Ornithine In Vivo Administration Disrupts Redox Homeostasis and Decreases Synaptic Na+, K+-ATPase Activity in Cerebellum of Adolescent Rats: Implications for the Pathogenesis of Hyperornithinemia-Hyperammonemia-Homocitrullinuria (HHH) Syndrome

Cellular and Molecular Neurobiology

Volumn 35, Issue 6, 2015, Pages 797-806

  Zanatta, Ângela ^a   Viegas, Carolina Maso ^a   Hickmann, Fernanda Hermes ^a   de Oliveira Monteiro, Wagner ^a   Sitta, Angela ^b   de Moura Coelho, Daniela ^b   Vargas, Carmen Regla ^a   Leipnitz, Guilhian ^a   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Cerebellum; Homocitrulline; Na+, K+ ATPase activity; Ornithine; Redox homeostasis

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMMONIA; ANTIOXIDANT; BOVINE SERUM ALBUMIN; CATALASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HOMOCITRULLINE; MALONALDEHYDE; METHYLENE BLUE; ORNITHINE; SODIUM; SUPEROXIDE DISMUTASE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; BRAIN MITOCHONDRION; CEREBELLUM; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMEOSTASIS; HYPERORNITHINEMIA HYPERAMMONEMIA HOMOCITRULLINURIA SYNDROME; IN VIVO STUDY; INBORN ERROR OF METABOLISM; INTRACEREBELLAR DRUG ADMINISTRATION; MALE; MICROINJECTION; NEUROPATHOLOGY; NEUROTRANSMISSION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; SYNAPSE; ANIMAL; DEFICIENCY; DRUG EFFECTS; HYPERAMMONEMIA; LIPID PEROXIDATION; METABOLISM; PHYSIOLOGY; SEXUAL MATURATION; UREA CYCLE DISORDERS, INBORN; WISTAR RAT;

RATTUS;

ANIMALS; ANTIOXIDANTS; CEREBELLUM; GLUTATHIONE; HOMEOSTASIS; HYPERAMMONEMIA; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; ORNITHINE; OXIDATION-REDUCTION; RATS; RATS, WISTAR; SEXUAL MATURATION; SODIUM-POTASSIUM-EXCHANGING ATPASE; SYNAPSES; UREA CYCLE DISORDERS, INBORN;

EID: 84937523592     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-015-0173-y     Document Type: Article

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