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Volumn 72, Issue 7, 2015, Pages 756-763

Long-term therapy with interleukin 6 receptor blockade in highly active neuromyelitis optica spectrum disorder

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMITRIPTYLINE; AQUAPORIN 4 ANTIBODY; AZATHIOPRINE; C REACTIVE PROTEIN; CARBAMAZEPINE; CORTICOSTEROID; GABAPENTIN; INTERLEUKIN 6 RECEPTOR; METHYLPREDNISOLONE; NALOXONE; NALOXONE PLUS OXYCODONE; PARACETAMOL; PREDNISOLONE SODIUM SUCCINATE; PREGABALIN; TETRAHYDROCANNABINOL; TILIDINE; TOCILIZUMAB; MONOCLONAL ANTIBODY;

EID: 84937558591     PISSN: 21686149     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaneurol.2015.0533     Document Type: Article
Times cited : (193)

References (37)
  • 2
    • 84855864768 scopus 로고    scopus 로고
    • Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients
    • Jarius S, Ruprecht K, Wildemann B, et al. Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients. J Neuroinflammation. 2012;9:14.
    • (2012) J Neuroinflammation , vol.9 , pp. 14
    • Jarius, S.1    Ruprecht, K.2    Wildemann, B.3
  • 3
    • 84895076673 scopus 로고    scopus 로고
    • Update on the diagnosis and treatment of neuromyelitis optica: Recommendations of the Neuromyelitis Optica Study Group (NEMOS)
    • Trebst C, Jarius S, Berthele A, et al Neuromyelitis Optica Study Group (NEMOS). Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS). J Neurol. 2014;261(1):1-16.
    • (2014) J Neurol , vol.261 , Issue.1 , pp. 1-16
    • Trebst, C.1    Jarius, S.2    Berthele, A.3
  • 4
    • 78049510106 scopus 로고    scopus 로고
    • IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum
    • Shimizu J, Hatanaka Y, Hasegawa M, et al. IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum. Neurology. 2010;75(16):1423-1427.
    • (2010) Neurology , vol.75 , Issue.16 , pp. 1423-1427
    • Shimizu, J.1    Hatanaka, Y.2    Hasegawa, M.3
  • 5
    • 84856923074 scopus 로고    scopus 로고
    • Failure of natalizumab to prevent relapses in neuromyelitis optica
    • Kleiter I, Hellwig K, Berthele A, et al Neuromyelitis Optica Study Group. Failure of natalizumab to prevent relapses in neuromyelitis optica. Arch Neurol. 2012;69(2):239-245.
    • (2012) Arch Neurol , vol.69 , Issue.2 , pp. 239-245
    • Kleiter, I.1    Hellwig, K.2    Berthele, A.3
  • 6
    • 84862908479 scopus 로고    scopus 로고
    • Development of extensive brain lesions following fingolimod (FTY720) treatment in a patient with neuromyelitis optica spectrum disorder
    • Min JH, Kim BJ, Lee KH. Development of extensive brain lesions following fingolimod (FTY720) treatment in a patient with neuromyelitis optica spectrum disorder. Mult Scler. 2012;18(1):113-115.
    • (2012) Mult Scler , vol.18 , Issue.1 , pp. 113-115
    • Min, J.H.1    Kim, B.J.2    Lee, K.H.3
  • 7
    • 84906791521 scopus 로고    scopus 로고
    • Long-term efficacy, tolerability and retention rate of azathioprine in 103 aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder patients: A multicentre retrospective observational study from the UK
    • Elsone L, Kitley J, Luppe S, et al. Long-term efficacy, tolerability and retention rate of azathioprine in 103 aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder patients: a multicentre retrospective observational study from the UK. Mult Scler. 2014;20(11):1533-1540.
    • (2014) Mult Scler , vol.20 , Issue.11 , pp. 1533-1540
    • Elsone, L.1    Kitley, J.2    Luppe, S.3
  • 8
    • 84919343736 scopus 로고    scopus 로고
    • Mycophenolate mofetil in the treatment of neuromyelitis optica spectrum disorder
    • Huh SY, Kim SH, Hyun JW, et al. Mycophenolate mofetil in the treatment of neuromyelitis optica spectrum disorder. JAMA Neurol. 2014;71(11):1372-1378.
    • (2014) JAMA Neurol , vol.71 , Issue.11 , pp. 1372-1378
    • Huh, S.Y.1    Kim, S.H.2    Hyun, J.W.3
  • 9
    • 84879895266 scopus 로고    scopus 로고
    • Methotrexate is an alternative to azathioprine in neuromyelitis optica spectrum disorders with aquaporin-4 antibodies
    • Kitley J, Elsone L, George J, et al. Methotrexate is an alternative to azathioprine in neuromyelitis optica spectrum disorders with aquaporin-4 antibodies. J Neurol Neurosurg Psychiatry. 2013;84(8):918-921.
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , Issue.8 , pp. 918-921
    • Kitley, J.1    Elsone, L.2    George, J.3
  • 10
    • 84883820098 scopus 로고    scopus 로고
    • A 5-year follow-up of rituximab treatment in patients with neuromyelitis optica spectrum disorder
    • Kim SH, Huh SY, Lee SJ, Joung A, Kim HJ. A 5-year follow-up of rituximab treatment in patients with neuromyelitis optica spectrum disorder. JAMA Neurol. 2013;70(9):1110-1117.
    • (2013) JAMA Neurol , vol.70 , Issue.9 , pp. 1110-1117
    • Kim, S.H.1    Huh, S.Y.2    Lee, S.J.3    Joung, A.4    Kim, H.J.5
  • 13
    • 23944444890 scopus 로고    scopus 로고
    • IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
    • Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med. 2005;202(4):473-477.
    • (2005) J Exp Med , vol.202 , Issue.4 , pp. 473-477
    • Lennon, V.A.1    Kryzer, T.J.2    Pittock, S.J.3    Verkman, A.S.4    Hinson, S.R.5
  • 14
    • 78650092261 scopus 로고    scopus 로고
    • Cytokine and chemokine profiles in neuromyelitis optica: Significance of interleukin-6
    • Uzawa A, Mori M, Arai K, et al. Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6. Mult Scler. 2010;16(12):1443-1452.
    • (2010) Mult Scler , vol.16 , Issue.12 , pp. 1443-1452
    • Uzawa, A.1    Mori, M.2    Arai, K.3
  • 15
    • 79952762854 scopus 로고    scopus 로고
    • Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
    • Chihara N, Aranami T, Sato W, et al. Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. Proc Natl Acad Sci USA. 2011;108(9):3701-3706.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.9 , pp. 3701-3706
    • Chihara, N.1    Aranami, T.2    Sato, W.3
  • 16
    • 84930667205 scopus 로고    scopus 로고
    • Tocilizumab, a humanized anti-IL-6R antibody, as an emerging therapeutic option for rheumatoid arthritis: Molecular and cellular mechanistic insights
    • published online August 6, 2014
    • Hashizume M, Tan SL, Takano J, et al. Tocilizumab, a humanized anti-IL-6R antibody, as an emerging therapeutic option for rheumatoid arthritis: molecular and cellular mechanistic insights [published online August 6, 2014]. Int Rev Immunol.
    • Int Rev Immunol
    • Hashizume, M.1    Tan, S.L.2    Takano, J.3
  • 17
    • 84874859809 scopus 로고    scopus 로고
    • Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: Implication for cellular immune responses
    • Kieseier BC, Stüve O, Dehmel T, et al. Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: implication for cellular immune responses. JAMA Neurol. 2013;70(3):390-393.
    • (2013) JAMA Neurol , vol.70 , Issue.3 , pp. 390-393
    • Kieseier, B.C.1    Stüve, O.2    Dehmel, T.3
  • 18
    • 84874904135 scopus 로고    scopus 로고
    • Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy
    • Ayzenberg I, Kleiter I, Schröder A, et al. Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy. JAMA Neurol. 2013;70(3):394-397.
    • (2013) JAMA Neurol , vol.70 , Issue.3 , pp. 394-397
    • Ayzenberg, I.1    Kleiter, I.2    Schröder, A.3
  • 19
    • 84880844455 scopus 로고    scopus 로고
    • Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab
    • Araki M, Aranami T, Matsuoka T, Nakamura M, Miyake S, Yamamura T. Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab. Mod Rheumatol. 2013;23(4):827-831.
    • (2013) Mod Rheumatol , vol.23 , Issue.4 , pp. 827-831
    • Araki, M.1    Aranami, T.2    Matsuoka, T.3    Nakamura, M.4    Miyake, S.5    Yamamura, T.6
  • 20
    • 84902096246 scopus 로고    scopus 로고
    • Efficacy of the anti-IL-6 receptor antibody tocilizumab in neuromyelitis optica: A pilot study
    • Araki M, Matsuoka T, Miyamoto K, et al. Efficacy of the anti-IL-6 receptor antibody tocilizumab in neuromyelitis optica: a pilot study. Neurology. 2014;82(15):1302-1306.
    • (2014) Neurology , vol.82 , Issue.15 , pp. 1302-1306
    • Araki, M.1    Matsuoka, T.2    Miyamoto, K.3
  • 21
    • 84898656660 scopus 로고    scopus 로고
    • Treating neuromyelitis optica with the interleukin-6 receptor antagonist tocilizumab
    • bcr2013202939
    • Lauenstein AS, Stettner M, Kieseier BC, Lensch E. Treating neuromyelitis optica with the interleukin-6 receptor antagonist tocilizumab. BMJ Case Rep. 2014:bcr2013202939. doi:10.1136/bcr-2013-202939.
    • (2014) BMJ Case Rep
    • Lauenstein, A.S.1    Stettner, M.2    Kieseier, B.C.3    Lensch, E.4
  • 22
    • 84902094466 scopus 로고    scopus 로고
    • Devic disease: Translational medicine at work
    • Rose-John S, Gold R. Devic disease: translational medicine at work. Neurology. 2014;82(15):1294-1295.
    • (2014) Neurology , vol.82 , Issue.15 , pp. 1294-1295
    • Rose-John, S.1    Gold, R.2
  • 24
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An Expanded Disability Status Scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an Expanded Disability Status Scale (EDSS). Neurology. 1983;33(11):1444-1452.
    • (1983) Neurology , vol.33 , Issue.11 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 25
    • 77649180422 scopus 로고    scopus 로고
    • Standardized method for the detection of antibodies to aquaporin-4 based on a highly sensitive immunofluorescence assay employing recombinant target antigen
    • Jarius S, Probst C, Borowski K, et al. Standardized method for the detection of antibodies to aquaporin-4 based on a highly sensitive immunofluorescence assay employing recombinant target antigen. J Neurol Sci. 2010;291(1-2):52-56.
    • (2010) J Neurol Sci , vol.291 , Issue.1-2 , pp. 52-56
    • Jarius, S.1    Probst, C.2    Borowski, K.3
  • 26
    • 0033402420 scopus 로고    scopus 로고
    • Interleukin-6 expression and regulation in astrocytes
    • Van Wagoner NJ, Benveniste EN. Interleukin-6 expression and regulation in astrocytes. J Neuroimmunol. 1999;100(1-2):124-139.
    • (1999) J Neuroimmunol , vol.100 , Issue.1-2 , pp. 124-139
    • Van Wagoner, N.J.1    Benveniste, E.N.2
  • 27
    • 26444619864 scopus 로고    scopus 로고
    • IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis
    • Kaplin AI, Deshpande DM, Scott E, et al. IL-6 induces regionally selective spinal cord injury in patients with the neuroinflammatory disorder transverse myelitis. J Clin Invest. 2005;115(10):2731-2741.
    • (2005) J Clin Invest , vol.115 , Issue.10 , pp. 2731-2741
    • Kaplin, A.I.1    Deshpande, D.M.2    Scott, E.3
  • 28
    • 84355166544 scopus 로고    scopus 로고
    • Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms
    • Zhang H, Bennett JL, Verkman AS. Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms. Ann Neurol. 2011;70(6):943-954.
    • (2011) Ann Neurol , vol.70 , Issue.6 , pp. 943-954
    • Zhang, H.1    Bennett, J.L.2    Verkman, A.S.3
  • 29
    • 72949093353 scopus 로고    scopus 로고
    • Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica
    • Bennett JL, Lam C, Kalluri SR, et al. Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica. Ann Neurol. 2009;66(5):617-629.
    • (2009) Ann Neurol , vol.66 , Issue.5 , pp. 617-629
    • Bennett, J.L.1    Lam, C.2    Kalluri, S.R.3
  • 30
    • 55749088210 scopus 로고    scopus 로고
    • Antibody to aquaporin-4 in the long-term course of neuromyelitis optica
    • Jarius S, Aboul-Enein F, Waters P, et al. Antibody to aquaporin-4 in the long-term course of neuromyelitis optica. Brain. 2008;131(pt 11):3072-3080.
    • (2008) Brain , vol.131 , pp. 3072-3080
    • Jarius, S.1    Aboul-Enein, F.2    Waters, P.3
  • 31
    • 80055085027 scopus 로고    scopus 로고
    • Pain in neuromyelitis optica and its effect on quality of life: A cross-sectional study
    • Kanamori Y, Nakashima I, Takai Y, et al. Pain in neuromyelitis optica and its effect on quality of life: a cross-sectional study. Neurology. 2011;77(7):652-658.
    • (2011) Neurology , vol.77 , Issue.7 , pp. 652-658
    • Kanamori, Y.1    Nakashima, I.2    Takai, Y.3
  • 33
    • 84908096180 scopus 로고    scopus 로고
    • Pain in neuromyelitis optica: Prevalence, pathogenesis and therapy
    • Bradl M, Kanamori Y, Nakashima I, et al. Pain in neuromyelitis optica: prevalence, pathogenesis and therapy. Nat Rev Neurol. 2014;10(9):529-536.
    • (2014) Nat Rev Neurol , vol.10 , Issue.9 , pp. 529-536
    • Bradl, M.1    Kanamori, Y.2    Nakashima, I.3
  • 34
    • 84890759137 scopus 로고    scopus 로고
    • Cytokines and chemokines in neuromyelitis optica: Pathogenetic and therapeutic implications
    • Uzawa A, Mori M, Kuwabara S. Cytokines and chemokines in neuromyelitis optica: pathogenetic and therapeutic implications. Brain Pathol.2014;24(1):67-73.
    • (2014) Brain Pathol , vol.24 , Issue.1 , pp. 67-73
    • Uzawa, A.1    Mori, M.2    Kuwabara, S.3
  • 35
    • 84868142444 scopus 로고    scopus 로고
    • Efficacy of epidural administration of anti-interleukin-6 receptor antibody onto spinal nerve for treatment of sciatica
    • Ohtori S, Miyagi M, Eguchi Y, et al. Efficacy of epidural administration of anti-interleukin-6 receptor antibody onto spinal nerve for treatment of sciatica. Eur Spine J. 2012;21(10):2079-2084.
    • (2012) Eur Spine J , vol.21 , Issue.10 , pp. 2079-2084
    • Ohtori, S.1    Miyagi, M.2    Eguchi, Y.3
  • 36
    • 40749114497 scopus 로고    scopus 로고
    • Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): A double-blind, placebo-controlled, randomised trial
    • Smolen JS, Beaulieu A, Rubbert-Roth A, et al OPTION Investigators. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet. 2008;371(9617):987-997.
    • (2008) Lancet , vol.371 , Issue.9617 , pp. 987-997
    • Smolen, J.S.1    Beaulieu, A.2    Rubbert-Roth, A.3
  • 37
    • 84905586060 scopus 로고    scopus 로고
    • Potential patient benefit of a subcutaneous formulation of tocilizumab for the treatment of rheumatoid arthritis: A critical review
    • Besada E. Potential patient benefit of a subcutaneous formulation of tocilizumab for the treatment of rheumatoid arthritis: a critical review. Patient Prefer Adherence. 2014;8:1051-1059.
    • (2014) Patient Prefer Adherence , vol.8 , pp. 1051-1059
    • Besada, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.