Neuroprotective effect of ultra-high dose methylcobalamin in wobbler mouse model of amyotrophic lateral sclerosis

Journal of the Neurological Sciences

Volumn 354, Issue 1-2, 2015, Pages 70-74

  Ikeda, Ken ^a   Iwasaki, Yasuo ^a   Kaji, Ryuji ^b  

^a TOHO UNIVERSITY OMORI MEDICAL CENTER   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Homocysteine animal model; Methylcobalamin; Motor neuron disease; Ultra high doses; Wobbler mouse

Indexed keywords

CYANOCOBALAMIN; MECOBALAMIN; NEUROPROTECTIVE AGENT;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BICEPS BRACHII MUSCLE; BRACHIAL PLEXUS; CONTROLLED STUDY; DISEASE COURSE; DRUG MEGADOSE; FORELIMB; MORPHOMETRICS; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; MUSCLE CONTRACTURE; MUSCLE MASS; MUSCLE WEAKNESS; NEUROPROTECTION; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; SKELETAL MUSCLE; SPINAL CORD; SPINAL CORD NERVE CELL; VITAMIN BLOOD LEVEL; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENETICS; MOUSE MUTANT; MUSCLE STRENGTH; PATHOLOGY;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MUSCLE STRENGTH; NEUROPROTECTIVE AGENTS; VITAMIN B 12;

EID: 84937519867     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2015.04.052     Document Type: Article

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