Baicalein attenuates inflammatory responses by suppressing TLR4 mediated NF-κB and MAPK signaling pathways in LPS-induced mastitis in mice

International Immunopharmacology

Volumn 28, Issue 1, 2015, Pages 470-476

  He, Xuexiu ^a   Wei, Zhengkai ^a   Zhou, Ershun ^a   Chen, Libin ^a   Kou, Jinhua ^a   Wang, Jingjing ^a   Yang, Zhengtao ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Baicalein; Lipopolysaccharide; MAPKs; Mastitis; NF B; TLR4

Indexed keywords

BAICALEIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; I KAPPA B ALPHA; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; FLAVANONE DERIVATIVE; IL1B PROTEIN, MOUSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; PEROXIDASE; TLR4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; GEL MOBILITY SHIFT ASSAY; MALE; MAMMARY GLAND; MASTITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PATHOLOGY; UDDER;

ANIMALS; ANTI-INFLAMMATORY AGENTS; FEMALE; FLAVANONES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MALE; MAMMARY GLANDS, ANIMAL; MAP KINASE SIGNALING SYSTEM; MASTITIS; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PEROXIDASE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84937577013     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2015.07.012     Document Type: Review

References (31)

1. K.R. Petrovski, M. Trajcev, and G. Buneski A review of the factors affecting the costs of bovine mastitis J. S. Afr. Vet. Assoc. 77 2006 52 60
2. M. Geiszt, J. Witta, J. Baffi, K. Lekstrom, and T.L. Leto Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense FASEB J. 17 2003 1502 1504
3. C. Viguier, S. Arora, N. Gilmartin, K. Welbeck, and R. O'Kennedy Mastitis detection: current trends and future perspectives Trends Biotechnol. 27 2009 486 493
4. B.E. Gillespie, H. Moorehead, P. Lunn, H.H. Dowlen, D.L. Johnson, K.C. Lamar, and et al. Efficacy of extended pirlimycin hydrochloride therapy for treatment of environmental Streptococcus spp. and Staphylococcus aureus intramammary infections in lactating dairy cows Vet. Ther. 3 2002 373 380
5. S. Schmitz, M.W. Pfaffl, H.H.D. Meyer, and R.M. Bruckmaier Short-term changes of mRNA expression of various inflammatory factors and milk proteins in mammary tissue during LPS-induced mastitis Domest. Anim. Endocrinol. 26 2004 111 126
6. S. Elazar, E. Gonen, A. Livneh-Kol, I. Rosenshine, and N.Y. Shpigel Essential role of neutrophils but not mammary alveolar macrophages in a murine model of acute Escherichia coli mastitis Vet. Res. 41 2010
7. S. Notebaert, and E. Meyer Mouse models to study the pathogenesis and control of bovine mastitis. A review Vet. Q. 28 2006 2 13
8. S. De Schepper, A. De Ketelaere, D.D. Bannerman, M.J. Paape, L. Peelman, and C. Burvenich The toll-like receptor-4 (TLR-4) pathway and its possible role in the pathogenesis of Escherichia coli mastitis in dairy cattle Vet. Res. 39 2008
9. P.A. Baeuerle, and V.R. Baichwal NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules Adv. Immunol. 65 1997 111 137
10. S. Bhattarai, R.G. Alany, C.R. Bunt, H. Abdelkader, and M.J. Rathbone Design and characterisation of a polyethylene oxide matrix with the potential use as a teat insert for prevention/treatment of bovine mastitis AAPS J. 17 2015 167 174
11. J. Wu, H. Suzuki, A.A. Akhand, Y.W. Zhou, K. Hossain, and I. Nakashima Modes of activation of mitogen-activated protein kinases and their roles in cepharanthine-induced apoptosis in human leukemia cells Cell. Signal. 14 2002 509 515
12. J. Zheng, A.D. Watson, and D.E. Kerr Genome-wide expression analysis of lipopolysaccharide-induced mastitis in a mouse model Infect. Immun. 74 2006 1907 1915
13. Y. Fu, Z. Wei, E. Zhou, N. Zhang, and Z. Yang Cyanidin-3-O-beta-glucoside inhibits lipopolysaccharide-induced inflammatory response in mouse mastitis model J. Lipid Res. 55 2014 1111 1119
14. D.E. Morin, G.C. Petersen, H.L. Whitmore, L.L. Hungerford, and R.A. Hinton Economic analysis of a mastitis monitoring and control program in four dairy herds J. Am. Vet. Med. Assoc. 202 1993 540 548
15. A. Bradley Bovine mastitis: an evolving disease Vet. J. 164 2002 116 128
16. J.E. Krawisz, P. Sharon, and W.F. Stenson Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models Gastroenterology 87 1984 1344 1350
17. J.W. Lee, D.D. Bannerman, M.J. Paape, M.K. Huang, and X. Zhao Characterization of cytokine expression in milk somatic cells during intramammary infections with Escherichia coli or Staphylococcus aureus by real-time PCR Vet. Res. 37 2006 219 229
18. N. Boudjellab, H.S. Chan-Tang, and X. Zhao Bovine interleukin-1 expression by cultured mammary epithelial cells (MAC-T) and its involvement in the release of MAC-T derived interleukin-8 Comp. Biochem. Physiol. A Mol. Integr. Physiol. 127 2000 191 199
19. P. Rainard, and C. Riollet Innate immunity of the bovine mammary gland Vet. Res. 37 2006 369 400
20. M.K. Connolly, A.S. Bedrosian, J.M.S. Clair, A.P. Mitchell, J. Ibrahim, A. Stroud, and et al. In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha J. Clin. Investig. 119 2009 3213 3225
21. J.W. Christman, R.T. Sadikot, and T.S. Blackwell The role of nuclear factor-kappa B in pulmonary diseases Chest 117 2000 1482 1487
22. S. Vallabhapurapu, and M. Karin Regulation and function of NF-kappaB transcription factors in the immune system Annu. Rev. Immunol. 27 2009 693 733
23. A. Rai, S. Kapoor, S. Singh, B.P. Chatterji, and D. Panda Transcription factor NF-kappaB associates with microtubules and stimulates apoptosis in response to suppression of microtubule dynamics in MCF-7 cells Biochem. Pharmacol. 93 2015 277 289
24. K. Heyninck, M. Lahtela-Kakkonen, P. Van der Veken, G. Haegeman, and W. Vanden Berghe Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKbeta Biochem. Pharmacol. 91 2014 501 509
25. S.D. Kim, Y.J. Lee, J.S. Baik, J.Y. Han, C.G. Lee, K. Heo, and et al. Baicalein inhibits agonist- and tumor cell-induced platelet aggregation while suppressing pulmonary tumor metastasis via cAMP-mediated VASP phosphorylation along with impaired MAPKs and PI3K-Akt activation Biochem. Pharmacol. 92 2014 251 265
26. T. Shuto, K. Kato, Y. Mori, S. Viriyakosol, M. Oba, T. Furuta, and et al. Membrane-anchored CD14 is required for LPS-induced TLR4 endocytosis in TLR4/MD-2/CD14 overexpressing CHO cells Biochem. Biophys. Res. Commun. 338 2005 1402 1409
27. Y.C. Lu, W.C. Yeh, and P.S. Ohashi LPS/TLR4 signal transduction pathway Cytokine 42 2008 145 151
28. X.J. Gao, M.Y. Guo, Z.C. Zhang, T.C. Wang, Y.G. Cao, and N.S. Zhang Bergenin plays an anti-inflammatory role via the modulation of MAPK and NF-kappaB signaling pathways in a mouse model of LPS-induced mastitis Inflammation 38 2015 1142 1150
29. D.P. Li, Y.H. Fu, W. Zhang, G.L. Su, B. Liu, M.Y. Guo, and et al. Salidroside attenuates inflammatory responses by suppressing nuclear factor-kappa B and mitogen activated protein kinases activation in lipopolysaccharide-induced mastitis in mice Inflamm. Res. 62 2013 9 15
30. Y. Fu, R. Gao, Y. Cao, M. Guo, Z. Wei, E. Zhou, and et al. Curcumin attenuates inflammatory responses by suppressing TLR4-mediated NF-kappaB signaling pathway in lipopolysaccharide-induced mastitis in mice Int. Immunopharmacol. 20 2014 54 58
31. M.Y. Guo, Y.G. Cao, T.C. Wang, X.J. Song, Z.C. Liu, E.S. Zhou, and et al. Baicalin inhibits Staphylococcus aureus-induced apoptosis by regulating TLR2 and TLR2-related apoptotic factors in the mouse mammary glands Eur. J. Pharmacol. 723 2014 481 488