The secondary bile acid, deoxycholate accelerates intestinal adenoma–adenocarcinoma sequence in Apc min/+ mice through enhancing Wnt signaling

Familial Cancer

Volumn 13, Issue 4, 2014, Pages 563-571

  Cao, Hailong ^a   Luo, Shenhui ^a,b   Xu, Mengque ^a   Zhang, Yujie ^a   Song, Shuli ^a   Wang, Shan ^a   Kong, Xinyue ^a   He, Nana ^a   Cao, Xiaocang ^a   Yan, Fang ^a,c   Wang, Bangmao ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Department of Gastroenterology People s Hospital of Xiangxi Autonomous Prefecture   (China)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apcmin + mice; Deoxycholate; Intestinal tumor; Wnt signaling

Indexed keywords

DEOXYCHOLIC ACID;

ADENOCARCINOMA; ADENOMA; ANIMAL; C57BL MOUSE; COLORECTAL TUMOR; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE; MUTANT MOUSE STRAIN; PATHOLOGY; PHYSIOLOGY; TUMOR SUPPRESSOR GENE; TUNEL ASSAY; WESTERN BLOTTING; WNT SIGNALING PATHWAY;

ADENOCARCINOMA; ADENOMA; ANIMALS; BLOTTING, WESTERN; COLORECTAL NEOPLASMS; DEOXYCHOLIC ACID; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENES, APC; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; WNT SIGNALING PATHWAY;

EID: 84937511480     PISSN: 13899600     EISSN: 15737292     Source Type: Journal    
DOI: 10.1007/s10689-014-9742-3     Document Type: Article

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