3-methylcrotonylglycine disrupts mitochondrial energy homeostasis and inhibits synaptic Na +,K +-ATPase activity in brain of young rats

Cellular and Molecular Neurobiology

Volumn 32, Issue 2, 2012, Pages 297-307

  Moura, Alana Pimentel ^a   Ribeiro, César Augusto João ^a   Zanatta, Ângela ^a   Busanello, Estela Natacha Brandt ^a   Tonin, Anelise Miotti ^a   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

3 methylcrotonyl CoA carboxylase deficiency; 3 methylcrotonylglycine; Brain bioenergetics; Reactive species

Indexed keywords

3 METHYLCROTONYLGLYCINE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARBON DIOXIDE; CREATINE KINASE; GLYCINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN MITOCHONDRION; CELL MEMBRANE POTENTIAL; CITRIC ACID CYCLE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENERGY METABOLISM; ENERGY TRANSFER; ENZYME ACTIVITY; IN VITRO STUDY; LIPID PEROXIDATION; NEUROTRANSMISSION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; SYNAPTIC MEMBRANE;

ANIMALS; ANTIOXIDANTS; BRAIN; CARBON DIOXIDE; CEREBRAL CORTEX; CREATINE KINASE; CYTOSOL; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ENERGY METABOLISM; GLYCINE; HOMEOSTASIS; MITOCHONDRIA; RATS; RATS, WISTAR; SODIUM-POTASSIUM-EXCHANGING ATPASE; SYNAPSES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 84864657892     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-011-9761-7     Document Type: Article

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