A 3.4-kb Copy-Number Deletion near EPAS1 Is Significantly Enriched in High-Altitude Tibetans but Absent from the Denisovan Sequence

American Journal of Human Genetics

Volumn 97, Issue 1, 2015, Pages 54-66

  Lou, Haiyi ^a   Lu, Yan ^a   Lu, Dongsheng ^a   Fu, Ruiqing ^a   Wang, Xiaoji ^a,b   Feng, Qidi ^a   Wu, Sijie ^a   Yang, Yajun ^c   Li, Shilin ^c   Kang, Longli ^d   Guan, Yaqun ^e   Hoh, Boon Peng ^a,f   Chung, Yeun Jun ^g   Jin, Li ^c   Su, Bing ^h   Xu, Shuhua ^a,b,i  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b SHANGHAITECH UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d XIZANG MINZU UNIVERSITY   (China)

^e XINJIANG MEDICAL UNIVERSITY   (China)

^f UCSI UNIVERSITY   (Malaysia)

^g The Catholic University of Korea   (South Korea)

^h KUNMING INSTITUTE OF ZOOLOGY   (China)

ⁱ FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1;

ALTITUDE; ARTICLE; COPY NUMBER VARIATION; DENISOVAN; DNA FOOTPRINTING; EPAS1 GENE; ETHNIC GROUP; EVOLUTIONARY ADAPTATION; GENE; GENE DELETION; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOMICS; HEMOGLOBIN BLOOD LEVEL; HEMOGLOBIN DETERMINATION; HOMOZYGOTE; HUMAN; HUMAN CELL; INTROGRESSION; MICROARRAY ANALYSIS; POPULATION GENETIC STRUCTURE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TIBETAN (PEOPLE); ADAPTATION; ALGORITHM; ANIMAL; CHINA; DNA SEQUENCE; GENETICS; HOMINID; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; POPULATION GENETICS; PROCEDURES;

ADAPTATION, BIOLOGICAL; ALGORITHMS; ALTITUDE; ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DNA COPY NUMBER VARIATIONS; ETHNIC GROUPS; EVOLUTION, MOLECULAR; GENETICS, POPULATION; HEMOGLOBINS; HOMINIDAE; HUMANS; LINKAGE DISEQUILIBRIUM; MICROARRAY ANALYSIS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; TIBET;

EID: 84937512590     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.05.005     Document Type: Article

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