Insulin-Like Growth Factor 1 Treatment of MSCs Attenuates Inflammation and Cardiac Dysfunction Following MI

Inflammation

Volumn 37, Issue 6, 2014, Pages 2156-2163

  Guo, Jun ^a   Zheng, Dong ^a   Li, Wen feng ^a   Li, Hai rui ^a   Zhang, Ai dong ^a   Li, Zi cheng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

Author keywords

mesenchymal stem cells; myocardial infarction; transplantation

Indexed keywords

SOMATOMEDIN C;

ANIMAL; CELL SURVIVAL; DRUG EFFECTS; INFLAMMATION; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; MYOCARDIAL INFARCTION; PATHOLOGY; PHYSIOLOGY; PROCEDURES; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CELL SURVIVAL; INFLAMMATION; INSULIN-LIKE GROWTH FACTOR I; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MYOCARDIAL INFARCTION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84937548834     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9949-3     Document Type: Article

References (25)

1. Toma, C., M.F. Pittenger, K.S. Cahill, B.J. Byrne, and P.D. Kessler. 2002. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105: 93–98.
2. Russo, V., S. Young, A. Hamilton, B.G. Amsden, and L.E. Flynn. 2014. Mesenchymal stem cell delivery strategies to promote cardiac regeneration following ischemic injury. Biomaterials 35(13): 3956–3974.
3. Shake, J.G., P.J. Gruber, W.A. Baumgartner, G. Senechal, J. Meyers, J.M. Redmond, M.F. Pittenger, and B.J. Martin. 2002. Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Annals of Thoracic Surgery 73: 1919–1925.
4. Iso, Y., K.S. Rao, C.N. Poole, A.K. Zaman, I. Curril, B.E. Sobel, J. Kajstura, P. Anversa, and J.L. Spees. 2014. Priming with ligands secreted by human stromal progenitor cells promotes grafts of cardiac stem/progenitor cells after myocardial infarction. Stem Cells 32(3): 674–683.
5. Kollet, O., A. Spiegel, A. Peled, I. Petit, T. Byk, R. Hershkoviz, E. Guetta, G. Barkai, A. Nagler, and T. Lapidot. 2001. Rapid and efficient homing of human CD34(+)CD38(-/low) CXCR4(+) stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2m(null) mice. Blood 97: 3283–3291.
6. Peled, A., I. Petit, O. Kollet, M. Magid, T. Ponomaryov, T. Byk, A. Nagler, H. Ben-Hur, A. Many, L. Shultz, O. Lider, R. Alon, D. Zipori, and T. Lapidot. 1999. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 283: 845–848.
7. Urbich, C., A. Aicher, C. Heeschen, E. Dernbach, W.K. Hofmann, A.M. Zeiher, and S. Dimmeler. 2005. Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. Journal of Molecular and Cellular Cardiology 39: 733–742.
8. Xu, M., R. Uemura, Y. Dai, Y. Wang, Z. Pasha, and M. Ashraf. 2007. In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function. Journal of Molecular and Cellular Cardiology 42: 441–448.
9. Su, E.J., C.L. Cioffi, S. Stefansson, N. Mittereder, M. Garay, D. Hreniuk, and G. Liau. 2003. Gene therapy vector-mediated expression of insulin-like growth factors protects cardiomyocytes from apoptosis and enhances neovascularization. American Journal of Physiology - Heart and Circulatory Physiology 284: H1429–H1440.
10. Guo, J., G. Lin, C. Bao, Z. Hu, H. Chu, and M. Hu. 2008. Insulin-like growth factor 1 improves the efficacy of mesenchymal stem cells transplantation in a rat model of myocardial infarction. Journal of Biomedical Science 15(1): 89–97.
11. Pittenger, M.F., and B.J. Martin. 2004. Mesenchymal stem cells and their potential as cardiac therapeutics. Circulation Research 95(1): 9–20.
12. Ambler, G.R., B.M. Johnston, L. Maxwell, J.B. Gavin, and P.D. Gluckman. 1993. Improvement of doxorubicin induced cardiomyopathy in rats treated with insulin-like growth factor I. Cardiovascular Research 27: 1368–1373.
13. Duerr, R.L., M.D. McKirnan, R.D. Gim, R.G. Clark, K.R. Chien, and J. Ross Jr. 1996. Cardiovascular effects of insulin-like growth factor-1 and growth hormone in chronic left ventricular failure in the rat. Circulation 93: 2188–2196.
14. Kinugawa, S., H. Tsutsui, T. Ide, R. Nakamura, K. Arimura, K. Egashira, and A. Takeshita. 1999. Positive inotropic effect of insulin-like growth factor-1 on normal and failing cardiac myocytes. Cardiovascular Research 43: 157–164.
15. Li, G., M.A. Borger, W.G. Williams, R.D. Weisel, D.A. Mickle, E.D. Wigle, and R.K. Li. 2002. Regional overexpression of insulin-like growth factor-I and transforming growth factor-beta1 in the myocardium of patients with hypertrophic obstructive cardiomyopathy. Journal of Thoracic and Cardiovascular Surgery 123: 89–95.
16. Li, Q., B. Li, X. Wang, A. Leri, K.P. Jana, Y. Liu, J. Kajstura, R. Baserga, and P. Anversa. 1997. Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. Journal of Clinical Investigation 100: 1991–1999.
17. Redaelli, G., A. Malhotra, B. Li, P. Li, E.H. Sonnenblick, P.A. Hofmann, and P. Anversa. 1998. Effects of constitutive overexpression of insulin-like growth factor-1 on the mechanical characteristics and molecular properties of ventricular myocytes. Circulation Research 82: 594–603.
18. Ross Jr., J. 1999. Growth hormone, cardiomyocyte contractile reserve, and heart failure. Circulation 99: 15–17.
19. Welch, S., D. Plank, S. Witt, B. Glascock, E. Schaefer, S. Chimenti, A.M. Andreoli, F. Limana, A. Leri, J. Kajstura, P. Anversa, and M.A. Sussman. 2002. Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice. Circulation Research 90: 641–648.
20. Li, Y., X. Yu, S. Lin, X. Li, S. Zhang, and Y.H. Song. 2007. Insulin-like growth factor 1 enhances the migratory capacity of mesenchymal stem cells. Biochemical and Biophysical Research Communications 356: 780–784.
21. Nagaya, N., T. Fujii, T. Iwase, H. Ohgushi, T. Itoh, M. Uematsu, M. Yamagishi, H. Mori, K. Kangawa, and S. Kitamura. 2004. Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. American Journal of Physiology - Heart and Circulatory Physiology 287: H2670–H2676.
22. Barbash, I.M., P. Chouraqui, J. Baron, M.S. Feinberg, S. Etzion, A. Tessone, L. Miller, E. Guetta, D. Zipori, L.H. Kedes, R.A. Kloner, and J. Leor. 2003. Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation 108: 863–868.
23. Enoki, Cl., H. Otani, D. Sato, T. Okada, R. Hattori, and H. Imamura. 2010. Enhanced mesenchymal cell engraftment by IGF-1 improves left ventricular function in rats undergoing myocardial infarction. International Journal of Cardiology 138(1): 9–18.
24. Haider, H.Kh1., S. Jiang, N.M. Idris, and M. Ashraf. 2008. IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1alpha/CXCR4 signaling to promote myocardial repair. Circulation Research 103(11): 1300–1308.
25. Guo, J., G.S. Lin, C.Y. Bao, Z.M. Hu, and M.Y. Hu. 2007. Anti-inflammation role for mesenchymal stem cells transplantation in myocardial infarction. Inflammation 30(3–4): 97–104.