBP2 PROTEIN, HUMAN; HISTONE; LYSINE; NERVE PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; SUZ12 PROTEIN, HUMAN;

ACUTE LYMPHOBLASTIC LEUKEMIA; AREA UNDER THE CURVE; ARTICLE; B CELL ACUTE LYMPHOBLASTIC LEUKEMIA; BINDING SITE; CELL CYCLE REGULATION; CELL FATE; CHILD; CONTROLLED STUDY; CPG ISLAND; CYTOGENETICS; DE NOVO METHYLATION; DEMETHYLATION; DIFFERENTIALLY METHYLATED REGION; DNA METHYLOME; EMBRYONIC STEM CELL; EPIGENETIC REMODELING; EPIGENETICS; GENE EXPRESSION PROFILING; GENE REPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; LAMINA ASSOCIATED DOMAIN; MAJOR CLINICAL STUDY; METHYLATION; MICROARRAY ANALYSIS; MISMATCH REPAIR; NUCLEIC ACID STRUCTURE, METABOLISM AND FUNCTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; RECEIVER OPERATING CHARACTERISTIC; SEQUENCE ALIGNMENT; WHOLE GENOME BISULFITE SEQUENCING; B LYMPHOCYTE; DNA METHYLATION; DNA MICROARRAY; GENETICS; METABOLISM; PATHOLOGY; PRE B LYMPHOCYTE; PROCEDURES; SIGNAL TRANSDUCTION;

ALCOHOL OXIDOREDUCTASES; B-LYMPHOCYTES; CHILD; CPG ISLANDS; DNA METHYLATION; EMBRYONIC STEM CELLS; EPIGENOMICS; GENE EXPRESSION PROFILING; HISTONES; HUMANS; LYSINE; METHYLATION; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYCOMB REPRESSIVE COMPLEX 2; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PRECURSOR CELLS, B-LYMPHOID; SIGNAL TRANSDUCTION;

EID: 84937598767     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv103     Document Type: Article

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