메뉴 건너뛰기




Volumn 42, Issue 7, 2015, Pages 647-657

Systemic antibiotics in the treatment of aggressive periodontitis. A systematic review and a Bayesian Network meta-analysis

Author keywords

aggressive periodontitis; amoxicillin; anti infective agents; metronidazole; root planing; systematic review

Indexed keywords

AMOXICILLIN; ANTIINFECTIVE AGENT; METRONIDAZOLE;

EID: 84937556905     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/jcpe.12427     Document Type: Review
Times cited : (91)

References (38)
  • 2
    • 84856615454 scopus 로고    scopus 로고
    • Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: A randomized, placebo-controlled trial
    • Aimetti, M., Romano, F., Guzzi, N., and, Carnevale, G., (2012) Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive periodontitis: a randomized, placebo-controlled trial. Journal of Clinical Periodontology 39, 284-294.
    • (2012) Journal of Clinical Periodontology , vol.39 , pp. 284-294
    • Aimetti, M.1    Romano, F.2    Guzzi, N.3    Carnevale, G.4
  • 3
    • 49849106679 scopus 로고    scopus 로고
    • Systemic administration of doxycycline versus metronidazole plus amoxicillin in the treatment of localized aggressive periodontitis: A clinical and microbiologic study
    • Akincibay, H., Orsal, S. O., Sengün, D., and, Tözüm, T. F., (2008) Systemic administration of doxycycline versus metronidazole plus amoxicillin in the treatment of localized aggressive periodontitis: a clinical and microbiologic study. Quintessence International 39, 33-39.
    • (2008) Quintessence International , vol.39 , pp. 33-39
    • Akincibay, H.1    Orsal, S.O.2    Sengün, D.3    Tözüm, T.F.4
  • 4
    • 0033288546 scopus 로고    scopus 로고
    • Development of a classification system for periodontal diseases and conditions
    • Armitage, G. C., (1999) Development of a classification system for periodontal diseases and conditions. Annals of Periodontology 4, 1-6.
    • (1999) Annals of Periodontology , vol.4 , pp. 1-6
    • Armitage, G.C.1
  • 5
    • 1542507065 scopus 로고    scopus 로고
    • Periodontal diagnoses and classification of periodontal diseases
    • Armitage, G. C., (2004) Periodontal diagnoses and classification of periodontal diseases. Periodontology 2000 34, 9-21.
    • (2004) Periodontology 2000 , vol.34 , pp. 9-21
    • Armitage, G.C.1
  • 6
    • 84864943507 scopus 로고    scopus 로고
    • The combination of amoxicillin and metronidazole improves clinical and microbiologic results of one-stage, full-mouth, ultrasonic debridement in aggressive periodontitis treatment
    • Casarin, R. C., Peloso Ribeiro, E. D., Sallum, E. A., Nociti, F. H. Jr, Gonçalves, R. B., and, Casati, M. Z., (2012) The combination of amoxicillin and metronidazole improves clinical and microbiologic results of one-stage, full-mouth, ultrasonic debridement in aggressive periodontitis treatment. Journal of Periodontology 83, 988-998.
    • (2012) Journal of Periodontology , vol.83 , pp. 988-998
    • Casarin, R.C.1    Peloso Ribeiro, E.D.2    Sallum, E.A.3    Nociti, Jr.F.H.4    Gonçalves, R.B.5    Casati, M.Z.6
  • 7
    • 78649291964 scopus 로고    scopus 로고
    • Evidence-based periodontal plastic surgery: An assessment of quality of systematic reviews in the treatment of recession-type defects
    • Chambrone, L., Faggion, C. M., Pannuti, C. M., and, Chambrone, L. A., (2010) Evidence-based periodontal plastic surgery: an assessment of quality of systematic reviews in the treatment of recession-type defects. Journal of Clinical Periodontology 37, 1110-1118.
    • (2010) Journal of Clinical Periodontology , vol.37 , pp. 1110-1118
    • Chambrone, L.1    Faggion, C.M.2    Pannuti, C.M.3    Chambrone, L.A.4
  • 8
    • 84859487919 scopus 로고    scopus 로고
    • Evidence-based periodontal plastic surgery. II. An individual data meta-analysis for evaluating factors in achieving complete root coverage
    • Chambrone, L., Pannuti, C. M., Tu, Y. K., and, Chambrone, L. A., (2012) Evidence-based periodontal plastic surgery. II. An individual data meta-analysis for evaluating factors in achieving complete root coverage. Journal of Periodontology 83, 477-490.
    • (2012) Journal of Periodontology , vol.83 , pp. 477-490
    • Chambrone, L.1    Pannuti, C.M.2    Tu, Y.K.3    Chambrone, L.A.4
  • 9
    • 84877578488 scopus 로고    scopus 로고
    • Effects of smoking cessation on the outcomes of non-surgical periodontal therapy: A systematic review and individual patient data meta-analysis
    • Chambrone, L., Preshaw, P. M., Rosa, E. F., Heasman, P. A., Romito, G. A., Pannuti, C. M., and, Tu, Y. K., (2013) Effects of smoking cessation on the outcomes of non-surgical periodontal therapy: a systematic review and individual patient data meta-analysis. Journal of Clinical Periodontology 40, 607-615.
    • (2013) Journal of Clinical Periodontology , vol.40 , pp. 607-615
    • Chambrone, L.1    Preshaw, P.M.2    Rosa, E.F.3    Heasman, P.A.4    Romito, G.A.5    Pannuti, C.M.6    Tu, Y.K.7
  • 10
    • 84867232119 scopus 로고    scopus 로고
    • Effect of azithromycin, as an adjunct to nonsurgical periodontal treatment, on microbiological parameters and gingival crevicular fluid biomarkers in generalized aggressive periodontitis
    • Emingil, G., Han, B., Ozdemir, G., Tervahartiala, T., Vural, C., Atilla, G., Baylas, H., and, Sorsa, T., (2012) Effect of azithromycin, as an adjunct to nonsurgical periodontal treatment, on microbiological parameters and gingival crevicular fluid biomarkers in generalized aggressive periodontitis. Journal of Periodontal Research 47, 729-739.
    • (2012) Journal of Periodontal Research , vol.47 , pp. 729-739
    • Emingil, G.1    Han, B.2    Ozdemir, G.3    Tervahartiala, T.4    Vural, C.5    Atilla, G.6    Baylas, H.7    Sorsa, T.8
  • 11
    • 84881232023 scopus 로고    scopus 로고
    • Network meta-analysis for evaluating interventions in implant dentistry: The case of peri-implantitis treatment
    • Faggion, C. M. Jr, Chambrone, L., Listl, S., and, Tu, Y. K., (2013) Network meta-analysis for evaluating interventions in implant dentistry: the case of peri-implantitis treatment. Clinical Implant Dentistry and Related Research 15, 576-588.
    • (2013) Clinical Implant Dentistry and Related Research , vol.15 , pp. 576-588
    • Faggion, Jr.C.M.1    Chambrone, L.2    Listl, S.3    Tu, Y.K.4
  • 12
    • 0026776749 scopus 로고
    • Variance imputation for overviews of clinical trials with continuous response
    • Follmann, D., Elliott, P., Suh, I., and, Cutler, J., (1992) Variance imputation for overviews of clinical trials with continuous response. Journal of Clinical Epidemiology 45, 769-773.
    • (1992) Journal of Clinical Epidemiology , vol.45 , pp. 769-773
    • Follmann, D.1    Elliott, P.2    Suh, I.3    Cutler, J.4
  • 13
    • 25844497516 scopus 로고    scopus 로고
    • Adjunctive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: A randomized placebo-controlled clinical trial
    • Guerrero, A., Griffiths, G. S., Nibali, L., Suvan, J., Moles, D. R., Laurell, L., and, Tonetti, M. S., (2005) Adjunctive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: a randomized placebo-controlled clinical trial. Journal of Clinical Periodontology 32, 1096-1107.
    • (2005) Journal of Clinical Periodontology , vol.32 , pp. 1096-1107
    • Guerrero, A.1    Griffiths, G.S.2    Nibali, L.3    Suvan, J.4    Moles, D.R.5    Laurell, L.6    Tonetti, M.S.7
  • 15
    • 1442327411 scopus 로고    scopus 로고
    • Systemic anti-infective periodontal therapy. A systematic review
    • Haffajee, A. D., Socransky, S. S., and, Gunsolley, J. C., (2003) Systemic anti-infective periodontal therapy. A systematic review. Annals of Periodontology 8, 115-181.
    • (2003) Annals of Periodontology , vol.8 , pp. 115-181
    • Haffajee, A.D.1    Socransky, S.S.2    Gunsolley, J.C.3
  • 16
    • 79952216378 scopus 로고    scopus 로고
    • Impact of systemic antimicrobials combined with anti-infective mechanical debridement on the microbiota of generalized aggressive periodontitis: A 6-month RCT
    • Heller, D., Varela, V. M., Silva-Senem, M. X., Torres, M. C., Feres-Filho, E. J., and, Colombo, A. P., (2011) Impact of systemic antimicrobials combined with anti-infective mechanical debridement on the microbiota of generalized aggressive periodontitis: a 6-month RCT. Journal of Clinical Periodontology 38, 355-364.
    • (2011) Journal of Clinical Periodontology , vol.38 , pp. 355-364
    • Heller, D.1    Varela, V.M.2    Silva-Senem, M.X.3    Torres, M.C.4    Feres-Filho, E.J.5    Colombo, A.P.6
  • 17
    • 0037928810 scopus 로고    scopus 로고
    • A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients
    • discussion 160-2
    • Herrera, D., Sanz, M., Jepsen, S., Needleman, I., and, Roldán, S., (2002) A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients. Journal of Clinical Periodontology 29 (Suppl 3), 136-159; discussion 160-2.
    • (2002) Journal of Clinical Periodontology , vol.29 , pp. 136-159
    • Herrera, D.1    Sanz, M.2    Jepsen, S.3    Needleman, I.4    Roldán, S.5
  • 19
    • 84945467095 scopus 로고    scopus 로고
    • Non-surgical periodontal therapy with systemic antibiotics in patients with untreated aggressive periodontitis: A systematic review and meta-analysis
    • Keestra, J. A., Grosjean, I., Coucke, W., Quirynen, M., and, Teughels, W., (2014) Non-surgical periodontal therapy with systemic antibiotics in patients with untreated aggressive periodontitis: a systematic review and meta-analysis. Journal of Periodontal Research doi: 10.1111/jre.12252. [Epub ahead of print].
    • (2014) Journal of Periodontal Research
    • Keestra, J.A.1    Grosjean, I.2    Coucke, W.3    Quirynen, M.4    Teughels, W.5
  • 20
    • 84921528047 scopus 로고    scopus 로고
    • Non-surgical periodontal therapy with systemic antibiotics in patients with untreated chronic periodontitis: A systematic review and meta-analysis
    • Keestra, J. A., Grosjean, I., Coucke, W., Quirynen, M., and, Teughels, W., (2015) Non-surgical periodontal therapy with systemic antibiotics in patients with untreated chronic periodontitis: a systematic review and meta-analysis. Journal of Periodontal Research 50, 294-314.
    • (2015) Journal of Periodontal Research , vol.50 , pp. 294-314
    • Keestra, J.A.1    Grosjean, I.2    Coucke, W.3    Quirynen, M.4    Teughels, W.5
  • 21
    • 5044221416 scopus 로고    scopus 로고
    • Combination of direct and indirect evidence in mixed treatment comparisons
    • Lu, G., and, Ades, A. E., (2004) Combination of direct and indirect evidence in mixed treatment comparisons. Statistics in Medicine 23, 3105-3124.
    • (2004) Statistics in Medicine , vol.23 , pp. 3105-3124
    • Lu, G.1    Ades, A.E.2
  • 22
    • 77949769804 scopus 로고    scopus 로고
    • Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis
    • Mestnik, M. J., Feres, M., Figueiredo, L. C., Duarte, P. M., Lira, E. A., and, Faveri, M., (2010) Short-term benefits of the adjunctive use of metronidazole plus amoxicillin in the microbial profile and in the clinical parameters of subjects with generalized aggressive periodontitis. Journal of Clinical Periodontology 37, 353-365.
    • (2010) Journal of Clinical Periodontology , vol.37 , pp. 353-365
    • Mestnik, M.J.1    Feres, M.2    Figueiredo, L.C.3    Duarte, P.M.4    Lira, E.A.5    Faveri, M.6
  • 23
    • 84866108516 scopus 로고    scopus 로고
    • The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: A 1-year double-blinded, placebo-controlled, randomized clinical trial
    • Mestnik, M. J., Feres, M., Figueiredo, L. C., Soares, G., Teles, R. P., Fermiano, D., Duarte, P. M., and, Faveri, M., (2012) The effects of adjunctive metronidazole plus amoxicillin in the treatment of generalized aggressive periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial. Journal of Clinical Periodontology 39, 955-961.
    • (2012) Journal of Clinical Periodontology , vol.39 , pp. 955-961
    • Mestnik, M.J.1    Feres, M.2    Figueiredo, L.C.3    Soares, G.4    Teles, R.P.5    Fermiano, D.6    Duarte, P.M.7    Faveri, M.8
  • 24
    • 84925548115 scopus 로고    scopus 로고
    • Methods of systematic reviews and meta-analysis preferred reporting items for systematic reviews and meta-analyses: The PRISMA Statement
    • The PRISMA Group
    • Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., and The PRISMA Group (2009) Methods of systematic reviews and meta-analysis preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement. Journal of Clinical Epidemiology 62, 1006-1101.
    • (2009) Journal of Clinical Epidemiology , vol.62 , pp. 1006-1101
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 25
    • 0027407948 scopus 로고
    • Metronidazole in the treatment of localized juvenile periodontitis
    • Saxén, L., and, Asikainen, S., (1993) Metronidazole in the treatment of localized juvenile periodontitis. Journal of Clinical Periodontology 20, 166-171.
    • (1993) Journal of Clinical Periodontology , vol.20 , pp. 166-171
    • Saxén, L.1    Asikainen, S.2
  • 26
    • 84867318968 scopus 로고    scopus 로고
    • Effectiveness of systemic amoxicillin/metronidazole as adjunctive therapy to scaling and root planing in the treatment of chronic periodontitis: A systematic review and meta-analysis
    • Sgolastra, F., Gatto, R., Petrucci, A., and, Monaco, A., (2012a) Effectiveness of systemic amoxicillin/metronidazole as adjunctive therapy to scaling and root planing in the treatment of chronic periodontitis: a systematic review and meta-analysis. Journal of Periodontology 83, 1257-1269.
    • (2012) Journal of Periodontology , vol.83 , pp. 1257-1269
    • Sgolastra, F.1    Gatto, R.2    Petrucci, A.3    Monaco, A.4
  • 27
    • 84855798971 scopus 로고    scopus 로고
    • Effectiveness of systemic amoxicillin/metronidazole as an adjunctive therapy to full-mouth scaling and root planing in the treatment of aggressive periodontitis: A systematic review and meta-analysis
    • Sgolastra, F., Petrucci, A., Gatto, R., and, Monaco, A., (2012b) Effectiveness of systemic amoxicillin/metronidazole as an adjunctive therapy to full-mouth scaling and root planing in the treatment of aggressive periodontitis: a systematic review and meta-analysis. Journal of Periodontology 83, 731-743.
    • (2012) Journal of Periodontology , vol.83 , pp. 731-743
    • Sgolastra, F.1    Petrucci, A.2    Gatto, R.3    Monaco, A.4
  • 28
    • 0034983665 scopus 로고    scopus 로고
    • A 2-step non-surgical procedure and systemic antibiotics in the treatment of rapidly progressive periodontitis
    • Sigusch, B., Beier, M., Klinger, G., Pfister, W., and, Glockmann, E., (2001) A 2-step non-surgical procedure and systemic antibiotics in the treatment of rapidly progressive periodontitis. Journal of Periodontology 72, 275-283.
    • (2001) Journal of Periodontology , vol.72 , pp. 275-283
    • Sigusch, B.1    Beier, M.2    Klinger, G.3    Pfister, W.4    Glockmann, E.5
  • 29
    • 84873408325 scopus 로고    scopus 로고
    • Clinical and microbiological effects of systemic antimicrobials combined to an anti-infective mechanical debridement for the management of aggressive periodontitis: A 12-month randomized controlled trial
    • Silva-Senem, M. X., Heller, D., Varela, V. M., Torres, M. C., Feres-Filho, E. J., and, Colombo, A. P., (2013) Clinical and microbiological effects of systemic antimicrobials combined to an anti-infective mechanical debridement for the management of aggressive periodontitis: a 12-month randomized controlled trial. Journal of Clinical Periodontology 40, 242-251.
    • (2013) Journal of Clinical Periodontology , vol.40 , pp. 242-251
    • Silva-Senem, M.X.1    Heller, D.2    Varela, V.M.3    Torres, M.C.4    Feres-Filho, E.J.5    Colombo, A.P.6
  • 30
    • 51149095603 scopus 로고    scopus 로고
    • Use of indirect and mixed treatment comparisons for technology assessment
    • Sutton, A., Ades, A. E., Cooper, N., and, Abrams, K., (2008) Use of indirect and mixed treatment comparisons for technology assessment. Pharmacoeconomics 26, 753-767.
    • (2008) Pharmacoeconomics , vol.26 , pp. 753-767
    • Sutton, A.1    Ades, A.E.2    Cooper, N.3    Abrams, K.4
  • 31
    • 84875878623 scopus 로고    scopus 로고
    • Sample size and power considerations in network meta-analysis
    • Thorlund, K., and, Mills, E. J., (2012) Sample size and power considerations in network meta-analysis. Systematic Reviews 19 (1), 41.
    • (2012) Systematic Reviews , vol.19 , Issue.1 , pp. 41
    • Thorlund, K.1    Mills, E.J.2
  • 32
    • 84856598118 scopus 로고    scopus 로고
    • A Bayesian network meta-analysis on comparisons of enamel matrix derivatives, guided tissue regeneration and their combination therapies
    • Tu, Y. K., Needleman, I., Chambrone, L., Lu, H. K., and, Faggion, C. M. Jr, (2012) A Bayesian network meta-analysis on comparisons of enamel matrix derivatives, guided tissue regeneration and their combination therapies. Journal of Clinical Periodontology 39, 303-314.
    • (2012) Journal of Clinical Periodontology , vol.39 , pp. 303-314
    • Tu, Y.K.1    Needleman, I.2    Chambrone, L.3    Lu, H.K.4    Faggion, Jr.C.M.5
  • 33
    • 72549093086 scopus 로고    scopus 로고
    • Do bone grafts or barrier membranes provide additional treatment effects for infrabony lesions treated with enamel matrix derivatives? A network meta-analysis of randomized-controlled trials
    • Tu, Y. K., Woolston, A., and, Faggion, C. M. Jr, (2010) Do bone grafts or barrier membranes provide additional treatment effects for infrabony lesions treated with enamel matrix derivatives? A network meta-analysis of randomized-controlled trials. Journal of Clinical Periodontology 37, 59-79.
    • (2010) Journal of Clinical Periodontology , vol.37 , pp. 59-79
    • Tu, Y.K.1    Woolston, A.2    Faggion, Jr.C.M.3
  • 34
    • 79952213599 scopus 로고    scopus 로고
    • Systemic antimicrobials adjunctive to a repeated mechanical and antiseptic therapy for aggressive periodontitis: A 6-month randomized controlled trial
    • Varela, V. M., Heller, D., Silva-Senem, M. X., Torres, M. C., Colombo, A. P., and, Feres-Filho, E. J., (2011) Systemic antimicrobials adjunctive to a repeated mechanical and antiseptic therapy for aggressive periodontitis: a 6-month randomized controlled trial. Journal of Periodontology 82, 1121-1130.
    • (2011) Journal of Periodontology , vol.82 , pp. 1121-1130
    • Varela, V.M.1    Heller, D.2    Silva-Senem, M.X.3    Torres, M.C.4    Colombo, A.P.5    Feres-Filho, E.J.6
  • 36
  • 37
    • 77954523029 scopus 로고    scopus 로고
    • Efficacy of amoxicillin and metronidazole combination for the management of generalized aggressive periodontitis
    • Yek, E. C., Cintan, S., Topcuoglu, N., Kulekci, G., Issever, H., and, Kantarci, A., (2010) Efficacy of amoxicillin and metronidazole combination for the management of generalized aggressive periodontitis. Journal of Periodontology 81, 964-974.
    • (2010) Journal of Periodontology , vol.81 , pp. 964-974
    • Yek, E.C.1    Cintan, S.2    Topcuoglu, N.3    Kulekci, G.4    Issever, H.5    Kantarci, A.6
  • 38
    • 84874588704 scopus 로고    scopus 로고
    • The clinical effect of scaling and root planing and the concomitant administration of systemic amoxicillin and metronidazole: A systematic review
    • Zandbergen, D., Slot, D. E., Cobb, C. M., and, Van der Weijden, F. A., (2013) The clinical effect of scaling and root planing and the concomitant administration of systemic amoxicillin and metronidazole: a systematic review. Journal of Periodontology 84, 332-351.
    • (2013) Journal of Periodontology , vol.84 , pp. 332-351
    • Zandbergen, D.1    Slot, D.E.2    Cobb, C.M.3    Van Der Weijden, F.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.